scholarly journals Prevalensi dan faktor-faktor risiko yang menyebabkan asma pada anak di RSU GMIM Bethesda Tomohon periode Agustus 2011 – Juli 2016

e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Indri K.T. Runtuwene ◽  
Audrey M.I Wahani ◽  
Vivekenanda Pateda

Abstract: Asthma is a heterogen disease marked by chronic inflammation in the respiratory tract with a history of disturbance of breathing such as wheezing, dyspnea, and cough. This disease can occur at any age. The etiology of asthma is still unclear but there are various risk factors which can cause asthma inter alia sex, history of atopy, change of weather, dust mites, smoke, pet, and food. This study was aimed to obtain the prevalence of asthma and its risk factors in patients aged 0-18 years at GMIM Bethesda Hospital in Tomohon. This was a descriptive retrospective study. Samples were patients aged 0-18 years admitted at the Pediatric Division of GMIM Bethesda Hospital from August 2011 to July 2016. The results showed that the highest prevalence was from August 2011 to July 2012 (21.62%) and the risk factors which affected asthma in children were as follows: male (55.41%), age 5-9 years old (31.08%), history of atopy (52.70%), and change of weather (55.40%). Conclusion: The highest prevalence of ashmatic patients was 21.62% from August 2011 to July 2012. The majority of risk factors were male sex, change of weather, history of atopi, and dust mites.Keywords: asthma, prevalence, risk factor, children Abstrak: Asma merupakan penyakit heterogen yang biasanya ditandai oleh peradangan kronik pada saluran napas dengan riwayat gejala pernapasan seperti mengi, sesak napas, dan batuk yang dapat terjadi pada semua kelompok usia. Etiologi asma masih belum jelas namun terdapat berbagai faktor risiko yang dapat memicu terjadinya asma seperti jenis kelamin, usia, riwayat atopi, perubahan cuaca, tungau debu rumah, paparan asap rokok, binatang piaraan, dan makanan. Penelitian ini bertujuan untuk mengetahui prevalensi asma dan faktor-faktor risiko yang memengaruhi terjadinya athat the highest prevalence wassma di RSU GMIM Bethesda Tomohon. Jenis penelitian ialah deskriptif retrospektif. Sampel penelitian ialah pasien anak usia 0-18 tahun dengan diagnosis utama asma yang dirawat di Bagian Ilmu Kesehatan Anak RSU GMIM Bethesda Tomohon pada periode Agustus 2011-Juli 2016. Hasil penelitian menunjukkan prevalensi terbanyak pada periode Agustus 2011-Juli 2012 (21,62%) dan faktor risiko yang memengaruhi asma pada anak berupa jenis kelamin laki-laki (55,41%), usia 5-9 tahun (31,08%), riwayat atopi (54,05%), tungau debu rumah (52,70%), dan perubahan cuaca (55,40%). Simpulan: Kejadian asma terbanyak terjadi pada periode Agustus 2011-Juli 2012 sebesar 21,62%. Faktor risiko tersering ditemukan ialah jenis kelamin laki-laki, perubahan cuaca, riwayat atopi, dan tungau debu rumah. Kata kunci: asma, prevalensi, faktor risiko, anak

2017 ◽  
Vol 38 (11-12) ◽  
pp. 265
Author(s):  
Ina Rosalina ◽  
Cissy B Kartasasmita ◽  
Myrna Soepriadi

To determine the asthma prevalence and the role of some risk factors of asthma in children aged 13-14 years in Bandung, a study was conducted from April to May 1996 using using the International Study of Asthma and Allergies in childhood (ISAAC) written questionnaire. The study was conducted in 12 Junior high schools (SMP), selected by multistage population random sampling from 6 district in municipality of Bandung. A total of 3118 questionnaires were collected. The cumulative prevalence of asthma was 6.4% and the 12 month prevalence was 2.6%. The prevalence was higher in male, with a ratio of male : female of 1.48:1. The prevalence of asthma increased significantly in children with history of atopy in the family (OR 6.1; p<0.01); however no significant differences was found between children with one or both parents having history of atopy. The prevalence of asthma in smoking children, maternal and room mates had also increased significantly (OR = 2.1; 2.3; 2.6 and p=<0.05;<0.01;<0.01 respectively). However there was no significant effect of paternal smoking (p=0.074). The use of mosquito spray in the bedroom and having pets showed no effect on the prevalence of asthma (p=0.86 and 0.56 respectively).


2021 ◽  
Vol 67 (3) ◽  
pp. 21-28
Author(s):  
Yusuke Ohara ◽  
Tsuyoshi Enomoto ◽  
Yohei Owada ◽  
Daichi Kitaguchi ◽  
Katsuji Hisakura ◽  
...  

BACKGROUND: Stomal mucocutaneous separation (SMS) is a serious and common short-term and long-term complication of ostomy surgery, but optimal methods to help prevent it have not been established. The authors hypothesized that seromuscular-dermal (SM-D) suturing may be better than all layer-dermal (AL-D) suturing to help prevent SMS. METHODS: This retrospective study evaluated the short-term SMS rate of patients who underwent colostomy or ileostomy surgery between 2015 and 2019. Patient demographics, medical and surgical history variables, as well as SMS outcomes were abstracted. Postoperative SMS severity was categorized by extent as follows: grade A (mild), grade B (moderate), and grade C (severe). RESULTS: In total, 105 patients (AL-D group, 45 patients; SM-D group, 60 patients) were enrolled in the study. SMS occurred in 24 patients (23%). The overall SMS rate was 18% (n = 11) in the SM-D group and 29% (n = 13) in the AL-D group (P = .202). The occurrence of severe (grade C) or moderate and severe SMS (grades B + C) in the SM-D compared with the AL-D group was significantly different (2% vs 16% [P = .011] and 10% vs 24% [P = .047], respectively). A history of steroid use was a risk factor for moderate and severe SMS (P = .016, odds ratio 5.694). Stomal height ≤1 cm was a a risk factor for all cases of SMS (P = .037, odds ratio 2.650). AL-D suture technique and a history of steroid use were independent risk factors for severe and moderate plus severe SMS (P = .021, odds ratio 12.844 and P = .027, odds ratio 4.808, respectively). CONCLUSION: In this study, use of the AL-D suturing technique and a history of steroid use were independent risk factors for the short-term development of moderate or severe SMS. Patients whose stoma was secured using the SM-D technique had a significantly lower rate of moderate or severe SMS.


2020 ◽  
Author(s):  
Xun Chen ◽  
Minjing Yang ◽  
Shengzhu Huang ◽  
Xiaolian Qin ◽  
Zhijian Pan ◽  
...  

Abstract Background: The factors that cause recurrent wheezing in children are complex, and premature delivery may be one of these factors. Little is known about early wheezing in preterm infants.Methods: Data were sourced from 1616 children born between 2007 and 2013 from 8 hospitals in Guangxi, China. All children were followed up by telephone or questionnaire through the sixth year of life. Children were grouped by gestational age (GA): Group A, GA ≤ 32 weeks; Group B, 32 weeks < GA < 37 weeks; and Group C, 37 weeks ≤ GA < 42 weeks.Results: The incidences and risk factors for early wheezing in preterm infants were analysed. The incidences of early wheezing were as follows: Group A > Group B > Group C. The incidence of persistent early wheezing in Group A or Group B was significantly higher than that in Group C, respectively. SGA (95% CI: 1.097 to 7.519) was a risk factor for early wheezing in group A. Male sex (95% CI: 1.595 to 4.501) and family history of allergies (95% CI: 1.207 to 3.352) were risk factors for early wheezing in group B.Conclusions: 1. New-borns with younger GAs had a higher risk of early wheezing. 2. The incidence of persistent early wheezing for preterm infants (GA ≤ 32 weeks and 32 weeks < GA < 37 weeks) was higher than that for full-term infants (37 weeks ≤ GA < 42 weeks). 3. SGA was a risk factor for early wheezing in preterm infants with a GA ≤ 32 weeks. 4. Male sex, personal history of allergies and family history of allergies were all possible factors affecting early wheezing in preterm infants with a GA > 32 weeks but < 37 weeks and full-term infants. Among them, male sex and family history of allergies were risk factors for early wheezing. 5. Mode of delivery, passive smoking, breastfeeding and invasive mechanical ventilation were not possible risk factors for early wheezing in infants of different GAs.


2007 ◽  
Vol 6 (4) ◽  
pp. 112-116
Author(s):  
I. N. Gaimolenko ◽  
N. L. Potapova

Risk factors for bronchial asthma in children of Chita Region were studied. According to the literature data, 12 clinical-anamnestic characteristics were suggested to be risk factors for bronchial asthma. Prevalence of risk factors was assessed in 72 children with severe asthma, 60 children with moderate, and 58 children with mild bronchial asthma. Odds ratios (OR) with the 95% confident interval for each factor were calculated. Factors with predominance in the asthma group included: parental history of asthma (OR = 16.2), congenital abnormalities and complications of pregnancy and labor (OR = 1.9), prenatal lesion of central nervous system (OR = 2.8), recurrent respiratory tract infections (OR = 12.4), coexisting atopic dermatitis (OR = 1.8), passive smoking (OR = 2.8), and food sensitization (OR = 7.7). The findings can be used to calculate individual risks in a population for prediction of development of this pathology and for its timely prevention.


2021 ◽  
Vol 39 (3_suppl) ◽  
pp. 189-189
Author(s):  
Haejin In ◽  
Patricia Friedmann ◽  
Srawani Sarkar ◽  
Bruce Rapkin ◽  
Philip E. Castle ◽  
...  

189 Background: Gastric cancer (GC) is a high mortality cancer in the US. Differences in risk factors by anatomic location and race/ethnicity have been suggested but remain understudied in the US population. Methods: The Multiethnic Cohort (MEC) is a prospective cohort study that collected data on 5 racial/ethnic groups [Whites (W), Blacks (B), Latino (L), Japanese-American (JA), and Hawaiian (HA)] from Hawaii and Los Angeles in 1993-1996. Participants completed a detailed baseline survey and were followed for development of incident cancer. Cox regression models were used to calculate hazard ratios (HR) and 95% confidence intervals (CI) to identify GC risk factors by anatomic location (cardia, non-cardia) and by race/ethnicity. Results: Data from 192,626 participants was available. The cohort was 25% W, 17% B, 23% L, 28% JA, and 7% HA. During a median follow up of 20.3 years, 1,109 non-cardia and 201 cardia incident GCs were diagnosed. Older age (per year, non-cardia HR 1.08, 95% CI 1.07-1.92; cardia HR 1.06, 95% CI 1.05-1.09), male sex (non-cardia HR 1.6, 95% CI 1.4-1.8; cardia HR 3.0, 95% CI 2.1-4.4), and current (non-cardia HR 1.7, 95% CI 1.5-2.2, cardia HR 3.4, 95% CI 2.2-5.3) or former (non-cardia HR 1.3, 95% CI 1.1-1.5; cardia HR 2.0, 95% CI 1.3-2.9) smoking were associated with both cancer types. Notably, race/ethnicity (ref W: B HR 3.0, 95% CI 2.2-4.0; L HR 2.5, 95% CI 1.8-3.3; JA HR 3.9, 95% CI 3.0-5.1; HA HR 3.9, 95% CI 2.8-5.5), foreign-born (ref: self & parents US born: HR 1.3 95% CI 1.1-1.7), and family history of GC (OR 1.9, 95% CI 1.5-2.3) were associated with non-cardia GC. BMI ≥30 (HR 1.6, 95% CI 1.1-2.3), having ≥1 drink/week (HR 1.6, 95% CI 1.1-2.3), and being JA (ref W: HR 1.9, 95% CI 1.2-2.9) were associated with cardia GC. Risk factors other than age differed by race/ethnicity for non-cardia GC. Male sex was a risk factor for B, L and JA only. Having less than a high school education was a risk factor for B and JA only, smoking a risk factor for L and JA only, and having diabetes a risk factor for B only. Being in the highest sodium intake quartile was a risk factor among W and HA. A family history of GC was a risk factor for W, L, and JA. Having foreign-born parents was a risk factor for W and being foreign-born was a risk factor for JA. Conclusions: GC risk factors differ between subtypes and, for non-cardia, between race/ethnic groups. These differences provide an insight into the etiology of GC and the disproportionate incidence rates in high-risk groups, potentially aiding in the design of targeted intervention strategies.


Circulation ◽  
2015 ◽  
Vol 131 (suppl_2) ◽  
Author(s):  
Arbia A Gorrab ◽  
Asma Abed Bouaziz ◽  
Linda Spigelblatt ◽  
Anne Fournier ◽  
Nagib Dahdah

Background: The real incidence of Kawasaki disease (KD) in the Maghreb countries (Morocco, Algeria, and Tunisia) is unknown. It is estimated low according to the literature. However, the number of Maghrebi children living in Quebec (Qc) affected by KD seems important. We sought to determine the incidence of KD among Maghrebi children in Qc, Canada, and to study its epidemiological and clinical features and to clarify possible risk factors related or superimposed to their immigration. Methods: A retrospective study of KD in Maghrebi children living in Qc (n=24) (1996-2013), compared to reports from Fes, Morocco (n=23) a doctoral thesis published in 2010 (2001-2009) and from Tunisia (n=31) collected in five university hospitals with four from the Great Tunis and one from Nabeul city (1996-2013). There are no reports available from Algeria. The “country of origin” specific population in the Province of Qc was obtained from Statistics Canada. Results: The annualized incidence rate (AIR) of KD among Maghrebi children in Qc was 9.58/100,000 children under 5 years(Standard-Denominator (SD)).This is 6 times higher in Qc (5.57/SD and 19.02/SD among Tunisian and Moroccan descents) vs Tunisia (Nabeul Governorate) and Morocco (Fes) (0.95/SD and 3.15/SD). Personal and family history of allergy were significantly higher in Qc 42% (10/24) and 75% (18/24), respectively, whereas these features were reported near 0% in both reports from Morocco and Tunisia. The prevalence of incomplete KD criteria was relatively high in the 3 series 46% (11/24) in Qc vs 43% (10/23) and 35% (11/31); (p=NS). Diagnosis was late (gt day 10 of fever) in 1/24(4%) in Qc vs 7/23 (30%) in Morocco and 11/31 (35%) in Tunisia; (p 0.01). IVIG were administered in the acute phase to all patients in Qc, 5/23 in Morocco and 28/31 in Tunisia. However coronary complications were more common in Qc 42% (10/24) vs 22% (5/23) vs 19% (6/31) (p=0.02). Aneurysms were significantly associated with the incomplete form in the 3 groups (p=0.01). Conclusions: The observed AIR of KD in the Maghreb community in Qc is higher than the countries of origin where underdiagnosis is possible. Atopy may still be a risk factor in Qc. The coronary artery disease seems linked not only to therapeutic delay but also to the underlying terrain.


Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Rakhee Lalla ◽  
Ryan Dunlow ◽  
Karen L Yarbrough ◽  
Prachi Mehndiratta ◽  
Michael S Phipps ◽  
...  

Introduction: The AHA notes that more than 76% of strokes are the first occurrence. There are class 1 recommendations for the management of common risk factors such as atrial fibrillation (AF), hyperlipidemia (HLD), hypertension (HTN), diabetes (DM), and vascular disease. The purpose of this study is to investigate the percentage of large vessel strokes that are potentially preventable with adequate management of vascular risk factors. Methods: A retrospective chart review was conducted on all patients undergoing endovascular therapy (EVT) from 2012-2019. Data was collected on vascular risk factors present prior to admission including HTN, DM, HLD, AF, and smoking. Preventable stroke was defined as having at least one of the following: untreated AF, untreated HLD, poorly controlled HTN (presence of left ventricular hypertrophy on transthoracic echo), history of vascular disease not on an antiplatelet agent, poorly controlled DM (A1c>10), current smoking. Groups were compared based on age, sex and 90 day functional outcomes, with favorable outcome defined as mRS ≤ 2. Results: Our sample included 396 patients who underwent EVT (mean age 65, 50% female). 42% of patients with Afib were not on anticoagulation, 31% of patients with HLD were untreated, 39% of patients with HTN were poorly controlled, 27% of patients with a history of vascular disease were not on an antiplatelet, 14% of patients with DM were poorly controlled, and 46% of all patients were smokers. In total, 78% of patients had at least 1 poorly controlled risk factor and 37% had at least 2. There was no difference in rates of preventable stroke between males and females (48% vs 52%, p=0.30) and between age groups above and below 70 (40% vs 60%, p=0.68). 64% of patients with well controlled risk factors had a favorable outcome compared to 51% with at least one poorly controlled risk factor (p=0.03). Conclusions: Our data suggests that despite guidelines on management of vascular risk factors, a large number of these are poorly controlled prior to admission for large vessel stroke, leading to a potentially preventable procedure. Not only could improved primary prevention save the wide array of resources utilized in EVT, but it could also influence long term outcomes in this cohort of patients.


2019 ◽  
Vol 131 (3) ◽  
pp. 941-948
Author(s):  
Eric S. Nussbaum ◽  
Kevin Kallmes ◽  
Jodi Lowary ◽  
Leslie A. Nussbaum

OBJECTIVEUndiagnosed hepatitis C virus (HCV) and HIV in patients present risks of transmission of bloodborne infections to surgeons intraoperatively. Presurgical screening has been suggested as a protocol to protect surgical staff from these pathogens. The authors sought to determine the incidence of HCV and HIV infection in elective craniotomy patients and analyze the cost-effectiveness of universal and risk factor–specific screening for protection of the surgical staff.METHODSAll patients undergoing elective craniotomy between July 2009 and July 2016 at the National Brain Aneurysm Center who did not refuse screening were included in this study. The authors utilized rapid HCV and HIV tests to screen patients prior to elective surgery, and for each patient who tested positive using the rapid HCV or HIV test, qualitative nucleic acid testing was used to confirm active viral load, and risk factor information was collected. Patients scheduled for nonurgent surgery who were found to be HCV positive were referred to a hepatologist for preoperative treatment. The authors compared risk factors between patients who tested positive on rapid tests, patients with active viral loads, and a random sample of patients who tested negative. The authors also tracked the clinical and material costs of HCV and HIV rapid test screening per patient for cost-effectiveness analysis and calculated the cost per positive result of screening all patients and of screening based on all patient risk factors that differed significantly between patients with and those without positive HCV test results.RESULTSThe study population of patients scheduled for elective craniotomy included 1461 patients, of whom 22 (1.5%) refused the screening. Of the 1439 patients screened, 15 (1.0%) tested positive for HCV using rapid HCV screening; 9 (60%) of these patients had active viral loads. No patient (0%) tested positive for HIV. Seven (77.8%) of the 9 patients with active viral loads underwent treatment with a hepatologist and were referred back for surgery 3–6 months after sustained virologic response to treatment, but the remaining 2 patients (22.2%) required urgent surgery. Of the 9 patients with active viral loads, 1 patient (11%) had a history of both intravenous drug abuse and tattoos. Two of the 9 patients (22%) had tattoos, and 3 (33%) were born within the age-screening bracket (born 1945–1965) recommended by the Centers for Disease Control and Prevention. Rates of smoking differed significantly (p < 0.001) between patients who had active viral loads of HCV and patients who were HCV negative, and rates of smoking (p < 0.001) and IV drug abuse (p < 0.01) differed significantly between patients who were HCV rapid-test positive and those who were HCV negative. Total screening costs (95% CI) per positive result were $3,877.33 ($2,348.05–$11,119.28) for all patients undergoing HCV rapid screening, $226.29 ($93.54–$312.68) for patients with a history of smoking, and $72.00 ($29.15–$619.39) for patients with a history of IV drug abuse.CONCLUSIONSThe rate of undiagnosed HCV infection in this patient population was commensurate with national levels. While the cost of universal screening was considerable, screening patients based on a history of smoking or IV drug abuse would likely reduce costs per positive result greatly and potentially provide cost-effective identification and treatment of HCV patients and surgical staff protection. HIV screening found no infected patients and was not cost-effective.


Author(s):  
Denny Khusen

Objective: To analyze risk factor, both clinical and laboratory findings, associated with maternal mortality from severe preeclampsia and eclampsia in Atma Jaya Hospital. Methods: This was a retrospective case control study. All medical records of maternal death associated with severe preeclampsia and eclampsia between 1st January 2009 and 31st December 2011 were obtained and then information about risk factors were collected and tabulated. Risk factor analyzed were maternal age, gestational age, parity, coexisting medical illness (hypertension), antenatal examination status, maternal complications, systolic and diastolic blood pressure at admission, and admission laboratory data. Results: There were 19 maternal deaths associated with severe preeclampsia and eclampsia during period of study (Consisted of 6 cases of eclampsia and 13 cases of severe preeclampsia). Maternal mortality rate for severe preeclampsia and eclampsia were 16.7% and 33.3% respectively. Multivariate analysis identified the following risk factors associated with maternal death: gestation age <32 week, history of hypertension, thrombocyte count < 100.0000/μl, post partum bleeding, acute pulmonary edema, HELLP syndrome, and sepsis. Conclusion: In this study, we found that gestational age, history of hypertension, and platelet count are the cause of maternal mortality. Maternal complications associated with maternal mortality are post partum bleeding, acute pulmonary edema, HELLP syndrome, and sepsis. [Indones J Obstet Gynecol 2012; 36-2: 90-4] Keywords: eclampsia, maternal mortality, preeclampsia


2018 ◽  
Vol 25 (1) ◽  
pp. 6 ◽  
Author(s):  
Amelia Rahmah Kartika ◽  
Muhammad Ilham Aldika Akbar ◽  
Pirlina Umiastuti

Objectives: to determine which of the risk factors above associated with the occurrence of severe preeclampsia at dr. Soetomo Hospital, Surabaya during 2015.Materials and Methods: The type and design of the study were analytic and retrospective. This study was held in the dr. Soetomo Hospital from April until November 2016. The instrument of the study was the medical records then being coded and analysed. The samples were 134 pregnant women, consisting of 67 pregnant women with severe preeclampsia as cases and 67 pregnant women as controls.Results: Maternal obesity (OR= 5,786; 95% CI: 2,300–14,555), history of hypertension (OR= 6,693; 95% CI: 1,848–24,237) and secondary elderly primi (OR= 6,384; 95% CI: 1,357–30,031) are associated with the development of severe preeclampsia.Conclusion: In conclusion, the significant risk factors of severe preeclampsia in dr. Soetomo Hospital Surabaya during 2015 are obesity, history of hypertension and secondary elderly primi variables.


Sign in / Sign up

Export Citation Format

Share Document