Prevalence and Risk Factors of Asthma in Children Aged 13-14 Years

To determine the asthma prevalence and the role of some risk factors of asthma in children aged 13-14 years in Bandung, a study was conducted from April to May 1996 using using the International Study of Asthma and Allergies in childhood (ISAAC) written questionnaire. The study was conducted in 12 Junior high schools (SMP), selected by multistage population random sampling from 6 district in municipality of Bandung. A total of 3118 questionnaires were collected. The cumulative prevalence of asthma was 6.4% and the 12 month prevalence was 2.6%. The prevalence was higher in male, with a ratio of male : female of 1.48:1. The prevalence of asthma increased significantly in children with history of atopy in the family (OR 6.1; p<0.01); however no significant differences was found between children with one or both parents having history of atopy. The prevalence of asthma in smoking children, maternal and room mates had also increased significantly (OR = 2.1; 2.3; 2.6 and p=<0.05;<0.01;<0.01 respectively). However there was no significant effect of paternal smoking (p=0.074). The use of mosquito spray in the bedroom and having pets showed no effect on the prevalence of asthma (p=0.86 and 0.56 respectively).

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Association between bronchial asthma in atopic children and their number of siblings

Paediatrica Indonesiana ◽

10.14238/pi54.5.2014.289-93 ◽

2014 ◽

Vol 54 (5) ◽

pp. 289

Author(s):

Johan El Hakim Siregar ◽

Lily Irsa ◽

Supriatmo Supriatmo ◽

Sjabaroeddin Loebis ◽

Rita Evalina

Keyword(s):

Elementary Schools ◽

Bronchial Asthma ◽

Inverse Relationship ◽

International Study ◽

Clinical History ◽

Asthma Prevalence ◽

Chi Square ◽

Chi Square Test ◽

History Of ◽

Asthma In Children

Background The prevalence of asthma in children has increased in many countries. Environmental factors are believed to play an important role and an inverse relationship between number of siblings and atopic disorders has been observed.Objective To assess for an association between bronchial asthma in atopic children and their number of siblings.Methods A cross-secrional study was conducted from June to November 2010 in three elementary schools in Medan, North Sumatera. Trace cards from the Allergy-Immunology Indonesian Pediatric Association (IDAI) Working Group and questionnaires on the clinical history of atopy were used to screen children with the risk of atopy. The International Study of .Asthma and Allergies in Childhood (ISAAC) questionnaire to screen for bronchial asthma was distributed to children aged 7-10 years with a history of asthma, allergic rhinitis or atopic dermatitis. Subjects were divided into two groups, those with <3 siblings and those with 2:3 siblings. Chi-square test was used to analyze differences in bronchial asthma prevalence between the two groups.Results Ninety-six subjects enrolled in the study, with 48 subjects per group. The prevalence of bronchial asthma was significantly higher in atopic children who had <3 siblings than in children with 2:3 siblings (73.5% and 26.5%, respectively; P=0.04).Conclusion Bronchial asthma was significantly more frequent in children with less than 3 siblings compared to those with 3 or more siblings.

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Prevalensi dan faktor-faktor risiko yang menyebabkan asma pada anak di RSU GMIM Bethesda Tomohon periode Agustus 2011 – Juli 2016

e-CliniC ◽

10.35790/ecl.4.2.2016.14453 ◽

2016 ◽

Vol 4 (2) ◽

Author(s):

Indri K.T. Runtuwene ◽

Audrey M.I Wahani ◽

Vivekenanda Pateda

Keyword(s):

Risk Factors ◽

Risk Factor ◽

Retrospective Study ◽

Respiratory Tract ◽

Chronic Inflammation ◽

Asthma Prevalence ◽

Dust Mites ◽

History Of ◽

Male Sex ◽

Asthma In Children

Abstract: Asthma is a heterogen disease marked by chronic inflammation in the respiratory tract with a history of disturbance of breathing such as wheezing, dyspnea, and cough. This disease can occur at any age. The etiology of asthma is still unclear but there are various risk factors which can cause asthma inter alia sex, history of atopy, change of weather, dust mites, smoke, pet, and food. This study was aimed to obtain the prevalence of asthma and its risk factors in patients aged 0-18 years at GMIM Bethesda Hospital in Tomohon. This was a descriptive retrospective study. Samples were patients aged 0-18 years admitted at the Pediatric Division of GMIM Bethesda Hospital from August 2011 to July 2016. The results showed that the highest prevalence was from August 2011 to July 2012 (21.62%) and the risk factors which affected asthma in children were as follows: male (55.41%), age 5-9 years old (31.08%), history of atopy (52.70%), and change of weather (55.40%). Conclusion: The highest prevalence of ashmatic patients was 21.62% from August 2011 to July 2012. The majority of risk factors were male sex, change of weather, history of atopi, and dust mites.Keywords: asthma, prevalence, risk factor, children Abstrak: Asma merupakan penyakit heterogen yang biasanya ditandai oleh peradangan kronik pada saluran napas dengan riwayat gejala pernapasan seperti mengi, sesak napas, dan batuk yang dapat terjadi pada semua kelompok usia. Etiologi asma masih belum jelas namun terdapat berbagai faktor risiko yang dapat memicu terjadinya asma seperti jenis kelamin, usia, riwayat atopi, perubahan cuaca, tungau debu rumah, paparan asap rokok, binatang piaraan, dan makanan. Penelitian ini bertujuan untuk mengetahui prevalensi asma dan faktor-faktor risiko yang memengaruhi terjadinya athat the highest prevalence wassma di RSU GMIM Bethesda Tomohon. Jenis penelitian ialah deskriptif retrospektif. Sampel penelitian ialah pasien anak usia 0-18 tahun dengan diagnosis utama asma yang dirawat di Bagian Ilmu Kesehatan Anak RSU GMIM Bethesda Tomohon pada periode Agustus 2011-Juli 2016. Hasil penelitian menunjukkan prevalensi terbanyak pada periode Agustus 2011-Juli 2012 (21,62%) dan faktor risiko yang memengaruhi asma pada anak berupa jenis kelamin laki-laki (55,41%), usia 5-9 tahun (31,08%), riwayat atopi (54,05%), tungau debu rumah (52,70%), dan perubahan cuaca (55,40%). Simpulan: Kejadian asma terbanyak terjadi pada periode Agustus 2011-Juli 2012 sebesar 21,62%. Faktor risiko tersering ditemukan ialah jenis kelamin laki-laki, perubahan cuaca, riwayat atopi, dan tungau debu rumah. Kata kunci: asma, prevalensi, faktor risiko, anak

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Risk factors for bronchial asthma in children in Chita Region

Bulletin of Siberian Medicine ◽

10.20538/1682-0363-2007-4-112-116 ◽

2007 ◽

Vol 6 (4) ◽

pp. 112-116

Author(s):

I. N. Gaimolenko ◽

N. L. Potapova

Keyword(s):

Risk Factors ◽

Bronchial Asthma ◽

Asthma Prevalence ◽

Parental History ◽

History Of ◽

Asthma In Children ◽

Tract Infections ◽

Food Sensitization ◽

Asthma Group ◽

Recurrent Respiratory Tract Infections

Risk factors for bronchial asthma in children of Chita Region were studied. According to the literature data, 12 clinical-anamnestic characteristics were suggested to be risk factors for bronchial asthma. Prevalence of risk factors was assessed in 72 children with severe asthma, 60 children with moderate, and 58 children with mild bronchial asthma. Odds ratios (OR) with the 95% confident interval for each factor were calculated. Factors with predominance in the asthma group included: parental history of asthma (OR = 16.2), congenital abnormalities and complications of pregnancy and labor (OR = 1.9), prenatal lesion of central nervous system (OR = 2.8), recurrent respiratory tract infections (OR = 12.4), coexisting atopic dermatitis (OR = 1.8), passive smoking (OR = 2.8), and food sensitization (OR = 7.7). The findings can be used to calculate individual risks in a population for prediction of development of this pathology and for its timely prevention.

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Protective Factors and Suicidality in Members of Arab Kindred

Crisis ◽

10.1027/0227-5910/a000116 ◽

2012 ◽

Vol 33 (2) ◽

pp. 80-86 ◽

Cited By ~ 6

Author(s):

Sami Hamdan ◽

Nadine Melhem ◽

Israel Orbach ◽

Ilana Farbstein ◽

Mohammad El-Haib ◽

...

Keyword(s):

Risk Factors ◽

Protective Factors ◽

Suicidal Behavior ◽

Composite International Diagnostic Interview ◽

Diagnostic Interview ◽

Suicidal Risk ◽

Arab Population ◽

Psychiatric Interview ◽

History Of

Background: Relatively little is known about the role of protective factors in an Arab population in the presence of suicidal risk factors. Aims: To examine the role of protective factors in a subsample of in large Arab Kindred participants in the presence of suicidal risk factors. Methods: We assessed protective and risk factors in a sample of 64 participants (16 suicidal and 48 nonsuicidal) between 15 and 55 years of age, using a comprehensive structured psychiatric interview, the Composite International Diagnostic Interview (CIDI), self-reported depression, anxiety, hopelessness, impulsivity, hostility, and suicidal behavior in first-degree and second-relatives. We also used the Religiosity Questionnaire and suicide attitude (SUIATT) and multidimensional perceived support scale. Results: Suicidal as opposed to nonsuicidal participants were more likely to have a lifetime history of major depressive disorder (MDD) (68.8% vs. 22.9% χ2 = 11.17, p = .001), an anxiety disorder (87.5% vs. 22.9, χ2 = 21.02, p < .001), or posttraumatic stress disorder (PTSD) (25% vs. 0.0%, Fisher’s, p = .003). Individuals who are otherwise at high risk for suicidality have a much lower risk when they experience higher perceived social support (3.31 ± 1.36 vs. 4.96 ± 1.40, t = 4.10, df = 62, p < .001), and they have the view that suicide is somehow unacceptable (1.83 ± .10 vs. 1.89 ± .07, t = 2.76, df = 60, p = .008). Conclusions: Taken together with other studies, these data suggest that the augmentation of protective factors could play a very important role in the prevention of incidental and recurrent suicidal behavior in Arab populations, where suicidal behavior in increasing rapidly.

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Stress, Cortisol and Suicide Risk

10.31234/osf.io/92b7z ◽

2019 ◽

Author(s):

Daryl Brian O'Connor

Keyword(s):

Risk Factors ◽

Suicidal Behavior ◽

Suicide Risk ◽

Stressful Events ◽

Additional Risk ◽

Global Health Issue ◽

History Of ◽

Hpa Axis Activity ◽

The Impact

Suicide is a global health issue accounting for at least 800,000 deaths per annum. Numerous models have been proposed that differ in their emphasis on the role of psychological, social, psychiatric and neurobiological factors in explaining suicide risk. Central to many models is a stress-diathesis component which states that suicidal behavior is the result of an interaction between acutely stressful events and a susceptibility to suicidal behavior (a diathesis). This article presents an overview of studies that demonstrate that stress and dysregulated hypothalamic-pituitary-adrenal (HPA) axis activity, as measured by cortisol levels, are important additional risk factors for suicide. Evidence for other putative stress-related suicide risk factors including childhood trauma, impaired executive function, impulsivity and disrupted sleep are considered together with the impact of family history of suicide, perinatal and epigenetic influences on suicide risk.

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GENRE OF AUTOBIOGRAPHICAL NOVEL IN THE OSSETIAN CHILDREN’S LITERATURE

10.23671/vnc.2020.8.58150 ◽

2020 ◽

Author(s):

А.Б. Бритаева

Keyword(s):

Children's Literature ◽

Present Article ◽

Children’S Literature ◽

Final Part ◽

Xxth Century ◽

The Family ◽

Moral Aspect ◽

History Of ◽

Post War

В представленной статье на материале произведений Музафера Дзасохова известного современного осетинского писателя, поэта, публициста, переводчика, рассматриваются художественные особенности лирической прозы, а именно, автобиографической повести в осетинской детской литературе. Повесть Весенние звезды (1973) и ее продолжение На берегу Уршдона Барагун (1981) стали началом эпопеи о жизни отдельно взятой семьи, а на их примере всей страны в тяжелые послевоенные годы. В качестве одной из важнейших констант художественного мира писателя рассматривается образ детства. В ходе анализа особое внимание уделяется преобладанию нравственного аспекта, актуализации проблемы регулятивно-воспитательной функции национального этикета, ценностно-нормативных ориентиров осетинской ментальности. С опорой на биографический и историко-генетический методы, основное внимание в исследовании акцентируется на темах послевоенного детства, роли семьи и общества в формировании нравственных ориентиров, в становлении личности, образе матери, теме памяти, а также на художественном осмыслении этих проблем и тем в автобиографических повестях писателя. Типологически воплощение детской темы в творчестве М. Дзасохова во многом опирается на традицию изображения детства в русской автобиографической прозе XX в. В заключительной части сформулированы выводы, отражающие особенности лирической прозы в творчестве М. Дзасохова, обозначено место автобиографических повестей автора в контексте осетинской детской литературы второй половины XX века.Актуальность и научная новизна работы обусловлены недостаточной исследованностью истории и проблем осетинской детской литературы. Результаты исследования могут быть использованы при написании истории осетинской детской литературы. The present article examines the artistic features of lyrical prose, namely, autobiographical story in the Ossetian childrens literature in the works of Muzafer Dzasokhov, a well-known modern Ossetian writer, poet, publicist, translator. The story Spring Stars (1973) and its continuation - On the Bank of Ursdon Baragun ... (1981) marked the beginning of an epic about the life of a family, and via their fates the author shows life of the whole country in the difficult post-war years. The theme of childhood is considered as one of the most important constants of the writers artistic world. In the course of the analysis, special attention is paid to the predominance of the moral aspect, the actualization of the problem of the regulatory and educational function of national etiquette, the value and normative guidelines of the Ossetian mentality. The focus of the study is based on biographical and historical-genetic methods and highlights the themes of post-war childhood, the role of the family and society in the formation of moral guidelines, in the formation of personality, the image of the mother, the theme of memory, as well as on the artistic understanding of these problems and topics in autobiographical novels of the writer. Typologically, the embodiment of the childrens theme in the works of M. Dzasokhov is largely based on the tradition of depicting childhood in Russian autobiographical prose of the XXth century. The formulated conclusions in the final part reflect the peculiarities of lyrical prose in the works of M. Dzasokhov, the place of the authors autobiographical stories is indicated in the context of Ossetian childrens literature of the second half of the XXth century. The relevance and scientific novelty of the work are due to insufficient research on the history and problems of Ossetian childrens literature. The results of the study can be used in writing the history of Ossetian childrens literature.

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Is there a link between glucose levels and heart failure? An update

Arquivos Brasileiros de Endocrinologia & Metabologia ◽

10.1590/s0004-27302010000500010 ◽

2010 ◽

Vol 54 (5) ◽

pp. 488-497 ◽

Cited By ~ 6

Author(s):

Arnaldo Schainberg ◽

Antônio Ribeiro-Oliveira Jr. ◽

José Marcio Ribeiro

Keyword(s):

Risk Factors ◽

Heart Failure ◽

Epidemiological Studies ◽

Left Ventricular ◽

Glucose Levels ◽

Factors Analysis ◽

History Of ◽

Cv Disease ◽

The Relationship

It has been well documented that there is an increased prevalence of standard cardiovascular (CV) risk factors in association with diabetes and with diabetes-related abnormalities. Hyperglycemia, in particular, also plays an important role. Heart failure (HF) has become a frequent manifestation of cardiovascular disease (CVD) among individuals with diabetes mellitus. Epidemiological studies suggest that the effect of hyperglycemia on HF risk is independent of other known risk factors. Analysis of datasets from populations including individuals with dysglycemia suggests the pathogenic role of hyperglycemia on left ventricular function and on the natural history of HF. Despite substantial epidemiological evidence of the relationship between diabetes and HF, data from available interventional trials assessing the effect of a glucose-lowering strategy on CV outcomes are limited. To provide some insight into these issues, we describe in this review the recent important data to understand the natural course of CV disease in diabetic individuals and the role of hyperglycemia at different times in the progression of HF.

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Talking to children about parental mental illness: The experiences of well parents

International Journal of Social Psychiatry ◽

10.1177/0020764018763687 ◽

2018 ◽

Vol 64 (4) ◽

pp. 367-373 ◽

Cited By ~ 3

Author(s):

Divya Ballal ◽

Janardhana Navaneetham

Keyword(s):

Mental Illness ◽

Interpretative Phenomenological Analysis ◽

Parental Mental Illness ◽

Sources Of Information ◽

Mental Health Systems ◽

The Family ◽

Supportive Family ◽

History Of ◽

Source Of Information

Background: Children of parents with mental illness are not routinely included in psychoeducational and supportive family interventions provided by adult mental health systems. The family, therefore, is an important and, sometimes, the only source of information and support for them. Aim: To understand the experiences of well parents in talking to their children about parental mental illness. Method: This article presents the findings of a qualitative study of the experiences of well parents in talking to their children about parental mental illness. Ten well parents whose spouses were diagnosed with a severe mental illness participated in the study. Socio-demographic information, family details and history of the spouse’s mental illness along with their experiences of talking to children about parental mental illness, the perceived risks and benefits, challenges they faced and the role of others in the process were recorded. Qualitative data were analysed using interpretative phenomenological analysis. Findings: The themes of ‘distancing children from parental mental illness’, ‘avoiding conversations about the illness’, ‘giving and receiving emotional support’, ‘providing explanations of the illness’ and ‘regulating other sources of information’ show the complex ways in which well parents influence their children’s understanding of parental mental illness. The findings are examined in the background of what is known about this topic from the perspective of children or of the parent with illness. Possible ways to support well parents in families affected by parental mental illness are discussed. Conclusion: This study is a step forward in the understanding of how families talk to children about parental mental illness and provides the perspective of the well parent.

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Adaptive convergent evolution of genome proofreading in SARS-CoV2: insights into the Eigen’s paradox

10.1101/2021.09.11.459886 ◽

2021 ◽

Author(s):

Keerthic Aswin ◽

Srinivasan Ramachandran ◽

Vivek T Natarajan

Keyword(s):

Convergent Evolution ◽

Genome Stability ◽

Evolutionary History ◽

Rna Binding ◽

Phylogenetic Analyses ◽

Comparative Genome Analysis ◽

The Family ◽

History Of ◽

Key Residues

AbstractEvolutionary history of coronaviruses holds the key to understand mutational behavior and prepare for possible future outbreaks. By performing comparative genome analysis of nidovirales that contain the family of coronaviruses, we traced the origin of proofreading, surprisingly to the eukaryotic antiviral component ZNFX1. This common recent ancestor contributes two zinc finger (ZnF) motifs that are unique to viral exonuclease, segregating them from DNA proof-readers. Phylogenetic analyses indicate that following acquisition, genomes of coronaviruses retained and further fine-tuned proofreading exonuclease, whereas related families harbor substitution of key residues in ZnF1 motif concomitant to a reduction in their genome sizes. Structural modelling followed by simulation suggests the role of ZnF in RNA binding. Key ZnF residues strongly coevolve with replicase, and the helicase involved in duplex RNA unwinding. Hence, fidelity of replication in coronaviruses is a result of convergent evolution, that enables maintenance of genome stability akin to cellular proofreading systems.

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Delinquency and the Pediatrician

Pediatrics in Review ◽

10.1542/pir.9.8.249 ◽

1988 ◽

Vol 9 (8) ◽

pp. 249-257

Author(s):

Alan D. Woolf

Keyword(s):

Risk Factors ◽

Health Assessment ◽

Health Problems ◽

Double Jeopardy ◽

Dental Pathology ◽

The Family ◽

Complete Health ◽

Clustering Of Risk Factors ◽

Hearing Difficulties

Adolescents may be predisposed to delinquency by a double-jeopardy situation of clustering of risk factors in physical health (eg, perinatal or nervous system trauma, naurodevelopmental or cognitive dysfunction, neglected health problems) and the environment (eg, poverty, disordered family dynamics, poor education). Pediatricians must be attentive to neglected or previously undiscovered health problems in this population, such as overlooked cosmetic or congential defects, nutritional problems, substance abuse, vision and hearing difficulties, dental pathology, and sex-related conditions and diseases. Delinquents, especially during the transition into detention, are at particular risk for injuries, depression, and suicidal behavior. The complete health assessment of the delinquent should include a neurodevelopmental, cognitive, and educational progress assessment. This will facilitate implementation of an appropriate individualized remediation program. The pediatrician, in the dual role of health care provider for the family and child advocate in the community, can accomplish much toward the primary, secondary, and tertiary prevention of delinquency.

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