PATHOLOGICAL STUDY OF BODY FLUIDS IN A TERTIARY CARE CENTER IN SOUTH INDIA.

2021 ◽  
pp. 60-61
Author(s):  
Earla Lakshmi Bai ◽  
Buddaiahgari Swathi ◽  
Siva Chaithanya Bangi
Keyword(s):  
Cell Count ◽  
Care Center ◽  
Tertiary Care ◽  
Clinical Pathology ◽  
Major Type ◽  
Pathology Laboratory ◽  
Female Ratio ◽  
Atypical Cells ◽  
A Prospective Study ◽  
Male To Female

Body cavities uid analysis is done routinely in both clinical pathology and cytology departments of Pathological laboratory. Any imbalance between uid 1. formation and removal leads to effusion, as stated by Starling's law The peritoneal, pleural, cerebrospinal and pericardial uids comprise the major chunk of 2 body uids . Accumulation of uid in various body cavities can occur in vast range of benign conditions and it also a frequent clinical presentation and complication of malignant disorder. METHODS: A prospective study was conducted in the Department of Pathology, Osmania general hospital Hyderabad, Telangana, India, during January 2020 to December 2020 and analyzed 880 uid samples collected from patients for cell count and cytology. The data collected was tabulated using Microsoft excel and analyzed using standard statistical tools. RESULTS -Of total 880 uids analyzed peritoneal uid (42%) constitutes the major type of uid sent frequently for analysis followed by cerebrospinal uid (41%) with male to female ratio of 1.9:1. 62.7% of uids had clear gross appearance . Of total 880 uid samples analyzed 649 samples (73.7%) had shown lymphocyte predominance. Of total 880 uids samples analyzed 9 samples (1%) were found positive for atypical cells, conrmed on cytology suggesting there malignant origin. CONCLUSION: uid aspiration from body cavities constitutes one of the common day care procedures for clinicians. Effusion uid analysis is key in delineating the background cause in the patient ranging from reactive, inammatory and malignant conditions. Fluid cell count coupled by cytological analysis of uids in pathology laboratory is a time tested tool having good sensitivity and specicity when interpreted along with biochemical parameters.

scholarly journals A study on clinical characteristics of herpes zoster in a tertiary care center

2017 ◽  
Vol 3 (1) ◽  
pp. 79
Author(s):  
Rachana R. ◽  
Shivaswamy K. N. ◽  
Anuradha H. V.
Keyword(s):  
Herpes Zoster ◽  
Clinical Characteristics ◽  
Care Center ◽  
Tertiary Care ◽  
Age Groups ◽  
Age Group ◽  
Female Ratio ◽  
Varicella Zoster ◽  
Medical College ◽  
Male To Female

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Herpes zoster (HZ), also known as shingles, derived from the Latin word Cingulum, for “girdle”. This is because a common presentation of HZ involves a unilateral rash that can wrap around the waist or torso like a girdle. HZ results due to reactivation of an earlier latent infection with the varicella zoster virus (VZV) in dorsal root ganglia. It occurs at all age groups, common over 60 years of age. It is estimated that in non-immune populations, approximately 15 cases per 1000 people occur per year. The objective of the study was to study the clinical characteristics in patients with uncomplicated herpes zoster.</span></p><p class="abstract"><strong>Methods:</strong> A total of 72 patients attending dermatology OPD at Ramaiah medical college between June 2013 to September 2014 were recruited after obtaining informed consent. A detailed history regarding onset of rash, pain, progression, duration and distribution of the lesions were recorded. Demographic information including age, sex, and any other co morbidities noted. Tzanck smear and serology for HIV was done where-ever necessary.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Of the 72 patients, females outnumbered males [M=35(48.61%), F=37 (51.39%)] with male to female ratio of 0.9 to 1. The mean age of presentation was 58±18 years. Majority of the patients (54%) were in the age group of 51 to 70 years followed by 31-50 years (25%). Least number of cases (9%) was in the age group of 21 to 30 years. Of the 72 subjects, thoracic involvement was noted in 30.6%, followed by lumbar (22%), and trigeminal (16%). Cervical (4%) and sacral (2%) involvement was the least. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Herpes zoster commonly occurs in old age and the presenting symptom being pain and burning sensation. Thoracic dermatome is the commonest site. Immunocompromised states like diabetes, malignancy and HIV can increase the risk of developing herpes zoster.</span></p>

scholarly journals A descriptive study of clinico-epidemiological profile of chronic urticaria from a tertiary care center

2021 ◽  
Vol 7 (2) ◽  
pp. 184
Author(s):  
Olasseri Kalathingal Reena Mariyath ◽  
Sreekanth Sukumarakurup ◽  
Sanjayan Rosamma Roopasree Pinky ◽  
Mohandas Ajina ◽  
Kollarukandy Vijayan Anagha
Keyword(s):  
Chronic Urticaria ◽  
House Dust ◽  
Care Center ◽  
Tertiary Care ◽  
Descriptive Study ◽  
Female Ratio ◽  
Medical College ◽  
Exact Etiology ◽  
Epidemiological Profile ◽  
Male To Female

<p><strong>Background:</strong> Chronic urticaria is defined as wheals occurring at least twice weekly for more than six weeks. Exact etiology of chronic urticaria is not known. Only a few studies are available about the clinical and epidemiological profile of chronic urticaria from our part of the country.</p><p><strong>Methods: </strong>A descriptive study was conducted among one hundred consecutives chronic urticaria patients attending the dermatology out patient department of government medical college, Kozhikode to find out the clinical and epidemiological profile of chronic urticaria.</p><p><strong>Results</strong>: Out of 100 patients 25 (25%) were males and 75 (75%) were females with a male to female ratio of 1:3. Angioedema was seen in 63 (63%) patients and dermographism in 53 (53%) patients. Food was the aggravating factor in 34 (34%) patients, exposure to house dust in 28 (28%), sweat in 36 (36%), pressure in 37 (37%), sunlight in 17 (17%), drugs in 22 (22%), stress in 36 (36%), heat in 13 (13%), water in 20 (20%), cold in 5 (5%), infection in 31 (31%) and infestations in 20 (20%) patients.</p><p><strong>Conclusions: </strong>Chronic urticaria is common in females. Angioedema and dermographism are seen in more than half of the patients with chronic urticaria. Most common aggravating factors of chronic urticaria were pressure, sweat, stress, food, infections and exposure to house dust.</p>

scholarly journals A study of cutaneous adverse drug reactions in the outpatient department of Dermatology at a tertiary care center in Gujarat, India

2017 ◽  
Vol 6 (5) ◽  
pp. 1115
Author(s):  
Dinesh A. Chavda ◽  
Satish D. Suthar ◽  
Shradhanand Singh ◽  
Jayesh D. Balat ◽  
Sailesh P. Parmar ◽  
...  
Keyword(s):  
Hospital Admissions ◽  
Care Center ◽  
Tertiary Care ◽  
Maculopapular Rash ◽  
Drug Reactions ◽  
Female Ratio ◽  
Drug Eruptions ◽  
Male Preponderance ◽  
Cutaneous Drug Reactions ◽  
A Prospective Study

Background: The data for adverse cutaneous drug reactions (ACDRs) is limited in Gujarat. The ACDRs are one of the frequent ADRs and cause of significant morbidity and mortality in patients of all areas of healthcare today. They are responsible for significant number of hospital admissions. Thus, the present study emphasises on the need and importance of an effective pharmacovigilance programme.Methods: A prospective study was undertaken in a 183 cases tertiary care teaching hospital of India. Male to female ratio, most common class of drug, individual drug causing ACDR, common types of ACDRs Parameters were studied. Other Parameters like Causality, preventability and severe or non-severe reactions were analyzed.Results: Majority of the patients (48%) with CADR belonged to the age group 25-44 followed by 45-64 (28%). Most frequent adverse cutaneous drug reactions reported were Urticaria (40%), Maculopapular rash (25%) & Fixed drug eruptions (21%) in decreasing order of frequency. Majority of reactions (96%) were Bizarre/Unpredictable in nature. As a group, antimicrobials (46%) were most frequently associated with CADR followed by NSAIDs (31%) and antiepileptics (11%).  Most of the reactions (93%) were mild-moderate and probable (77%) in nature. Approximately 60% of ACDRs reported in this study were preventable.Conclusions: There was slight male preponderance except acneiform eruptions. Cotrimoxazole being the most common offending drug then after Ibuprofen, Phenytoin among the anti-inflammatory, analgesics, antiepileptics class. Causality assessment resulted in high score 77% of probable category.

scholarly journals Nail changes in various dermatoses: an observational study conducted at tertiary care center, Ujjain, Madhya Pradesh, India

2020 ◽  
Vol 6 (2) ◽  
pp. 237
Author(s):  
Ujjwal Kumar ◽  
Krishnendra Varma ◽  
Ankur Shayalwar
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Disease Patient ◽  
Nail Plate ◽  
Exclusion Criteria ◽  
Common Pattern ◽  
Female Ratio ◽  
Lichen Striatus ◽  
Nail Changes ◽  
Male To Female

<p class="abstract"><strong>Background:</strong> Nail apparatus forms an integral part to be examined for all dermatological conditions. Nail changes are seen in various dermatosis like psoriasis, onychomycosis, lichen planus, collagen vascular disease, vesicobullous diseases and other papulosquamous diseases. Aims and objective of the study was to determine the prevalence of nail changes in various dermatological conditions.</p><p class="abstract"><strong>Methods:</strong> After applying inclusion and exclusion criteria, 269 cases with various nail changes were enrolled in the study. Detailed history and thorough nail examination was carried out along with other necessary investigations like CBC, RFT, LFT, nail clipping for fungal hyphae culture and microscopy.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 269 cases with nail disorders, male to female ratio was 1.5:1 and most common age group was 31-40 years. The most common abnormality observed was onychomycosis (34.2%) followed by nail changes in psoriasis (30.4%), LP (18.5%), eczema (4%), trachonychia (3.3%), paronychia (2.9%), lichen striatus (2.2%) and darier’s disease (0.37%). Among onychomycosis most common pattern observed was DLSO (82.6%) followed by PSO (7.6%), SWO (5.4%) and TDO (4.34%). The pattern of nail changes in psoriasis patients was pitting (30.4%), subungual hyperkeratosis (21.9%) and onycholysis (10.9%). Cases with LP had longitudinal striations (52%), thinning of nail plate and trachonychia (10% each). V shaped notching and distal splitting was seen in one of the Dariers’ disease patient.</p><p class="abstract"><strong>Conclusions:</strong> Nail changes form an indispensible part of various dermatological conditions. The pattern of involvement is unique in each and every disease. Hence examination of all the 20 nails should never be missed.</p>

scholarly journals The prevalence and pattern of pediatric dermatoses in a tertiary care center at Garhwal, Uttarakhand, India

2018 ◽  
Vol 6 (1) ◽  
pp. 56
Author(s):  
Ratan Singh ◽  
Varun Kumar Tiwari
Keyword(s):  
Skin Diseases ◽  
Fungal Infections ◽  
Pediatric Population ◽  
Acne Vulgaris ◽  
Care Center ◽  
Descriptive Analysis ◽  
Tertiary Care ◽  
Cross Sectional ◽  
Female Ratio ◽  
Male To Female

Background: Analysis of skin diseases in the pediatric population and its trends reflects the health and nutritional status of a community. This study aimed to evaluate the prevalence and pattern of skin diseases in children registered at the Dermatology OPD department of Hemawati Nandan Bahuguna Teaching Base Hospital, Srikot over a period of 1 year.Methods: A prospective cross-sectional descriptive analysis was conducted at the Dermatology OPD department of HNB teaching hospital to determine the pattern of dermatoses in children aged 0 days to 17 years, between 1 April 2017 and 31 March 2018. Cases with incomplete data, non-compliant to treatment and patients whose primary lesions are altered by the application of topical medication, not related to the existing disease were excluded from the study. The results were entered and tabulated in MS-excel sheet and descriptive analysis was done.Results: Out of 23,359 outpatients 6,274 (26.85%) were of a pediatric age with a male to female ratio of 1.2:1. The majority of the children belonged to young teens and teenagers (2377;37. 88%). Majority of pediatric dermatoses belonged to Infectious group (1373;21.88%) followed by Disorders of skin appendages (1087;17.33%) and Infestations (722;11.5%). The three most common diagnoses were Scabies (694;11.06%) followed by Fungal infections (568;10.43%) and Acne vulgaris (398;6. 34%).Conclusions: This study showed the current pattern of pediatric dermatoses in Garhwal region of Uttrakhand with a high frequency of infection and infestations with young teen and teenagers as the identified focus group for the need of intervention.

scholarly journals Lessons Learned From an Anatomic Pathology Department in a Large Academic Medical Center at the Epicenter of COVID-19

2021 ◽  
Vol 8 ◽  
pp. 237428952199424
Author(s):  
Tamar C. Brandler ◽  
Dana Warfield ◽  
Esther Adler ◽  
Aylin Simsir ◽  
Marie-Ange Exilhomme ◽  
...  
Keyword(s):  
Medical Center ◽  
Care Center ◽  
Academic Medical Center ◽  
Tertiary Care ◽  
Clinical Pathology ◽  
Fellowship Training ◽  
Lessons Learned ◽  
Pathology Laboratory ◽  
Pathology Department ◽  
Anatomic Pathology

Many state-wide, city-wide, and hospital-wide changes have been implemented due to the ongoing COVID-19 crisis. We describe lessons learned in an anatomic pathology division at a tertiary care center during the peak of the COVID-19 pandemic in the hopes that knowledge of our experiences can benefit other pathology departments as they encounter this pandemic. Five categories that are critical in strategic planning for the COVID-19 pandemic are discussed: workload, departmental policy revisions, impact on faculty, workforce staffing, and impact on educational programs, including residency and fellowship training. Although the volume of COVID-19 testing had grown placing increased demands on the clinical pathology laboratory, the volume of anatomic pathology cases had declined during the COVID-19 peak. Lessons learned were widespread including changes in the anatomic pathology workflow due to declining surgical and cytologic case volumes and increases in autopsy requests. Modifications were required in gross room policies, levels of personal protective equipment, and workforce. Travel and meeting policies were impacted. Adaptations to residency and fellowship programs were vast and included innovations in didactic and interactive education. We must learn from our experiences thus far in order to move forward, and we hope that our experiences in an anatomic pathology department in the epicenter of the COVID-19 pandemic can help other pathology departments across the country.

scholarly journals Serum Concentration of Myelin Basic Protein as a Prognostic Marker in Mild-to-moderate Head Injury Patients: A Prospective Study in a Tertiary Care Center

2021 ◽  
Author(s):  
Ashvamedh Singh ◽  
Kulwant Singh ◽  
Anurag Sahu ◽  
R. S. Prasad ◽  
N. Pandey ◽  
...  
Keyword(s):  
Head Injury ◽  
Prospective Study ◽  
Myelin Basic Protein ◽  
Prognostic Marker ◽  
Outcome Prediction ◽  
Basic Protein ◽  
Care Center ◽  
Tertiary Care ◽  
Gcs Score ◽  
A Prospective Study

Abstract Objective To estimate the level of myelin basic protein (MBP) and look for its validity in outcome prediction among mild-to-moderate head injury patients. Materials and Methods It was a prospective study done at the Department of Neurosurgery, Institute of Medical Sciences, Banaras Hindu University from Jan 2018 to July 2019. All patients who presented to us within 48 hours of injury with mild-to-moderate head injury with apparently normal CT brain were include in the study. The serum sample were collected on the day of admission and 48 hours later, and patients were treated with standard protocols and observed 6 months postdischarge. Results Of the 32 patients enrolled, we observed mean MBP level was higher for severity of brain damage, but not associated with age, mode of injury, and radiological diagnosis. Mean MBP levels were not statistically associated with Glasgow coma scale (GCS) score at admission but was correlated to outcome with p < 0.05, with sensitivity of 50% and specificity 72%, that is, patients with good outcome have lower mean MBP levels. Conclusion MBP as per our analysis can be used as a prognostic marker in patients with head injury. It is not the absolute value rather a trend showing rise in serum MBP levels, which carries a significant value in outcome prediction.

scholarly journals TO STUDY THE PREVALENCE AND CLINICAL PROFILE OF CHRONIC ATRIAL FIBRILLATION IN HOSPITALIZED PATIENTS

2014 ◽  
Vol 04 (02) ◽  
pp. 017-020
Author(s):  
Dharma Rao V. ◽  
Rajaneesh Reddy M. ◽  
Srikanth K. ◽  
Raj Kumar Prakash B. ◽  
Satya Prasad A. ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Heart Disease ◽  
Care Center ◽  
Tertiary Care ◽  
Chronic Atrial Fibrillation ◽  
Hospitalized Patients ◽  
Clinical Profile ◽  
Female Dominance ◽  
Elderly Age ◽  
Female Ratio

Abstract: Objective: To determine the prevalence of chronic atrial fibrillation (AF) in a tertiary care center and to identify the clinical profile of chronic AF in hospitalized patients. Methods: All patients admitted to Mamata General Hospital in medicine/cardiology wards with chronic AF (persistent and permanent) during the period January 2012 to December 2012 were included into the study. The principal exclusion criteria were new onset AF and acute AF. Results: During the study period, 49 patients were admitted with chronic AF with an average of 45.44 years. A slight female dominance was seen with male: female ratio of 1:1.2. Half of the patients (51%) were below the age 50 years. The elderly age group comprised of only 16.3% of cases. The commonest presenting complaint was dyspnea followed by palpitation. Rheumatic valvular heart disease was seen more commonly in people below the age of 50 years whereas hypertension and ischemic heart disease after 50 years. Heart failure was the commonest condition associated with the chronic AF and was the cause of hospitalization in almost fifty percent of cases Conclusion: Chronic AF is still a cause of concern in India in people below the age of 50 years due to high prevalence of rheumatic fever inspite of advances in the medical field.

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