Nail changes in various dermatoses: an observational study conducted at tertiary care center, Ujjain, Madhya Pradesh, India

Background: Nail apparatus forms an integral part to be examined for all dermatological conditions. Nail changes are seen in various dermatosis like psoriasis, onychomycosis, lichen planus, collagen vascular disease, vesicobullous diseases and other papulosquamous diseases. Aims and objective of the study was to determine the prevalence of nail changes in various dermatological conditions.Methods: After applying inclusion and exclusion criteria, 269 cases with various nail changes were enrolled in the study. Detailed history and thorough nail examination was carried out along with other necessary investigations like CBC, RFT, LFT, nail clipping for fungal hyphae culture and microscopy.Results: Out of 269 cases with nail disorders, male to female ratio was 1.5:1 and most common age group was 31-40 years. The most common abnormality observed was onychomycosis (34.2%) followed by nail changes in psoriasis (30.4%), LP (18.5%), eczema (4%), trachonychia (3.3%), paronychia (2.9%), lichen striatus (2.2%) and darier’s disease (0.37%). Among onychomycosis most common pattern observed was DLSO (82.6%) followed by PSO (7.6%), SWO (5.4%) and TDO (4.34%). The pattern of nail changes in psoriasis patients was pitting (30.4%), subungual hyperkeratosis (21.9%) and onycholysis (10.9%). Cases with LP had longitudinal striations (52%), thinning of nail plate and trachonychia (10% each). V shaped notching and distal splitting was seen in one of the Dariers’ disease patient.Conclusions: Nail changes form an indispensible part of various dermatological conditions. The pattern of involvement is unique in each and every disease. Hence examination of all the 20 nails should never be missed.

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A study on clinical characteristics of herpes zoster in a tertiary care center

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20170081 ◽

2017 ◽

Vol 3 (1) ◽

pp. 79

Author(s):

Rachana R. ◽

Shivaswamy K. N. ◽

Anuradha H. V.

Keyword(s):

Herpes Zoster ◽

Clinical Characteristics ◽

Care Center ◽

Tertiary Care ◽

Age Groups ◽

Age Group ◽

Female Ratio ◽

Varicella Zoster ◽

Medical College ◽

Male To Female

Background: Herpes zoster (HZ), also known as shingles, derived from the Latin word Cingulum, for “girdle”. This is because a common presentation of HZ involves a unilateral rash that can wrap around the waist or torso like a girdle. HZ results due to reactivation of an earlier latent infection with the varicella zoster virus (VZV) in dorsal root ganglia. It occurs at all age groups, common over 60 years of age. It is estimated that in non-immune populations, approximately 15 cases per 1000 people occur per year. The objective of the study was to study the clinical characteristics in patients with uncomplicated herpes zoster.Methods: A total of 72 patients attending dermatology OPD at Ramaiah medical college between June 2013 to September 2014 were recruited after obtaining informed consent. A detailed history regarding onset of rash, pain, progression, duration and distribution of the lesions were recorded. Demographic information including age, sex, and any other co morbidities noted. Tzanck smear and serology for HIV was done where-ever necessary.Results: Of the 72 patients, females outnumbered males [M=35(48.61%), F=37 (51.39%)] with male to female ratio of 0.9 to 1. The mean age of presentation was 58±18 years. Majority of the patients (54%) were in the age group of 51 to 70 years followed by 31-50 years (25%). Least number of cases (9%) was in the age group of 21 to 30 years. Of the 72 subjects, thoracic involvement was noted in 30.6%, followed by lumbar (22%), and trigeminal (16%). Cervical (4%) and sacral (2%) involvement was the least. Conclusions: Herpes zoster commonly occurs in old age and the presenting symptom being pain and burning sensation. Thoracic dermatome is the commonest site. Immunocompromised states like diabetes, malignancy and HIV can increase the risk of developing herpes zoster.

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A descriptive study of clinico-epidemiological profile of chronic urticaria from a tertiary care center

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20210075 ◽

2021 ◽

Vol 7 (2) ◽

pp. 184

Author(s):

Olasseri Kalathingal Reena Mariyath ◽

Sreekanth Sukumarakurup ◽

Sanjayan Rosamma Roopasree Pinky ◽

Mohandas Ajina ◽

Kollarukandy Vijayan Anagha

Keyword(s):

Chronic Urticaria ◽

House Dust ◽

Care Center ◽

Tertiary Care ◽

Descriptive Study ◽

Female Ratio ◽

Medical College ◽

Exact Etiology ◽

Epidemiological Profile ◽

Male To Female

Background: Chronic urticaria is defined as wheals occurring at least twice weekly for more than six weeks. Exact etiology of chronic urticaria is not known. Only a few studies are available about the clinical and epidemiological profile of chronic urticaria from our part of the country.Methods: A descriptive study was conducted among one hundred consecutives chronic urticaria patients attending the dermatology out patient department of government medical college, Kozhikode to find out the clinical and epidemiological profile of chronic urticaria.Results: Out of 100 patients 25 (25%) were males and 75 (75%) were females with a male to female ratio of 1:3. Angioedema was seen in 63 (63%) patients and dermographism in 53 (53%) patients. Food was the aggravating factor in 34 (34%) patients, exposure to house dust in 28 (28%), sweat in 36 (36%), pressure in 37 (37%), sunlight in 17 (17%), drugs in 22 (22%), stress in 36 (36%), heat in 13 (13%), water in 20 (20%), cold in 5 (5%), infection in 31 (31%) and infestations in 20 (20%) patients.Conclusions: Chronic urticaria is common in females. Angioedema and dermographism are seen in more than half of the patients with chronic urticaria. Most common aggravating factors of chronic urticaria were pressure, sweat, stress, food, infections and exposure to house dust.

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PATHOLOGICAL STUDY OF BODY FLUIDS IN A TERTIARY CARE CENTER IN SOUTH INDIA.

10.36106/ijsr/5701996 ◽

2021 ◽

pp. 60-61

Author(s):

Earla Lakshmi Bai ◽

Buddaiahgari Swathi ◽

Siva Chaithanya Bangi

Keyword(s):

Cell Count ◽

Care Center ◽

Tertiary Care ◽

Clinical Pathology ◽

Major Type ◽

Pathology Laboratory ◽

Female Ratio ◽

Atypical Cells ◽

A Prospective Study ◽

Male To Female

Body cavities uid analysis is done routinely in both clinical pathology and cytology departments of Pathological laboratory. Any imbalance between uid 1. formation and removal leads to effusion, as stated by Starling's law The peritoneal, pleural, cerebrospinal and pericardial uids comprise the major chunk of 2 body uids . Accumulation of uid in various body cavities can occur in vast range of benign conditions and it also a frequent clinical presentation and complication of malignant disorder. METHODS: A prospective study was conducted in the Department of Pathology, Osmania general hospital Hyderabad, Telangana, India, during January 2020 to December 2020 and analyzed 880 uid samples collected from patients for cell count and cytology. The data collected was tabulated using Microsoft excel and analyzed using standard statistical tools. RESULTS -Of total 880 uids analyzed peritoneal uid (42%) constitutes the major type of uid sent frequently for analysis followed by cerebrospinal uid (41%) with male to female ratio of 1.9:1. 62.7% of uids had clear gross appearance . Of total 880 uid samples analyzed 649 samples (73.7%) had shown lymphocyte predominance. Of total 880 uids samples analyzed 9 samples (1%) were found positive for atypical cells, conrmed on cytology suggesting there malignant origin. CONCLUSION: uid aspiration from body cavities constitutes one of the common day care procedures for clinicians. Effusion uid analysis is key in delineating the background cause in the patient ranging from reactive, inammatory and malignant conditions. Fluid cell count coupled by cytological analysis of uids in pathology laboratory is a time tested tool having good sensitivity and specicity when interpreted along with biochemical parameters.

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The prevalence and pattern of pediatric dermatoses in a tertiary care center at Garhwal, Uttarakhand, India

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20185002 ◽

2018 ◽

Vol 6 (1) ◽

pp. 56

Author(s):

Ratan Singh ◽

Varun Kumar Tiwari

Keyword(s):

Skin Diseases ◽

Fungal Infections ◽

Pediatric Population ◽

Acne Vulgaris ◽

Care Center ◽

Descriptive Analysis ◽

Tertiary Care ◽

Cross Sectional ◽

Female Ratio ◽

Male To Female

Background: Analysis of skin diseases in the pediatric population and its trends reflects the health and nutritional status of a community. This study aimed to evaluate the prevalence and pattern of skin diseases in children registered at the Dermatology OPD department of Hemawati Nandan Bahuguna Teaching Base Hospital, Srikot over a period of 1 year.Methods: A prospective cross-sectional descriptive analysis was conducted at the Dermatology OPD department of HNB teaching hospital to determine the pattern of dermatoses in children aged 0 days to 17 years, between 1 April 2017 and 31 March 2018. Cases with incomplete data, non-compliant to treatment and patients whose primary lesions are altered by the application of topical medication, not related to the existing disease were excluded from the study. The results were entered and tabulated in MS-excel sheet and descriptive analysis was done.Results: Out of 23,359 outpatients 6,274 (26.85%) were of a pediatric age with a male to female ratio of 1.2:1. The majority of the children belonged to young teens and teenagers (2377;37. 88%). Majority of pediatric dermatoses belonged to Infectious group (1373;21.88%) followed by Disorders of skin appendages (1087;17.33%) and Infestations (722;11.5%). The three most common diagnoses were Scabies (694;11.06%) followed by Fungal infections (568;10.43%) and Acne vulgaris (398;6. 34%).Conclusions: This study showed the current pattern of pediatric dermatoses in Garhwal region of Uttrakhand with a high frequency of infection and infestations with young teen and teenagers as the identified focus group for the need of intervention.

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TO STUDY THE PREVALENCE AND CLINICAL PROFILE OF CHRONIC ATRIAL FIBRILLATION IN HOSPITALIZED PATIENTS

Journal of Health and Allied Sciences NU ◽

10.1055/s-0040-1703758 ◽

2014 ◽

Vol 04 (02) ◽

pp. 017-020

Author(s):

Dharma Rao V. ◽

Rajaneesh Reddy M. ◽

Srikanth K. ◽

Raj Kumar Prakash B. ◽

Satya Prasad A. ◽

...

Keyword(s):

Atrial Fibrillation ◽

Heart Disease ◽

Care Center ◽

Tertiary Care ◽

Chronic Atrial Fibrillation ◽

Hospitalized Patients ◽

Clinical Profile ◽

Female Dominance ◽

Elderly Age ◽

Female Ratio

Abstract: Objective: To determine the prevalence of chronic atrial fibrillation (AF) in a tertiary care center and to identify the clinical profile of chronic AF in hospitalized patients. Methods: All patients admitted to Mamata General Hospital in medicine/cardiology wards with chronic AF (persistent and permanent) during the period January 2012 to December 2012 were included into the study. The principal exclusion criteria were new onset AF and acute AF. Results: During the study period, 49 patients were admitted with chronic AF with an average of 45.44 years. A slight female dominance was seen with male: female ratio of 1:1.2. Half of the patients (51%) were below the age 50 years. The elderly age group comprised of only 16.3% of cases. The commonest presenting complaint was dyspnea followed by palpitation. Rheumatic valvular heart disease was seen more commonly in people below the age of 50 years whereas hypertension and ischemic heart disease after 50 years. Heart failure was the commonest condition associated with the chronic AF and was the cause of hospitalization in almost fifty percent of cases Conclusion: Chronic AF is still a cause of concern in India in people below the age of 50 years due to high prevalence of rheumatic fever inspite of advances in the medical field.

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COMPARISON OF CLINICO-SOCIAL PROFILE OF PULMONARY AND EXTRA PULMONARY TUBERCULOSIS IN TERTIARY CARE HOSPITAL IN A RURALAREA: A RETROSPECTIVE STUDY

10.36106/ijsr/4605295 ◽

2021 ◽

pp. 70-72

Author(s):

Gaurav Santosh Nemade ◽

Sumit Nitin Dhus ◽

Arushi Ramesh Shetty ◽

Neha Dhananjay Firake

Keyword(s):

Tertiary Care ◽

Care Hospital ◽

Female Ratio ◽

Extra Pulmonary Tuberculosis ◽

Younger Age ◽

Tobacco Addiction ◽

History Of ◽

Early Case ◽

Male To Female ◽

Clinical Characteristic

BACKGROUND AND OBJECTIVES: The burden of tuberculosis (TB) in India is the highest accounting for 26% of the global incidence. A total of 1.4 million people died from TB in 2019 (including 208 000 people with HIV). India accounts for a fourth of the global burden of TB and 29% of global mortality. Therefore, we carried out this study to compare demographic, lifestyle and clinical characteristic between pulmonary TB (PTB) and extrapulmonary TB (EPTB). MATERIALS AND METHODOLOGY:Aretrospective analysis was carried of 348 patients diagnosed in DOTS centre, Pravara Rural Hospital, Loni. Characteristics of demographic and clinical characteristics were obtained from medical case records. RESULTS:Among the 348 cases, 71.3% were PTB and 28.7% were EPTB including, pleural (36%), meningeal (27%) and lymphatic (20%) cases. The male to female ratio in PTB and EPTB are 1.99 and 1.22 respectively. EPTB was more common at younger age (<25 years). Tobacco addiction (10.9%), diabetes mellitus (4.03%), HIV positivity (12.1%) and history of contact with Tb patients (17.7%) were more likely to be associated with PTB. CONCLUSION:Increased awareness of the risk factors may facilitate early case nding and better management outcomes for these patients.

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GASTRIC CANCER: A 5 YEAR RETROSPECTIVE ANALYSIS OF CLINICAL, PATHOLOGICAL AND TREATMENT ASPECTS FROM A TERTIARY CARE CENTER IN SOUTH INDIA.

10.36106/gjra/0711411 ◽

2021 ◽

pp. 129-132

Author(s):

B. Ramkumar ◽

J. Kannan ◽

Ingersal. N ◽

Srigopal mohanty ◽

Amit saklani ◽

...

Keyword(s):

Risk Factors ◽

Gastric Cancer ◽

South India ◽

Care Center ◽

Tertiary Care ◽

Tumor Location ◽

Advanced Stage ◽

Tertiary Care Center ◽

Nodal Disease ◽

Female Ratio

Context: Gastric cancer(GC) is fth most common cancer worldwide. Mostly presents with advanced stage and poor overall survival. Methods: Retrospective study on clinical, pathological, pattern of distant metastasis(DM) , treatment aspect of GC treated between January 2014 to December 2018 in a tertiary care center in south India. Statistical analysis : Chi square test and multivariate analysis (MVA) were used for analysis. P <0.05 was considered signicant. Results: Median age at diagnosis is 57 years. Higher male : female ratio. Most common presentation was abdominal pain followed vomiting. Malignant Gastric outlet obstruction(MGOO) was present in 22.7%. Histologically , all patients had adenocarcinoma with predominantly moderate differentiation (51.1%). Liver (19.1%)was most common site of metastasis . Curative surgery was done in 35.5% of patients. D2 lymph node dissection was performed in 12.4% of patient. Patients were given perioperative /preoperative/ adjuvant / palliative chemotherapy. MVA revealed history of tobacco use, body of stomach tumor location, nodal disease were risk factors for DM. Conclusion : The present analysis revealed use of tobacco, alcohol intake were main risk factors for GC. Most of the patients present in advanced stage , so prevention by avoiding risk factors and early detection by signs , symptoms and endoscopy are necessary. Use of tobacco,site of tumor location, nodal disease were factors associated with DM. Aggressive management with both surgery and chemotherapy is warranted for locally advanced disease.

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Accidental childhood poisoning in Paediatrics department of a tertiary care facility: A retrospective review

Nigerian Journal of Paediatrics ◽

10.4314/njp.v47i3.4 ◽

2020 ◽

Vol 47 (3) ◽

Author(s):

D.C. Obu ◽

M.C. Orji ◽

U.V. Muoneke ◽

U.V. Asiegbu ◽

G.O. Ezegbe

Keyword(s):

Tertiary Care ◽

Care Facility ◽

Accidental Poisoning ◽

Female Ratio ◽

The Public ◽

Tertiary Care Facility ◽

Childhood Poisoning ◽

The Mean ◽

The Relationship ◽

Male To Female

Background: Accidental childhood poisoning is a recognized preventable cause of morbidity and mortality among children worldwide. This studywas aimed at determining the prevalence, pattern, and outcome of childhood poisoning among children in Abakaliki, Ebonyi State. Material and Methods: Medical records of all cases of accidental childhood poisoning admitted into Children’s emergency room (CHER) of the health facility of study between January 2014 and December 2018 were retrospectively identified and relevant data extracted and analyzed usingSPSS version 22. Results: Out of the 7,700 children that presented to CHER over a 5- year period, 42 were cases of poisoning, giving prevalence rate of 0.5%. Of the 42 cases, only 20 case notes were retrieved. The male to female ratio was 2.3:1 while the ages ranged between 6months and 14 years with the mean age of 3.06±2.88. Kerosene poisoning had the highest proportion of 50.0% (10/20) with the overall mortality rate of 5.0% (1/20).The relationship between age, place of residence and outcome in poisoned children was statistically significant (p = 0.038, 0.045 respectively). Conclusion: Accidental childhood poisoning is common in Abakaliki. Kerosene still remained the major agent while male toddlers were most vulnerable. There is need to intensify enlightenment campaigns and education of the public about the hazard of improper storage of kerosene and other implicated substances at home. Keywords: Accidental poisoning, Childhood, Kerosene

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Clinical and laboratory profiles of genital ulcers (sexually transmitted diseases) in a tertiary care center in northeastern India

Our Dermatology Online ◽

10.7241/ourd.20212.4 ◽

2021 ◽

Vol 12 (2) ◽

pp. 120-129

Author(s):

Romita Bachaspatimayum ◽

Zamzachin Guite ◽

Thangjam Bijayanti Devi

Keyword(s):

Care Center ◽

Tertiary Care ◽

Herpes Genitalis ◽

Tertiary Care Center ◽

Cross Sectional ◽

Female Ratio ◽

Ulcer Disease ◽

Sexually Transmitted ◽

Northeastern India ◽

Genital Ulcers

Background: Genital ulcers are defined as breaches in the continuity of the genital mucosa and/or skin. Sexually transmitted infections (STIs) that cause genital ulcer disease (GUD) are syphilis, chancroid, donovanosis, lymphogranuloma venereum (LGV), and herpes genitalis. This study aimed to investigate the clinical and laboratory profiles of STI-related genital ulcers. Materials and Methods: A cross-sectional two-year study was conducted on patients attending the Outpatient Department of Dermatology, Venereology and Leprosy in a tertiary care center in northeastern India. Selected were 95 patients who presented themselves with STI-related genital ulcers. Detailed history taking and examination were conducted with basic tests to assist the diagnosis. Results: The male-to-female ratio was 3.32:1, and the most common site was the glans and prepuce in males (28.77%) and the labia majora and minora in females (36.36%). 96.84% of patients had superficial ulcers. The KOH mount was positive in 26 patients. The Tzanck smear was positive in 31 patients. RPR was positive in four. HIV was positive in eleven. Herpes genitalis (96.84%) was the most common GUD. Mixed STIs were attested in 41.05% of patients. Conclusion: GUD can take various forms of presentation. The available laboratory tests should be utilized. The possibility of mixed infections should always be kept in mind.

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Descriptive study of clinical profile and outcome in patients of acute on chronic liver failure, at a tertiary care center in Northern India

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20204521 ◽

2020 ◽

Vol 7 (11) ◽

pp. 1687

Author(s):

Rakesh Kumar ◽

Vandana Rana ◽

Varghese Koshy ◽

Vandana Gangadharan ◽

George Koshy

Keyword(s):

Liver Failure ◽

Care Center ◽

Tertiary Care ◽

Descriptive Study ◽

Chronic Liver ◽

Clinical Profile ◽

Chronic Liver Failure ◽

Tertiary Care Centre ◽

Female Ratio ◽

Common Cause

Background: Acute-on-chronic liver failure (ACLF) is a recently described syndrome that is characterized by abrupt deterioration in patients with chronic liver disease (CLD) and has high short-term mortality. The aim of this study was to describe the clinical profile, causes and outcomes of ACLF at a tertiary care centre in Northern India.Methods: In this descriptive study of 50 consecutive patients, were included, between August 2015 to January 2018, who were admitted and diagnosed as ACLF as defined by APASL. Causes of acute precipitating event and CLD and outcomes were assessed.Occurrence and severity of organ failure was also assessed.Results: 48 (96 %) were males and 2 (4%) were females with male to female ratio was 24:1. The mean age of male and female subjects was similar, 40.7±9.9 years and 39.2±9.4 years respectively. The most common cause of CLD was alcohol in 50% cases and next most common cause was hepato-tropic viruses HBV infection in 20%, HCV in 6% cases and there was unknown cause in 12 % cases. The most common precipitating factor of acute decompensation was alcohol in 50% cases, hepatotropic viruses in 30% cases. Excluded sepsis and GI bleed as precipitating events. The combined mortality at the end of 1-month and 3-months, in our study was 60%. CLIF-SOFA score was found to be the most reliable scoring system to discriminate between survivors and non survivors. Conclusions: Alcohol was the commonest precipitating cause of ACLF. Organ failures (OFs) are independently predictive of mortality.

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