scholarly journals The effectiveness of the treatment of sleep disturbances in anxiety-depressive disorders of neurotic and organic genesis

2021 ◽  
pp. 43-47
Author(s):  
Yuliia Liashchenko ◽  
Liudmyla Yuryeva
Keyword(s):  
Sleep Disturbance ◽  
Sleep Disorders ◽  
Medical Practice ◽  
Sleep Disturbances ◽  
Depressive Disorders ◽  
Combined Treatment ◽  
Underlying Disease ◽  
Severity Scale ◽  
General Medical Practice ◽  
Insomnia Severity

Sleep disturbance is one of the most frequent complaints of patients in general medical practice. The highest comorbidity of dysomnias was observed with anxiety and anxiety-depressive disorders. A bi-directional relationship has been found, suggesting that sleep disorders and anxiety-depressive disorders may aggravate each other, complicate treatment and provoke a relapse. The aim of this study was to evaluate the efficacy of the treatment of sleep disorders in patients with neurotic and organic anxiety-depressive disorders. In order to reach this goal 120 patients with anxiety-depressive disorders with sleep disorders (60 patients with disorders of neurotic genesis and 60 — with isorders of organic genesis), who were divided into 4 groups according to the genesis of the disorder and the treatment regimen, were studied. The evaluation of the dynamics of sleep disturbance correction was carried out using clinical and psychopathological methods supplemented by the Insomnia Severity Scale (Morin Ch. M.), descriptive and analytical statistical methods. It was found that combined treatment (psychopharmacotherapy and psychotherapy) of sleep disorders in patients with anxiety-depressive disorders of neurotic and organic genesis was more effective compared to patients who received only pharmacological treatment aimed at the correction of the underlying disease.

scholarly journals The Association of Unreported Sleep Disturbances and Systemic Inflammation: Findings from the 2005-2008 NHANES

2018 ◽  
Vol 2018 ◽  
pp. 1-8
Author(s):  
Jeff A. Dennis ◽  
Ahmad Alazzeh ◽  
Ann Marie Kumfer ◽  
Rebecca McDonald-Thomas ◽  
Alan N. Peiris
Keyword(s):  
Sleep Apnea ◽  
Sleep Disturbance ◽  
Sleep Disorders ◽  
Sleep Disorder ◽  
Inflammatory Markers ◽  
Sleep Disturbances ◽  
Laboratory Data ◽  
Poor Sleep ◽  
Distribution Width ◽  
Inflammatory Status

Background/Objective. Sleep apnea is associated with elevated inflammatory markers. A subgroup of patients never report sleep disturbances to their physician. The inflammatory status of this subgroup is not known. The present study aims to evaluate two inflammatory markers, C-reactive protein (CRP) and red cell distribution width (RDW), in those with unreported sleep disturbances and compares these findings to those with and without reported sleep disorders. We also investigate the utility of RDW as an inflammatory marker in sleep disorders. Methods. Sample includes 9,901 noninstitutionalized, civilian, nonpregnant adults from the 2005-2008 National Health and Nutrition Examination Survey, a nationally representative, cross-sectional U.S. study. Sleep questionnaire and laboratory data were used to compare inflammatory markers (CRP and RDW) in five subgroups of individuals: reporting physician-diagnosed sleep apnea, reporting another physician-diagnosed sleep disorder, reported sleep disturbance to physician with no resulting diagnosis, unreported sleep disturbance (poor sleep quality not reported to physician), and no diagnosed sleep disorder or sleep disturbance. Results. Individuals with unreported sleep disturbance had significantly higher odds of elevated RDW (>13.6%) when compared to those without a sleep disturbance in adjusted models (OR=1.33). Those with unreported sleep disturbance had significantly higher odds of elevated CRP levels (>1 mg/L) than those without sleep disturbances (OR 1.34), although the association was not significant when adjusted for obesity and other controls. Conclusion. Self-identified unreported sleep disturbances are associated with significantly higher odds of elevated RDW than those without sleep disturbances. RDW may serve as a valuable indicator in identifying individuals at higher risk for sleep apnea and other sleep disorders.

scholarly journals Evaluation of Subjective Sleep Disturbances in Cancer Patients: A Cross-Sectional Study in a Radiotherapy Department

2021 ◽  
Vol 12 ◽  
Author(s):  
Jun Wang ◽  
Bei-Yun Zhou ◽  
Chen-Lu Lian ◽  
Ping Zhou ◽  
Hui-Juan Lin ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Sleep Quality ◽  
Sleep Disturbance ◽  
Sleep Disorders ◽  
Cancer Patients ◽  
Sleep Disturbances ◽  
Cancer Type ◽  
Multivariate Logistic Regression ◽  
Subjective Sleep ◽  
Radiotherapy Department

Background: The factors associated with sleep disturbances in cancer patients remains unclear. This study aimed to explore the prevalence of sleep disorders and predictors associated with sleep disturbance in cancer patients from a radiotherapy department.Methods: Patients with cancers were recruited before the start of radiotherapy from our institution between January 2019 and February 2020. Pittsburgh Sleep Quality Index (PSQI) scale was used to assess sleep quality. Descriptive statistics, Chi-square test, and multivariate logistic regression analysis were used to conduct statistical analysis.Results: A total of 330 eligible patients were included. Of them, 38.3% (n = 127) had the globe PSQI score >7, indicating that they suffered from sleep disorders. Patients with lung cancer (45.2%) were more likely to suffer from sleep disturbance, followed by cervical cancer (43.8%), nasopharyngeal carcinoma (41.7%), esophageal cancer (41.5%), breast cancer (37.7%), and colorectal cancer (30%). With regard to the PSQI components, the mean sleep duration was 8 h, 20.3% (n = 67) of them reported poor subjective sleep quality, 6.1% (n = 20) needed medication to improve sleep, and 53.6% (n = 177) suffered daytime dysfunction. Multivariate logistic regression models showed body mass index (BMI) ≥ 20 kg/m2 [odds ratio (OR) 0.599, 95% confidence interval (CI) 0.329–0.948, P = 0.031] and the receipt of surgery (OR 0.507, 95% CI 0.258–0.996, P = 0.048) were the significant favorable predictors for sleep disturbance, while age, gender, marital status, education level, comorbidity, metastasis status, diagnostic status, and cancer type were not significantly associated with sleep disturbance.Conclusions: Approximately 40% of the cancer patients suffer from sleep disturbance before the start of radiotherapy. Patients with BMI ≥ 20 kg/m2 and receiving surgery are less likely to develop sleep disturbance in comparison with others.

ANXIETY AND DEPRESSIVE DISORDERS IN GENERAL MEDICAL PRACTICE: TOPICAL ISSUES AND UNSOLVED PROBLEMS

2021 ◽  
pp. 14-22
Author(s):  
A. A. Kirpichenka ◽  
Keyword(s):  
General Practitioners ◽  
Medical Practice ◽  
Depressive Disorders ◽  
Psychiatric Care ◽  
Modern Medicine ◽  
General Medical Practice ◽  
Foreign Countries ◽  
The Republic ◽  
Somatic Diseases ◽  
Quality Diagnosis

Diagnosis of anxiety and depressive disorders in general medical practice is a very important problem of modern medicine. This review article provides basic information about the epidemiology and economic burden of anxiety-depressive disorders, their comorbidity with other mental and somatic diseases, and the connection with suicidal behavior. According to the Decree of the Ministry of Health of the Republic of Belarus dated 02.03.2020 № 13 «On approval of the clinical protocol» «Diagnosis and treatment of patients with mental and behavioral disorders by general practitioners», this article focuses on depression, generalized anxiety, panic, mixed anxiety and depressive disorder in general medical practice. Relevant issues of low quality diagnosis of anxiety and depressive disorders are identified, which are associated both with the complexity of the clinical picture of the diseases in question and with organizational problems. Particular attention is also paid to the need for further integration of psychiatric care into general medical practice while increasing its accessibility and quality. For this, it is necessary to continue studying the best practices of foreign countries in which family and general practitioners have been providing psychiatric care to patients for many years.

scholarly journals Features of dyssomnyas in primary episode of bipolar affective disorder

2019 ◽  
Vol 23 (3) ◽  
pp. 393-396
Author(s):  
Yu.I. Mysula ◽  
O.P. Wenger
Keyword(s):  
Sleep Disturbance ◽  
Sleep Disorders ◽  
Affective Disorder ◽  
Sleep Disturbances ◽  
Bipolar Affective Disorder ◽  
The Other ◽  
Men And Women ◽  
Falling Asleep ◽  
Wide Range ◽  
Mixed Variant

Bipolar affective disorder (BAD) is one of the actual problems in modern psychiatry. The aim of the study is to investigate dyssomnia in patients with primary episode of BAD, taking into account, the sex and clinical features of the diseases debut. We have clinically examined 65 men and 88 women diagnosed with bipolar affective disorder in the period 2015–2019. It was found that dyssomnia is present in 98.3% of all patients, in 97.7% of men and in 98.7% of women with depressive variant of the primary episode of BAD, accordingly in 30.4%, 26.7% and 37.5% of patients with manic variant and at 100,0% of patients with mixed variant. The structure of sleep disorders varies significantly depending on the variant of the primary episode: with depressive, prevail night and early awakenings (100.0%), sleep disturbance (75.6%, 70.5%, and 78.7%), unstable sleep (47.9%, 59.1% and 41.3%, p<0.05), nightmares (12.6%, 13.6% and 12.0%); at manic — unstable sleep (73.9%, 73.3% and 75.0%), sleep disturbance (17.4%, 13.3% and 25.0%) and frequent night awakenings (13.0%, 13.3% and 12.0%), in the mixed variant — falling asleep (72.7%, 66.7% and 80.0%), unstable sleep (72.7%, 83.3% and 60.0%), frequent night awakenings (54.5%, 66.7%, and 40.0%), early awakening (36.4%, 50.0%, and 20.0%) and nightmares (27.3%, 16.7% and 40.0%). Thus, the primary episode of bipolar affective disorder is accompanied by a wide range of dyssomnias, among which the leading are disorders of depth and stability of sleep. Manifestations of dyssomnia vary depending on the clinical type of the primary episode of BAD: with the depressive variant, prevail night awakenings, early awakenings and sleep disturbances, with unstable sleep, and with mixed sleep disturbance and unstable sleep. Dyssomnia prevalence is highest for mixed and lowest for manic variants. In depressive men, unstable sleep was more common, and the other disorders of sleep in men and women were not significantly different.

scholarly journals Sleep disturbances and related occupational diseases in Ukrainian firefighters

2018 ◽  
pp. 24-29
Author(s):  
A. N. Sukholentsev ◽  
A. I. Кraisvitniy ◽  
V. B. Kovalchuk ◽  
V. P. Cherniy ◽  
N. D. Kovalchuk
Keyword(s):  
Executive Functioning ◽  
Sleep Quality ◽  
Sleep Deprivation ◽  
Sleep Disorders ◽  
Sleep Disturbances ◽  
Depressive Disorders ◽  
Metabolic Diseases ◽  
Protective Measure ◽  
Statistical Tool ◽  
Rescue Service

Sleep deprivation is one of the main professionally determined factors for firefighters which can decrease their executive functioning and contribute to an array of health problems in them, including cardiovascular disease, diabetes, and depression mood disorders. The aim of this research is to gather preliminary data regarding the health of Ukrainian, with a focus on sleep quality indicators. Sleep-deprived participants in our research study were identified using such questionnaires as PSQI, ISI, ESS, SSS, FSS, and BQSA. Statistical processing of the data was carried out with the aid of Fisher's exact test, a statistical tool which is widely used in medical researches when the expected numbers are small. The obtained results confirm the presence of certain regularities. First, typical for the firefighting profession sleep disorders were detected among workers of operatively rescue service of Kropyvnitskiy city: including daytime fatigue, low sleep quality, insomnia, apnea, restless leg syndrome, low alertness, daytime sleepiness. Secondly, individuals suffering from sleep deprivation are at a higher risk for developing certain cardiovascular and metabolic diseases, depressive disorders, including increased impulsivity and overall lack of executive functioning. Thirdly, the importance of early detection and treatment for sleep disorders as a protective measure against the development of the aforementioned diseases has been stressed in our study. Sleep hygiene education should be provided to Ukrainian firefighters. It could influence them to make better choices related to their sleep, which would subsequently impact other areas of their health and wellbeing. Annual research studies concerning firefighters' sleep quality should be conducted in Ukraine on a regular basis with the aim to accumulate relevant statistics on the topic under consideration.

An overview of sleep dysfunction in Parkinson disease

2017 ◽  
Author(s):  
Elisaveta Sokolov ◽  
K. Ray Chaudhuri
Keyword(s):  
Quality Of Life ◽  
Parkinson Disease ◽  
Sleep Disturbance ◽  
Sleep Disorders ◽  
Sleep Disturbances ◽  
Sleep Problems ◽  
Case Series ◽  
Nocturnal Sleep ◽  
Drug Induced

Disturbances in nocturnal sleep and their consequences during waking in Parkinson disease (PD) were recognized in 1817 by James Parkinson, who described sleep problems in his case series as follows: “His attendants observed, that of late the trembling would sometimes begin in his sleep, and increase until it awakened him: when he always was in a state of agitation and alarm.” Sleep disturbance in PD is complex, with a prevalence of up to 98%, and has been shown to be a key determinant of quality of life. Sleep disturbances in PD are heterogeneous, ranging from insomnia to drug-induced sleep disorders, and now can be assessed by simple validated bedside tools such as the Parkinson’s Disease Sleep Scale (PDSS). Also, sleep, contrary to previous perceptions, can be disordered not just in advanced PD, but also in the pre-motor as well as the untreated states.

scholarly journals The Role of Sleep Disturbance, Depression and Anxiety in Frail Patients with AF–Gender Differences

2020 ◽  
Vol 10 (1) ◽  
pp. 11
Author(s):  
Beata Jankowska-Polańska ◽  
Jacek Polański ◽  
Krzysztof Dudek ◽  
Agnieszka Sławuta ◽  
Grzegorz Mazur ◽  
...  
Keyword(s):  
Gender Differences ◽  
Sleep Disturbance ◽  
Sleep Disturbances ◽  
Depressive Disorders ◽  
Reference Group ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Frail Patients ◽  
Anxiety Depression ◽  
The Impact

The aim of the study was to assess the link between anxiety and depression and frailty syndrome (FS) in patients with atrial fibrillation (AF) with regard to gender differences. Material and methods. The study was conducted on 158 patients with AF (mean age 70.4 ± 7.6). The study used the hospital anxiety and depression scale (HADS-M), the Athens insomnia scale (AIS) and the Edmonton frailty scale to assess and compare anxiety, depression, and sleep disturbance between frail and non-frail patients with AF. Results. FS was diagnosed in 53.2% of patients. A comparative analysis showed a statistically significantly higher severity level of anxiety (12.0 ± 2.6 vs. 8.4 ± 2.5, p < 0.001) and depression (12.5 ± 2.5 vs. 7.2 ± 3.3, p < 0.001) in frail patients compared to non-frail patients. The analysis of the level of anxiety, depression and FS did not show any significant differences between the studied women and men. However, statistically, significant differences were observed when FS occurred, regardless of gender. Anxiety disorders were observed in 75.5% of patients with FS and in 16.7% without frailty, whereas depressive disorders were observed in 73.6% of frail patients and in 4.2% without frailty. In an analysis of the impact of cumulative variables on the level of frailty, the risk of FS in patients with anxiety/depression and sleep disturbance is almost 500 times higher compared to patients without anxiety/depression and sleep disturbance. The risk of frailty in patients with sleep disturbance only is thirteen times higher than in the reference group, i.e., in patients without depression/anxiety and sleep disturbances. Conclusions: Patients with AF and FS show deeper anxiety, depression and sleep disturbances. Gender does not influence the risk of frailty in AF patients. Frailty in patients with AF is associated with a higher risk of depression, sleep disturbances and anxiety.

scholarly journals Experimental study of sleep disturbances in firefighters of the city of Kropyvnitskiy and the region

2019 ◽  
Vol 23 (3) ◽  
pp. 504-508
Author(s):  
A.N. Sukholentsev ◽  
N.D. Kovalchuk
Keyword(s):  
Executive Functioning ◽  
Sleep Quality ◽  
Sleep Deprivation ◽  
Sleep Disorders ◽  
Quantitative Research ◽  
Sleep Disturbances ◽  
Depressive Disorders ◽  
Research Study ◽  
Protective Measure ◽  
The City

Sleep deprivation is one of the primary work-related health issues facing professional firefighters which can decrease their executive functioning and contribute to an array of health problems in them. The aim of this exploratory, quantitative research study is to gather preliminary data regarding the health of Ukrainian rescuers, with a focus on sleep. Sleep-deprived participants in our research study were identified using such questionnaires as PSQI, ISI, ESS, SSS, FSS, and BQSA. The obtained results confirm the presence of certain regularities. Typical for the firefighting profession sleep disorders were detected among firefighters of the city of Kropyvnitskiy and the region, including insomnia, apnea, restless leg syndrome (RLS), daytime sleepiness and low alertness, daytime fatigue, low sleep quality. Individuals suffering from sleep deprivation are at a higher risk for developing certain cardiovascular and metabolic issues, depressive disorders. Also, we found out that the aforementioned sleep disturbances contributed to a higher level of impulsivity and overall lack of executive functioning in firefighters. In our study we outline the importance of early detection and treatment for sleep disorders as a protective measure against the development of professional diseases. Sleep hygiene education should be provided to Ukrainian firefighters. It could influence them to make better choices related to their sleep, which would subsequently impact other areas of their health and wellbeing. Annual research studies concerning firefighters' sleep quality should be conducted on a regular basis with the aim to accumulate relevant statistics on the topic under consideration.

scholarly journals New awakenings: current understanding of sleep dysfunction and its treatment in Parkinson’s disease

2019 ◽  
Vol 267 (1) ◽  
pp. 288-294 ◽  
Author(s):  
Lindsay H. M. Keir ◽  
David P. Breen
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Sleep Disorders ◽  
Sleep Disturbances ◽  
Disease Process ◽  
Underlying Disease ◽  
Prodromal Phase ◽  
Waste Products ◽  
New Treatment

AbstractThe non-motor features of Parkinson’s disease (PD) are increasingly being recognised. This review deals with the spectrum of sleep disorders associated with PD, which have a multifactorial aetiology and can significantly have an impact on the quality of life of patients and their carers. Some sleep disorders represent a prodromal phase of PD, with REM sleep behaviour disorder (RBD) being of particular interest in this regard, whereas others become more common as the disease advances. Understanding the pathophysiology of these sleep disturbances will hopefully lead to new treatment opportunities in the future. The recent discovery of the glymphatic system for removal of waste products from the brain has also raised the possibility that sleep disruption may cause or accelerate the underlying disease process.

scholarly journals Sleep Disturbance, Cognitive Decline, and Dementia: A Review

2017 ◽  
Vol 37 (04) ◽  
pp. 395-406 ◽  
Author(s):  
Mark Wu ◽  
Paul Rosenberg ◽  
Adam Spira ◽  
Alexandra Wennberg
Keyword(s):  
Cognitive Decline ◽  
Sleep Disturbance ◽  
Sleep Disorders ◽  
Sleep Disturbances ◽  
Sleep Problems ◽  
Behavior Disorder ◽  
Sleep Behavior ◽  
Disturbed Sleep ◽  
People With Dementia ◽  
Sleep Parameters

AbstractApproximately half of older people report sleep disturbances, which are associated with various health conditions, including neurodegenerative disease and dementia. Indeed, 60 to 70% of people with cognitive impairment or dementia have sleep disturbances, which are linked to poorer disease prognosis. Sleep disturbances in people with dementia have long been recognized and studied; however, in the past 10 years, researchers have begun to study disturbed sleep, including sleep fragmentation, abnormal sleep duration, and sleep disorders, as risk factors for dementia. In this review the authors summarize evidence linking sleep disturbance and dementia. They describe how specific aspects of sleep (e.g., quality, duration) and the prevalence of clinical sleep disorders (e.g., sleep-disordered breathing, rapid eye movement sleep behavior disorder) change with age; how sleep parameters and sleep disorders are associated with the risk of dementia; how sleep can be disturbed in dementia; and how disturbed sleep affects dementia prognosis. These findings highlight the potential importance of identifying and treating sleep problems and disorders in middle-aged and older adults as a strategy to prevent cognitive decline and dementia. The authors also review recent evidence linking sleep disturbances to the pathophysiology underlying dementing conditions, and briefly summarize available treatments for sleep disorders in people with dementia.

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