A Serious Public Health Concern for India due to Newly Discovered Virus (COVID-19): Early Detection of all Possible Cases is the Only Way to Combat

2020 ◽  
Author(s):  
Vijay Kumar Mishra
Keyword(s):  
Public Health ◽  
Surveillance System ◽  
Case Fatality Rate ◽  
Case Fatality ◽  
Public Health Problem ◽  
World Health ◽  
Health Concern ◽  
Family Welfare ◽  
Fatality Rate ◽  
Monitoring And Surveillance

Background: It is well known that India is having a massive population (around 130 crores) after China. So, it's more likely to be similar or more positive cases of corona among Indians. However, we are following the ways of social distancing and all possible ways to weaken the corona outbreak. But, India needs a good monitoring and surveillance system to tackle this problem otherwise it may become a serious public health problem. Objectives: This study has done to understand the severity of corona in India and its states and to device a tool based on symptoms suggested by the World Health Organization on the corona. Methods: We have utilized data extracted through the Ministry of Health & Family Welfare, GoI from 30th Jan to 26th March 2020. We have estimated the case fatality rate and cured rate to understand the severity of the newly discovered virus (COVID-19). Results: Out of 694 confirmed corona cases, 47 were foreigners and 647 Indians. Our study found that the case fatality rate due to COVID-19 was 23.1 per 1000 persons in India while the people who were still hospitalized under isolation wards were about 91 percent. The cure rate was estimated at around 64.8 per 1000 persons. Conclusions: Looking at the recovery rate, we may think about the severity of corona among Indians. We can reduce the chances of rapidly increasing corona cases through good monitoring and surveillance system. It is recommended that Government should not only focus on testing the passengers arriving at the airport but also test as much as possible cases based on the symptoms of corona in all the districts so that an actual number of cases can be estimated.

Impact of hydroxychloroquin/azithromycin protocol on COVID-19 case-fatality rate reduction in Algeria. (Preprint)

2020 ◽  
Author(s):  
Ahmed Youssef Kada
Keyword(s):  
Case Fatality Rate ◽  
Doubling Time ◽  
Case Fatality ◽  
World Health ◽  
Fatality Rate ◽  
Therapeutic Protocol ◽  
First Case ◽  
The World ◽  
The Impact ◽  
At Home

BACKGROUND Covid-19 is an emerging infectious disease like viral zoonosis caused by new coronavirus SARS CoV 2. On December 31, 2019, Wuhan Municipal Health Commission in Hubei province (China) reported cases of pneumonia, the origin of which is a new coronavirus. Rapidly extendable around the world, the World Health Organization (WHO) declares it pandemic on March 11, 2020. This pandemic reaches Algeria on February 25, 2020, date on which the Algerian minister of health, announced the first case of Covid-19, a foreign citizen. From March 1, a cluster is formed in Blida and becomes the epicentre of the coronavirus epidemic in Algeria, its total quarantine is established on March 24, 2020, it will be smoothly alleviated on April 24. A therapeutic protocol based on hydroxychloroquine and azithromycin was put in place on March 23, for complicated cases, it was extended to all the cases confirmed on April 06. OBJECTIVE This study aimed to demonstrate the effectiveness of hydroxychloroquin/azithromycin protocol in Algeria, in particular after its extension to all patients diagnosed COVID-19 positive on RT-PCR test. We were able to illustrate this fact graphically, but not to prove it statistically because the design of our study, indeed in the 7 days which followed generalization of therapeutic protocol, case fatality rate decrease and doubling time increase, thus confirming the impact of wide and early prescription of hydroxychloroquin/azithromycin protocol. METHODS We have analyzed the data collected from press releases and follow-ups published daily by the Ministry of Health, we have studied the possible correlations of these data with certain events or decisions having a possible impact on their development, such as confinement at home and its reduction, the prescription of hydroxychloroquine/azithromycin combination for serious patients and its extension to all positive COVID subjects. Results are presented in graphics, the data collection was closed on 31/05/2020. RESULTS Covid-19 pandemic spreads from February 25, 2020, when a foreign citizen is tested positive, on March 1 a cluster is formed in the city of Blida where sixteen members of the same family are infected during a wedding party. Wilaya of Blida becomes the epicentre of coronavirus epidemic in Algeria and lockdown measures taken, while the number of national cases diagnosed begins to increases In any event, the association of early containment measures combined with a generalized initial treatment for all positive cases, whatever their degree of severity, will have contributed to a reduction in the fatality rate of COVID 19 and a slowing down of its doubling time. CONCLUSIONS In Algeria, the rapid combination of rigorous containment measure at home and early generalized treatment with hydroxychloroquin have demonstrated their effectiveness in terms of morbidity and mortality, the classic measures of social distancing and hygiene will make it possible to perpetuate these results by reducing viral transmission, the only unknown, the reopening procedure which can only be started after being surrounded by precautions aimed at ensuring the understanding of the population. CLINICALTRIAL Algeria, Covid-19, pandemic, hydroxychloroquin, azithromycin, case fatality rate

scholarly journals Managing older adults’ fear of coronavirus disease: A new role for social work practice

2020 ◽  
pp. 147332502097329
Author(s):  
Hamed Mortazavi
Keyword(s):  
Older Adults ◽  
Case Fatality Rate ◽  
Severe Disease ◽  
Case Fatality ◽  
Social Work Practice ◽  
World Health ◽  
National Committee ◽  
Fatality Rate ◽  
Number Of Patients ◽  
Incidence And Mortality

As the number of patients infected with the 2019 novel coronavirus disease (nCOVID-19) increases, the number of deaths has also been increasing. According to World Health Organization (WHO), as of 4 October 2020, 34,804,348 cases had tested positive for nCOVID-19 globally, which among them, 1,030,738 confirmed deaths had occurred, equivalent to a case-fatality rate of 2.96%. However, in comparison with global statistics, the incidence and mortality of the nCOVID-19 infection are higher in Iran. As reported by the National Committee on COVID-19 Epidemiology of Ministry of Health of Iran, the total number of patients with confirmed COVID-19 infection has reached 468,119, of which 26,746 have died, equivalent to a case-fatality rate of 5.71%. Currently, there is solid evidence that older adults are at a higher risk of severe disease following infection from COVID-19.

scholarly journals KEPADATAN NYAMUK DEWASA Aedes Sp DI KELURAHAN MALALAYANG I KECAMATAN MALALAYANG MANADO PERIODE JANUARI – PEBRUARI 2010

2013 ◽  
Vol 3 (3) ◽  
Author(s):  
Janno B. B. Bernadus ◽  
Victor D. Pijoh ◽  
Venny Kareth
Keyword(s):  
Aedes Aegypti ◽  
Aedes Albopictus ◽  
Case Fatality Rate ◽  
Case Fatality ◽  
Public Health Problem ◽  
Hemorrhagic Fever ◽  
Adult Mosquito ◽  
Fatality Rate ◽  
North Sulawesi ◽  
Culex Sp

Abstract: Dengue Hemorrhagic Fever (DHF) has become a public health problem in Indonesia because of its high prevalence and ability to spread more widely. In North Sulawesi itself Case Fatality Rate of carrying dengue is increasing from year to year. The local village Malalayang has a high potential for spreading this disease. The result of an  entomology survey on adult mosquitos showed that Aedes sp was found in 40 houses of 80 house samples. From these 40 houses we got 71 mosquito samples. From these 71 samples tested and identified, we found three species: Aedes aegypti (30 samples, 42.25%), Aedes albopictus (22 samples, 30.99%), and Culex sp (19 samples, 26.76%). Mosquito density can be seen from the indices of the resting rates, which were 0.375 for Aedes aegypti, 0.275 for Aedes albopictus, and 0.65 for Aedes sp. Key words: density, adult mosquito, Aedes sp., resting rate.   Abstrak: Demam Berdarah Dengue (DBD) merupakan penyakit yang menjadi masalah kesehatan masyarakat di Indonesia karena prevalensinya yang tinggi dan penyebarannya semakin luas. Di Sulawesi Utara, Case Fatality Rate penyakit DBD tercatat terus meningkat dari tahun ke tahun. Kelurahan Malalayang I merupakan daerah yang potensial sebagai daerah penyebaran DBD. Survei entomologi terhadap nyamuk dewasa Aedes sp pada 80 rumah  memperlihatkan bahwa 40 diantaranya terdapat 71 sampel nyamuk. Setelah diperiksa dan diidentifikasi ternyata ditemukan tiga spesies yaitu Aedes aegypti 30 sampel (42,25%), Aedes albopictus 22 sampel (30,99%) dan Culex sp 19 (26,76%). Kepadatan nyamuk  dapat dilihat  dari angka indeks  pada resting rate yaitu Aedes aegypti = 0,375 , Aedes albopictus = 0,275 dan  Aedes sp.= 0,65. Kata kunci:  kepadatan, nyamuk dewasa, Aedes sp., resting rate.

scholarly journals Safety and Efficacy of Chloroquine/Hydroxychloroquine in SARS-CoV-2 Infection

2021 ◽  
Vol 33 (8) ◽  
pp. 1718-1722
Author(s):  
Alberto Boretti
Keyword(s):  
Case Fatality Rate ◽  
Case Fatality ◽  
Severe Pneumonia ◽  
World Health ◽  
Fatality Rate ◽  
Late Infection ◽  
Western Countries ◽  
Asymptomatic Patients ◽  
Overwhelming Evidence ◽  
Health Organization

This work summarizes the available evidence of the use of chloroquine/hydroxychloroquine (CQ/HCQ) in SARS-CoV-2 infection. Most of the published works indicate CQ/HCQ is likely effective against SARS-CoV-2 infection, almost 100% in prophylaxis and mild-medium severity cases and 60% in late infection cases. The percentage of positive works is larger if those works conducted under a probable conflict of interest are excluded from the list. Despite this overwhelming evidence from independent studies, the use of CQ/HCQ is currently limited or prevented in many western countries, based on a very singular examination of the science. The case of a work published in late May 2020, despite being openly defective and then retracted, prompted the World Health Organization (WHO) to ban the use of CQ/HCQ. This position has not yet rectified, thanks to the results of the not less questionable RECOVERY trial, where very sick patients were administered more than double the dose, over more than double the time, recommended for asymptomatic patients in current protocols of other countries, where CQ/HCQ are used for asymptomatic and mild but not severe pneumonia critically ill patients. While the case fatality rate does not depend only on therapies, it is finally shown based on the number of cases and fatalities per million and the case fatality rate as the western countries enforcing the ban on CQ/HCQ did not perform better, but much worse, than other countries, also because of therapies.

scholarly journals Covid-19 Fatality Rate in Third World Countries: A Review of Environmental Challenges and Impacts on Public Health and Human Security

2021 ◽  
Vol 9 (1) ◽  
pp. 39-44
Author(s):  
Chukwuemeka E. Etodike ◽  
◽  
Elsie C. Ekeghalu ◽  
Kelechi Johnmary Ani ◽  
Emmanuel Mutambara
Keyword(s):  
Public Health ◽  
Case Fatality Rate ◽  
Third World ◽  
Case Fatality ◽  
Personal Hygiene ◽  
Fatality Rate ◽  
Environmental Challenges ◽  
The Third ◽  
The Third World ◽  
Sanitary Conditions

The novel coronavirus is far from being over; with the case-fatality rate (CFR) hitting more than 16,500 globally as of July, there is a worry that despite the fact that the global CFR curve is showing signs of flattening, the environmental peculiarities of the third world countries may be abetting global efforts towards containing the virus. Therefore, this review x-rayed these peculiarities in the light of their current concern in public health as per their contribution to the persistent surge in CFR in most developing nations. Given that the virus is transmitted via droplets, the review focused on how the state of public and environmental challenges such as air as well as water pollution and personal hygiene could be abetting the surge in coronavirus infections and morbidity. The review revealed, among other things, that challenges associated with poor sanitary conditions, lack of potable water, unventilated environments, air pollution, and poor inter-personal hygiene are devastating challenges in the fight against the pandemic. The implication is that since these conditions are systematic in nature, it may take more than average effort and public sacrifice to checkmate the case-fatality rate of the virus in the third world. Therefore, call for studies is necessary to establish empiricism for CFR patterns and ratio across areas in deplorable environmental and sanitary conditions.

Subway-Related Trauma: An Urban Public Health Issue with a High Case-Fatality Rate

2018 ◽  
Vol 55 (2) ◽  
pp. 165-171.e1 ◽  
Author(s):  
Simon G. Rodier ◽  
Charles J. DiMaggio ◽  
Stephen Wall ◽  
Vasiliy Sim ◽  
Spiros G. Frangos ◽  
...  
Keyword(s):  
Public Health ◽  
Case Fatality Rate ◽  
Case Fatality ◽  
Health Issue ◽  
Public Health Issue ◽  
Fatality Rate ◽  
High Case Fatality Rate

Acute severe malnutrition treatment outcomes in children ages 6–59 months admitted to Singa Hospital, Sudan

2020 ◽  
Vol 114 (8) ◽  
pp. 612-617
Author(s):  
Jalal Ali Bilal ◽  
Hatim G Eltahir ◽  
Abdullah Al-Nafeesah ◽  
Osama Al-Wutayd ◽  
Ishag Adam
Keyword(s):  
Case Fatality Rate ◽  
Intestinal Parasites ◽  
Case Fatality ◽  
Clinical Information ◽  
Acute Malnutrition ◽  
World Health ◽  
Severe Malnutrition ◽  
Fatality Rate ◽  
Z Scores ◽  
Acute Severe Malnutrition

Abstract Background Acute malnutrition threatens the lives of 50.5 million children <5 y of age. Consequences of malnutrition include death, among other short-term sequelae. This study was conducted from April to October 2018 to determine the outcomes of children 6–59 months of age with acute severe malnutrition admitted to Singa Hospital in central Sudan. Methods Clinical information for children with a mid-upper arm circumference (MUAC) <115 mm were collected. We measured children's weight and height and calculated weight-for-height z-scores. Treatment was offered according to World Health Organization (WHO) guidelines. Outcomes were recorded as recovered, discharged against medical advice or died. Results This study included 376 malnourished children. The median age was 18 months (interquartile range [IQR] 12−24). The male:female ratio was 1:1. Among children with weight-for-height Z-scores of −4 and −3, 103 (27.3%) had oedematous malnutrition. There were 131 (34.8%) children with malaria parasites, 33 (8.7%) with pyuria and 24 (6.3%) with intestinal parasites. The recovery rate was 89.1%. The case fatality rate was 3.7%. Mortality was significantly increased with diarrhoea and dermatoses. There were no significant differences in the median of age (17.5 months [IQR 6−24] vs 18 [6−24], p = 0.595), MUAC (110 mm [IQR 104–111] vs 110 [100–111], p = 0.741) or sex (p = 0.991) between children who died and those who recovered. Conclusions The case fatality rate was 3.7% and it was associated with diarrhoea and dermatoses.

scholarly journals TUBERCULOSIS: EPIDEMIOLOGY AND CONTROL

2014 ◽  
Vol 6 (1) ◽  
pp. e2014070 ◽  
Author(s):  
Giorgia Sulis ◽  
Alberto Roggi ◽  
Alberto Matteelli ◽  
Mario C. Raviglione
Keyword(s):  
Public Health ◽  
Public Health Problem ◽  
Multidrug Resistant ◽  
World Health ◽  
Health Concern ◽  
Marginalized Groups ◽  
Tuberculosis Epidemiology ◽  
Slow Decline ◽  
Health Organization ◽  
And Control

Tuberculosis (TB) is a major public health concern worldwide: despite a regular, although slow, decline in incidence over the last decade, as many as 8.6 million new cases and 1.3 million deaths were estimated to have occurred in 2012. TB is by all means a poverty-related disease, mainly affecting the most vulnerable populations in the poorest countries. The presence of multidrug-resistant strains of M. tuberculosis in most countries, with some where prevalence is high, is among the major challenges for TB control, which may hinder recent achievements especially in some settings. Early TB case detection especially in resource-constrained settings and in marginalized groups remains a challenge, and about 3 million people are estimated to remain undiagnosed or not notified and untreated. The World Health Organization (WHO) has recently launched the new global TB strategy for the “post-2015 era” aimed at “ending the global TB epidemic” by 2035, based on the three pillars that emphasize patient-centred TB care and prevention, bold policies and supportive systems, and intensified research and innovation.This paper aims to provide an overview of the global TB epidemiology as well as of the main challenges that must be faced to eliminate the disease as a public health problem everywhere.

scholarly journals The burden of presumed tuberculosis in hospitalized children in a resource-limited setting in Papua New Guinea: a prospective observational study

2017 ◽  
Vol 9 (6) ◽  
pp. 374-378 ◽  
Author(s):  
Villa Watch ◽  
Jimmy Aipit ◽  
Tina Kote-Yarong ◽  
Allanie Rero ◽  
John W Bolnga ◽  
...  
Keyword(s):  
Papua New Guinea ◽  
Case Fatality Rate ◽  
Case Fatality ◽  
Public Health Problem ◽  
New Guinea ◽  
Final Diagnosis ◽  
Severe Malnutrition ◽  
Major Public Health Problem ◽  
Northern Coast ◽  
Fatality Rate

Abstract Background In Papua New Guinea, TB is considered to be a major public health problem, but little is known about the prevalence and prognosis of presumed TB in children. Methods As part of a prospective hospital-based surveillance on the northern coast of mainland Papua New Guinea, the authors investigated the admission prevalence and case fatality rate associated with presumed TB over a 6-year period (2011–2016). All children admitted who were diagnosed with TB were followed-up until discharge or death. Results Of 8992 paediatric admissions, 734 patients (8.2%) were diagnosed with presumed TB and there were 825 deaths, with TB accounting for 102 (12.4%). Extrapulmonary TB was the final diagnosis in 384 admissions {prevalence 4.3% [384/8992 (95% CI 3.9–4.7)]} with a case fatality rate of 21.4% [82/384 (95% CI 17.4–25.9)]. TB meningitis, disseminated TB and pericardial TB had high case fatality rates of 29.0% (53/183), 28.9% (11/38) and 25% (4/16), respectively. Severe malnutrition was more common in patients with pulmonary compared with extrapulmonary TB (25.4% vs 15.6%; p<0.01). Conclusions Improved community-based case detection strategies, routine BCG vaccinations and other effective forms of TB control need revitalization and sustainability to reduce the high case fatality rates associated with childhood TB in Papua New Guinea.

scholarly journals The influence of SARS-CoV-2 variants of concern on national case fatality rates

2021 ◽  
Author(s):  
William A. Barletta
Keyword(s):  
Case Fatality Rate ◽  
Temporal Dynamics ◽  
Case Fatality ◽  
Quantitative Measure ◽  
The United States ◽  
World Health ◽  
Fatality Rate ◽  
Wide Spread ◽  
The Face ◽  
Health Organization

AbstractBackgroundDuring 2021 several new variants of the SARS-CoV-2 virus appeared with both increased levels of transmissibility and virulence with respect to the original wild variant. The Delta (B.1.617.2) variation, first seen in India, dominates COVID-19 infections in several large countries including the United States and India. Most recently, the Lambda variant of interest with increased resistance to vaccines has spread through much of South America.ObjectiveThis research explores the degree to which new variants of concern 1) generate spikes and waves of fluctuations in the daily case fatality rates (CFR) across countries in several regions in the face of increasing levels of vaccination of national populations and 2) may increase the vulnerability of persons with certain comorbidities.MethodsThis study uses new, openly available, epidemiological statistics reported to the relevant national and international authorities for countries across the Americas, Europe, Africa, Asia and the Middle East. Daily CFRs and correlations of fatal COVID-19 infections with potential cofactors are computed for the first half of 2021 that has been dominated by the wide spread of several “variants of concern” as denoted by the World Health Organization.ResultsThe analysis yields a new quantitative measure of the temporal dynamics of mortality due to SARS-CoV-2 infections in the form of variations of a proxy case fatality rate compared on a country to-country basis in the same region. It also finds minimal variation of correlation between the cofactors based on WHO data and on the average apparent case fatality rate.

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