scholarly journals Post-COVID syndrome: A reflection and opinion paper

Author(s):  
Emilio Bouza ◽  
◽  
Rafael Cantón Moreno ◽  
Pilar De Lucas Ramos ◽  
Alejandra García-Botella ◽  
...  

A high proportion of people who have suffered from COVID-19 report, after recovery from the acute phase of the disease, clinical manifestations, both subjective and objective, that continue beyond 3 weeks or even 3 months after the original clinical disease. There is still no agreed nomenclature to refer to this condition, but perhaps the most commonly used is post-COVID syndrome. The Scientific Committee on COVID of the Madrid College of Physicians (ICOMEM) has discussed this problem with a multidisciplinary approach in which internists, infectious disease specialists, psychiatrists, pneumologists, surgeons, geriatricians, pediatricians, microbiologists, family physicians and other specialists have participated, trying to gather the existing information and discussing it in the group. The clinical manifestations are very variable and range from simple fatigue to persistent fibrosing lung lesions with objective alterations of pulmonary function. Post-COVID syndrome seems to be particularly frequent and severe in adults who have required admission to Intensive Care Units and has a peculiar behavior in a very small group of children. The post-COVID syndrome, which undoubtedly exists, is at first sight not clearly distinguishable from clinical manifestations that which occur after other acute viral diseases and after prolonged stays in ICUs due to other diseases. Therefore, it offers excellent research opportunities to clarify its pathogenesis and possibly that of other related entities. It is possible that progressively there will be an increased demand for care among the millions of people who have suffered and overcome acute COVID for which the health authorities should design mechanisms for the agile management of care that will possibly require well-coordinated multidisciplinary groups. This paper, structured in questions on different aspects of the post-COVID syndrome, attempts to stage the current state of this problem

Author(s):  
Ángela Milán-Tomás ◽  
Michelle Persyko ◽  
Martin del Campo ◽  
Colin M. Shapiro ◽  
Karl Farcnik

AbstractThe purpose of this review is to provide an update of the research regarding the etiology, diagnosis and management of psychogenic non-epileptic seizures (PNES). A literature search using Pubmed, Ovid MEDLINE and EMBASE database was performed from 2000 up to August 2017. We have evaluated the different factors leading to PNES as well as the diagnostic approach and management of this disorder which continue to be very difficult. The coexistence of epilepsy and PNES poses special challenges and requires the coordinated efforts of the family physicians, psychiatrists, psychologists and neurologists. Although this condition has an overall poor prognosis, a multidisciplinary approach in the diagnosis and management of this disorder would likely improve the outcomes. We have proposed a diagnostic and treatment algorithm for PNES and suggested a national registry of patients suffering from this condition. The registry would contain data regarding treatment and outcomes to aid in the understanding of this entity.


Author(s):  
Steven Taylor

This article reviews the current state of knowledge and promising new directions concerning the psychology of pandemics. Pandemics are disease outbreaks that spread globally. Historically, psychological factors have been neglected by researchers and health authorities despite evidence that pandemics are, to a large extent, psychological phenomena whereby beliefs and behaviors influence the spreading versus containment of infection. Psychological factors are important in determining ( a) adherence to pandemic mitigation methods (e.g., adherence to social distancing), ( b) pandemic-related social disruption (e.g., panic buying, racism, antilockdown protests), and ( c) pandemic-related distress and related problems (e.g., anxiety, depression, posttraumatic stress disorder, prolonged grief disorder). The psychology of pandemics has emerged as an important field of research and practice during the coronavirus 2019 (COVID-19) pandemic. As a scholarly discipline, the psychology of pandemics is fragmented and diverse, encompassing various psychological subspecialties and allied disciplines, but is vital for shaping clinical practice and public health guidelines for COVID-19 and future pandemics. Expected final online publication date for the Annual Review of Clinical Psychology, Volume 18 is May 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.


2020 ◽  
pp. 30-36
Author(s):  
I.N. Solovyova ◽  
◽  
Yu.V. Polyakova ◽  
G.E. Cherkasov ◽  
N.A. Trekova ◽  
...  

The research focus of the publication is the problem of preserving the blood of the operated patient. The variety of blood preservation methods shows the multidisciplinary nature of the problem and the importance of well-coordinated teamwork of busy doctors. For more than 20 years, surgical, anesthetic, transfusion technologies of blood saving have been used mainly in cardiac surgery patients. The use of a complex of blood-saving technologies allows you to reduce the amount of blood loss and the consumption of donor blood components. Over 7 years in cardiac surgery, the number of recipients of donor hemocomponents decreased by 41% (erythrovesue) and 61% (FFP). Autologous plasma is 68-78% of the total volume transfused to cardiac patients. 50% of patients operated on the ascending aorta do not need a blood transfusion. Blood loss during extensive liver resections has decreased three times in 10 years and does not require allogeneic blood transfusions. An adequate multidisciplinary approach to solving the problem of blood conservation can improve the results of surgical treatment of patients.


2019 ◽  
Vol 8 (1) ◽  
pp. 101 ◽  
Author(s):  
Sara Torretta ◽  
Claudio Guastella ◽  
Paola Marchisio ◽  
Tal Marom ◽  
Samantha Bosis ◽  
...  

Sinonasal-related orbital infections (SROIs) are typically pediatric diseases that occur in 3–4% of children with acute rhinosinusitis. They are characterised by various clinical manifestations, such as peri-orbital and orbital cellulitis or orbital and sub-periosteal abscesses that may develop anteriorly or posteriorly to the orbital septum. Posterior septal complications are particularly dangerous, as they may lead to visual loss and life-threatening events, such as an intracranial abscess and cavernous sinus thrombosis. Given the possible risk of permanent visual loss due to optic neuritis or orbital nerve ischemia, SROIs are considered ophthalmic emergencies that need to be promptly recognised and treated in an urgent-care setting. The key to obtaining better clinical outcomes in children with SROIs is a multi-disciplinary assessment by pediatricians, otolaryngologists, ophthalmologists, radiologists, and in selected cases, neurosurgeons, neurologists, and infectious disease specialists. The aim of this paper is to provide an overview of the pathogenesis, clinical manifestations, diagnosis, and treatment of pediatric SROIs, and to make some practical recommendations for attending clinicians.


Author(s):  
Mathieu Levesque ◽  
Charles Deacon ◽  
Suzie Adam ◽  
Christian Iorio-Morin

ABSTRACT: Cortical spreading depolarization (CSD) is recognized as a cause of transient neurological symptoms (TNS) in various clinical entities. Although scientific literature has been flourishing in the field of CSD, it remains an underrecognized pathophysiology in clinical practice. The literature evoking CSD in relation to subdural hematoma (SDH) is particularly scarce. Patients with SDH frequently suffer from TNS, most being attributed to seizures despite an atypical semiology, evolution, and therapeutic response. Recent literature has suggested that a significant proportion of those patients’ TNS represent the clinical manifestations of underlying CSD. Recently, the term Non-Epileptical Stereoytpical Intermittent Symptoms (NESIS) has been proposed to describe a subgroup of patients presenting with TNS in the context of SDH. Indirect evidence and recent research suggest that the pathophysiology of NESIS could represent the clinical manifestation of CSD. This review should provide a concise yet thorough review of the current state of literature behind the pathophysiology of CSD with a particular focus on recent research and knowledge regarding the presence of CSD in the context of subdural hematoma. Although many questions remain in the evolution of knowledge in this field would likely have significant diagnostic, therapeutic, and prognostic implications.


2006 ◽  
Vol 23 (7-8) ◽  
pp. 293-304 ◽  
Author(s):  
Tomoko Tamari

Although Japan had its own distinctive ‘pre-history’ of cultural studies, which produced some excellent research on popular culture, which can be traced back to the 1920s, the current state of cultural studies has been criticized by conventional mainstream academics; whereas the younger generation has been attracted by cultural studies as a new academic trend. An important new development in cultural studies in Japan is Cultural Typhoon. This new movement seeks to avoid institutionalization and create an alternative academic public sphere alongside broadened cultural practices, social activities and political interventions. Cultural studies in Japan can be seen as a part of a new diversity in cultural studies, which has some potentialities to move beyond the academy and open new dialogical spaces for communication and cultural intervention.


Cancers ◽  
2021 ◽  
Vol 13 (20) ◽  
pp. 5131
Author(s):  
David F. Moreno ◽  
Laura Rosiñol ◽  
María Teresa Cibeira ◽  
Joan Bladé ◽  
Carlos Fernández de Larrea

Monoclonal gammopathy of undetermined significance (MGUS) is defined as the presence of a monoclonal protein (M-protein) produced by a small amount of plasma cells. The majority of patients remain asymptomatic; however, a fraction of them develop clinical manifestations related to the monoclonal gammopathy despite not fulfilling criteria of multiple myeloma or other lymphoproliferative disorder. These patients constitute an emerging clinical issue coined as monoclonal gammopathy of clinical significance (MGCS). The mechanisms involved are poorly understood, and literature is scarce regarding management. The clinical spectrum involves symptoms related to renal, neurologic, skin, ocular, or bleeding manifestations, requiring a multidisciplinary approach. Treatment strategies rely on the basis of symptomatic disease and the M-protein isotype. In this review, we focus on MGCS other than renal, as the latter was earliest recognized and better known. We review the literature and discuss management from diagnosis to treatment based on illustrative cases from daily practice.


2016 ◽  
Vol 3 (2) ◽  
pp. 100
Author(s):  
Laras Budiyani ◽  
Adeputri Tanesha Idayu ◽  
Ika Prasetya Wijaya ◽  
Alvina Widhani

Sindrom hiper IgE (HIES) adalah suatu defisiensi kompleks imun primer yang jarang terjadi, memiliki manifestasi klinis yang beragam. Mutasi STAT 3 merupakan dasar dari sindrom hiper IgE klasik yang berhubungan dengan abnormalitas wajah, gigi, rangka, dan jaringan ikat yang tidak terlihat pada tipe resesif. Abses kulit berulang adalah gambaran utama pada HIES. Pemphigoid bullosa adalah kelainan autoimun yang memiliki karakteristik manifestasi bula pada kulit terkait membrane mukosa. Adanya gangguan autoimun yang terjadi secara bersamaan merupakan kelainan yang jarang. Striktur esofagus adalah salah satu manifestasi membran mukosa yang jarang terjadi pada kelainan kulit bulosa ini. Oleh sebab itu, manajemen pada kasus ini memerlukan pendekatan multidisiplin termasuk manajemen nutrisi dan infeksi.Kata kunci: pemphigoid bullosa, sindrom hiper IgE, striktur esofagus Hyper-IgE Syndrome with Bullous Pemphigoid and Esophageal StrictureHyper IgE syndrome (HIEs) is a rare primary immune complex deficiency that has diverse clinical manifestations. STAT 3mutation is the basis of hyper IgE classic syndrome which was associated with abnormalities of the face, teeth, skeletonand connective tissue that is not visible on recessive type. Recurrent skin abscesses are the main chracteristic of HIEs. Bullosa pemphigoid is an autoimmune disorder that is characterized by bullae manifestation on the skin associated with mucous membranes. An autoimmune disorder that occurs simultaneously is generally rare. Esophagus stricture is one of mucous membrane manifestations that is rarely occurred in this bullous skin disorder. Therefore, the management of these casesrequire a multidisciplinary approach including nutrition and infection management.Keywords: esophagus stricture, hyper IgE syndrome, pemphigoid bullosa


2020 ◽  
Vol 16 (24) ◽  
pp. 68-76
Author(s):  
N.V. Bakulina ◽  
◽  
A.S. Nekrasova ◽  
A.Ya. Gudkova ◽  
E.L. Latariya ◽  
...  

This review is devoted to the current state of the problem of diagnosis of systemic amyloidosis at the outpatient stage and in a multidisciplinary hospital. The article summarizes the existing information about the variants of the clinical course and provides current methods of verification of this disease. In systemic amyloidosis, the involvement of different systems and organs in the pathological process, the variety of clinical manifestations and nonspecific complaints of the patient in the early stages of this disease often lead to untimely establishment of the correct diagnosis and late initiation of treatment, worsening the prognosis and posing a significant threat to the life of the patient. Early diagnosis of systemic amyloidosis allows the patient to start treatment on time and increases the chances of success


2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Stephanie Sobrepera ◽  
Eric Monroe ◽  
Joseph J. Gemmete ◽  
Danial Hallam ◽  
Jason W. Pinchot ◽  
...  

AbstractHereditary hemorrhagic telangiectasia (HHT) is a disorder that affects 1 in 5000–10,000 people worldwide and can result in devastating complications such as cerebral abscess, stroke, massive hemorrhage, and even death. HHT is an autosomal dominant disorder that leads to the formation of abnormal communication between the arteries and veins with a resultant spectrum of vascular anomalies. The disorder affects many organ systems and thus requires a dedicated multidisciplinary approach. Interventional radiologists are vital members of this team providing expertise not only in disease management, but in complex embolotherapy, helping to maintain the health of these patients. This article reviews clinical manifestations, screening guidelines, diagnostic criteria, and endovascular management of HHT.


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