scholarly journals CHILDREN CEMETERY OF 11th—12th c. AT THE PODIL DISTRICT OF KYIV

2019 ◽  
Vol 30 (1) ◽  
pp. 268-279
Author(s):  
O. D. Kozak
Keyword(s):  
Differential Diagnosis ◽  
Mortality Rate ◽  
Middle Ages ◽  
Young Women ◽  
Social Stress ◽  
Metabolic Disorders ◽  
Congenital Syphilis ◽  
The Other ◽  
Burial Ground ◽  
Sensitive Group

In the cities of the Middle Ages children was the most sensitive group of people who responded to starvation, infection and social stress with high mortality rate and increased morbidity. 7 children’s burials (one belongs to twins of 6—9 month), located relatively compact on the outskirts of the lower city, were investigated in this project. Most children died at the age between 1 month and 3 years old. They have vestiges of metabolic disorders (scurvy, rickets and anemia) and infectious diseases (tuberculosis, nonspecific meningitis) on the bones. In one case, differential diagnosis was performed between congenital syphilis and rickets. Both diseases rarely happened in ancient Kiev. The pathological profile virtually repeats the pattern of morbidity in adolescents and young women buried in the marginal cemeteries of Podil. Regarding, studied complex can be considered a children’s quarter on the territory of some burial ground of the period. On the other hand, the similarity of the symptoms in most children, as well as two children (possibly twins) in one coffin indicates that at least part of them could die during one of the epidemics that took place in Kiev during the 11th—12th centuries which were obviously the most active on Podil.

scholarly journals Obesity and cahexia as the first manifestations of craniopharingioma

2018 ◽  
Vol 15 (1) ◽  
pp. 43-49 ◽  
Author(s):  
Liudmila I. Astafieva ◽  
Irina S. Klochkova ◽  
Pavel L. Kalinin ◽  
Boris A. Kadashev ◽  
Aleksandr N. Konovalov ◽  
...  
Keyword(s):  
Energy Balance ◽  
Young Women ◽  
Energy Exchange ◽  
Metabolic Disorders ◽  
Energy Homeostasis ◽  
The Other ◽  
Hypothalamic Region ◽  
Clinical Observations

The key structure in the regulation of energy homeostasis is the hypothalamus. The damage of the hypothalamic region can lead to imbalance of energy exchange with the development of obesity or cachexia. The most common metabolic disorders occur in case of craniopharyngiomas. The article presents two clinical observations of papillary craniopharyngioma in young women. Cases were accompanied by different disturbances of the energy balance, in one - with the development of obesity, in the other - cachexia.

The Relationship Between Suicidal Thinking and Dating Violence in a Sample of Adolescent Abortion Patients

Crisis ◽  
2011 ◽  
Vol 32 (5) ◽  
pp. 246-253 ◽  
Author(s):  
Gretchen E. Ely ◽  
William R. Nugent ◽  
Julie Cerel ◽  
Mholi Vimbba
Keyword(s):  
Unintended Pregnancy ◽  
Dating Violence ◽  
Young Women ◽  
Psychosocial Problems ◽  
The Other ◽  
Assessment Scale ◽  
Adolescent Dating Violence ◽  
Adolescent Relationships ◽  
Suicidal Thinking ◽  
The Relationship

Background: The relationship between suicidal thinking and adolescent dating violence has not been previously explored in a sample of adolescent abortion patients. Aims: This paper highlights a study where the relationship between dating violence and severity of suicidal thinking was examined in a sample of 120 young women ages 14–21 seeking to terminate an unintended pregnancy. Methods: The Multidimensional Adolescent Assessment Scale and the Conflict in Adolescent Relationships Scale was used to gather information about psychosocial problems and dating violence so that the relationship between the two problems could be examined, while controlling for the other psychosocial problems. Results: The results suggest that dating violence was related to severity of suicidal thinking, and that the magnitude of this relationship was moderated by the severity of problems with aggression. Conclusions: Specifically, as the severity of participant’s general problems with aggression increased, the magnitude of the relationship between dating violence and severity of suicidal thinking increased. Limitations of the study and implications for practice are discussed.

ISLAMIC COINS FROM EASTERN GIZA (EGYPT)

2020 ◽  
pp. 57-62
Author(s):  
E. Yu. Goncharov ◽  
◽  
S. E. Malykh ◽  
Keyword(s):  
Middle Ages ◽  
Human Activity ◽  
The Other ◽  
Dynamic Nature ◽  
14Th Century ◽  
Modern Times ◽  
Ancient Egyptian ◽  
Ancient Rock ◽  
Oriental Studies ◽  
The Middle Ages

The article focuses on the attribution of one gold and two copper coins discovered by the Russian Archaeological Mission of the Institute of Oriental Studies RAS in the ancient Egyptian necropolis of Giza. Coins come from mixed fillings of the burial shafts of the Ancient Egyptian rock-cut tombs of the second half of the 3rd millennium B.C. According to the archaeological context, the coins belong to the stages of the destruction of ancient burials that took place during the Middle Ages and Modern times. One of the coins is a Mamluk fals dating back to the first half of the 14th century A.D., the other two belong to the 1830s — the Ottoman period in Egypt, and are attributed as gold a buchuk hayriye and its copper imitation. Coins are rare for the ancient necropolis and are mainly limited to specimens of the 19th–20th centuries. In general, taking into account the numerous finds of other objects — fragments of ceramic, porcelain and glass utensils, metal ware, glass and copper decorations, we can talk about the dynamic nature of human activity in the ancient Egyptian cemetery in the 2nd millennium A.D. Egyptians and European travelers used the ancient rock-cut tombs as permanent habitats or temporary sites, leaving material traces of their stay.

Management of the Dutch Waddensea

1984 ◽  
Vol 16 (3-4) ◽  
pp. 485-495 ◽  
Author(s):  
D Vreugdenhil
Keyword(s):  
The Netherlands ◽  
Middle Ages ◽  
Human Activities ◽  
Nature Reserve ◽  
The Other ◽  
Hydrological Processes ◽  
Dutch Government ◽  
Shallow Sea ◽  
Management Objectives ◽  
Late Middle Ages

It was not until the late Middle Ages that the sea penetrated far into the interior of The Netherlands, thus flooding three quarters of a million hectares of land. Since then half a million hectares have been reclaimed from the sea. The Dutch Government chose to preserve the remaining quarter of a million hectares of shallow sea with mudflats of the Waddensea as a nature reserve. The management objectives are at one hand to preserve all characteristic habitats and species with a minimal interference by human activities in geomorphological and hydrological processes, and at the other hand to guarantee the safety against the sea of the inhabitants of the adjacent mainland and islands and to facilitate certain economic and recreational uses of the Waddensea without jeopardizing the natural qualities. These objectives are being elaborated in managementplans.

Growth Characteristics of Activated Sludges Acclimated to para-Nitrophenol in Batch and Continuous Modes

1994 ◽  
Vol 29 (7) ◽  
pp. 327-333
Author(s):  
Y. Matsui ◽  
F. Yamaguchi ◽  
Y. Suwa ◽  
Y. Urushigawa
Keyword(s):  
Growth Characteristics ◽  
The Other ◽  
Operational Mode ◽  
Continuous Mode ◽  
Relative Resistance ◽  
Batch Mode ◽  
The Given ◽  
Operational Modes ◽  
Very High ◽  
Sensitive Group

Activated sludges were acclimated to p-nitrophenol (PNP) in two operational modes, a batch and a continuous. The operational mode of the PNP acclimation of activated sludges strongly affected the physiological characteristics of predominant microorganisms responsible for PNP degradation. Predominant PNP degraders in the sludge in batch mode (Sludge B) had lower PNP affinity and were relatively insensitive to PNP concentration. Those of the sludge in continuous mode (Sludge C), on the other hand, had very high PNP affinity and were sensitive to PNP. MPN enumeration of PNP degraders in sludge B and C using media with different PNP concentrations (0.05, 0.2,0.5 and 2.0 mM) supported the above results. Medium with 0.2 mM of PNP did not recover PNP degraders in sludge C well, while it recovered PNP degraders in sludge B as well as the medium with 0.05 mM did. When switching from one operational mode to the other, the predominant population in sludge B shifted to the sensitive group, but that of sludge C did not shift at the given loading of PNP, showing relative resistance to inhibitive concentration.

Bastard Feudalism and the Framing of Thirteenth-Century England

2018 ◽  
Author(s):  
Peter Coss
Keyword(s):  
Middle Ages ◽  
Thirteenth Century ◽  
Twelfth Century ◽  
The State ◽  
The Other ◽  
Great Work ◽  
Early Middle Ages ◽  
The One ◽  
The Relationship

In the introduction to his great work of 2005, Framing the Early Middle Ages, Chris Wickham urged not only the necessity of carefully framing our studies at the outset but also the importance of closely defining the words and concepts that we employ, the avoidance ‘cultural sollipsism’ wherever possible and the need to pay particular attention to continuities and discontinuities. Chris has, of course, followed these precepts on a vast scale. My aim in this chapter is a modest one. I aim to review the framing of thirteenth-century England in terms of two only of Chris’s themes: the aristocracy and the state—and even then primarily in terms of the relationship between the two. By the thirteenth century I mean a long thirteenth century stretching from the period of the Angevin reforms of the later twelfth century on the one hand to the early to mid-fourteenth on the other; the reasons for taking this span will, I hope, become clearer during the course of the chapter, but few would doubt that it has a validity.

scholarly journals Use tumor suppressor genes as biomarkers for diagnosis of non-small cell lung cancer

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Chuantao Zhang ◽  
Man Jiang ◽  
Na Zhou ◽  
Helei Hou ◽  
Tianjun Li ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Mortality Rate ◽  
Tumor Suppressor ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Network Effects ◽  
Small Cell ◽  
The Other ◽  
Small Cell Lung ◽  
High Efficient

AbstractLung cancer is the leading cause of death worldwide. Especially, non-small cell lung cancer (NSCLC) has higher mortality rate than the other cancers. The high mortality rate is partially due to lack of efficient biomarkers for detection, diagnosis and prognosis. To find high efficient biomarkers for clinical diagnosis of NSCLC patients, we used gene differential expression and gene ontology (GO) to define a set of 26 tumor suppressor (TS) genes. The 26 TS genes were down-expressed in tumor samples in cohorts GSE18842, GSE40419, and GSE21933 and at stages 2 and 3 in GSE19804, and 15 TS genes were significantly down-expressed in tumor samples of stage 1. We used S-scores and N-scores defined in correlation networks to evaluate positive and negative influences of these 26 TS genes on expression of other functional genes in the four independent cohorts and found that SASH1, STARD13, CBFA2T3 and RECK were strong TS genes that have strong accordant/discordant effects and network effects globally impacting the other genes in expression and hence can be used as specific biomarkers for diagnosis of NSCLC cancer. Weak TS genes EXT1, PTCH1, KLK10 and APC that are associated with a few genes in function or work in a special pathway were not detected to be differentially expressed and had very small S-scores and N-scores in all collected datasets and can be used as sensitive biomarkers for diagnosis of early cancer. Our findings are well consistent with functions of these TS genes. GSEA analysis found that these 26 TS genes as a gene set had high enrichment scores at stages 1, 2, 3 and all stages.

scholarly journals Validity of different copeptin assays in the differential diagnosis of the polyuria-polydipsia syndrome

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Clara Odilia Sailer ◽  
Julie Refardt ◽  
Claudine Angela Blum ◽  
Ingeborg Schnyder ◽  
Jose Alberto Molina-Tijeras ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Diagnostic Accuracy ◽  
Healthy Volunteers ◽  
Primary Outcome ◽  
The Other ◽  
Poor Correlation ◽  
Elisa Assay ◽  
Moderate Correlation ◽  
High Diagnostic Accuracy ◽  
Osmotic Stimulation

AbstractThe aim of this study was to correlate three commercially available copeptin assays and their diagnostic accuracy in the differential diagnosis of the polyuria-polydipsia syndrome. Analyzed data include repeated copeptin measures of 8 healthy volunteers and 40 patients with polyuria-polydipsia syndrome undergoing osmotic stimulation and of 40 patients hospitalized with pneumonia. Copeptin was measured using the automated Brahms KRYPTOR, the manual Brahms LIA and the manual Cloud Clone ELISA assay. Primary outcome was the interrater correlation coefficient (ICC) and diagnostic accuracy in the polyuria-polydipsia syndrome of the three assays. In healthy volunteers, there was a moderate correlation for the KRYPTOR and LIA (ICC 0.74; 95% CI 0.07 to 0.91), and a poor correlation for the KRYPTOR and ELISA (ICC 0.07; 95% CI − 0.06 to 0.29), as for the LIA and ELISA (ICC 0.04; 95% CI − 0.04 to 0.17). The KRYPTOR had the highest diagnostic accuracy (98% (95% CI 83 to100)), comparable to the LIA (88% (95% CI 74 to 100)), while the ELISA had a poor diagnostic accuracy (55% (95% CI 34 to 68)) in the differential diagnosis of the polyuria-polydipsia syndrome. The KRYPTOR and LIA yield comparable copeptin concentrations and high diagnostic accuracy, while the ELISA correlates poorly with the other two assays and shows a poor diagnostic accuracy for polyuria-polydipsia patients. The current copeptin cut-off is valid for the KRYPTOR and LIA assay. Our results indicate that interpretation with other assays should be performed with caution and separate validation studies are required before their use in differentiating patients with polyuria-polydipsia syndrome.Trial registration: NCT02647736 January 6, 2016/NCT01940614 September 12, 2013/NCT00973154 September 9, 2009.

Workshop 1: Differential Diagnosis

1997 ◽  
Vol 9 (S1) ◽  
pp. 85-86
Author(s):  
Martin Rossor
Keyword(s):  
Differential Diagnosis ◽  
Cognitive Impairment ◽  
Memory Impairment ◽  
The Other ◽  
Neuropsychological Measures ◽  
Clinical Criteria ◽  
Dementia Syndrome ◽  
Number Of Patients ◽  
Diagnostic Modalities ◽  
Made In

We were asked to consider differential diagnosis. We decided that it really is different from the other diagnostic modalities and cannot be treated in the same way as, for example, global or neuropsychological measures. In the context of this meeting, we believed it would be appropriate to consider clinical criteria. Thus, clinical criteria for the dementia syndrome as well as for specific diseases were discussed. We recognized that in the future, an increasing number of patients will present with cognitive impairment who do not fulfill the clinical criteria for dementia. These patients may alternatively have an isolated memory impairment syndrome. Nevertheless, a diagnosis will still need to be made in these patients, at least in terms of the underlying molecular pathology, in order to implement potential treatments.

scholarly journals Neuralgias of the Trigeminal Nerve

2000 ◽  
Vol 5 (1) ◽  
pp. 107-113 ◽  
Author(s):  
Allan S Gordon
Keyword(s):  
Neuropathic Pain ◽  
Differential Diagnosis ◽  
Trigeminal Neuralgia ◽  
Clinical Features ◽  
Trigeminal Nerve ◽  
Postherpetic Neuralgia ◽  
Facial Pain ◽  
The Other ◽  
Atypical Facial Pain ◽  
Trigeminal Neuropathic Pain

Practitioners are often presented with patients who complain bitterly of facial pain. The trigeminal nerve is involved in four conditions that are sometimes mixed up. The four conditions - trigeminal neuralgia, trigeminal neuropathic pain, postherpetic neuralgia and atypical facial pain - are discussed under the headings of clinical features, differential diagnosis, cause and treatment. This article should help practitioners to differentiate one from the other and to manage their care.

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