Optimization Of Diagnostics Of Nodular Thyroid Diseases Based On TI-RADS And TBSRTC Systems

2021 ◽  
Vol 03 (01) ◽  
pp. 117-123
Author(s):  
M. H. Usmanova ◽  
◽  
S. I. I smoilov ◽  
Keyword(s):  
Thyroid Diseases ◽  
Thyroid Pathology

To evaluate the effectiveness of the integrated use of TI-RADS and TBSRTC systems and their significance in the formation of therapeutic tactics in patients with nodular thyroid pathology.

scholarly journals Thyroid Lesion as a Manifestation of Comorbidity in Patients with Diabetic Polyneyropathy

2021 ◽  
pp. 36-40
Author(s):  
Hennadii Chupryna ◽  
Viktoriia Dubynetska
Keyword(s):  
Thyroid Diseases ◽  
Mcgill Pain Questionnaire ◽  
Type I ◽  
Pain Rating ◽  
Important Place ◽  
Neuropathic Pain Syndrome ◽  
Thyroid Pathology ◽  
Gastrointestinal Pathology ◽  
Group A ◽  
Group B

The study of clinical and anamnestic and paraclinical characteristics, highlighting their dominant features in patients with DP and existing thyroid diseases occupies an important place in modern neuroendocrinology and requires more focused attention of clinicians. The objective: to determine the leading clinical and laboratory-instrumental parameters in patients with DP and thyroid pathology, to analyze the mutual influence of neuroendocrine pathology on the patient’s somatoneurological condition. Materials and methods. Was done a clinical examination of 64 patients with DP , in 27 (42 %) of them was diagnosed the comorbid thyroid pathology, in 37 (58 %) it was absent. All patients were divided into two groups: with DP in the background of type I, II DM and thyroid pathology (A) and with DP in the background of type I, II DM without thyroid pathology (B). During the examination of patients were used clinical-anamnestic, clinical-neurological, laboratory-instrumental, neurophysiological methods of examination. Pain characteristics were assessed using the McGill Pain Questionnaire (MPQ). Statistic calculation was done in MS Excel 2003 and using the package for statistical analysis STATISTICA 10. Results. In patients of both groups comorbidly were dominated diseases of the cardiovascular system, in group A, increasingly was revealed gastrointestinal pathology. Polyneuritic disorders of sensitivity and autonomic-trophic disorders are more common in persons of group B, they have a higher frequency of comorbid pathology and longer duration of DM. In group A lack of Achilles and knee reflexes was recorded more often than in comparison group. In 18 (65 %) of the examined persons of group A was detected a fatty liver dystrophy by ultrasound scanning of the abdominal organs, which exceeds the number in group B – 13 (35 %). There is an inverse average dependence between the level of TSH and BMI (correlation coefficient = –0,65). The general index of pain rating (Pain Rating Index – PRI) in group A is higher (30,62±2,64 scores). Conclusions. Among the thyroid diseases in the examined patients of group A hypothyroidism was most often detected, so 30 % of patients had a pronounced violation of lipid metabolism in the form of obesity, besides, in this group the number of people with type II DM was prevailed. The influence of thyroid pathology on the manifestations of DP is reflected in the intensification of neuropathic pain syndrome. There is also a significant effect on the metabolism of fats and carbohydrates, which aggravate and sometimes deepen the somatic condition of the patient.

scholarly journals Social and hygienic assessment of the spread of thyroid diseases

2021 ◽  
Vol 65 (1) ◽  
pp. 37-44
Author(s):  
Konstantin V. Kondrat’ev ◽  
Pavel F. Kiku ◽  
Svetlana N. Beniova ◽  
Marina V. Li ◽  
Ol’ga G. Tsygankova ◽  
...  
Keyword(s):  
Iodine Deficiency ◽  
Physical Inactivity ◽  
Endocrine System ◽  
Statistical Processing ◽  
Thyroid Diseases ◽  
Thyroid Pathology ◽  
The Social ◽  
Correlation Pleiades ◽  
Deficiency Diseases ◽  
Combined Impact

Introduction. Iodine deficiency diseases (IDD) are currently one of the most common pathologies of the endocrine system. The development of these diseases in the Primorsky region depends on the sufficient intake of iodine and various factors of exogenous and endogenous nature. The identification and establishment of the contribution of social and hygienic nature factors in the comprehensive impact to the occurrence and development of thyroid diseases, including IDD, is an important area of research. The aim of the study is to obtain information about the social and hygienic factors that influence the occurrence and development of thyroid pathology, including iodine deficiency diseases. Material and methods. Based on statistical data the dynamics in the population prevalence of diseases of the endocrine system in the Primorsky region was analyzed. To identify social and hygienic factors, a survey of 222 patients of the Center of Endocrinology Regional Clinical Hospital No. 2 (Vladivostok) was performed. Statistical processing of the results of the sociological survey was carried out using the Terentyev correlation pleiades method. Results. The development of thyroid pathology, including IDD, is influenced by unfavorable environmental conditions, physical inactivity and stressful situations in the workplace, unfavorable occupational factors including an exposure to noise, dust, radiation from a personal computer, lifestyle factors due to low physical activity, non-compliance with the waking and sleeping regime. More often, thyroid diseases develop in women and people over 50 years of age. The development of IDD is influenced by the observance of the principles of rational nutrition and the presence of certain foods in the diet. The contribution of these factors in the conditions of their combined impact on the human body is established. Conclusion. The identified complex of social and hygienic factors that are important for the occurrence and development of thyroid diseases can be further used to create targeted programs for the prevention of these diseases in the population of the Primorsky region.

scholarly journals Skin lesions in thyroid diseases and syndromes associated with thyroid pathology

2020 ◽  
Vol 22 (7) ◽  
pp. 60-63
Author(s):  
Ekaterina A. Troshina ◽  
Keyword(s):  
Skin Lesions ◽  
Thyroid Diseases ◽  
Thyroid Pathology

Статья посвящена описанию различных дерматологических проявлений, характерных как для собственно заболеваний щитовидной железы, так и для синдромов, в состав которых они могут входить. Представлены собственные наблюдения. Сделан акцент на возможных механизмах, лежащих в основе поражений кожи при указанных заболеваниях. Ключевые слова: щитовидная железа, тиреотоксикоз, гипотиреоз, витилиго, алопеция, кандидоз, невринома, нейрофиброматоз, аутоиммунный полигландулярный синдром. Для цитирования: Трошина Е.А. Поражения кожи при заболеваниях щитовидной железы и синдромах, включающих тиреоидную патологию. Consilium Medicum. 2020; 22 (7): 60–63. DOI: 10.26442/20751753.2020.7.200289

scholarly journals Integrated ultrasound investigation and magnetic resonance tomography in the diagnosis of focal thyroid pathology

2012 ◽  
Vol 93 (3) ◽  
pp. 484-487 ◽  
Author(s):  
L A Timofeeva
Keyword(s):  
Magnetic Resonance ◽  
Thyroid Gland ◽  
Diagnostic Accuracy ◽  
Ultrasound Examination ◽  
Magnetic Resonance Tomography ◽  
Primary Diagnosis ◽  
Thyroid Diseases ◽  
Focal Lesions ◽  
Thyroid Pathology ◽  
Ultrasound Investigation

Aim. To determine the features an integrated ultrasound investigation and magnetic resonance tomography in the diagnosis of focal thyroid pathology. Methods. Integrated ultrasound examination was conducted in 1440 patients with focal lesions of the thyroid gland at the age of 17-76 years, and magnetic resonance tomography was performed in 91 patients (65 females and 26 males). Results. It was established that the informativeness of the ultrasound investigation is characterized by the following parameters: sensitivity - 92.1%, specificity - 78.6%, and diagnostic accuracy - 90.3%; the informativeness of magnetic resonance tomography: sensitivity - 94.1%, specificity - 89.6 %, and diagnostic accuracy - 91.0%. Conclusion. Integrated use of ultrasound investigation and magnetic resonance tomography significantly increases the informativeness during primary diagnosis of focal thyroid diseases.

scholarly journals Thyroid diseases and risk of non-thyroidal pathology

2017 ◽  
Vol 98 (1) ◽  
pp. 77-84 ◽  
Author(s):  
R I Glushakov ◽  
E V Kozyrko ◽  
I V Sobolev ◽  
S A Ermolova ◽  
O V Vlaseva ◽  
...  
Keyword(s):  
Integrin Αvβ3 ◽  
Epidemiological Data ◽  
Epidemiological Studies ◽  
Population Based ◽  
Thyroid Diseases ◽  
Tissue Response ◽  
Mitogen Activated Protein Kinase ◽  
Malignant Neoplasms ◽  
Thyroid Pathology ◽  
Mitogen Activated Protein

The review presents generalized epidemiological data on the prevalence of non-neoplastic thyroid pathology in developed and developing countries, in particular in regions with iodine deficiency and the influence of mass iodine prophylaxis on reducing the incidence and prevalence of thyroid diseases in these regions. The data on the prevalence of subclinical hypo- and hyperthyroidism are presented, where according to the averaged data 1 clinical manifestation of thyroid insufficiency accounted for 20 cases of unregistered subclinical hypothyroidism, and 1 case of identified thyroid hyperfunction accounted for 15 cases of subclinical hyperthyroidism. Methodological, clinical and social difficulties in studying the prevalence of thyroid pathology are described. The main nongenomic actions of thyroid hormones, which originated from extracellular domains of cell adhesion protein - integrin αVβ3, resulting in activation of mitogen-activated protein kinase, phosphatidylinositol-3 kinase and serine-threonine-protein kinases, are presented. The ultimate cell and tissue response to this stimulation is the activation of cell proliferation, angiogenesis, cell migration, and increased expression of tissue-specific proinflammatory genes, which ultimately lead to acceleration of the «cancer development and its natural history». Data from epidemiological studies, which established a correlation between thyroid status and incidence (prevalence) of malignant neoplasms, are given. As a result of population-based studies analysis it was demonstrated that long term hyperthyroidism increases the risk of developing malignant neoplasms of different localizations, in particular breast, ovarian, prostate and lung cancer.

Features of menstrual function in women with infertility and thyroid gland pathology

2017 ◽  
pp. 40-44
Author(s):  
T.G. Romanenko ◽  
◽  
O. Chayka ◽  
Keyword(s):  
Menstrual Cycle ◽  
Thyroid Gland ◽  
Detection Rate ◽  
Comparison Group ◽  
Thyroid Diseases ◽  
Menstrual Function ◽  
Thyroid Pathology ◽  
Group I ◽  
Clinical Variants ◽  
Cycle Disorders

The objective: the identification of features of menstrual cycle disorders (DMC) in women with infertility on the background of thyroid diseases (thyroid gland). Patients and methods. According to the purpose of the scientific research, 50 women with infertility and NMCs were examined on the background of thyroid diseases, which were included in the main group (group I). In patients of the comparison group (group II; n= 30), DMC was observed without thyroid pathology. Patients of group I, depending on the type of HMC and thyroid functional status, were distributed as follows: 8 patients had hypomenstrual syndrome with hypothyroidism, 7 patients with hyperthyroidism and 17 patients with euthyroid goiter. In 4 patients, the DMC was diagnosed as a hyperpolymenorea with hypothyroidism, in 12 patients with hyperthyroidism and in 2 patients with euthyroidism. Results. Application of the developed algorithm of examination of women with infertility allowed to increase the detection rate of their combined pathology in the form of thyroid disorders and menstrual function disorders. Conclusion. Reliable in comparison with women with infertility with violations of the menstrual cycle, but without the pathology of the thyroid gland, changes and peculiarities of the secretion of the spectrum of the studied hormones that correspond to the clinical variants of the combined pathology were recorded in the group of women with infertility on the background of thyroid gland diseases and accompanying violations of the menstrual function. Key words: menstrual cycle disorders, thyroid pathology, infertility.

scholarly journals Dynamics of epidemiological indicators of thyroid pathology in the population of the Russian Federation: analytical report for the period 2009–2018

2021 ◽  
Vol 67 (2) ◽  
pp. 10-19
Author(s):  
E. A. Troshina ◽  
N. M. Platonova ◽  
E. A. Panfilova
Keyword(s):  
Iodine Deficiency ◽  
Russian Federation ◽  
Deficiency Syndrome ◽  
Thyroid Diseases ◽  
Entire Population ◽  
Linear Regression Models ◽  
Thyroid Pathology ◽  
Autoimmune Pathology ◽  
The Russian Federation ◽  
Observation Period

BACKGROUND: The level of iodine consumption by the population largery determines the spectrum of thyroid pathology. To date, in the Russian Federation, iodine-deficiency disorders (IDD) occupy a leading position in the structure of all thyroid diseases. Chronic ID leads to adverse health consequences and significant economic costs for their elimination on a national scale. However, the spectrum of thyroid pathology is not limited to the problem of ID, and the study of other thyroid diseases is also of interest.AIMS: to assess the dynamics of prevalence and incidence of IDD and other thyroid diseases in the entire population of the RF for the period 2009–2018, using official state statistics.MATERIALS AND METHODS: the main epidemiological indicators (incidence and prevalence) of thyroid diseases in the entire population of the RF were analyzed using official state statistics. The analyzed period is 2009–2018. There was no medical intervention. To assess the dynamics of prevalence and incidence, a linear regression models were constructed, the slope of the trend line was calculated.RESULTS: the data were analyzed in accordance with the structure of diseases presented in the statistical reporting: goiter, thyroiditis, hypothyroidism, thyrotoxicosis, congenital iodine deficiency syndrome. For the ten-year period 2009–2018 there is a statistically significant increase in the prevalence of various forms of goiter, thyrotoxicosis, congenital iodine deficiency syndrome in the entire population of the Russian Federation. During the observation period, an increase in the incidence of thyrotoxicosis was revealed. With regard to the incidence of congenital iodine deficiency syndrome, only an upward trend was revealed. Despite the fact that during the observation period the number of new cases of various forms of goiter decreased, the prevalence of goiter among the population of the Russian Federation remains high: 1.2% of the population by January 1, 2019. with the growth of autoimmune pathology, improvement of the level of diagnosis, and also, in some cases, with overdiagnosis (for example, when diagnosing autoimmune thyroiditis in individuals with asymptomatic carriage of antithyroid antibodies). The current approaches to iodine prophylaxis are not effective enough.CONCLUSIONS: the results of the analysis indicate mainly an increase in the high prevalence of thyroid pathology among the population of the RF against the background of regional events. The problem of ID remains unresolved, which dictates the need to introduce universal mandatory salt iodization in the territory of the RF.

THE PREVALENCE OF THYROID LESION IN RHEUMATOID ARTHRITIS AMONG THE SOUTHERN RESIDENTS OF KYRGYZSTAN

2020 ◽  
Vol 20 (1) ◽  
pp. 226-233
Author(s):  
Zhazgul Abzhamilova ◽  
◽  
Abdimutalib Mamasaidov ◽  
Dilaram Abdurashitova ◽  
◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Autoimmune Thyroiditis ◽  
Social Problem ◽  
Death Rate ◽  
Thyroid Diseases ◽  
Thyroid Lesion ◽  
Thyroid Pathology ◽  
Rheumatoid Arthritis Activity

Rheumatoid arthritis (RA) is one of the most relevant but less studied medical and social problem of Kyrgyzstan. According to latest research of WHO, published in 2017, Kyrgyzstan is ranked second among world countries by rheumatoid arthritis-caused death rate. It is estimated, that autoimmune thyroiditis, hypothyroidism and thyrotoxicosis are associated comorbidities of rheumatoid arthritis. In Kyrgyzstan the autoimmune thyroiditis is ranked as second (8.9%) among the all thyroid diseases rate and considered to be the most frequent cause of hypothyroidism (7.2%). Meanwhile the thyrotoxicosis has been found in 6% of population, being on the fourth rank. The article shows the prevalence of thyroid pathology and its common nosological forms in patients with RA living in south of Kyrgyzstan, evaluates its association to rheumatoid arthritis’ activity. In RA patients the prevalence of autoimmune thyroiditis was found 12,6%, hypothyroidism (14,2)% (subclinical 13,0%, manifested in 1,2%), thyrotoxicosis in 1,2% cases.

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