scholarly journals A META-ANALYSIS ON THE EFFECTIVENESS OF MALARIA COMMUNITY-BASED INTERVENTION

2021 ◽  
Vol 3 (2) ◽  
pp. 467-478
Keyword(s):  
Search Strategy ◽  
Random Sequence ◽  
Meta Analysis ◽  
Integrated Approach ◽  
Medical Subject Headings ◽  
Community Based ◽  
Mesh Terms ◽  
Percentage Difference ◽  
Cochrane Database ◽  
Database Platform

Introduction: The community-based intervention was proven as one of the best approaches in combatting malaria. It is widely used to reduce malaria cases worldwide. A multisectoral approach must be made to ensure the success of the intervention. Therefore, this study is aimed is to determine the effectiveness of community-based intervention for malaria based on recent findings. Methods: A search strategy using Pub Med and Cochrane database platform investigating the effectiveness of malaria community-based intervention. There are selected terms and words predefined to obtain a comprehensive search strategy that included text fields within records and Medical Subject Headings (MeSH terms). Results: Eight articles were selected for this study. This review identified six communitybased interventions for malaria and four outcome measures. Most of the studies included a low risk of bias in each criterion except for random sequence and allocation of concealment. The meta-analysis found that the overall incidence difference of the included studies was significant (0.05 CI 0.02, 0.08), while the subgroup analysis of Permethrin LLIN the I2 was reduced to 75%. However, the overall usage percentage difference in health education and community mobilization to improve intervention usage was not significant (0.28 CI -0.02, 0.58). Conclusion: The community-based intervention approach is practical to fight malaria thus, to reduced mortality due to malaria. An integrated approach and engagement with multiagency will ensure outstanding achievement in fighting malaria.

scholarly journals Development of an efficient search filter to retrieve systematic reviews from PubMed

2021 ◽  
Vol 109 (4) ◽  
Author(s):  
José Antonio Salvador-Oliván ◽  
Gonzalo Marco-Cuenca ◽  
Rosario Arquero-Avilés
Keyword(s):  
Systematic Review ◽  
Decision Making ◽  
Systematic Reviews ◽  
Search Strategy ◽  
Average Precision ◽  
Search Filter ◽  
Search Terms ◽  
Mesh Terms ◽  
Cochrane Database ◽  
Relevant Publication

Objective: Locating systematic reviews is essential for clinicians and researchers when creating or updating reviews and for decision-making in health care. This study aimed to develop a search filter for retrieving systematic reviews that improves upon the performance of the PubMed systematic review search filter.Methods: Search terms were identified from abstracts of reviews published in Cochrane Database of Systematic Reviews and the titles of articles indexed as systematic reviews in PubMed. Both the precision of the candidate terms and the number of systematic reviews retrieved from PubMed were evaluated after excluding the subset of articles retrieved by the PubMed systematic review filter. Terms that achieved a precision greater than 70% and relevant publication types indexed with MeSH terms were included in the filter search strategy.Results: The search strategy used in our filter added specific terms not included in PubMed’s systematic review filter and achieved a 61.3% increase in the number of retrieved articles that are potential systematic reviews. Moreover, it achieved an average precision that is likely greater than 80%.Conclusions: The developed search filter will enable users to identify more systematic reviews from PubMed than the PubMed systematic review filter with high precision.

scholarly journals What Is the Clinical Evidence Supporting Trauma Team Training (TTT): A Systematic Review and Meta-Analysis

Medicina ◽  
2019 ◽  
Vol 55 (9) ◽  
pp. 551
Author(s):  
Noonan ◽  
Olaussen ◽  
Mathew ◽  
Mitra ◽  
Smit ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Outcomes ◽  
Patient Outcomes ◽  
Meta Analysis ◽  
Ct Scanning ◽  
Trauma Team ◽  
Team Training ◽  
Cochrane Library ◽  
Medical Subject Headings ◽  
Mesh Terms

Background and Objectives: Major trauma centres manage severely injured patients using multi-disciplinary teams but the evidence-base that targeted Trauma Team Training (TTT) improves patients’ outcomes is unclear. This systematic review aimed to identify the association between the implementation of TTT programs and patient outcomes. Methods: We searched OVID Medline, PubMed and The Cochrane Library (CENTRAL) from the date of the database commencement until 10 of April 2019 for a combination of Medical Subject Headings (MeSH) terms and keywords relating to TTT and clinical outcomes. Reference lists of appraised studies were also screened for relevant articles. We extracted data on the study setting, type and details about the learners, as well as clinical outcomes of mortality and/or time to critical interventions. A meta-analysis of the association between TTT and mortality was conducted using a random effects model. Results: The search yielded 1136 unique records and abstracts, of which 18 full texts were reviewed. Nine studies met final inclusion, of which seven were included in a meta-analysis of the primary outcome. There were no randomised controlled trials. TTT was not associated with mortality (Pooled overall odds ratio (OR) 0.83; 95% Confidence Interval; 0.64–1.09). TTT was associated with improvements in time to operating theatre and time to first computerized tomography (CT) scanning. Conclusions: Despite few publications related to TTT, its introduction was associated with improvements in time to critical interventions. Whether such improvements can translate to improvements in patient outcomes remains unknown. Further research focusing on the translation of standardised trauma team reception “actions” into TTT is required to assess the association between TTT and patient outcome.

scholarly journals Using MeSH (Medical Subject Headings) to Enhance PubMed Search Strategies for Evidence-Based Practice in Physical Therapy

2012 ◽  
Vol 92 (1) ◽  
pp. 124-132 ◽  
Author(s):  
Randy R. Richter ◽  
Tricia M. Austin
Keyword(s):  
Search Strategy ◽  
Evidence Based Practice ◽  
Physical Therapists ◽  
Mesh Term ◽  
Evidence Based ◽  
Medical Subject Headings ◽  
Search Terms ◽  
Mesh Terms ◽  
Subject Headings ◽  
Pubmed Search

Background Evidence-based practice (EBP) is an important paradigm in health care. Physical therapists report lack of knowledge and time constraints as barriers to EBP. Objective The purpose of this technical report is to illustrate how Medical Subject Headings (MeSH), a controlled vocabulary thesaurus of indexing terms, is used to efficiently search MEDLINE, the largest component of PubMed. Using clinical questions, this report illustrates how search terms common to physical therapist practice do or do not map to appropriate MeSH terms. A PubMed search strategy that takes advantage of text words and MeSH terms is provided. Results A search of 139 terms and 13 acronyms was conducted to determine whether they appropriately mapped to a MeSH term. The search results were categorized into 1 of 5 outcomes. Nearly half (66/139) of the search terms mapped to an appropriate MeSH term (outcome 1). When a search term did not appropriately map to a MeSH term, it was entered into the MeSH database to search for an appropriate MeSH term. Twenty-one appropriate MeSH terms were found (outcomes 2 and 4), and there were 52 search terms for which an appropriate MeSH term was not found (outcomes 3 and 5). Nearly half of the acronyms did not map to an appropriate MeSH term, and an appropriate MeSH term was not found in the database. Limitations The results are based on a limited number of search terms and acronyms. Conclusions Understanding how search terms map to MeSH terms and using the PubMed search strategy can enable physical therapists to take full advantage of available MeSH terms and should result in more-efficient and better-informed searches.

scholarly journals Burden and Determinant of Inadequate Dietary Diversity among Pregnant Women in Ethiopia: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Hagos Degefa Hidru ◽  
Meresa Berwo Mengesha ◽  
Yared Hailesilassie ◽  
Fissaha Tekulu Welay
Keyword(s):  
Dietary Intake ◽  
Pregnant Women ◽  
English Language ◽  
Dietary Diversity ◽  
Meta Analysis ◽  
National Level ◽  
Perinatal Outcomes ◽  
Cochrane Library ◽  
Medical Subject Headings ◽  
Mesh Terms

Background. Inadequate dietary diversity intake during pregnancy results in increased risks of negative maternal and perinatal outcomes. About one million neonates die on the first day of life due to inadequate dietary intake during pregnancy as a result of maternal complication and adverse birth outcomes. This review summarizes the burden of inadequate dietary diversity and its determinants among pregnant women at the national level of Ethiopia. Methods. Studies were retrieved from selected electronic databases, including PubMed, Cochrane Library, and Google Scholar. Random-effects model meta-analysis was used to estimate the pooled burden of inadequate dietary diversity and its determinants at a 95% confidence interval with its respective odds ratio (OR) using statistical R-software version 3.6.1. Moreover, quality appraisal of the included studies, publication bias, and level of heterogeneity were checked with subgroup analysis and sensitivity influential test. The searches were restricted to articles published in the English language only, and Medical Subject Headings (MeSH terms) was used to help expand the search in advanced PubMed search. Result. A total of 850 articles were identified through the initial search of which 21 studies were included in the final review yielding a total sample size of 9,230 pregnant women. The pooled prevalence of inadequate dietary diversity was 53% (95% CI: 44%, 62%). Food insecurity [AOR = 2.18, (95% CI: 1.02, 4.63)], family size of greater than four [AOR = 1.46, (95% CI: 1.10, 1.95)], rural residence [AOR = 4.52, (95% CI: 1.02, 20.09)], no formal educational status [AOR = 4.50, (95% CI: 1.02, 20.09)], and a lack of counseling about dietary diversity [AOR = 2.75, (95% CI: 2.17, 3.48)] were among the significantly associated factors for inadequate dietary diversity. Conclusion. In this review, there was a high prevalence of inadequate dietary diversity among pregnant women at the national level in Ethiopia. Therefore, strengthening early counseling and diagnosis of dietary intake and undernutrition during the antenatal care period is important.

scholarly journals Association of Apolipoprotein E Polymorphism With Risk of Metabolic Syndrome: A Case-Control Study And Meta‐Analysis

2021 ◽  
Author(s):  
Mahdi Safarpour ◽  
Bahareh Sedaghati-khayat ◽  
Leila Najd Hassan Bonab ◽  
Mohammad-Sadegh Fallah ◽  
Ahmad Ebrahimi ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Apolipoprotein E ◽  
Meta Analysis ◽  
Medical Subject Headings ◽  
The Metabolic Syndrome ◽  
Mesh Terms ◽  
Apolipoprotein E Polymorphism ◽  
Ε4 Allele ◽  
Genetic Pools ◽  
Control Study

Abstract Background: This study aimed to assess the genetic association between Apolipoprotein E (APOE) polymorphisms and susceptibility to metabolic syndrome (MetS) among the Tehran cardiometabolic genetic study (TCGS) participants. The results were then compared with similar studies in other populations using meta-analysis. Methods: the metabolic syndrome was defined according to the Joint Interim Statement (JIS) criteria. A total of 12282 subjects (5696 cases with metabolic syndrome and 6586 healthy controls) were genotyped using Human OmniExpress-24-v1-0 BeadChip. Subsequently, PubMed, Scopus, and Google Scholar databases were searched using relevant Medical Subject Headings (MeSH) terms to collect all studies that examined the association between polymorphisms of the APOE gene and risk of MetS. Results: the presence of the APOE-ε4 allele could not significantly increase the risk of MetS in the carriers of this allele compared to individuals lacking the risk allele in the TCGS population (OR = 1.11, 95% CI: 0.92 to 1.32). The meta-analysis results also indicated no significant association between the APOE-ε 4 allele and the risk of MetS. Conclusion: the frequency of the ε4 allele was almost same in the cases and the controls. Therefore, this allele cannot be considered as biomarker to predict the MetS susceptibility in the TCGS population or other populations with different genetic pools.

scholarly journals Mind the gap: identifying what is missed when searching only the broad scope with clinical queries

2019 ◽  
Vol 107 (3) ◽  
Author(s):  
Edwin Vincent Sperr Jr.
Keyword(s):  
Clinical Study ◽  
Search Strategy ◽  
Clinical Prediction ◽  
Medical Subject Headings ◽  
Individual Test ◽  
Diagnosis And Prognosis ◽  
Broad Scope ◽  
Mesh Terms ◽  
Substantial Risk ◽  
Clinical Queries

Objective: The PubMed Clinical Study Category filters are subdivided into “Broad” and “Narrow” versions that are designed to maximize either sensitivity or specificity by using two different sets of keywords and Medical Subject Headings (MeSH). A searcher might assume that all items retrieved by Narrow would also be found by Broad, but there are occasions when some [Filter name]/Narrow citations are missed when using [Filter name]/Broad alone. This study quantifies the size of this effect.Methods: For each of the five Clinical Study Categories, PubMed was searched for citations matching the query Filter/Narrow NOT Filter/Broad. This number was compared with that for Filter/Broad to compute the number of Narrow citations missed per 1,000 Broad. This process was repeated for the MeSH terms for “Medicine” and “Diseases,” as well as for a set of individual test searches.Results: The Clinical Study Category filters for Etiology, Clinical Prediction Guides, Diagnosis, and Prognosis all showed notable numbers of Filter/Narrow citations that were missed when searching Filter/Broad alone. This was particularly true for Prognosis, where a searcher could easily miss one Prognosis/Narrow citation for every ten Prognosis/Broad citations retrieved.Conclusions: Users of the Clinical Study Category filters (except for Therapy) should consider combining Filter/Narrow together with Filter/Broad in their search strategy. This is particularly true when using Prognosis/Broad, as otherwise there is a substantial risk of missing potentially relevant citations.

scholarly journals Postoperative Spine Infection: Diagnosis and Management

2018 ◽  
Vol 8 (4_suppl) ◽  
pp. 37S-43S ◽  
Author(s):  
James Dowdell ◽  
Robert Brochin ◽  
Jun Kim ◽  
Samuel Overley ◽  
Jonathan Oren ◽  
...  
Keyword(s):  
Medical Subject Headings ◽  
Spine Infection ◽  
Diagnosis And Management ◽  
Reactive Protein ◽  
Mesh Terms ◽  
Deep Wound ◽  
Cochrane Database ◽  
Postoperative Spine ◽  
High Index Of Suspicion ◽  
Monitoring Treatment

Study Design: Review article. Objectives: A review of the literature on postoperative spinal infections, their diagnosis, and management. Methods: A systematic computerized Medline literature search was performed using PubMed, Cochrane Database of Systematic Reviews, and EMBASE. The electronic databases were searched for publication dates from the last 10 years. The searches were performed from Medical Subject Headings (MeSH) used by the National Library of Medicine. Specifically, MeSH terms “spine,” “infections,” “management,” and “diagnosis” were used. Results: Currently, the gold standard for diagnosis of postoperative spine infection is positive deep wound culture. Many of the current radiologic and laboratory tests can assist with the initial diagnosis and monitoring treatment response. Currently erythrocyte sedimentation rate, C-reactive protein, computed tomography scan, and magnetic resonance imaging with and without contrast are used in combination to establish diagnosis. Management of postoperative spine infection involves thorough surgical debridement and targeted antibiotic therapy. Conclusions: Postoperative spine infection is a not uncommon complication following surgery that may have devastating consequences for a patient’s short- and long-term health. A high index of suspicion is needed to make an early diagnosis.

scholarly journals Skill decay following Basic Life Support training: a systematic review protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. e051959
Author(s):  
Benjamin Stanley ◽  
Thomas Burton ◽  
Harriet Percival ◽  
Emily Beesley ◽  
Nicholas Coffin ◽  
...  
Keyword(s):  
Systematic Review ◽  
Basic Life Support ◽  
Life Support ◽  
Meta Analysis ◽  
National Curriculum ◽  
Manuscript Submission ◽  
Medical Subject Headings ◽  
Mesh Terms ◽  
Bystander Cardiopulmonary Resuscitation ◽  
The Uk

IntroductionSurvival from out of hospital cardiac arrest (OHCA) is lower in the UK than in several developed nations. Bystander cardiopulmonary resuscitation (CPR) is associated with increased rates of survival to hospital discharge following OHCA, prompting the introduction of several initiatives by the UK government to increase rates of bystander CPR, including the inclusion of Basic Life Support (BLS) teaching within the English national curriculum. While there is clear benefit in this, increasing evidence suggests poor retention of skills following BLS teaching. The aim of this systematic review is to summarise the literature regarding skill decay following BLS training, reporting particularly the time period over which this occurs, and which components of would-be rescuers’ performance of the BLS algorithm are most affected.Methods and analysisA search will be conducted to identify studies in which individuals have received BLS training and received subsequent assessment of their skills at a later date. A search strategy comprising relevant Medical Subject Headings (MeSH) terms and keywords has been devised with assistance from an experienced librarian. Relevant databases will be searched with titles, abstract and full-text review conducted independently by two reviewers. Data will be extracted from included studies by two reviewers, with meta-analysis conducted if the appropriate preconditions (such as limited heterogeneity) are met.Ethic and disseminationNo formal ethical approval is required for this systematic review. Results will be disseminated in the form of manuscript submission to a relevant journal and presentation at relevant meetings. To maximise the public’s access to this review’s findings, any scientific report will be accompanied by a lay summary posted via social media channels, and a press release disseminated to national and international news agencies.PROSPERO registration numberCRD42021237233.

Current Therapy of Diabetic Macular Edema Bevacizumab, Triamcinolone Acetonide, and Laser Photocoagulation

2019 ◽  
Vol 45 (1) ◽  
pp. 13
Author(s):  
Gladys Kusumowidagdo ◽  
Randy Sarayar ◽  
Kartika Rahayu ◽  
Gitalisa Andayani
Keyword(s):  
Macular Edema ◽  
Triamcinolone Acetonide ◽  
Diabetic Macular Edema ◽  
Systematic Reviews ◽  
Laser Photocoagulation ◽  
Meta Analysis ◽  
Intravitreal Bevacizumab ◽  
Current Therapy ◽  
Intravitreal Triamcinolone ◽  
Mesh Terms

Background: Diabetic macular edema (DME) is the main cause of visual impairment in diabetic retinopathy (DR). Current gold standard therapy of DME is macular laser photocoagulation (MPC). Growing evidences have shown benefits of intravitreal anti-VEGF agents (i.e bevacizumab) and intravitreal corticosteroids (i.e triamcinolone acetonide). Aim: To compare the visual acuity (VA) improvement of patients with DME, treated with intravitreal bevacizumab (IVB), a combination of IVB and intravitreal triamcinolone (IVB/IVT), and MPC. Method: A comprehensive PubMed® and Cochrane® databases search was conducted on May 4th, 2017 using appropriate keywords (diabetic macular edema, bevacizumab, triamcinolone, and laser photocoagulation using their MeSH terms). Studies were filtered using inclusion criterions (clinical trials, RCT, meta-analysis, systematic review, English, humans, and publication within 10 years) Results: Three studies (2 systematic reviews and 1 RCT) were found suitable. From these results, all studies showed favoring effects of IVB when compared to IVB/IVT combination and MPC in short term period (up to 6 months). However, there was no significant improvement of VA beyond this period in all groups. Conclusion: IVB appears to be superior to IVB/IVT and MPC in improving VA during 6 months follow- up period. Future systematic reviews and meta-analysis are required on the effect of IVB and MPC combination in cases of DME.

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