scholarly journals Potential of magnetic nano cellulose in biomedical applications: Recent Advances

2021 ◽  
Vol 1 (1) ◽  
pp. 32-47
Author(s):  
Anuj Kumar ◽  
Ankur Sood ◽  
Sung Soo Han

Biopolymers have attracted considerable attention in various biomedical applications. Among them, cellulose as sustainable and renewable biomass has shown potential efficacy. With the advancement in nanotechnology, a wide range of nanostructured materials have surfaced with the potential to offer substantial biomedical applications. . The progress of cellulose at the nanoscale regime (nanocelluloses) with diverse forms like cellulose nanocrystals, nanofibres and bacterial nanocellulose) has imparted remarkable properties like high aspect-ratio and high mechanical strength, and biocompatibility. The amalgamation of nanocellulose together with magnetic nanoparticles (MNC) could be explored for a synergistic effect. In this review, a brief introduction of nano cellulose , magnetic nanoparticles and the synergistic effect of MNC is described. Further, the review sheds light on the recent studies based on MNCs with their potential in the biomedical area. Finally, the review is concluded by citing the remarkable value of MNC with their futuristic applications in other fields like friction layers for triboelectric nanogenerator (TENG), energy production, hydrogen splitting, and wearable electronics.

2019 ◽  
Vol 5 (4) ◽  
pp. 66 ◽  
Author(s):  
Janja Stergar ◽  
Irena Ban ◽  
Uroš Maver

Magnetic nanoparticles became increasingly interesting in recent years as a result of their tailorable size-dependent properties, which enable their use in a wide range of applications. One of their emerging applications is biomedicine; in particular, bimetallic nickel/copper magnetic nanoparticles (NiCu MNPs) are gaining momentum as a consequence of their unique properties that are suitable for biomedicine. These characteristics include stability in various chemical environments, proven biocompatibility with various cell types, and tunable magnetic properties that can be adjusted by changing synthesis parameters. Despite the obvious potential of NiCu MNPs for biomedical applications, the general interest in their use for this purpose is rather low. Nevertheless, the steadily increasing annual number of related papers shows that increasingly more researchers in the biomedical field are studying this interesting formulation. As with other MNPs, NiCu-based formulations were examined for their application in magnetic hyperthermia (MH) as one of their main potential uses in clinics. MH is a treatment method in which cancer tissue is selectively heated through the localization of MNPs at the target site in an alternating magnetic field (AMF). This heating destroys cancer cells only since they are less equipped to withstand temperatures above 43 °C, whereas this temperature is not critical for healthy tissue. Superparamagnetic particles (e.g., NiCu MNPs) generate heat by relaxation losses under an AMF. In addition to MH in cancer treatment, which might be their most beneficial potential use in biomedicine, the properties of NiCu MNPs can be leveraged for several other applications, such as controlled drug delivery and prolonged localization at a desired target site in the body. After a short introduction that covers the general properties of NiCu MNPs, this review explores different synthesis methods, along with their main advantages and disadvantages, potential surface modification approaches, and their potential in biomedical applications, such as MH, multimodal cancer therapy, MH implants, antibacterial activity, and dentistry.


2019 ◽  
Vol 19 (11) ◽  
pp. 7369-7373 ◽  
Author(s):  
Jintang Lin

Ultraviolet (UV) detectors have a wide range of commercial applications. However, most UV light detectors require an external power source, which limits their applications as portable and/or wearable electronics. In this work, a self-powered UV detector based on triboelectric nanogenerator (TENG) technology is demonstrated. Nano-ripple zinc oxide (ZnO) film acting as both UV-sensitive and triboelectric material was synthesized by a simple sol–gel method. The self-powered UV sensor detected UV irradiation without an external power source. The open-circuit voltage of the device under UV irradiation was 130 V, which was 2.3 times higher than the output of the device in the dark. Possible operating mechanisms of the device, which is based on the contact electrification process, are described.


Author(s):  
Venkatasubramaniam S. Kalambur ◽  
Bumsoo Han ◽  
Byeong-Su Kim ◽  
T. Andrew Taton ◽  
John C. Bischof

Magnetic nanoparticles can be used for a variety of biomedical applications. They can be used in the targeted delivery of therapeutic agents, as contrast agents in MR imaging and in the hyperthermic treatment of cancers. Previous studies using these particles have not dealt with a quantitative characterization of movement and heating of these particles in biological environments. In the present study, the thermal characteristics of magnetic nanoparticles in water and collagen were investigated. In other studies, the movement of these particles in collagen in a known magnetic field was studied; infra-red (IR) imaging was used to visualize these particles in vitro. The results show that the amount of temperature rise increases with the concentration of nanoparticles regardless of the microenvironments. However, the amount of heating in collagen is significantly less than water at the same nanoparticle concentration. IR imaging can be used to visualize these particles in vitro over a wide range of concentrations of these nanoparticles.


2015 ◽  
Vol 21 (42) ◽  
pp. 6038-6054 ◽  
Author(s):  
Dragoș Gudovan ◽  
Paul Balaure ◽  
Dan Mihăiescu ◽  
Adrian Fudulu ◽  
Bogdan Purcăreanu ◽  
...  

2021 ◽  
Vol 413 (9) ◽  
pp. 2389-2406 ◽  
Author(s):  
Soumyabrata Banik ◽  
Sindhoora Kaniyala Melanthota ◽  
Arbaaz ◽  
Joel Markus Vaz ◽  
Vishak Madhwaraj Kadambalithaya ◽  
...  

AbstractSmartphone-based imaging devices (SIDs) have shown to be versatile and have a wide range of biomedical applications. With the increasing demand for high-quality medical services, technological interventions such as portable devices that can be used in remote and resource-less conditions and have an impact on quantity and quality of care. Additionally, smartphone-based devices have shown their application in the field of teleimaging, food technology, education, etc. Depending on the application and imaging capability required, the optical arrangement of the SID varies which enables them to be used in multiple setups like bright-field, fluorescence, dark-field, and multiple arrays with certain changes in their optics and illumination. This comprehensive review discusses the numerous applications and development of SIDs towards histopathological examination, detection of bacteria and viruses, food technology, and routine diagnosis. Smartphone-based devices are complemented with deep learning methods to further increase the efficiency of the devices.


Pharmaceutics ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1125
Author(s):  
Raluca Nicu ◽  
Florin Ciolacu ◽  
Diana E. Ciolacu

Nanocelluloses (NCs), with their remarkable characteristics, have proven to be one of the most promising “green” materials of our times and have received special attention from researchers in nanomaterials. A diversity of new functional materials with a wide range of biomedical applications has been designed based on the most desirable properties of NCs, such as biocompatibility, biodegradability, and their special physicochemical properties. In this context and under the pressure of rapid development of this field, it is imperative to synthesize the successes and the new requirements in a comprehensive review. The first part of this work provides a brief review of the characteristics of the NCs (cellulose nanocrystals—CNC, cellulose nanofibrils—CNF, and bacterial nanocellulose—BNC), as well as of the main functional materials based on NCs (hydrogels, nanogels, and nanocomposites). The second part presents an extensive review of research over the past five years on promising pharmaceutical and medical applications of nanocellulose-based materials, which have been discussed in three important areas: drug-delivery systems, materials for wound-healing applications, as well as tissue engineering. Finally, an in-depth assessment of the in vitro and in vivo cytotoxicity of NCs-based materials, as well as the challenges related to their biodegradability, is performed.


Nanoscale ◽  
2021 ◽  
Author(s):  
Frederik Laust Durhuus ◽  
Lau Halkier Wandall ◽  
Mathias Hoeg Boisen ◽  
Mathias Kure ◽  
Marco Beleggia ◽  
...  

Magnetically guided self-assembly of nanoparticles is a promising bottom-up method to fabricate novel materials and superstructures, such as, for example, magnetic nanoparticle clusters for biomedical applications. The existence of assembled...


Author(s):  
Francesca Persano ◽  
Svetlana Batasheva ◽  
Gölnur Fakhrullina ◽  
Giuseppe Gigli ◽  
Stefano Leporatti ◽  
...  

Inorganic materials, in particular nanoclays and silica nanoparticles, have attracted enormous attention due to their versatile and tuneable properties, making them ideal candidates for a wide range of biomedical applications, such as drug delivery.


Molecules ◽  
2020 ◽  
Vol 26 (1) ◽  
pp. 49
Author(s):  
Hélida Gomes de Oliveira Barud ◽  
Robson Rosa da Silva ◽  
Marco Antonio Costa Borges ◽  
Guillermo Raul Castro ◽  
Sidney José Lima Ribeiro ◽  
...  

Bacterial cellulose (BC) is a natural polymer that has fascinating attributes, such as biocompatibility, low cost, and ease of processing, being considered a very interesting biomaterial due to its options for moldability and combination. Thus, BC-based compounds (for example, BC/collagen, BC/gelatin, BC/fibroin, BC/chitosan, etc.) have improved properties and/or functionality, allowing for various biomedical applications, such as artificial blood vessels and microvessels, artificial skin, and wounds dressing among others. Despite the wide applicability in biomedicine and tissue engineering, there is a lack of updated scientific reports on applications related to dentistry, since BC has great potential for this. It has been used mainly in the regeneration of periodontal tissue, surgical dressings, intraoral wounds, and also in the regeneration of pulp tissue. This review describes the properties and advantages of some BC studies focused on dental and oral applications, including the design of implants, scaffolds, and wound-dressing materials, as well as carriers for drug delivery in dentistry. Aligned to the current trends and biotechnology evolutions, BC-based nanocomposites offer a great field to be explored and other novel features can be expected in relation to oral and bone tissue repair in the near future.


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