scholarly journals Anxiety impact during COVID-19: a systematic review

2021 ◽  
Vol 15 (03) ◽  
pp. 320-325
Author(s):  
Patricia Batista ◽  
Vitor Duque ◽  
Ana Luzio-Vaz ◽  
Anabela Pereira
Keyword(s):  
Systematic Review ◽  
Published Data ◽  
Inclusion Criteria ◽  
Exclusion Criteria ◽  
Cross Sectional ◽  
Future Studies ◽  
Anxiety Measurement ◽  
Meta Analyses ◽  
The Impact ◽  
Sample Methodology

Introduction: The COVID-19 epidemic has been causing serious physical, but also psychological effects in society. This systematic review sought to identify studies that describe COVID-19 related anxiety, and to understand the impact of anxiety assessment in defining strategies to be implemented in future studies. Methodology: This systematic review included cross-sectional studies with no publication year limit. It was performed a systematic search through three databases, namely, PubMed, Science Direct and Web of Science using the descriptors “COVID-19” and “anxiety”. PRISMA criteria reporting of systematic reviews and meta-analyses were applied. Eligible articles were selected in accordance with inclusion and exclusion criteria. The inclusion criteria were: research articles related with anxiety measurement during the COVID-19 outbreak; interventions to reduce anxiety; and published in English. Results: From 44 references, just four scientific articles were accepted for inclusion within this review. These studies were analyzed regarding their sample, methodology, instruments used, and its results. Conclusions: This systematic review was based on published data at the onset of the pandemic, and it could serve as a basis for the development of implementations plans to improve anxiety disorders. The importance of this theme, the implications and potential directions for future investigations will be discussed.

Adverse Effects of Natural Products: A Brief Pre-Systematic Review

2020 ◽  
Vol 01 ◽  
Author(s):  
Carla Pires ◽  
Ana Fernandes
Keyword(s):  
Systematic Review ◽  
Adverse Event ◽  
Natural Products ◽  
Adverse Events ◽  
In Vitro Study ◽  
Google Scholar ◽  
Inclusion Criteria ◽  
Exclusion Criteria ◽  
Meta Analyses

Background: Natural products are commonly used for treating health problems. These products may be associated with adverse events, which are defined as "noxious and unintended response to a medicinal product" by the European Medicine Agency. Objectives: To identify studies describing at least one adverse event (or with potential to promote an adverse event) related to the use of natural products, as well as to describe the involved product(s) and adverse event(s). Methods: A pre-systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. Keywords: "natural product(s)" and ["adverse drug reaction(s)" or "adverse effect(s)"]. Screened databases: PubMed, SciELO, DOAJ and Google Scholar. Inclusion criteria: papers describing at least one adverse event associated with the use of natural products and published between 2017 and 2019. Exclusion criteria: Repeated studies, reviews and papers written in other languages than English, Portuguese, French or Spanish. Results: 104 studies were identified (20 PubMed; 0 SciELO; 2 DOAJ; 82 Google Scholar), but only 10 were selected (4 PubMed and 6 Google Scholar): 1 in-vitro study; 2 non-clinical studies, 1 study reporting in-vitro and clinical data and 5 studies were cases reports. Globally, 997 reports of adverse drug reactions with natural products were identified, mainly non-severe cases. Conclusion: Since a limited number of studies was found, we conclude that adverse events due to natural products may be underreported, or natural products may have a good safety profile. This review contributes for assuring the safety of natural products consumers, by evaluating the knowledge/information on the potential adverse events and interactions of these products.

scholarly journals Mental Health in Health Students during Coronavirus Disease-19: Systematic Review

2021 ◽  
Vol 9 (F) ◽  
pp. 205-210
Author(s):  
Agus Purnama ◽  
Susaldi Susaldi ◽  
Halma Zahro Mukhlida ◽  
Hilma Hasro Maulida ◽  
Nyimas Heny Purwati
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Mental Health Problems ◽  
Cross Sectional Study ◽  
Poor Mental Health ◽  
Inclusion Criteria ◽  
Letters To The Editor ◽  
Exclusion Criteria ◽  
Cross Sectional ◽  
Psychological Conditions

Purpose: This study aims to examine the description of mental health characteristics of health students who conducted studies during the COVID-19 pandemic. Methods: The design of this study is to use a systematic review approach by collecting several articles from a database that has been selected consisting of Springer. , ScienceDirect and ProQuest with articles published in 2020. Search for articles was carried out by entering the keyword "mental health AND student AND COVID-19". The search for this article was limited to inclusion criteria and exclusion criteria. The inclusion criteria in this study were health students who were still conducting studies during the COVID-19 pandemic and a cross-sectional study design, while the exclusion criteria were non-health students, only abstracts and books, and letters to the editor. Results: After a search on the selected database, the results are 677 Springer articles, 554 direct articles, and 1348 ProQuest articles. 11 were removed for duplicates, 444 full texts were reviewed and 6 articles matched inclusion and exclusion criteria. The results of the 6 articles that were reviewed showed that the majority of health students reported mental health problems such as anxiety, depression, stress, and another emotional status. Where moderate and severe levels of anxiety were experienced by some Health students who carried out education during the Covid-19 pandemic. Conclusion: The COVID-19 pandemic has an impact on psychological conditions, especially on health students who are carrying out their education. Students report poor mental health conditions while carrying out home education by learning online during the COVID-19 pandemic.

scholarly journals Artificial Intelligence for Caregivers of Persons With Alzheimer’s Disease and Related Dementias: Systematic Literature Review (Preprint)

2020 ◽  
Author(s):  
Bo Xie ◽  
Cui Tao ◽  
Juan Li ◽  
Robin C Hilsabeck ◽  
Alyssa Aguirre
Keyword(s):  
Artificial Intelligence ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Digital Library ◽  
Full Text ◽  
Interdisciplinary Collaboration ◽  
Exclusion Criteria ◽  
Cross Sectional ◽  
Meta Analyses ◽  
The Impact

BACKGROUND Artificial intelligence (AI) has great potential for improving the care of persons with Alzheimer’s disease and related dementias (ADRD) and the quality of life of their family caregivers. To date, however, systematic review of the literature on the impact of AI on ADRD management has been lacking. OBJECTIVE This paper aims to (1) identify and examine literature on AI that provides information to facilitate ADRD management by caregivers of individuals diagnosed with ADRD and (2) identify gaps in the literature that suggest future directions for research. METHODS Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for conducting systematic literature reviews, during August and September 2019, we performed 3 rounds of selection. First, we searched predetermined keywords in PubMed, Cumulative Index to Nursing and Allied Health Literature Plus with Full Text, PsycINFO, IEEE Xplore Digital Library, and the ACM Digital Library. This step generated 113 nonduplicate results. Next, we screened the titles and abstracts of the 113 papers according to inclusion and exclusion criteria, after which 52 papers were excluded and 61 remained. Finally, we screened the full text of the remaining papers to ensure that they met the inclusion or exclusion criteria; 31 papers were excluded, leaving a final sample of 30 papers for analysis. RESULTS Of the 30 papers, 20 reported studies that focused on using AI to assist in activities of daily living. A limited number of specific daily activities were targeted. The studies’ aims suggested three major purposes: (1) to test the feasibility, usability, or perceptions of prototype AI technology; (2) to generate preliminary data on the technology’s performance (primarily accuracy in detecting target events, such as falls); and (3) to understand user needs and preferences for the design and functionality of to-be-developed technology. The majority of the studies were qualitative, with interviews, focus groups, and observation being their most common methods. Cross-sectional surveys were also common, but with small convenience samples. Sample sizes ranged from 6 to 106, with the vast majority on the low end. The majority of the studies were descriptive, exploratory, and lacking theoretical guidance. Many studies reported positive outcomes in favor of their AI technology’s feasibility and satisfaction; some studies reported mixed results on these measures. Performance of the technology varied widely across tasks. CONCLUSIONS These findings call for more systematic designs and evaluations of the feasibility and efficacy of AI-based interventions for caregivers of people with ADRD. These gaps in the research would be best addressed through interdisciplinary collaboration, incorporating complementary expertise from the health sciences and computer science/engineering–related fields.

scholarly journals Prevalence of Intracranial Aneurysm in Patients with Aortopathy: A Systematic Review with Meta-Analyses

2020 ◽  
Vol 22 (1) ◽  
pp. 76-86 ◽  
Author(s):  
Xinyu Yu ◽  
Liangtao Xia ◽  
Qingqing Jiang ◽  
Yupeng Wei ◽  
Xiang Wei ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Intracranial Aneurysm ◽  
Random Effect ◽  
Aortic Disease ◽  
Anatomical Location ◽  
Cross Sectional ◽  
Increased Risk ◽  
Meta Analyses ◽  
The Impact

Background and Purpose Patients with aortic disease might have an increased risk of intracranial aneurysm (IA). We conducted this research to assess the prevalence of IA in patients with aortopathy, considering the impact of gender, age, and cardiovascular risk factors.Methods We searched PubMed and Scopus from inception to August 2019 for epidemiological studies reporting the prevalence of IA in patients with aortopathy. Random-effect meta-analyses were performed to calculate the overall prevalence, and the effect of risk factors on the prevalence was also evaluated. Anatomical location of IAs in patients suffered from distinct aortic disease was extracted and further analyzed.Results Thirteen cross-sectional studies involving 4,041 participants were included in this systematic review. We reported an estimated prevalence of 12% (95% confidence interval [CI], 9% to 14%) of IA in patients with aortopathy. The pooled prevalence of IA in patients with bicuspid aortic valve, coarctation of the aorta, aortic aneurysm, and aortic dissection was 8% (95% CI, 6% to 10%), 10% (95% CI, 7% to 14%), 12% (95% CI, 9% to 15%), and 23% (95% CI, 12% to 34%), respectively. Gender (female) and smoking are risk factors related to an increased risk of IA. The anatomical distribution of IAs was heterogeneously between participants with different aortic disease.Conclusions According to current epidemiological evidence, the prevalence of IA in patients with aortic disease is quadrupled compared to that in the general population, which suggests that an early IA screening should be considered among patients with aortic disease for timely diagnosis and treatment of IA.

scholarly journals Prenatal maternal stress and risk of neurodevelopmental disorders in the offspring: A systematic review and meta-analysis protocol

2018 ◽  
Vol 1 ◽  
pp. 15
Author(s):  
Nicla Manzari ◽  
Karen Matvienko-Sikar ◽  
Franco Baldoni ◽  
Gerard W. O'Keeffe ◽  
Ali S. Khashan
Keyword(s):  
Systematic Review ◽  
Maternal Stress ◽  
Data Extraction ◽  
Meta Analysis ◽  
Autism Spectrum ◽  
Prenatal Maternal Stress ◽  
Cross Sectional ◽  
Increased Risk ◽  
Meta Analyses ◽  
The Impact

Background: Prenatal maternal stress (PNMS) is defined as the experience of significant levels of prenatal stress, depression or anxiety during pregnancy. PNMS has been associated with increased risk of autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD) in exposed offspring. However, these findings are inconsistent and other studies found no association, meaning a clear consensus on the impact of PNMS on ASD and ADHD risk is required. The purpose of this systematic review and meta-analysis is to summarize and critically review the existing literature on the effects of PNMS on ASD and ADHD risk. Methods: Electronic databases (PubMed, PsycINFO, Web of Science, Scopus and EMBASE) will be searched for articles following a detailed search strategy. We will include cohort, case-control and cross-sectional studies that assessed maternal exposure to psychological and/or environmental stress and had ASD or ADHD as an outcome. Two reviewers will independently screen the titles, abstracts and full articles to identify eligible studies. We will use a standardised data extraction form for extracting data and a bias classification tool for assessing study quality. This systematic review will be reported according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA). The generic inverse variance method will be used if possible to perform meta-analyses. Ethics and dissemination: Ethical approval is not required for this study because it will not involve the conduct or inclusion of any experimental or personal data that would require informed consent.  The systematic review will be disseminated in peer-reviewed journals. PROSPERO registration number: CRD42018084222.

scholarly journals Pathophysiological and Genetic Aspects of Vascular Calcification

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Luis Fernando Escobar Guzman ◽  
Cristian Andres Escobar Guzman ◽  
Neuza Helena Moreira Lopes
Keyword(s):  
Systematic Review ◽  
Vascular Calcification ◽  
Genetic Factors ◽  
Case Control ◽  
Inclusion Criteria ◽  
Exclusion Criteria ◽  
Cross Sectional ◽  
Prospective Cohort Studies ◽  
Chemical Mediators

Recent evidence suggests that vascular calcification is an independent cardiovascular risk factor (CRF) of morbidity and mortality. New studies point out the existence of a complex physiopathological mechanism that involves inflammation, oxidation, the release of chemical mediators, and genetic factors that promote the osteochondrogenic differentiation of vascular smooth muscle cells (VSMC). This review will evaluate the main mechanisms involved in the pathophysiology and genetics modulation of the process of vascular calcification. Objective. A systematic review of the pathophysiology factors involved in vascular calcification and its genetic influence was performed. Methods. A systematic review was conducted in the Medline and PubMed databases and were searched for studies concerning vascular calcification using the keywords and studies published until 2020/01 in English. Inclusion Criteria. Studies in vitro, animal models, and humans. These include cohort (both retrospective and prospective cohort studies), case-control, cross-sectional, and systematic reviews. Exclusion Criteria. Studies before 2003 of the existing literature.

scholarly journals Prevalence of acute liver injury and hypertransaminemia in patients with COVID-19: a protocol for a systematic review

BMJ Open ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. e040517
Author(s):  
Gang Li ◽  
Yongxing Xu ◽  
Yi Tian Yang ◽  
Peng Fei Liu
Keyword(s):  
Systematic Review ◽  
Liver Injury ◽  
Acute Liver Injury ◽  
Epidemiological Data ◽  
Risk Of Bias ◽  
Published Data ◽  
Language Restriction ◽  
Ethical Approval ◽  
Meta Analyses ◽  
The Impact

IntroductionCOVID-19 has spread rapidly in China and around the world. Published studies have revealed that some patients with COVID-19 had abnormal liver function in laboratory tests. However, the results were inconsistent and the analysis of epidemiological data stratified by the severity of COVID-19 was not available in previous meta-analyses. Furthermore, these meta-analyses were suspected of overestimating the incidence of liver injury in patients with COVID-19 because some studies considered transaminase elevation as liver injury, which might partially result from cardiac and muscle injury. This systematic review aims to enrol published literatures related to COVID-19 without language restriction, analyse the data based on the severity of the COVID-19 and explore the impact of varied definitions of liver injury on the incidence of liver injury.Methods and analysisWe have conducted a preliminary search on PubMed and Excerpta Medica Database on 13 April 2020, for the studies published after December 2019 on the prevalence of acute liver injury and hypertransaminemia in patients with COVID-19. Two reviewers will independently screen studies, extract data and assess the risk of bias. We will estimate the pooled incidence of hypertransaminemia and acute liver injury in patients with COVID-19 by using the random-effects model. The I² test will be used to identify the extent of heterogeneity. Publication bias will be assessed by funnel plot and performing the Begg’s and Egger’s test if adequate studies are available. We will perform a risk of bias assessment using the Joanna Briggs Institute’s critical appraisal checklist.Ethics and disseminationSince this study will be based on the published data, it does not require ethical approval. The final results of this study will be published in a peer-reviewed journal.PROSPERO registration numberCRD42020179462.

Impact of trainee involvement in esophagectomy on clinical outcomes: a narrative systematic review of the literature

2019 ◽  
Vol 32 (10) ◽  
pp. 1-8
Author(s):  
P Prasad ◽  
M Navidi ◽  
A Immanuel ◽  
S M Griffin OBE ◽  
A W Phillips
Keyword(s):  
Systematic Review ◽  
Clinical Outcomes ◽  
Meta Analysis ◽  
Neoadjuvant Treatment ◽  
Length Of Hospital Stay ◽  
High Volume ◽  
Cochrane Library ◽  
Published Data ◽  
Meta Analyses ◽  
The Impact

SUMMARY Changes in the structure of surgical training have affected trainees’ operative experience. Performing an esophagectomy is being increasingly viewed as a complex technical skill attained after completion of the routine training pathway. This systematic review aimed to identify all studies analyzing the impact of trainee involvement in esophagectomy on clinical outcomes. A search of the major reference databases (Cochrane Library, MEDLINE, EMBASE) was performed with no time limits up to the date of the search (November 2017). Results were screened in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and study quality assessed using the MINORS (Methodological Index for Non-Randomized Studies) criteria. Four studies that included a total of 42 trainees and 16 consultants were identified, which assessed trainee involvement in open esophagogastric resectional surgery. A total of 1109 patients underwent upper gastrointestinal procedures, of whom 904 patients underwent an esophagectomy. Preoperative characteristics, histology, neoadjuvant treatment, and overall length of hospital stay were comparable between groups. One study found higher rates of anastomotic leaks in procedures primarily performed by trainees as compared to consultants (P < 0.01)—this did not affect overall morbidity or survival; however, overall anastomotic leak rates from the published data were 10.4% (trainee) versus 6.3% (trainer) (P = 0.10). A meta-analysis could not be performed due to the heterogeneity of data. The median MINORS score for the included studies was 13 (range 11–15). This study demonstrates that training can be achieved with excellent results in high-volume centers. This has important implications on the consent process and training delivered, as patients wish to be aware of the risks involved with surgery and can be reassured that appropriately supervised trainee involvement will not adversely affect outcomes.

scholarly journals The Impact of COVID-19 and the Pandemic on Tinnitus: A Systematic Review

2021 ◽  
Vol 10 (13) ◽  
pp. 2763
Author(s):  
Eldre Beukes ◽  
Alyssa Jade Ulep ◽  
Taylor Eubank ◽  
Vinaya Manchaiah
Keyword(s):  
Case Series ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Design Studies ◽  
Impact Studies ◽  
Post Test ◽  
Disease Impact ◽  
Cross Sectional Studies ◽  
Meta Analyses ◽  
The Impact

This review aimed to systematically review what has been published regarding tinnitus during the coronavirus disease 2019 (COVID-19) pandemic up to March 2021 by performing both narrative and quantitative meta-analyses. Of the 181 records identified, 33 met the inclusion criteria, which generally had a fair risk of overall bias. In the included, 28 studies focused on the impact of the COVID-19 virus on tinnitus and 5 studies focused on the impact of the pandemic on tinnitus. From the studies identifying the impact of COVID-19 on tinnitus, there were 17 cross-sectional studies (n = 8913) and 11 case series or case report studies (n = 35). There were 2 cross-sectional studies (n = 3232) and 3 pre-post-test design studies (n = 326) focusing on the impact of the pandemic on tinnitus. No consistent patterns were found regarding the presentation of the tinnitus or additional factors that could have tinnitus developing in the disease impact studies. For the pandemic impact studies, the associated stress and anxiety of the pandemic were consistently suggested to contribute to tinnitus experiences. The pooled estimated prevalence of tinnitus post COVID-19 was 8% (CI: 5 to 13%). Medical professionals should be aware that tinnitus might be more problematic following the pandemic or after having COVID-19.

scholarly journals Smartphone Addiction and Associated Health Outcomes in Adult Populations: A Systematic Review

2021 ◽  
Vol 18 (22) ◽  
pp. 12257
Author(s):  
Zubair Ahmed Ratan ◽  
Anne-Maree Parrish ◽  
Sojib Bin Zaman ◽  
Mohammad Saud Alotaibi ◽  
Hassan Hosseinzadeh
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Health Outcomes ◽  
Mental Health Outcomes ◽  
Smartphone Addiction ◽  
Inclusion Criteria ◽  
Physical And Mental Health ◽  
Cross Sectional ◽  
Wide Range ◽  
The Impact

Background: Smartphones play a critical role in increasing human–machine interactions, with many advantages. However, the growing popularity of smartphone use has led to smartphone overuse and addiction. This review aims to systematically investigate the impact of smartphone addiction on health outcomes. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used to carry out the systematic review. Five electronic databases including Medline, Web of Science, PsycINFO, PubMed, and Scopus were searched to identify eligible studies. Eligible studies were screened against predetermined inclusion criteria and data were extracted according to the review questions. This review is registered in PROSPERO (CRD42020181404). The quality of the articles was assessed using the National Institutes of Health (NIH) Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. Results: A total of 27 of 2550 articles met the inclusion criteria. All of the studies were cross-sectional and focused on physical, mental, and neurological health outcomes. The majority of the studies focused on mental health outcomes and consistent associations were observed between smartphone addiction and several mental health outcomes. Anxiety and depression were commonly found to mediate mental health problems. A wide range of physical health sequelae was also associated with smartphone addiction. Furthermore, there was an association between smartphone addiction and neurological disorders. Conclusions: Our findings suggest that there are consistent associations between smartphone addiction and physical and mental health, especially mental health. Social awareness campaigns about smartphone addiction and its impact on physical and mental health are needed. Further studies, especially randomized controlled trials, are warranted to validate the impacts of smartphone addiction.

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