scholarly journals Effectiveness of a case management model in newly treated smear-positive pulmonary tuberculosis patients

2021 ◽  
Vol 15 (11) ◽  
pp. 1670-1676
Author(s):  
YanLing Li ◽  
Ying Wang ◽  
GaiJing Wang ◽  
YiLin Wang ◽  
YanQing Tian ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Case Management ◽  
Conversion Rate ◽  
Management Mode ◽  
Control Group ◽  
Tuberculosis Patients ◽  
Smear Positive Pulmonary Tuberculosis ◽  
Experimental Group ◽  
Knowledge Attitude And Practice ◽  
Negative Conversion

Introduction: To investigate the effectiveness of the case management mode on the application of smear-positive pulmonary tuberculosis patients. Methodology: This was a randomized control trial. A total of 70 newly diagnosed smear-positive pulmonary tuberculosis patients were recruited and been randomly divided into experimental group and control group, with 35 participants in each group. In the experimental group, patients received the tuberculosis case management mode based on the conventional management mode. In the control group, patients received the routine management mode. We compared the knowledge, attitude, and practice score; sputum-negative conversion rate, effective imaging rate of the two groups at the time of initial admission, discharge, and one month after discharge. Results: The results showed that there was no significant difference in baseline data between the two groups (p > 0.05); at the time of discharge and one month after discharge, the knowledge, belief, behavior, sputum-negative conversion rate, and imaging examination effective rate of the experimental group were higher than those of the control group (p < 0.05). Conclusions: The case management mode can improve the knowledge, attitude, and practice level; sputum-negative conversion rate; and imaging efficiency of newly treated smear-positive pulmonary tuberculosis patients.

scholarly journals Sputum Smears Conversion in Daily Versus Intermittent Treatment Regimen in New Sputum Smear Positive Pulmonary Tuberculosis Patients - A Retrospective Study

2021 ◽  
Vol 10 (42) ◽  
pp. 3617-3622
Author(s):  
Dhondiba Haribhau Bhise
Keyword(s):  
Pulmonary Tuberculosis ◽  
Treatment Regimen ◽  
Sputum Smear ◽  
Patient Death ◽  
Continuation Phase ◽  
Intensive Phase ◽  
Tuberculosis Patients ◽  
National Tuberculosis ◽  
Smear Positive Pulmonary Tuberculosis ◽  
Negative Conversion

BACKGROUND Sputum smear conversion is the negative conversion of the sputum smear at the end of the second month of treatment regimen under the National Tuberculosis Elimination Program (NTEP). When the acid-fast bacillus (AFB) smear comes negative at the end of an intensive phase, the treatment regimen can shift to the continuation phase that indicates bacillary load is a minimum. Although some authors consider the conversion of cultures when the AFB smear is negative, two potent drugs in the continuation phase are sufficient to kill the remaining bacilli. The drug that can kill bacteria in the first 2 days of treatment is called early bactericidal activity (EBA). This can be assessed by the percentage of negative conversion of cultures at the end of the intensive phase of the treatment regimen. EBA is very essential because it reduces the transmission in the community and chances of patient death. When the purpose is to kill as many bacilli as possible in the first few days and weeks of treatment, it is very important to include bactericidal drugs in the treatment regimen so that it reduces the chances of patient death and infectiousness and the negative conversion of the cultures after 2-month treatment regimen is an indication of the bactericidal capacity of the drug. The purpose of this study was to compare sputum smear conversion in daily versus intermittent treatment regimens in diagnosed cases of new sputum smear-positive pulmonary tuberculosis patients. METHODS This retrospective observational study was carried out in the Department of Respiratory medicine and nodal drug resistance tuberculosis centre (DR-TB) at the Government medical college and hospital, Akola. In this study, a total of 120 new patients were taken. 60 patients were given daily and intermittent regimens respectively under NTEP. RESULTS Out of 120 patients, 56 (93.33 %) patients in intermittent and 53 (88.33 %) patients in daily regimen were sputum smear-negative at the end of 2nd month (intensive phase) and at the end of 6th month (continuation phase). 1 patient (1.6 %) remained sputum smear-positive after the intensive phase. That patient was given 1 month of extension of anti-tuberculosis treatment (AKT) in the intensive phase and the patient became sputum negative after 1 month of extension. CONCLUSIONS It was concluded in this study, daily regimens and intermittent regimens were equally effective in negative conversion of the sputum smear at the end of the intensive phase and the end of the continuation phase. Negative conversion of the sputum smear is quite important because the bacillary load will be so low at the end of 2nd month that reduces the chances of patient death and transmission in the community. KEY WORDS Pulmonary Tuberculosis (PTB), Drug-Resistant TB (DR-TB), National Tuberculosis Programme (NTP), Revised National TB Control Program (RNTCP), Intensive Phase (IP), continuation Phase (CP), National Tuberculosis Elimination Program (NTEP).

scholarly journals Analysis of the Effect of Pantoprazole and Omeprazole on Pain Relief in Patients with Gastric Ulcer

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Minghui Xiao ◽  
Jie Liu ◽  
Jianping Hui
Keyword(s):  
Helicobacter Pylori ◽  
Gastric Ulcer ◽  
Pain Relief ◽  
Recurrence Rate ◽  
Conversion Rate ◽  
Adverse Reactions ◽  
Effective Rate ◽  
Control Group ◽  
Experimental Group ◽  
Negative Conversion

Objective: To analyze the effect of pantoprazole and omeprazole in the treatment of patients with gastric ulcer. Methods: The treatment effect, recurrence rate, helicobacter pylori negative conversion rate, adverse reaction status and pain relief time of the two groups were compared. Results: The total effective rate of the experimental group (97.78%, 44 / 45) was higher than that of the control group (84.44%, 38 / 45), P < 0.05;The recurrence rate (4.44%, 2 / 45) and Helicobacter pylori negative conversion rate (95.56%, 43 / 45) of the experimental group were significantly higher than those of the control group (P < 0.05); The incidence of adverse reactions in the experimental group (11.11%, 5 / 45) was lower than that in the control group (15.56%, 7 / 45) (P > 0.05);The pain relief time of the experimental group was (2.24 ± 1.16) d, which was shorter than that of the control group (P < 0.05). Conclusion: In the process of clinical treatment of gastric ulcer, pantoprazole has significant curative effect and low recurrence rate, which can eradicate Helicobacter pylori as soon as possible, shorten the pain time and make the treatment safer.

scholarly journals Treatment outcome in new smear positive pulmonary tuberculosis patients with and without immunosuppression on RNTCP regimen: a comparative observational study

2017 ◽  
Vol 5 (2) ◽  
pp. 384 ◽  
Author(s):  
Radhika Muttath ◽  
Mekkattukkunnel Andrews ◽  
Dinesa Prabhu
Keyword(s):  
Treatment Outcome ◽  
Pulmonary Tuberculosis ◽  
Steroid Therapy ◽  
Group Treatment ◽  
Control Group ◽  
Sputum Smear ◽  
Diabetic Patients ◽  
Hiv Patients ◽  
Tuberculosis Patients ◽  
Smear Positive Pulmonary Tuberculosis

Background: Immune status of a patient influences the susceptibility, clinical presentation of tuberculosis and its treatment outcome. Some of the most common conditions associated with immune deficiency includes, human immunodeficiency virus (HIV) infection, diabetes and chronic steroid therapy for any underlying diseases.Methods: A cohort study, enrolled patients with tuberculosis alone (n=51) and those with tuberculosis and immunosuppressed state (patients with HIV, diabetes and those on steroid therapy, n=97).Results: All patients received Directly Observed Treatment Short course (DOTS) regimen implemented through RNTCP. Among the immunosuppressed patients, 32 were HIV patients, 45 of them were diabetic and 20 received chronic steroid therapy. All immunocompetent patients (control) were totally cured but 62.5% and 88.9% of HIV and diabetic patients in the immunosuppressed group were cured. Mortality was high in the immunosuppressed group (18.75% in HIV, and 11.11% in diabetic group). The grade of sputum smear had significant influence on the treatment outcome after adjusting for death and default (p>0.05). After intensive phase, the smear conversion rate were 86.27% in the control group,37.5% in the HIV patients, 22.22% in diabetics and 55% among chronic steroid use. The mortality and cure rate among those who received treatment for diabetes mellitus is comparable with that of immunocompetent group. Treatment prolongation was required for patients in the immunosuppressed group (62.5% in HIV group, 77.7% in diabetes group and 45% in chronic steroid users group).Conclusions: Immunosuppression was a risk factor for increased morbidity and mortality among new smear positive pulmonary tuberculosis patients. Prolonged DOTS regimen requires long-term close follow-up of patients who are immunocompromised.

scholarly journals Effect of Case Management Nursing Service on Compliance Behavior and Quality of Life of Patients with Pulmonary Tuberculosis

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Jin Jiao ◽  
Yanling Li ◽  
Hui Wang
Keyword(s):  
Quality Of Life ◽  
Pulmonary Tuberculosis ◽  
Case Management ◽  
Compliance Rate ◽  
Control Group ◽  
Study Group ◽  
Nursing Service ◽  
Tuberculosis Patients ◽  
Compliance Behavior

Objective: To explore the effect of case management nursing service on compliance behavior and quality of life of patients with pulmonary tuberculosis. Methods: 69 cases of pulmonary tuberculosis patients in our hospital from September 2019 to August 2020 were selected as the research objects. The 69 patients were divided into study group (35 cases) and control group (34 cases). The compliance behavior, quality of life and nursing satisfaction of pulmonary tuberculosis patients were studied and analyzed. Results: The compliance rate of the control group was 82.35%, and that of the study group was 97.14%;The quality of life in the control group was [61.32 ± 7.66], which was significantly lower than that in the study group [71.12 ± 7.23];The satisfaction rate of the study group was 97.14%, which was significantly higher than 73.53% of the control group. Conclusion: In the treatment of tuberculosis patients, the use of case management nursing service can effectively improve the quality of life of patients, improve the compliance behavior of patients, and improve the treatment effect of patients, which is worthy of promotion.

Determination some Immunological Aspects in Pulmonary Tuberculosis Patients in Qadisiyah Province

2018 ◽  
Vol 9 (2) ◽  
Author(s):  
Syoof Khowman Alramahy ◽  
Akram Hadi Hamza
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Pulmonary Tuberculosis ◽  
Statistical Difference ◽  
Positive Culture ◽  
Control Group ◽  
Tuberculosis Patients ◽  
Significant Difference ◽  
Lowenstein Jensen ◽  
The Mean ◽  
Igg Level

This study was carried out to study of some immunological aspects among the pulmonary Tuberculosis patients infected with causative agent, Mycobacterium tuberculosis. A Total of 200 sputum samples were collected from patients attending the consultant Clinic for Chest and Respiratory disease center, Diwaniya. Control group (No=15) also included. According to acid fast stain of sputum, the patients were classified as positive (No=91,45.5%) and negative (No=109,54.5, Lowenstein Jensen medium used for the cultivation of samples, on which 70% of sputum samples where positive culture for this microorganism. The grown microorganism were identified as M. tuberculosis, based on positive A.F.B, Niacin producers ,negative for catlase at 68c. The mean IgG level was l184.053±76.684 mg/100 ml in tuberculosis group compared with 1016.533 ± 44.882 mg/100ml in control group, rendering the statistical difference significant. For IgA and IgM levels, they were at mean of 315.880±38.552 mg/100 ml and 119.527±8.464 mg/100 ml in control group compared with 396.358±38.776 mg/100 ml and 134.207±11.696 mg/100 ml in patients group respectively with significant difference

scholarly journals Research on the Influence of the Light and Sexing on Growth Performance and Slaughter Results at Young Quails from Mixed Baloteşti Population of Eggs-Meat

2017 ◽  
Vol 74 (1) ◽  
pp. 15
Author(s):  
Lucian IONITA ◽  
Elena POPESCU-MICLOSANU ◽  
George NICA ◽  
Cornel Octavian PANA
Keyword(s):  
Weight Gain ◽  
Growth Performance ◽  
Conversion Rate ◽  
Live Weight ◽  
Control Group ◽  
Average Weight ◽  
Feed Conversion ◽  
Feed Conversion Rate ◽  
Average Weight Gain ◽  
Experimental Group

The purposes of determining the influence of the light and sexing on growth performance and slaughter results atyoung quails from Balotesti population, was organized an experiment on 150 quails, betwen age of 28 and 70 days. The chicks were divided into two groups (control and experimental), and growth and slaughter performance were determined separately by sex. Have studied 2 lighting programs, a program of continous lighting with photoperiod duration of 16 hours (16 L + 8 N, control group) and a program with lighting with asymetric hours intervals with photoperiod duration of 16 hours (10L+2N+6L+6N, experimental group).Males and females from the experimental group were recorded average performance of growth high during the period 28 - 70 days. Live weight at age of 70 days was higher with 7.54 %, average weight gain was higher with 14.86 % and feed conversion rate was lower with 13.51 % at males from experimental group compared to males from the control group. Also, the live weight at the age of 70 days was higher with 18.09 %; average weight gain was higher with 35.12 %, while feed conversion rate was reduced with 30.08 % on females from the experimental group compared to females from the control group.The results of the slaughter at 70 days were superior in the caseof females from the both groups versus males. The average weight of the carcase was higher with 17.53 % in case of the females than that of males from the experimental group, and the carcase yield was 65.37 % at the females and 65.56 % for males. Also, the average weight of the carcase was higher with 5.08 % in case of females compared to that males from the control group, and the carcase yield was 64.20 % to females 66.70 % on males.Superior results recorded in the case of females and males from the experimental group recommended the program of lighting with asymmetric hours intervals in the growth of youth quail. Also, the higher slaughter results recorded in the case of females of the two groups recommended them in the meat production through a broiler of quail that combine advantages in the production of both males and females. 

scholarly journals Factors Influencing Sputum Conversion among Smear-Positive Pulmonary Tuberculosis Patients in Morocco

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Khalid Bouti ◽  
Mohammed Aharmim ◽  
Karima Marc ◽  
Mouna Soualhi ◽  
Rachida Zahraoui ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Stepwise Regression ◽  
Control Measures ◽  
Sputum Smear ◽  
Tuberculosis Patients ◽  
Infection Control Measures ◽  
Factors Influencing ◽  
Smear Positive Pulmonary Tuberculosis ◽  
Sputum Conversion ◽  
A Prospective Study

Background. Sputum smear-positive pulmonary tuberculosis patients expel infectious viable bacilli for a period following the commencement of treatment. Objective. To determine the time to sputum smear conversion and study the factors influencing it. Design. A prospective study was undertaken at our hospital in Rabat over a six-month period on a cohort of 119 sputum smear positive patients. Patients were followed up fortnightly. At each followup, specimens were collected and processed for microscopy using standard protocol. Results. 96.6% of our patients completed the study (4 deaths). Sputum conversion rate was 42% after two weeks, 73% after one month, and 95% after two months. Univariate and stepwise regression analysis showed that patients who had high smear grading, miliary, and bilateral radiologic lesions were more likely to undergo delayed sputum conversion (P<0.05). Other factors were thought to influence sputum conversion but were not statistically proven in our study. Conclusion. Since viable bacilli continue to be expelled for up to two months, infection control measures should be maintained for such a time. Patients with high smear grading, miliary, and bilateral radiologic lesions need to be monitored more closely.

scholarly journals Relationship Physical Environmental in Bedroom and Familyroom with New Cases of Smear Positive Pulmonary Tuberculosis in the work area of Puskesmas Songgon Banyuwangi

2018 ◽  
pp. 141-153
Author(s):  
Ayudita Ismiyanti ◽  
Corie Indria Prasasti ◽  
Erni Astutik
Keyword(s):  
Pulmonary Tuberculosis ◽  
Simple Random Sampling ◽  
Control Group ◽  
Case Group ◽  
Chi Square ◽  
The People ◽  
Work Area ◽  
Smear Positive Pulmonary Tuberculosis ◽  
Chi Square Analysis ◽  
Physical Environmental Factors

Tuberculosis (TB) is a contagious infectious disease due to the bacterium Mycobacterium tuberculosis. Until now, TB disease is still one of the world's health problems and its existence is often linked to environmental problems. This study aims to analyze the physical environmental factors of the house, especially in the bedroom and familiy room associated with smear positive pulmonary tuberculosis new cases in the work area of ​​Puskesmas Songgon Banyuwangi. The design of this research is case control, with the comparison of case:control is 1: 2. A total of 15 people from the case group were taken from SITT (Integrated Tuberculosis Information System) Puskesmas Songgon Banyuwangi and selected using simple random sampling method, while 30 control group were neighbors of case group matching based on gender. Dependent variables is new cases of smear positive pulmonary tuberculosis in the work area of ​​Puskesmas Songgon Banyuwangi and independent variables include ventilation, temperature, humidity, and lighting in bedroom and famiy room. The result of chi square analysis showed that there was a significant correlation between bedroom lighting (OR=4,667; 95%CI=1,237-17,600; p=0,043) and family room lighting (OR=4,571; 95%CI=1,182-17,678; p=0,039) with a new case of smear positive pulmonary TB in the work area of Puskesmas Songgon Banyuwangi. Therefore, the need for awareness to the community, especially the people with pulmonary tuberculosis, by health personnel Pukesmas Songgon Banyuwangi about the importance of keeping the home environment to stay healthy, one of them by allowing air to change and sunlight can enter the house by opening the window in every room house in the morning, and replace the brick tile with glass tile.   Keywords : Pulmonary Tuberculosis, smear, lighting, bedroom, family room

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