scholarly journals Seroprevalence of human cysticercosis and its associated risk factors among humans in areas of Kaduna metropolis, Nigeria

2015 ◽  
Vol 9 (08) ◽  
pp. 799-805 ◽  
Author(s):  
Agnes Uregwu Edia-Asuke ◽  
Helen I Inabo ◽  
Samson Mukaratirwa ◽  
Veronica J Umoh ◽  
Clement MZ Whong ◽  
...  

Introduction: Taenia solium cysticercosis is considered an emerging parasitic zoonosis of global importance due to its impact on both agriculture and public health in developing countries. Epidemiological information on human cysticercosis is limited in Nigeria. This study was conducted to determine the seroprevalence of human cysticercosis in areas of Kaduna metropolis, Nigeria, where small-holder pig farming is practiced. Methodology: A cross-sectional survey was conducted in Kaduna South and Chikun Local Government Areas of Kaduna metropolis, which are widely involved in small-holder pig farming and pork consumption. A total of 300 human sera were collected and tested for the presence of IgG antibodies to T. solium using an enzyme-linked immunosorbent assay (ELISA) technique. A structured questionnaire was used to identify risk factors in the population and was administered to the study population. Results: A total of 43 of 300 sera tested positive to IgG antibodies, indicating a cysticercosis prevalence of 14.3%. Method of pork preparation and history of epilepsy were found to be strongly associated with seropositivity. Epileptics in this study were two times more likely to be seropositive than non-epileptics. A large proportion (74.0%) of the population had very poor knowledge of cysticercosis, and knowledge of cysticercosis was strongly associated with method of pork preparation and respondents’ occupations. Conclusions: A high seroprevalence of human cysticercosis was found in Kaduna South and Chikun Local Government Areas. The main risk and behavioral factors contributing to the high prevalence include poor knowledge of cysticercosis and lack of knowledge on proper pork preparation methods.

2019 ◽  
Vol 13 (03) ◽  
pp. 233-239
Author(s):  
Hamish Mohammed ◽  
Mary H Hayden ◽  
Elise Lee ◽  
Luis M Santiago ◽  
Rosina C Krecek ◽  
...  

Introduction: After a large outbreak of dengue virus (DENV) serotype-3 in Saint Kitts and Nevis (SKN) in 2008, we performed a cross-sectional study to determine the prevalence of anti-DENV immunoglobulin G (IgG) antibodies in expatriate and local persons affiliated with an American veterinary school there. Methodology: This campus community comprised mostly expatriate students and faculty and Kittitian administrative staff. In 2009, a stratified random sample of students, faculty and staff was invited to complete an electronic survey to assess risk factors for DENV and provide blood for testing for anti-DENV IgG antibodies by an enzyme-linked immunosorbent assay. IgG-positive specimens were also tested by a 90% plaque reduction neutralization test (PRNT90) to determine immunoreactivity to DENV (1-4) serotypes and West Nile virus. Risk factors for anti-DENV IgG seropositivity were determined using simple and adjusted logistic regression. Results: Of the 118 participants, the overall prevalence of DENV IgG antibodies was 44.1% (95% confidence interval [CI]: 35.1-53.0%), ranging from 30.1% in students, 100.0% in staff and 57.9% in faculty (p < 0.001). Duration of residence in St. Kitts was the only variable significantly associated with seropositivity on multiple logistic regression (adjusted odds ratio [95% CI]: 1.21 [1.07-1.37]). The serotype of DENV was determined in 11 persons: DENV-1 (n = 4), DENV-2 (n = 3), and DENV-3 (n = 4). Conclusions: Expatriate students and faculty moving to St. Kitts from non-endemic areas were at high risk of DENV infection. There is a need for increased emphasis on pre-travel mosquito-borne virus prevention education for persons moving to St. Kitts to study and work.


2020 ◽  
Vol 114 (4) ◽  
pp. 255-263 ◽  
Author(s):  
Punam Mangtani ◽  
Isha Berry ◽  
Wendy Beauvais ◽  
Hannah R Holt ◽  
Amit Kulashri ◽  
...  

Abstract Background Brucellosis is an important neglected zoonosis. Effective cattle vaccines are available but are infrequently used in India, where rural households commonly own one or two cattle as sources of protein and income. We assessed the prevalence of infection and risk factors in humans. Methods We conducted a cross-sectional sero-survey in randomly selected individuals in 60 villages in Punjab. Infection prevalence was assessed by positive Rose Bengal testing or immunoglobulin G enzyme-linked immunosorbent assay. Risk factors were adjusted for potential confounding using multivariable analyses. Results Of the 1927 subjects who were approached, 93% agreed to participate. Age-standardised prevalence for Brucella infection was 2.24% (95% confidence interval [CI] 1.61 to 3.11). More than 60% of households kept cattle and 10% assisted with calving or abortions. Nearly all individuals consumed boiled cow/buffalo milk from their own or neighbours' cattle and 3.3% consumed goat’s milk. There was a 2.18 times increased odds (95% CI 0.96 to 4.95) of infection with calving/abortions and a 4.26 times increased odds (95% CI 1.33 to 13.6) with goat’s milk but not bovine milk consumption. Conclusions An association with calving/abortions and goat’s milk consumption was seen. Brucella vaccination of household livestock would reduce the risk to humans in such settings. Additional measures include biosecurity training around calving/abortions, education to boil all milk and for healthcare workers to test for brucellosis.


2021 ◽  
Vol 1 (2) ◽  
Author(s):  
Leonard Fonkeng Sama ◽  
Michel Noubom ◽  
Romeo Joël Nguekam ◽  
Solange Dabou ◽  
Thibau Flaurant Tchouangueu ◽  
...  

Background:Chlamydia trachomatis (CT) infection in the genitourinary tract is the most prevalent bacterial sexually transmitted disease (STD) worldwide. Genital chlamydial infection has a huge impact on sexual and reproductive health, and it is very common in developed and developing countries. This study aimed to determine the seroprevalance and risk factors for C. trachomatisinfection in women seeking medical care in the locality of Mbouo-BanjounWest Region of Cameroon. Methods: We conducted a cross-sectional hospital based study from November 2016 to June 2017 in which we recruited 204 consenting women aged 18 to 55 years. A questionnaire was administered to study participants and potential risk factors for Chlamydia exposure sought. Venous blood was collected and serum from each participant analysed for C. trachomatis infection as evidenced by positive anti-C. trachomatisIgG and IgM antibodies detected using the Sandwich Enzyme-Linked ImmunoSorbent Assay (ELISA) technique. The proportion of anti-C. trachomatis antibody was calculated and predictors of C. trachomatis infection analysed by univariate and multivariate regression. Epi-Info 7 was used for statistical analyses. A p < 0.05 was considered significant in all analyses. Results: The seroprevalence of anti-C. trachomatisantibodies (IgM or IgG) was found to be62.25% [127/204]. Among seropositive women, 37.15% [77/204] were seropositive for IgG antibodies while 47.54% [97/204] were seropositive for IgM antibodies and 23.04% [47/204] where seropositive for both IgM and IgG antibodies. Among the risk factors evaluated, marital status (P= 0.03) and knowledge of Chlamydia (P= 0.001) were observed to be an independent risk factor of C. trachomatisinfection. Conclusions: Our findings suggest recent C. trachomatisexposure is high in our study population, and may constitute a significant risk factor for, ocular and pulmonary infection in new born child, infertility to women. Education and screening of HIV-positive individuals and pregnant women for C. trachomatisinfection may be important primary prevention strategies in this population.


2019 ◽  
Vol 6 (3) ◽  
pp. 63 ◽  
Author(s):  
Abdallah ◽  
Kamel ◽  
Karima ◽  
Samir ◽  
Djamel ◽  
...  

A cross-sectional study aimed at assessing the seroprevalence and identifying the risk factors for Toxoplasma gondii infection in cattle, sheep, and goats in eight provinces located in two main Algerian agro-ecological zones was carried out from October 2015 to March 2018. Blood sera from 4074 animals of both sexes were tested for the presence of anti-T. gondii IgG antibodies, using the indirect, enzyme-linked, immunosorbent assay technique (ELISA). Moreover, to identify the potential risk factors of T. gondii infection, a survey through a breeders’ questionnaires was conducted. Nearly one-fourth of the total number of animals tested (1024/4074)—i.e., 25.1%--were seropositive. The seroprevalence in cattle, sheep, and goats was 28.7%, 25.6%, and 11.9%, respectively. The area, sex, age, and herd size were identified as risk factors for T. gondii infection. Higher seropositivity rates were recorded in cows and goats (odds ratio (OR) = 1.63 and 6.4), in old animals (cattle, OR = 2.1; sheep, OR = 1.9; and goat, OR = 3.9), and in small size herds (cattle, OR = 2.5; sheep, OR = 1.9; goat, OR = 2.2). In conclusion, there is widespread T. gondii infection in cattle, sheep, and goats in these two strategic agricultural areas. The identification of the risk factors determines the type of measures and strategies to be undertaken to reduce, control, and prevent T. gondii infection in domestic animals, and thereby reduce human infection.


2016 ◽  
Vol 8 (3) ◽  
pp. 301-305
Author(s):  
Chukwunonso Francis OBI

A cross-sectional survey utilizing semi-structured questionnaires was used to study the herdsmen and livestock farmers’ perception, attitudes and risk factors towards zoonotic diseases in Awka North and South Local Government Area. Data obtained were analyzed using chi-square on SPSS (Version 15.0) at a significance level of p < 0.05 to determine possible associations between variables and perceptions of zoonotic diseases. Out of the 384 respondents, 214 (55.7%) had heard about zoonotic diseases. Avian influenza (95.3%), rabies (90.9%) and bovine tuberculosis (64.3%) were perceived by the respondents to be zoonotic. Viruses (82.3%), punishment from gods (72.4%) and bacteria (52.1%) were also perceived by the respondents as major causes of zoonotic diseases, whereas 62% were of the view that zoonotic diseases are of no consequence. Only 26.3% (101) had overall knowledge of zoonotic diseases. Slaughtering of sick animals, drinking of raw milk, skin to skin contact with animals, contact with animals’ placenta, handling of animal with open wounds/cuts and keeping of pets were indicted as attitudes and risk factors of zoonotic diseases amongst the respondents. Significant associations (p < 0.05) were found between perceptions/awareness of zoonotic diseases and age, educational status and location. In conclusion, the herdsmen and livestock farmers’ awareness/perception of zoonotic diseases is abysmally poor in the study area, thus public education on zoonotic diseases is therefore hugely recommended.


2018 ◽  
Vol 8 (1) ◽  
pp. 01-07
Author(s):  
Alfred Eboh

Background: The hawking of wares by children has been a serious issue confronting the Nigerian society. Children hawk in some of the most horrible conditions conceivable, where they face a serious risk of injury, chronic illness, kidnapping, rape or death. Objective: The focus of this study was to assess the perceived effects of street hawking on the well-being of children in Anyigba, Dekina Local Government Area of Kogi State. Methods: The population of this study consists of parents of the street hawkers in Anyigba while cross-sectional survey design was used through the purposive sampling technique to choose the sample size of one hundred and sixty-two (162) respondents. The validated structured questionnaire and In-Depth Interviews (IDIs) served as the instruments for the data collection respectively. The hypotheses were tested using Chi-Square at a predetermined 0.05 level of significance. The quantitative data were analysed with the aid of the SPSS (version 20). Results: The results indicated among others that street hawking had significant social implications and physical consequences on children's moral behaviour as well as health status in the study area. Conclusion: The study, therefore, concluded that the government of Kogi State should carry out an enlightenment campaign through the media and religious institutions on the negative consequences of street hawking are recommended as panacea. Also, the child right act instrument and its implementation should be strengthened in order to curb street hawking in the study area.


2019 ◽  
Vol 15 (1) ◽  
pp. 10-16
Author(s):  
Shreyan Kar ◽  
Tushar Kanti Das ◽  
Prasanta Kumar Mohapatra ◽  
Brajaballav Kar ◽  
Anupama Senapati ◽  
...  

Background: While it is apparent that old age is associated with multiple health concerns, the extent of its multiplicity and burden is often not clear. It was intended to find out self-reported health concerns for one month and cardiovascular risk factors in middle and older adults. Methods: In the cross-sectional survey, attendees of a Healthy Ageing Conference were approached with a semi-structured questionnaire about their health concerns and cardiovascular risks. Risk of a cardiovascular event in 10 years based on QRISK3 was calculated. Results: A considerable proportion of older adults had a range of physical symptoms, depressive mood state and memory problems. Mean number of health problems reported were 4.8±3.3 (male 4.4±3.1 and female 5.0±4.3). Cardiovascular risk was high, mean QRISK3 score for males were 22.2% (±14.4), and for females 10.3% (±6.6) (p<0.05). On average, the heart age was increased by 7.9±6.2 years (8.6±6.6 years for males and 5.0±3.3 for females). The relative risk of participants was 2.1 for males and 1.5 for females for heart attack or stroke within the ten years, compared to healthy persons. The symptoms and risk factors were elicited easily, and the process probably facilitated improving the awareness about the health concerns holistically. The survey also identified issues related to the engagement of older adults in the existing health care systems. Conclusions: The results suggested that questionnaire-based health screening in a community can identify a range of health concerns and identify multi-morbidity in general and cardiovascular risks in particular. This process may help to focus on the appropriate public health awareness and intervention programmes required in the community.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Beibei Feng ◽  
Kedi Chen ◽  
Xiaoxia Zhu ◽  
Wing-Yuk Ip ◽  
Lars L. Andersen ◽  
...  

Abstract Background Carpal tunnel syndrome (CTS) is a common cause of pain, numbness and tingling in the wrist and hand region and is associated with repetitive wrist and hand use in office workers. However, scarce knowledge exists about the epidemiology of clinically confirmed CTS among Chinese office workers. This study aimed to investigate the prevalence of wrist/hand symptoms and CTS in office workers in China and to identify associated risk factors. Methods A cross-sectional survey was carried out in a metropolitan city in China involving 969 respondents (aged 17–49 years) from 30 workplaces. A questionnaire was distributed to each participant to collect their demographic, work-related physical and psychosocial factors, and wrist and hand symptoms. The wrist and hand pain/numbness symptoms were marked on a body chart and the nature and intensity of symptoms, nocturnal symptoms, as well as aggravating activities were also recorded. Clinically confirmed CTS cases were screened based on the history, Phalen’s test, Tinel Sign and skin sensation testing among symptomatic respondents. Logistic regression was employed to estimate the odds ratio (OR) and 95% confidence interval (95% CI) for the occurrence of self-reported wrist and hand symptoms and clinically confirmed CTS. Results The clinically confirmed CTS prevalence was 9.6%. The prevalence of wrist and hand symptoms were 22 and 15%, respectively. Frequently working in pain was associated with higher odds of CTS. Multivariate modelling adjusted for age and gender showed that prolonged computer use time and working without breaks were associated with presence of wrist/hand symptoms (adjusted ORs: 1.11 (95% CI 1.02–1.22) and 1.88 (95% CI 1.12–3.14)). Educational level was inversely associated with CTS and smoking was associated with wrist/hand complaints (adjusted OR: 2.20 (95% CI 1.19–4.07)). Conclusions The prevalence of work-related clinically confirmed CTS symptoms among young office workers in China is high. Frequently working in pain is closely associated with clinically confirmed CTS. Intense computer use and no breaks at work are associated with wrist and hand symptoms.


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