scholarly journals An Investigation of the Prevalence of Subclinical Brain Lesions in MRI Images of Migraine Patients

2018 ◽  
Vol 6 (7) ◽  
pp. 1239-1243 ◽  
Author(s):  
Khadijeh Haji Naghi Tehrani

BACKGROUND: The use of the MRI method has opened up a new perspective on pathogenesis, diagnosis and treatment of brain lesions.AIM: Therefore, this study aimed to evaluate the prevalence of brain subclinical lesions in MRI images of migraine patients.METHODS: This cross-sectional study was conducted on 300 patients with a migraine referred to Baqiyatallah and Amir Al-Momenin Hospitals from 2005 to 2006. We measured the relationship between the results of MRI and the type of brain subclinical lesion by indices such as age, gender, type of a migraine, the number of migraine attacks, blood pressure and heart diseases, cholesterol, diabetes and thyroid diseases. Finally, data were analysed by IBM SPSS statistics software version 23. The significance level in this study was considered as P > 0.05.RESULTS: From among 300 patients, 87.7% were women in the age range of 13-72 years. Moreover, the results indicated that with increasing age, blood pressure and some migraine attacks, the frequency of abnormal MRI also is increased significantly as well as the ratio of a migraine with aura was significantly higher than a migraine without aura in individuals with abnormal MRI. Also, the ratio of white matter lesions (WML) is higher in a classical migraine (a Migraine with aura). Statistical analyses did not reveal any significant relationship between MRI results on age, diabetes, cholesterol, heart and thyroid diseases.CONCLUSION: The prevalence of abnormal MRI in older people and those with high blood pressure and migraine with aura is higher, and the ratio of subclinical lesions in the population of a migraine with aura is more common than a migraine without aura.

Cephalalgia ◽  
2019 ◽  
Vol 40 (4) ◽  
pp. 347-356 ◽  
Author(s):  
Claudia Pisanu ◽  
Emma Lundin ◽  
Martin Preisig ◽  
Mehdi Gholam-Rezaee ◽  
Enrique Castelao ◽  
...  

Objective Migraine and major depressive disorder show a high rate of comorbidity, but little is known about the associations between the subtypes of major depressive disorder and migraine. In this cross-sectional study we aimed at investigating a) the lifetime associations between the atypical, melancholic, combined and unspecified subtype of major depressive disorder and migraine with and without aura and b) the associations between major depressive disorder and its subtypes and the severity of migraine. Methods A total of 446 subjects with migraine (migraine without aura: n = 294; migraine with aura: n = 152) and 2511 controls from the population-based CoLaus/PsyCoLaus study, Switzerland, were included. Associations between major depressive disorder subtypes and migraine characteristics were tested using binary logistic or linear regression. Results Melancholic, combined and unspecified major depressive disorder were associated with increased frequency of migraine with aura, whereas only melancholic major depressive disorder was associated with increased frequency of migraine without aura. Lifetime and unspecified major depressive disorder were associated with severe migraine intensity among subjects with migraine with aura but not migraine without aura, while combined major depressive disorder was associated with higher migraine frequency independently from migraine subtype. Conclusion This study suggests that melancholic but not atypical major depressive disorder is associated with migraine and migraine subtypes. Future studies exploring pathophysiological mechanisms shared between melancholic depression and migraine are warranted.


Cephalalgia ◽  
2018 ◽  
Vol 39 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Gabriela F Carvalho ◽  
Flávia Heck Vianna-Bell ◽  
Lidiane L Florencio ◽  
Carina F Pinheiro ◽  
Fabiola Dach ◽  
...  

Objective To assess the presence and handicap due to vestibular symptoms in three subgroups of patients with migraine and controls. Methods Women between 18–55 years old were diagnosed by headache specialists and stratified as migraine with aura (n = 60), migraine without aura (n = 60), chronic migraine (n = 60) and controls (n = 60). Information regarding demographics, headache and vestibular symptoms were collected in this cross-sectional study. The self-perceived handicap related to vestibular symptoms was assessed through the Dizziness Handicap Inventory questionnaire. Results A total of 85% of women with migraine with aura and chronic migraine had vestibular symptoms contrasted to 70% of the migraine without aura group ( p < 0.05), and 12% of the control group reported symptoms ( p < 0.0001). Patients with migraine exhibited greater Dizziness Handicap Inventory scores than controls ( p < 0.001); and migraine with aura and chronic migraine groups reached greater scores than migraine without aura ( p < 0.01). Presence of migraine is associated with a greater risk of vestibular symptoms (migraine without aura: 5.20, migraine with aura: 6.60, chronic migraine:6.20, p < 0.0003) and with a greater risk of moderate-to-severe handicap (migraine without aura: 20.0, migraine with aura: 40.0, chronic migraine: 40.0, p < 0.0003). The presence of aura and greater migraine frequency adds to the risk of any handicap (migraine with aura: 1.9, chronic migraine: 1.7, p < 0.04) and to the risk of moderate-to-severe handicap (migraine with aura: 2.0, chronic migraine: 2.0, p < 0.0003). Migraine aura, intensity and frequency predict 36% of the dizziness handicap. Conclusion The prevalence of vestibular symptoms is increased in migraine during and between headache attacks, particularly in migraine with aura and chronic migraine along with an increased handicap due to those symptoms. Vestibular symptoms among subgroups of migraine should be considered when evaluating the functional impact of migraine.


Cephalalgia ◽  
1992 ◽  
Vol 12 (4) ◽  
pp. 221-228 ◽  
Author(s):  
Birthe Krogh Rasmussen ◽  
Jes Olesen

In a cross-sectional study of headache disorders in a representative general population of 1,000 persons the epidemiology of migraine with aura (MA) and migraine without aura (MO) was analysed in relation to sex and age distribution, symptomatology and precipitants. The headache disorders were classified on the basis of a clinical interview as well as a physical and a neurological examination using the operational diagnostic criteria of the International Headache Society (IHS). Lifetime prevalence of MA was 5%, male:female ratio 1:2. Lifetime prevalence of MO was 8%, M:F ratio 1:7. Women, but not men, were significantly more likely to have MO than MA. Neither MA nor MO showed correlation to age in the studied age interval (25–64 years). Premonitory symptoms occurred in 16% of subjects with MA and in 12% with MO. One or more precipitating factor was present in 61% with MA and in 90% with MO. In both MA and MO the most conspicuous precipitating factor was stress and mental tension. Visual disturbances were the most common aura phenomenon occurring in 90% of subjects with MA. Aura symptoms of sensory, motor or speech disturbances rarely occurred without coexisting visual disturbances. The pain phase of MA fulfilled the criteria for MO of the IHS. Headache was, however, less severe and shorter lasting in MA than in MO. Onset at menarche, menstrual precipitation, menstrual problems, influence of pregnancy and use of oral contraceptives all showed some relationship with the presence of MO and less with MA. The present findings suggest that MA and MO share the pain phase. Among subjects with MA and MO, 50% and 62%, respectively, had consulted their general practitioner because of migraine. Selection bias in previous clinical studies is demonstrated by comparisons with the present unselected sample.


2011 ◽  
Vol 69 (4) ◽  
pp. 613-619 ◽  
Author(s):  
Waldmiro Antônio Diégues Serva ◽  
Vilneide Maria Santos Braga Diégues Serva ◽  
Maria de Fátima Costa Caminha ◽  
José Natal Figueiroa ◽  
Emídio Cavalcanti Albuquerque ◽  
...  

OBJECTIVE: To describe the course of migraine without aura and migraine with aura during pregnancy and factors that could influence its course, among migraine sufferers before pregnancy. METHOD: A cross sectional study undertaken at the IMIP, Brazil. Out of 686 consecutively assisted women, at the first postnatal week, 266 were identified as migraine sufferers before pregnancy. RESULTS: There was migraine remission in 35.4%, 76.8% and 79.3% among migraine without aura sufferers and 20.7%, 58.6% and 65.5% among those with migraine with aura, respectively in the first, second and third trimesters. Statistically significant difference was found when the first trimester was compared with the second and third trimesters. The factors associated with the presence of migraine during pregnancy were: multiparity, menstrually related migraine without aura prior to pregnancy and illness during pregnancy. CONCLUSION: The study contributed to elucidate the course of migraine during pregnancy in migraine sufferers prior to pregnancy.


Rev Rene ◽  
2015 ◽  
Vol 16 (5) ◽  
pp. 722 ◽  
Author(s):  
Paula Cristina Araújo Morais ◽  
Rafaella Pessoa Moreira ◽  
Paula Alves de Lima ◽  
Maria das Graças Fernandes Silva ◽  
Jerry Deyvid Freires Ferreira ◽  
...  

Objectives: to investigate the blood pressure values; to identify the history of cardiovascular diseases and lifestyles of elderly at a social assistance reference center. Methods: cross-sectional study, conducted with fifty elderly. A form with questions regarding social data, history of diseases and lifestyles was applied. In sequence, the blood pressure was checked. Results: it was observed that 73.3% of the elderly had pressure alterations. Systolic alterations were identified in 73.3%, and diastolic, in 10% of the elderly. The most frequently referred cardiovascular diseases were hypertension (70%), diabetes mellitus(38%) and dyslipidemia (32%). The most common risk factors were current or past use of tobacco whether active (68%) or passive (26%), and physical inactivity (48%). Conclusion: people with altered blood pressure and associated risk factors were identified. This situation may contribute to directing nursing care and addressing the real needs of elderly population. 


Author(s):  
Giovana Zarpellon Mazo ◽  
Janeisa Franck Virtuoso ◽  
Rodrigo De Rosso Krug ◽  
Enaiane Cristina Menezes ◽  
Marize Amorim Lopes

The aim of this study was to associate sitting time with major diseases affecting octogenarians. This observational cross-sectional study involved 351 octogenarians, being 323 women and 28 men, with a mean age of 84.1 (SD = 3.9). Sociodemographic data, health conditions and responses to Section 5 of the International Physical Activity Questionnaire (IPAQ) were entered into a diagnostic program in order to determine the weekly time spent sitting down. Descriptive (single frequency, percentage, mean, and standard deviation) and inferential statistics (Mann-Whitney U test and binary logistic regression) were used. The data were examined at a 5% significance level. The most frequent diseases in the octogenarians were high blood pressure (60.1%), heart diseases (26.5%), diabetes (21.9%), dyslipidemia (21.7%), osteoporosis (18.5%), and osteoarthritis (14.5%). The longer they spent sitting down, the greater the risk of developing diabetes (OR = 4.5, 95% CI 2.5 to 8.2) and dyslipidemia (OR = 2.9, 95% CI 1.6 to 5.0). A sitting time of more than 1,710 minutes per week can predict the occurrence of diabetes (p = 0.002), while sitting for more than 1,380 minutes per week can predict the occurrence of dyslipidemia (p = 0.002). Sitting time was found to be a risk factor for the occurrence of diabetes and dyslipidemia in the studied octogenarians. Chronic diseases were associated with sedentary behavior.


2008 ◽  
Vol 19 (4) ◽  
pp. 313-317 ◽  
Author(s):  
Augusto César Braz Hollanda ◽  
Ana Helena Gonçalves de Alencar ◽  
Cyntia Rodrigues de Araújo Estrela ◽  
Mike Reis Bueno ◽  
Carlos Estrela

This cross-sectional study examined the prevalence of endodontically treated teeth in 1,401 Brazilian adults. Panoramic radiographs were selected at the Radiological Center of Orofacial Images (CRIOF, Cuiabá, MT, Brazil) between August 2002 and September 2007. Three independent endodontists discussed interpretation criteria and classified specimens according to the following data: presence of root canal treatment, which was defined as partially or completely filled canal space, regardless of whether filling ended at the radiographic apex or not; presence of intracanal post; and associated apical periodontitis. Odds ratio, logistic regression and a chi-square test were used for statistical analyses. Significance level was set at p<0.05. Of 29,467 teeth evaluated, 6,313 (21.4%) were treated endodontically. Endodontic treatment was most frequent in maxillary premolars and molars, whereas mandibular incisors showed the lowest prevalence. Most endodontically treated teeth were found in people aged 46 to 60 years (47.6%, p<0.001) and the prevalence increased with age in this age range. Females (61.9%, p<0.001) showed a higher prevalence of teeth with root fillings than males. The present study found a higher prevalence of endodontically treated teeth in a Brazilian adult population compared to the prevalence reported in epidemiological studies conducted in other countries.


2020 ◽  
Vol 7 (2) ◽  
pp. 256-263
Author(s):  
Abdul Qodir

Penatalaksanaan farmakologis dan non farmakologis dipercaya dapat mengontrol tekanan darah dan mencegah komplikasi, tetapi banyak pasien hipertensi tekanan darahnya tidak terkontrol. Hal tersebut dikarenakan kepatuhan yang buruk dalam melaksanakan rekomendasi gaya hidup. Penelitian ini bertujuan untuk menganalisis determinan faktor yang berhungan dengan kepatuhan melaksanakan rekomendasi modifikasi gaya hidup. Penelitian ini menggunakan metode cross-sectional di pukesmas dinoyo Kota Malang tahun 2019. Teknik pengambilan sampel menggunakan Consecutive Sampling. Kuesioner yang digunakan meliputi : karakteristik demografi, pengetahuan dan rekomendasi mofifikasi gaya hidup pasien hipertensi. Hubungan antara rekomendasi modifikasi gaya hidup dengan variabel independen dianalisis menggunakan uji chi square dan analisis regresi logistik. 140 pasien hipertensi berpartisipasi dalam penelitian ini (60 laki-laki, 80 wanita). Prevalensi kepatuhan adalah 28,6 %. Tingkat pengetahuan berhubungan signifikan  dengan kepatuhan melaksanakan rekomendasi gaya hidup (p=0,00). Jenis kelamin, usia, dan tingkat pendidikan tidak mempunyai hubungan signifikan dengan kepatuhan rekomendasi modifikasi gaya hidup (p= 0,06; p=0,21; p=0,87). Pengetahuan mempunyai hubungan yang signifikan dengan kepatuhan rekomendasi modifikasi gaya hidup. Management of pharmacological and non-pharmacological is believed to control blood pressure and prevent complications,  but many hypertensive patients have uncontrolled blood pressure. This is due to poor adherence to recommended lifestyle modifications. This study was aimed to determine the factors associated with adherence to recommended lifestyle modifications of hypertensive patients. A cross-sectional study was conducted in Pukesmas Dinoyo Malang in 2019. Consecutive Sampling was used to select study subjects. The questionnaire included information about demographic characteristics, knowledge, practice of lifestyle-modification measures. Associations between adherence to lifestyle modification and independent variables were analyzed using chi square and multivariate logistic regression analysis. 140 hypertensive patients participated in the study (60 men, 80 women). The prevalence of adherence was 28.6%. The level of knowledge was significant associated with adherence to recommended lifestyle modifications (p = 0.00). Genders , age, and educational level were no significant associated with to recommended lifestyle modifications (p= 0.06; p=0.21; p=0.87). Knowledge was significant associated with adherence to recommended lifestyle modifications of hypertensive patients.


Sign in / Sign up

Export Citation Format

Share Document