scholarly journals The Correlation between Hemoglobin Concentration during Pregnancy with the Maternal and Neonatal Outcome

2019 ◽  
Vol 7 (4) ◽  
pp. 594-598
Author(s):  
Sarma Nursani Lumbanraja ◽  
Muhammad Rizki Yaznil ◽  
Dewi Indah Sari Siregar ◽  
Adriani Sakina
Keyword(s):  
Pregnant Women ◽  
Neonatal Outcome ◽  
Post Partum ◽  
Haemoglobin Concentration ◽  
Hemoglobin Concentration ◽  
Third Trimester ◽  
Hospital Outpatient Clinic ◽  
The World ◽  
Anemia During Pregnancy ◽  
Post Partum Haemorrhage

BACKGROUND: The prevalence of anaemia is higher among women, including pregnant women. The estimation was about 24.8% of the population in the world suffering anaemia. Anaemia during pregnancy is a big problem because it can contribute morbidity and mortality, either in mother or newborn. The impacts of anaemia during pregnancy included post-partum haemorrhage, low birth weight (LBW), preterm delivery, and low Appearance, Pulse, Grimace, Activity, Respiration (APGAR) score. AIM: This study aimed to determine the correlation between haemoglobin concentration during pregnancy and the outcome of mothers and newborns. METHODS: It was a cohort study that included 200 pregnant women in second or third trimester at antenatal care of Sundari General Hospital Outpatient Clinic on February until September 2018. The participants were interviewed using a questionnaire, and their blood was checked to measure haemoglobin concentration using portable Easy Touch Hemoglobinometer. In the next three until six months, the following investigation was conducted to assess the maternal and neonatal outcome. RESULTS: The result of this study showed among the maternal outcome, only antepartum haemoglobin concentration had a statistically significant correlation with the haemoglobin concentration during pregnancy (p < 0.05), meanwhile, among the neonatal outcome. LBW was the only factor that statistically significantly correlated to the haemoglobin concentration during pregnancy (p < 0.05). CONCLUSION: We can conclude that once anaemia occurs in pregnant women, then the women kept suffering from anaemia with its correlation was statistically significant. Keywords : hemoglobin concentration, anemia during pregnancy, maternal, neonatal outcome

scholarly journals Serum Glucose Level and Hemoglobin Concentration in Third Trimester of Pregnancy

2016 ◽  
Vol 10 (2) ◽  
pp. 67-70
Author(s):  
Sumaira Sufrin ◽  
Akhtarun Nessa ◽  
Md Tazul Islam
Keyword(s):  
Gestational Diabetes ◽  
Pregnant Women ◽  
Glucose Level ◽  
Hemoglobin Concentration ◽  
Serum Glucose ◽  
Serum Glucose Level ◽  
Control Group ◽  
Third Trimester ◽  
Cross Sectional ◽  
Altered Glucose

Background : Pregnancy is a state of physiological adaptations to accommodate the needs of the developing fetus. Elevated blood glucose during pregnancy could lead to gestational diabetes and anemia could cause intercurrent infection.Objective: To assess the serum glucose level & hemoglobin concentration in third trimester of pregnancy in order to find out the risk of gestational diabetes and physiological anemia.Method: This cross-sectional study was carried out in the Department of Physiology Mymensingh Medical College, Mymensingh, between the period of July, 2013 to June,2014. One hundred pregnant women in their third trimester of pregnancy aged 18-35years were enrolled in study group and age matched 100 healthy non-pregnant women were control group. Random serum glucose was estimated by GOD-PAP method and hemoglobin concentration was measured by cyanmethemoglobin (CMG) method. Data were analyzed by student’s un paired t test and chi square test.Result: Mean serum glucose level (6.76±1.72 mmol/L) was significantly higher and hemoglobin concentration (8.21±1.23 g/dl) was significantly lower in pregnant women than non-pregnant women. Increased frequency of high glucose (38%) and low H b(88%) was found in pregnant women in third trimester.Conclusion: This study concludes altered glucose metabolism may lead to gestational diabetes as well as physiological anemia may be exaggerated in third trimester of pregnancyBangladesh Soc Physiol. 2015, December; 10(2): 67-70

scholarly journals Correlation study between increased fetal movement during the third trimester and neonatal outcome

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Cuiqin Huang ◽  
Wei Han ◽  
Yajing Fan
Keyword(s):  
Amniotic Fluid ◽  
Pregnant Women ◽  
Gestational Age ◽  
Neonatal Outcome ◽  
Stress Test ◽  
Neonatal Outcomes ◽  
Control Group ◽  
Third Trimester ◽  
The Third ◽  
Fetal Movements

Abstract Background We aimed to analyze the correlation between increased fetal movements in the third trimester and neonatal outcomes. Methods We enrolled pregnant women (n = 219) who reported increased/excessive fetal movements in the third trimester in our hospital. A control group of healthy women (n = 278) who had undergone regular childbirth and delivery in our hospital during the same period and did not report abnormal fetal movements were also recruited. All pregnant women underwent fetal non-stress test. We analyzed the neonatal weight, appearance, pulse, grimace, activity, and respiration score, degrees of amniotic fluid contamination, amniotic fluid volume, conditions of umbilical cord around the neck and cord length, and incidence of small for gestational age. In addition, the incidence of preterm delivery, cesarean section rate, postpartum hemorrhage, and other postpartum complications were also analyzed. We then analyzed the correlation between increased/excessive fetal activity and neonatal outcomes. Results Women with complaints of increased/excessive fetal movements exhibited increased fetal movements mainly around 31 and 39 weeks of gestation. Several pregnancy variables, including number of previous delivery, gestational age (less than 34 weeks and more than 37 weeks) and vaginal birth rate, were associated with increased/excessive fetal movements. In addition, women who reported increased/excessive fetal movements had higher odds of large for gestational age (LGA), particularly those with gestational age over 37 weeks. Conclusion Increased/excessive fetal movements may be used to predict adverse neonatal outcome such as LGA.

scholarly journals Maternal and perinatal outcomes in diabetic pregnancies at BPKIHS

2017 ◽  
Vol 6 (6) ◽  
pp. 2262
Author(s):  
Anamika Das
Keyword(s):  
Diabetes Mellitus ◽  
Pregnant Women ◽  
Neonatal Outcome ◽  
Post Partum ◽  
Perinatal Outcomes ◽  
Perinatal Complications ◽  
Overt Diabetes ◽  
Global Pandemic ◽  
The Government ◽  
Sedentary Life Style

Background: Diabetes has become a global pandemic because of aging population, sedentary life style, urbanization, and increasing incidence of obesity; this study was aimed to identify the maternal and perinatal outcome in Diabetes complicating pregnancies and to compare the outcome in Gestational Diabetes Mellitus and Overt Diabetes Mellitus.Methods: This was a descriptive study conducted from 1st April 2013-31st March 2014 on total 75 pregnant women. All antenatally diagnosed cases of GDM and overt diabetes, booked or unbooked, whoever came for delivery were studied. Both mothers and neonates were followed up in ante-partum, intra-partum, and post-partum period till their stay in hospital. Management of the patient was done as per the hospital protocol.Results: Out of 75 cases enrolled, 25.33% had GDM and 16% had overt diabetes mellitus.57.33%patients were multigravida, among which 40% had GDM and 17.33% had Overt Diabetes Mellitus.61.33% patients underwent LSCS, of which 41.33% had GDM and 20% had overt diabetes mellitus. Obstetric complication was more common in GDM patients (30.66%) compared to Overt (22.66%). 89.33%babies had good neonatal outcome and 10.66% babies (6.66% of GDM mothers and 4% of overt mothers) had poor neonatal outcome (macrosomia, hypoglycaemia, prematurity, respiratory distress with NICU stay and use of antibiotics, poor APGAR (<7 at 5 min), gross congenital malformation, hyperbilirubinemia, stillbirth and neonatal death).Conclusions: Maternal and perinatal complications was commonly seen in diabetic pregnancy though more common in GDM.The time has come for the Government of Nepal to implement an effective plan to the benefit of pregnant women with diabetes during pregnancy.

Superficial Hand Vein Responses to NG-Monomethyl-l-Arginine in Post-Partum and Non-Pregnant Women

1996 ◽  
Vol 90 (6) ◽  
pp. 493-497 ◽  
Author(s):  
G. A. Ford ◽  
S. C. Robson ◽  
Z. A. Mahdy
Keyword(s):  
Nitric Oxide ◽  
Pregnant Women ◽  
Post Partum ◽  
Normal Pregnancy ◽  
Third Trimester ◽  
Hand Vein ◽  
Vascular Beds ◽  
Oxide Synthase ◽  
Constrictor Response ◽  
Venous Vasculature

1. During human pregnancy marked vasodilatation occurs in arterial and venous vascular beds. The mechanisms responsible for this change remain unclear. The contribution of increased nitric oxide activity to vasodilatation associated with pregnancy was determined by examining superficial hand vein responses to NG-monomethyl-l-arginine, an inhibitor of nitric oxide synthase, in post-partum women 24–48 h after delivery when vasodilatation remains at levels present during the third trimester. 2. Seventeen healthy women, 24–48 h post partum, and 13 healthy non-pregnant women were studied. Eight of the post-partum women underwent repeat studies 12–16 weeks after delivery. 3. NG-monomethyl-l-arginine (100 nmol/min) resulted in venoconstriction in non-constricted veins (baseline, 0%; 5 min, 26 ± 9%; 10 min, 14 ± 8%; 15 min, 8 ± 7%; means ± SEM) and noradrenaline-constricted veins (5 min, 30 ± 7%; 10 min, 24 ± 10%; 15 min, 14 ± 11%). No constrictor response to NG-monomethyl-l-arginine was present in the same women 12 weeks post partum (5 min, 1 ± 4%; 10 min, 0 ± 3%; 15 min, 1 ± 4%) or in the non-pregnant control subjects in non-constricted (5 min, 2 ± 3%; 10 min, 4 ± 3%; 15 min, 2 ± 2%) or noradrenaline-constricted veins (Smin, − 2 ± 7%; 10 min, 1 ± 9%; 15 min, − 5 ± 7%). 4. These findings indicate that nitric oxide activity is increased in the immediate post-partum period in venous vasculature, and support the hypothesis that increased nitric oxide activity may be responsible for the vasodilatation observed during normal pregnancy.

scholarly journals HUBUNGAN KETERATURAN KUNJUNGAN ANC (ANTENATAL CARE) DAN KEPATUHAN KONSUMSI TABLET FE DENGAN KEJADIAN ANEMIA PADA IBU HAMIL TRIMESTER III DI KECAMATAN MARON PROBOLINGGO

2019 ◽  
Vol 3 (1) ◽  
pp. 46
Author(s):  
Veny Nurmasari ◽  
Sri Sumarmi
Keyword(s):  
Antenatal Care ◽  
Pregnant Women ◽  
Random Sampling ◽  
Sampling Method ◽  
Case Control Study ◽  
Simple Random Sampling ◽  
Third Trimester ◽  
Anemia During Pregnancy ◽  
The Government ◽  
Control Study

Background: Anemia during pregnancy as a risk factor for maternal and fetal health. The government has implemented iron tablet distribution for pregnant women to prevent anemia during pregnancy. Problems arasie due to non-compliance of pregnant women in consuming iron tablets.Objectives: The purpose of the study was to analyze the correlation between regularity of antenatal care visits (ANC), and comlpliance of iron tablets consumption with anemia in third trimester pregnant women.Method: The study used a case control study design. The samples were 30 consists of 15 cases and 15 control taken by simple random sampling method. This study correlated the regularity of ANC visits and compliance to consumption of iron tablets between regularity of antenatal care visits (ANC), and comlpliance of iron tablets consumption with anemia in third trimester pregnant women.The study was conducted in the working area of Maron Health Center Probolinggo in May – August 2018. Data were analyzed using chi square.Results: The results showed that the regularity of antenatal care visits (ANC) (p = 0.001; OR = 4) and compliance of iron tablets consumption (p = 0.001; OR = 3.46) related with anemia. Pregnant women who didn’t regularly visit ANC had 4 times greater risk of anemia, while non-comliance pregnant women consume iron tablets had 3,46 times greater risk of anemia.Conclusion: The regularity of ANC visits and compliance to iron tablet consumption were related to anemia in third trimester pregnant women.ABSTRAKLatar Belakang: Anemia selama kehamilan merupakan faktor risiko bagi kesehatan ibu dan janin. Pemerintah telah menerapkan distribusi tablet Fe untuk ibu hamil sebagai upaya pencegahan anemia selama kehamilan. Masalah timbul akibat ketidakteraturan ANC dan ketidakpatuhan ibu hamil dalam mengonsumsi tablet Fe.Tujuan: Tujuan penelitian untuk menganalisis hubungan keteraturan kunjungan Antenatal Care (ANC) dan kepatuhan konsumsi tablet Fe dengan kejadian anemia pada ibu hamil trimester IIIMetode: Menggunakan desain studi case controldengan besar sampel 30 yang terdiri dari 15 kasus dan 15 kontrol diambil dengan metode simple random sampling. Penelitian ini menghubungkan keteraturan kunjungan Antenatal Care (ANC) dan kepatuhan konsumsi tablet Fe dengan kejadian anemia pada ibu hamil trimester III.Penelitian dilakukan di wilayah kerja Puskesmas Maron Kabupaten Probolinggo pada bulan Mei–Agustus 2018. Analisis data yang digunakan adalah chi- square.Hasil: Hasil penelitian menunjukkan terdapat hubungan antara keteraturan kunjungan Antenatal Care (ANC) (p=0,001; OR=4) dan kepatuhan konsumsi tablet Fe (p=0,001; OR=3,46) dengan kejadian anemia. Ibu hamil yang tidak teratur melakukan kunjungan ANC memiliki risiko 4 kali lebih besar untuk mengalami anemia, sedangkan ibu hamil yang tidak patuh mengonsumsi tablet Fe berisiko 3,46 kali lebih besar untuk mengalami anemia.Kesimpulan: Keteraturan kunjungan ANC dan kepatuhan konsumsi tablet Fe berhubungan dengan kejadian anemia pada ibu hamil trimester III.

scholarly journals Transmission of SARS-CoV-2 infection mother to the newborn

2020 ◽  
Vol 7 (10) ◽  
pp. 2086
Author(s):  
Bonifacio Caballero ◽  
Daniel Caballero
Keyword(s):  
Virus Infection ◽  
Pregnant Women ◽  
Vertical Transmission ◽  
Intrauterine Infection ◽  
Late Pregnancy ◽  
Hubei Province ◽  
Capital City ◽  
Third Trimester ◽  
The Third ◽  
The World

The emergence of the new corona virus infection that occurred in Wuhan, the capital city of China's Hubei province in December 2019 initially labeled 2019-nCoV and later named SARS-CoV-2, has spread in several countries around the world and subsequently raised concerns about the possibility of vertical transmission from the mother to the fetus, producing its disease named COVID-19. Around 12 articles about pregnant women infected with COVID-19 and their newborns have been published between February 10 and April 4, 2020. So far, there are few reports on newborns. There is currently evidence of vertical transmission from pregnant women with COVID-19 infection during the third trimester. The results of this report suggest that currently there is evidence of intrauterine infection caused by vertical transmission in women who develop COVID-19 pneumonia and die in late pregnancy. However, most of these newborns have been asymptomatic or mildly symptomatic, but as the outbreak and information are changing rapidly, it is recommended to continue to check for updates.

scholarly journals Meningkatkan Hemoglobin pada Ibu Hamil Trimester III dengan Rebusan Bunga Rosella

2020 ◽  
Vol 2 (3) ◽  
pp. 163-169
Author(s):  
Rifi Wulandari
Keyword(s):  
Pregnant Women ◽  
T Test ◽  
Control Group ◽  
P Value ◽  
Third Trimester ◽  
Control Group Design ◽  
Anemia During Pregnancy ◽  
The Mean ◽  
And Control ◽  
Pregnant Mothers

Anemia during pregnancy is one of the most common disorders in pregnant women in Indonesia. Rosella (Hibiscus sabdariffa) is considered able to increase the hemoglobin levels in pregnant mothers. To analyze the effect of Rosella flower on the increase of Hemoglobin level in pregnant women receiving Fe tablet. This study was a quasi-experiment with a pretest-posttest control group design. 32 participants were selected using accidental sampling, which assigned in the experiment and control group. All samples were pregnant women in the third trimester and receiving iron tablets. Independent t-test and paired t-test were used for data analysis. The result indicated that there was an increase in hemoglobin levels in both the experiment and the control group. The mean increase of hemoglobin levels in the control group was 0.59gr and in the experiment group was 1.11. The hemoglobin levels in the experiment group were higher than the levels in the control group. Independent t-test obtained a p-value of 0.241 indicating that there wasn’t a significant mean difference of hemoglobin levels between the control group and the treatment group. The consumption of rosella combined with Fe tablet showed a significant increase of hemoglobin levels compared to pregnant women. Therefore, it is suggested for midwives to use the result of this research as evidence-practice through counseling for pregnant mothers about the utilization of rosella that can increase hemoglobin levels in pregnant.

Safety and Immunogenicity of a Respiratory Syncytial Virus Fusion (F) Protein Nanoparticle Vaccine in Healthy Third-Trimester Pregnant Women and Their Infants

2019 ◽  
Vol 220 (11) ◽  
pp. 1802-1815 ◽  
Author(s):  
Flor M Muňoz ◽  
Geeta K Swamy ◽  
Somia P Hickman ◽  
Sapeckshita Agrawal ◽  
Pedro A Piedra ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Pregnant Women ◽  
Specific Antibody ◽  
Post Partum ◽  
Study Groups ◽  
Third Trimester ◽  
F Protein ◽  
Before And After ◽  
Syncytial Virus ◽  
Tract Disease

Abstract Background Respiratory syncytial virus (RSV) is the leading cause of infant lower respiratory tract disease and hospitalization worldwide. Methods Safety and immunogenicity of RSV fusion (F) protein nanoparticle vaccine or placebo were evaluated in 50 healthy third-trimester pregnant women. Assessments included vaccine tolerability and safety in women and infants, and RSV-specific antibody measures in women before and after vaccination, at delivery and post partum. Results The vaccine was well tolerated; no meaningful differences in pregnancy or infant outcomes were observed between study groups. RSV-specific antibody levels increased significantly among vaccine recipients, including responses competitive with well-described monoclonal antibodies specific for multiple RSV neutralizing epitopes. No significant antibody increase was seen among placebo recipients, although a shallow upward trend across the RSV season was noted. Transplacental antibody transfer was 90%–120% across assays for infants of vaccinated women. Women with an interval of ≥30 days between vaccination and delivery demonstrated higher placental antibody transfer rates than women with an interval <30 days. Half-lives of RSV-specific antibodies in infants approximated 40 days. There was no evidence of severe RSV disease in infants of vaccinated mothers. Conclusions Data from this phase 2 study support a maternal immunization strategy to protect infants from RSV disease. Clinical Trials Registration NCT02247726.

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