Epidemiological Characteristics of Major Depression of Hospitalized Patients in Psychiatric Hospital “Demir Hisar” – Demir Hisar for a Five Year Period from 2013 to 2017

BACKGROUND: Severe depression is a mental disorder with a wide range of changes in psychic functions, primarily of affectivity, and is manifested by dysphoric mood and reductive changes in cognitive, conative, and other psychic dynamics, with the presence of psychosomatic complaints and suicidal thoughts. There is always a triad of symptoms: Alteration of affectivity, anhedonia, and low energy with fatigue, but in her clinical picture, there are other symptoms, such as feeling guilty and helpless, obsessed with “black thoughts” with loss of confidence in themselves, with hopelessness, loss of appetite, and weight loss with present insomnia or hypersomnia, and more frequent thinking about death due to the feeling of worthlessness of life. This mental illness covers a vast area of the affective life of a human with a broad spectrum classified by ICD - 10- F 32, F 32.2, and F 32.3. AIM: The main goal is to determine the total number of patients with the major depression treated at “Demir Hisar” Psychiatric Hospital for a period of 5 years, retrospectively in 2013 until 2017 and to determine the impact of socio-demographic variables as risk factors and predictors. METHODS: The study is retrospective, and the necessary parameters for achieving the goals of the research are provided by analyzing the medical histories of all hospitalized patients treated in psychiatric hospitals Demir Hisar in the period from 2013 to 2017. Incidence rates and indexes of the dynamics of hospitalized patients with major depression were determined. RESULTS: About 61.8% of the patients are men and 38.2% women. Patients with no education and elementary school were 64.5% versus patients with high school and university 35.5% and are significantly underpowered. Regarding the employment status, 38.2% of patients are unemployed, and 61.8% of patients are employed. According to the cross-sectional study, 64.7% of men without education have severe depression and live in the city, and 53.3% of women with secondary education live in urban areas (city), meaning rural residence is associated with a reduced rate of severe depression. CONCLUSION: We can conclude that socio-demographic characteristics – age, gender, marital status, level of education, employment/unemployment status, and place of residence are related to the severity of depression.

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Epidemiological Characteristics of Great Depression Diseases of Hospitalized Patients in Psychiatric Hospital “Negorci” for a Five-Year Period From 2013 to 2017

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2020.3642 ◽

2020 ◽

Vol 8 (E) ◽

pp. 150-155

Author(s):

Iliev Biljana ◽

Dimitar Bonevski ◽

Andromahi Naumovska

Keyword(s):

Psychiatric Hospital ◽

Mutual Influence ◽

Severe Depression ◽

Large Area ◽

Number Of Patients ◽

Wide Range ◽

Motor Activities ◽

Icd 10 ◽

Negative Effect ◽

Epidemiological Characteristics

BACKGROUND: Severe depression beside the pathological mood also denotes the cognitive, perceptual, and motor activities that are psychopathologically related to the scope of all psychic dynamics, which means cognitive, conative, and emotional. This mental illness covers a large area of the affective life of a man with a wide range of severe depression classified by ICD-10 – F32, F32.2, and F32.3 . With retrospective approach to research from medical history collects data on biological and social factors that have a positive or negative effect on the onset and course of severe depression. AIM: The research aims to determine the total number of patients with severe depression treated in hospital conditions in the Psychiatric Hospital “Negorci” – Negorci for a period of 5 years from 2013 to 2017 to get a clear picture of the factors and specific predictors that lead to the development of severe depression. METHODS: Within the research methods, all the parameters contained are calculated so that it can be concluded that the predictors influence and differ from other stakeholders responsible for etiopathogenesis, although they have a mutual influence. RESULTS: According to the current study, patients with severe depression were found to have an increased frequency between 45 and 62 years. The mean age of the respondents was 52.14 years. According to the level of education, the majority (49%) of the patients have completed primary education and the least with higher education, i.e., only 2 (3.1%). CONCLUSION: From the obtained data, it was obtained the scope of the influence of sociodemographic data on the occurrence of severe depression and sequelae of the disease.

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An epidemiological study of concomitant use of herbal medicine and antipsychotics in schizophrenic patients: implication for herb-drug interaction

European Psychiatry ◽

10.1016/s0924-9338(11)73240-0 ◽

2011 ◽

Vol 26 (S2) ◽

pp. 1536-1536

Author(s):

Z.-J. Zhang

Keyword(s):

Herbal Medicine ◽

Clinical Outcomes ◽

Epidemiological Study ◽

Urban Areas ◽

Psychiatric Hospitals ◽

Adverse Outcomes ◽

Antipsychotic Treatment ◽

Clinical Effects ◽

Association Analyses ◽

Number Of Patients

Herb-drug interactions are an important issue in drug safety and clinical practice. The aim of this epidemiological study was to characterize associations of clinical outcomes with concomitant herbal and antipsychotic use in patients with schizophrenia. A total of 1795 patients with schizophrenia who were randomly selected from 17 psychiatric hospitals in China were interviewed face-to-face using a structured questionnaire. Association analyses were conducted to examine correlates between Chinese medicine (CM) use and demographic, clinical variables, antipsychotic medication mode, and clinical outcomes. The prevalence of concomitant CM and antipsychotic treatment was 36.4% [95% confidence interval (95% CI) 34.2%–38.6%]. Patients using concomitant CM had a significantly greater chance of improved outcomes than non-CM use (61.1% vs. 34.3%, OR = 3.44, 95% CI 2.80–4.24). However, a small but significant number of patients treated concomitantly with CM had a greater risk of developing worse outcomes (7.2% vs. 4.4%, OR = 2.06, 95% CI 2.06–4.83). Significant predictors for concomitant CM treatment-associated outcomes were residence in urban areas, paranoid psychosis, and exceeding 3 months of CM use. Herbal medicine regimens containing Radix Bupleuri, Fructus Gardenia, Fructus Schisandrae, Radix Rehmanniae, Akebia Caulis, and Semen Plantaginis in concomitant use with quetiapine, clozapine, and olanzepine were associated with nearly 60% of the risk of adverse outcomes. Our study suggests that concomitant herbal and antipsychotic treatment could produce either beneficial or adverse clinical effects in schizophrenic population. Potential herb-drug pharmacokinetic interactions need to be further evaluated.

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IMPACT OF DIGITAL MARKETING: THE PRESENT SCENARIO IN TELANGANA STATE – AN EMPERICAL STUDY

Scholarly Research Journal for Interdisciplinary Studies ◽

10.21922/srjis.v8i65.1575 ◽

2021 ◽

Vol 8 (65) ◽

pp. 15164-15172

Author(s):

S. Pratap ◽

Aziz Fatima

Keyword(s):

Rural Areas ◽

Urban Areas ◽

Digital Marketing ◽

Rural And Remote ◽

Remote Areas ◽

Wide Range ◽

Rural And Remote Areas ◽

Telangana State ◽

The Impact ◽

Made In

In present scenario of COVID-19, the effect of pandemic on Digital Marketing is visible not only in urban areas but also in rural areas. Customers are searching for various products and services through Google by which they can purchase wide range of products and services to fill their needs and desires at relatively low price. The freedom to select numerous products is available by browsing various websites. Hence this study focuses on Impact of digital marketing particularly in the selected rural areas of Telangana state. This state been formed recently but in the IT sector it is receiving much attention throughout the globe, as many MNC’s are establishing their operations in this state. Therefore, an attempt has been made in this study to find out how the Impact of digital marketing is trickling down in the rural and remote areas of newly formed Telangana state. Hence this study focuses the impact of digital marketing in the selected areas of Telangana state.

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Impact of COVID-19 Pandemic on the Incidence, Prehospital Evaluation, and Presentation of Ischemic Stroke at a Nonurban Comprehensive Stroke Center

Stroke Research and Treatment ◽

10.1155/2021/6624231 ◽

2021 ◽

Vol 2021 ◽

pp. 1-5

Author(s):

Cesar Velasco ◽

Brandon Wattai ◽

Scott Buchle ◽

Alicia Richardson ◽

Varun Padmanaban ◽

...

Keyword(s):

Urban Areas ◽

Stroke Care ◽

Final Diagnosis ◽

Medical Attention ◽

Presenting Symptoms ◽

Number Of Patients ◽

Community Transmission ◽

Comprehensive Stroke Center ◽

Stroke Center ◽

The Impact

Introduction. Many reports have described a decrease in the numbers of patients seeking medical attention for typical emergencies during the COVID-19 pandemic. These reports primarily relate to urban areas with widespread community transmission. The impact of COVID-19 on nonurban areas with minimal community transmission is less well understood. Methods. Using a prospectively maintained prehospital quality improvement database, we reviewed our hospital EMS transports with a diagnosis of stroke from January to April 2019 (baseline) and January to April 2020 (pandemic). We compared the volume of patients, transport/presentation times, severity of presenting symptoms, and final diagnosis. Results. In January, February, March, and April 2019, 10, 11, 17, and 19 patients, respectively, were transported in comparison to 19, 14, 10, and 8 during the same months in 2020. From January through April 2019, there was a 53% increase in transports, compared to a 42% decrease during the same months in 2020, constituting significantly different trend-line slopes (3.30; 95% CI 0.48–6.12 versus -3.70; 95% CI -5.76–-1.64, p = 0.001 ). Patient demographics, comorbidities, and symptom severity were mostly similar over the two time periods, and the number of patients with a final diagnosis of stroke was also similar. However, the median interval from EMS dispatch to ED arrival for patients with a final diagnosis of stroke was significantly longer in January to April 2020 ( 50 ± 11.7 min ) compared to the same time period in 2019 ( 42 ± 8.2 min , p = 0.01 ). Discussion/Conclusion. Our data indicate a decrease in patient transport volumes and longer intervals to EMS activation for suspected stroke care. These results suggest that even in a nonurban location without widespread community transmission, patients may be delaying or avoiding care for severe illnesses such as stroke. Clinicians and public health officials should not ignore the potential impact of pandemic-like illnesses even in areas of relatively low disease prevalence.

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Compound Sarcopenia in Hospitalized Patients with Cirrhosis Worsens Outcomes with Increasing Age

Nutrients ◽

10.3390/nu13020659 ◽

2021 ◽

Vol 13 (2) ◽

pp. 659

Author(s):

Nicole Welch ◽

Amy Attaway ◽

Annette Bellar ◽

Hayder Alkhafaji ◽

Adil Vural ◽

...

Keyword(s):

Chronic Diseases ◽

Older Patients ◽

Hospitalized Patients ◽

Muscle Loss ◽

Term Care ◽

Old Patients ◽

Younger Patients ◽

Age Related ◽

Number Of Patients ◽

The Impact

Background: There are limited data on outcomes of older patients with chronic diseases. Skeletal muscle loss of aging (primary sarcopenia) has been extensively studied but the impact of secondary sarcopenia of chronic disease is not as well evaluated. Older patients with chronic diseases have both primary and secondary sarcopenia that we term compound sarcopenia. We evaluated the clinical impact of compound sarcopenia in hospitalized patients with cirrhosis given the increasing number of patients and high prevalence of sarcopenia in these patients. Design: The Nationwide Inpatients Sample (NIS) database (years 2010–2014) was analyzed to study older patients with cirrhosis. Since there is no universal hospital diagnosis code for “muscle loss”, we used a comprehensive array of codes for “muscle loss phenotype” in the international classification of diseases-9 (ICD-9). A randomly selected 2% sample of hospitalized general medical population (GMP) and inpatients with cirrhosis were stratified into 3 age groups based on age-related changes in muscle mass. In-hospital mortality, length of stay (LoS), cost of hospitalization (CoH), comorbidities and discharge disposition were analyzed. Results. Of 517,605 hospitalizations for GMP and 106,835 hospitalizations for treatment of cirrhosis or a cirrhosis-related complication, 207,266 (40.4%) GMP and 29,018 (27.7%) patients with cirrhosis were >65 years old, respectively. Muscle loss phenotype in both GMP and inpatients with cirrhosis 51–65 years old and >65 years old was significantly (p < 0.001 for all) associated with higher mortality, LoS, and CoH compared to those ≤50 years old. Patients >65 years old with cirrhosis and muscle loss phenotype had higher mortality (adjusted OR: 1.06, 95% CI [1.04, 1.08] and CoH (adjusted odds ratio (OR): 1.10, 95% confidence interval (CI) [1.04, 1.08])) when compared to >65 years old GMP with muscle loss phenotype. Muscle loss in younger patients with cirrhosis (≤50 years old) was associated with worse outcomes compared to GMP >65 years old. Non-home discharges (nursing, skilled, long-term care) were more frequent with increasing age to a greater extent in patients with cirrhosis with muscle loss phenotype for each age stratum. Conclusion: Muscle loss is more frequent in older patients with cirrhosis than younger patients with cirrhosis and older GMP. Younger patients with cirrhosis had clinical outcomes similar to those of older GMP, suggesting an accelerated senescence in cirrhosis. Compound sarcopenia in older patients with cirrhosis is associated with higher inpatient mortality, increased LoS, and CoH compared to GMP with sarcopenia.

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Collateral effects of the coronavirus disease 2019 pandemic on lung cancer diagnosis in Korea

BMC Cancer ◽

10.1186/s12885-020-07544-3 ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Ji Young Park ◽

Ye Jin Lee ◽

Taehee Kim ◽

Chang Youl Lee ◽

Hwan Il Kim ◽

...

Keyword(s):

Lung Cancer ◽

Cancer Diagnosis ◽

Rapid Progression ◽

Lung Cancers ◽

The Past ◽

Lung Cancer Diagnosis ◽

Number Of Patients ◽

Wide Range ◽

Collateral Effects ◽

The Impact

Abstract Background The COVID-19 pandemic is predicted to significantly affect patients with lung cancer, owing to its rapid progression and high mortality. Studies on lung cancer diagnosis and treatment during an epidemic are lacking. We analyzed the impact of COVID-19 on lung cancer diagnosis in Korea, where lung cancer incidence continues to rise. Methods The number of newly diagnosed lung cancer cases in three university-affiliated hospitals during the pandemic and their clinical features were compared with lung cancer cases diagnosed during the same period in the past 3 years. The effectiveness of measures taken by the study hospitals to prevent nosocomial transmission was reviewed. Results A total of 612 patients were diagnosed with lung cancer from February through June, 2017–2020. During the pandemic, the number of patients who sought consultation at the division of pulmonology of study hospitals dropped by 16% from the previous year. Responding to the pandemic, the involved hospitals created physically isolated triage areas for patients with acute respiratory infection symptoms. Wide-range screening and preventive measures were implemented, thus minimizing the delay in lung cancer diagnosis. No patient acquired COVID-19 due to hospital exposure. The proportion of patients with stage III–IV non-small-cell lung cancer (NSCLC) significantly increased (2020: 74.7% vs. 2017: 57.9%, 2018: 66.7%, 2019: 62.7%, p = 0.011). The number of lung cancers diagnosed during this period and the previous year remained the same. Conclusions The proportion of patients with advanced NSCLC increased during the COVID-19 pandemic.

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The Impact of Depression on Patient Outcomes in Hip Arthroscopic Surgery

Orthopaedic Journal of Sports Medicine ◽

10.1177/2325967118806490 ◽

2018 ◽

Vol 6 (11) ◽

pp. 232596711880649 ◽

Cited By ~ 11

Author(s):

RobRoy L. Martin ◽

John J. Christoforetti ◽

Ryan McGovern ◽

Benjamin R. Kivlan ◽

Andrew B. Wolff ◽

...

Keyword(s):

Rating Scale ◽

Arthroscopic Surgery ◽

Severe Depression ◽

Outcome Data ◽

Labral Repair ◽

Initial Assessment ◽

Symptoms Of Depression ◽

Number Of Patients ◽

The Impact

Background: Mental health impairments have been shown to negatively affect preoperative self-reported function in patients with various musculoskeletal disorders, including those with femoroacetabular impingement. Hypothesis: Those with symptoms of depression will have lower self-reported function, more pain, and less satisfaction on initial assessment and at 2-year follow-up than those without symptoms of depression. Study Design: Cohort study; Level of evidence, 3. Methods: Patients who were enrolled in a multicenter hip arthroscopic surgery registry and had 2-year outcome data available were included in the study. Patients completed the 12-item International Hip Outcome Tool (iHOT-12), visual analog scale (VAS) for pain, and 12-item Short-Form Health Survey (SF-12) when consenting for surgery. At 2-year follow-up, patients were emailed the iHOT, the VAS, and a rating scale of surgical satisfaction. Initial SF-12 mental component summary (MCS) scores <46.5 and ≤36 were used to qualify symptoms of depression and severe depression, respectively, as previously described and validated. Repeated-measures analysis of variance was performed to compare preoperative and 2-year postoperative iHOT-12, VAS, and satisfaction scores between those with and without symptoms of depression. Results: A total of 781 patients achieved the approximate 2-year milestone (mean follow-up, 735 ± 68 days), with 651 (83%) having 2-year outcome data available. There were 434 (67%) female and 217 (33%) male patients, with a mean age of 35.8 ± 13.0 years and a mean body mass index of 25.4 ± 8.8 kg/m2. The most common procedures were femoroplasty (83%), followed by synovectomy (80%), labral repair (76%), acetabuloplasty (58%), acetabular chondroplasty (56%), femoral chondroplasty (23%), and labral reconstruction (19%). The mean initial SF-12 MCS score was 51.5 ± 10.3, with cutoff scores indicating symptoms of depression and severe depression in 181 (28%) and 71 (11%) patients, respectively. Patients with symptoms of depression scored significantly ( P < .05) lower on the initial iHOT-12 and VAS and 2-year follow-up iHOT-12, VAS, and rating scale of surgical satisfaction. Conclusion: A large number of patients who underwent hip arthroscopic surgery presented with symptoms of depression, which negatively affected self-reported function, pain levels, and satisfaction on initial assessment and at 2-year follow-up. Surgeons who perform hip arthroscopic surgery may need to identify the symptoms of depression and be aware of the impact that depression can have on surgical outcomes.

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The impact of panic-agoraphobic comorbidity on suicidality in hospitalized patients with major depression

Depression and Anxiety ◽

10.1002/da.20609 ◽

2010 ◽

Vol 27 (3) ◽

pp. 310-315 ◽

Cited By ~ 18

Author(s):

Lily A. Brown ◽

Brandon A. Gaudiano ◽

Ivan W. Miller

Keyword(s):

Major Depression ◽

Hospitalized Patients ◽

The Impact

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Fungi causing powdery mildew on plants of a Botanical Garden in Southern Finland

Karstenia ◽

10.29203/ka.2021.507 ◽

2021 ◽

pp. 13-29

Author(s):

Ville J. Heiskanen ◽

Jari P. T. Valkonen

Keyword(s):

Powdery Mildew ◽

Urban Areas ◽

Biological Diversity ◽

Morphological Characteristics ◽

Cultivated Plants ◽

Its Sequencing ◽

Species Determination ◽

Morphological Studies ◽

Wide Range ◽

The Impact

Fungi that cause powdery mildew on plants are plant pathogenic parasites (<em>Erysiphales</em>) and can significantly reduce the ornamental value of plants and cause significant yield losses among cultivated plants. In this study, 94 plant accessions infected with powdery mildew were observed in Kumpula Botanic Garden, Helsinki, Finland, in 2015. The taxonomic affiliation and species richness of powdery mildew fungi were investigated. Morphological studies by microscope distinguished only 14 fungal species, whereas further comparisons of internal transcribed spacer (ITS) sequences enabled the identification of 28 species. Hence, ITS sequencing improved the reliability of species determination, as compared with the use of morphological characteristics only. The vegetation in an area of six hectares supported a wide range of fungi that cause powdery mildew as well as hyperparasitic microbes, which may balance the impact of pathogens in host plants. The findings of this study emphasize the role of botanical gardens in protecting biological diversity in urban areas.

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Clinical and Epidemiological Characteristics of the Contingent of Elderly in-Patients in a Frame of the Modern Model of Psychogeriatric Care

Psychiatry ◽

10.30629/2618-6667-2021-19-1-26-33 ◽

2021 ◽

Vol 19 (1) ◽

pp. 26-33

Author(s):

V. G. Rotshtein ◽

V. V. Ryakhovskiy ◽

A. E. Shtinov

Keyword(s):

Mental Health ◽

Psychiatric Hospital ◽

Health Research ◽

Psychiatric Care ◽

Psychiatric Service ◽

Psychiatric Hospitals ◽

Mental Health Research ◽

Research Centre ◽

Moscow City ◽

Epidemiological Characteristics

Background: a system of reforming of psychiatric care in Russia has led to a reduction of beds in psychiatric hospitals. At the same time it is known about permanent high need among elderly patients in the appropriate psychiatric care. In this regard, it became necessary to study the adequacy of the assistance provided to the needs of patients.The aim of the research: to investigate and compare clinic-epidemiological characteristics of the contingent of the elderly and senile inpatients in the city psychiatric care system and at the research institution.Materials and methods: as a material for the research served data from the reports from Moscow Clinical Psychiatric Hospital #13 (MCPH #13) and the clinic of Mental Health Research Centre (MHRC) about the patients older than 65 treated in 2017–2018.The results: this article contains comparative data about contingents of elderly psychiatric in-patients treated in the Moscow City Clinical Psychiatric Hospital #13 and in the Mental Health Research Center (MHRC). Collation of the indicated contingents allowed to determine that city psychiatric care satisfactorily meets needs of the severe psychiatric patients older than 65. However the experience of the clinic of the MHRC differs. This clinic has some peculiarities: it does not use involuntary hospitalization and it gives preference to difficult cases, where diagnosis is unclear, and where there is a challenge to find an appropriate treatment regimen; patients that require special care are also rarely admitted. This experience indicates that there is significant number of cases when hospitalization of patients with moderate mental disorders is also absolutely necessary. The majority of such cases consists of patients, suffering with depression and the necessity of their admission is dictated by the impossibility to adjust proper therapy in out- patient care.Conclusion: the contemporary Moscow city psychiatric service do not meet needs of the discussed category of patients for inpatient care. Whether it is necessary to improve it, or to provide this niche to scientific and commercial institutions is a matter of further research.

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