scholarly journals Association between Foxp3 Tumor Infiltrating Lymphocyte Expression and Response After Chemoradiation in Nasopharyngeal Carcinoma

2021 ◽  
Vol 9 (A) ◽  
pp. 1285-1291
Author(s):  
Lisnawati Lisnawati ◽  
Yayi Dwina Billianti ◽  
Amelia Fossetta Manatar
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Treatment Response ◽  
Foxp3 Expression ◽  
Cross Sectional Study ◽  
Surface Epithelium ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Significant Difference ◽  
The Relationship ◽  
Anatomical Pathology

BACKGROUND: Nasopharyngeal carcinoma (NPC) is a carcinoma originating from the surface epithelium of the nasopharynx with the highest incidence in China and South East Asia. Currently, many researchers are developing tumor microenvironment which can be assessed by tumor-infiltrating lymphochyte, and its association with treatment response in several tumors, including NPC. Foxp3, known as a regulatory T cell (Treg) marker, plays a role in the immunoregulatory environment of tumor cells and can be used as a prognostic factor. The relationship between Foxp3 expression and treatment response is considered as one of the factors affecting the prognosis of NPC. AIM: This study aims to determine the relationship between Foxp3 expression and treatment response in NPC. MATERIALS AND METHODS: A cross-sectional study was done to analyze the association between Foxp3 and treatment response in NPC. This study included 60 samples who were diagnosed with non-keratinizing NPC at the Department of Anatomical Pathology, Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo Hospital from January 2018 until December 2020. Immunohistochemistry was done to evaluate the expression of Foxp3. Foxp3 expression was evaluated in the intratumoral and peritumoral areas. RESULTS: Among 60 patients, the number of males were more than females (66.7%, 33.3%, respectively) with a ratio of 2:1. There was statistically significant difference between intratumoral and total Foxp3 expression and treatment response (p < 0.05, p = 0.001, respectively); however, no significant differences found between peritumoral Foxp3 expression and treatment response (p = 0.114). CONCLUSION: Foxp3 expression had a statistically significant relationship with response therapy after chemoradiation.

scholarly journals HUBUNGAN KADAR VITAMIN D DALAM DARAH DENGAN KEJADIAN OBESITAS PADA SISWA SMA PEMBANGUNAN PADANG

2019 ◽  
Vol 8 (1) ◽  
pp. 1
Author(s):  
Sesmi Nanda Oktavia
Keyword(s):  
Vitamin D ◽  
Body Height ◽  
Simple Random Sampling ◽  
Cross Sectional Study ◽  
Elisa Method ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
The Relationship

The obesity cases in the world, including Indonesia is increasing. This condition also occurs to senior high school (SMA) Pembangunan students in Padang. There are several factors affecting the obesity occurrence, one them is the level of vitamin D serum. The aims of this study was to identify the relationship between vitamin D levels in the blood and the obesity occurrence.This research used cross sectional study design from March to June 2017. The samples were 82 students from SMA Pembangunan in Padang conducted by using simple random sampling. The level of obesity was determined by measuring body height and weight. The z zscore BMI/age was calculated by using the WHO antro-plus program while the vitamin D level was measured by ELISA method. The statistical analysis used independent sample t-test.The result shows that there is significant difference of the average vitamin D level in the blood of students with obesity compared to normal students (p=0,025). There is also difference in proportion of obesity occurence between the respondents who lack Vitamin D compared to those with adequate level of vitamin D (p=0,020).Based on the research, it is concluded that there is significant relationship between the level of vitamin D in the blood and the occurrence of obesity. Suggestion further research on the effect of vitamin D on obesity needs to be conducted.

The Relationship of Mode and Intensity of Training on Resting Metabolic Rate in Women

2001 ◽  
Vol 11 (1) ◽  
pp. 1-14 ◽  
Author(s):  
Heidi K. Byrne ◽  
Jack H. Wilmore
Keyword(s):  
Metabolic Rate ◽  
Resting Metabolic Rate ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Women Subjects ◽  
Present Cross Sectional Study ◽  
Significant Difference ◽  
Level Of Training ◽  
The Relationship ◽  
Aerobically Trained

The present cross-sectional study was designed to investigate the relationship between exercise training and resting metabolic rate (RMR). The focus of this investigation was to compare RMR in aerobically trained (AT), resistance trained (RT), and untrained (UNT) women. Subjects were also classified as highly trained (HT), moderately trained (MT), or untrained (UNT) in order to examine the relationship between RMR and level of training. Sixty-one women between the ages of 18 and 46 years volunteered to serve as subjects in this study. Each subject completed measurements of body composition, maximal oxygen uptake (V̇O2max), and two consecutive measurements of RMR. The data presented show that there was no significant difference in resting metabolic rate between resistance-trained, aerobically trained, and control subjects. However, when grouped by intensity of training, there was a trend for an increased resting metabolic rate (kcal/day) in the highly trained subjects, regardless of mode of training.

Determination Of Factors Affecting Father-Baby Attachment

2021 ◽  
Vol 6 (14) ◽  
pp. 1-7
Author(s):  
Emine Serap ÇAĞAN ◽  
Birsen KARACA SAYDAM ◽  
Sinem GÜLÜMSER ATEŞ ◽  
Rabia EKTİ GENÇ ◽  
Esin ÇEBER TURFAN
Keyword(s):  
Cross Sectional Study ◽  
Study Data ◽  
Cross Sectional ◽  
Infant Attachment ◽  
Factors Affecting ◽  
Attachment Figure ◽  
Gynecology And Obstetrics ◽  
Significant Difference ◽  
Package Program ◽  
The Difference

Introduction: The primary attachment figure is mostly defined as the mother, and studies focus on the mother. However, in many babies, basic attachment is just as good with the father as with the mother. It is seen that there are very few studies in the literature investigating the correlations of father-infant attachment relationships.. The aim of this study is to determine the father-infant attachment status and to determine the factors affecting attachment. Method: The population of the cross-sectional study consisted of the spouses of all puerperant women hospitalized in the Gynecology and Obstetrics Clinic between September 1, 2018 and October 1, 2018. The sample size consisted of 156 fathers who agreed to participate in the study. Father identification form and father-infant attachment scale were used to collect the study data. The analysis of the data obtained from the research was carried out on the computer using the SPSS 16.0 package program. Results: 156 fathers participated in the study. The mean age of the fathers is 33.64±6.49, and 38.5% of them have a bachelor's degree. 91.0% of fathers stated that they felt ready for fatherhood. The fathers' Father-Infant Attachment Scale mean score was 82.60±7.72 In the analysis, the difference between the variables and the total score of the scale was found to be statistically insignificant (p>0.05). Discussion and Conclusion: At the end of the study, the bonding process of fathers participating in the study with their babies and the factors affecting this process were evaluated and it was seen that the father-infant attachment scale mean scores of the fathers participating in the study were high and were similar to other studies. In addition, when the basic factors affecting father-infant attachment were compared with the attachment scale mean score, it was found that there was no statistically significant difference.

scholarly journals Factors affecting academic failure in medical students in Iran

2021 ◽  
Vol 10 (1) ◽  
pp. 14-14
Author(s):  
Zohreh Tajabadi ◽  
Matineh Sadat Miri ◽  
Soliman Ahmadi ◽  
Matineh Pourrahimi ◽  
Mojtaba Abdi ◽  
...  
Keyword(s):  
Student Satisfaction ◽  
Academic Failure ◽  
Educational Status ◽  
Cross Sectional Study ◽  
Academic Probation ◽  
Affecting Factors ◽  
Cross Sectional ◽  
Significance Level ◽  
Factors Affecting ◽  
Significant Difference

Background: Students are considered part of the capital of each country. Several factors can affect their educational status and, as a result, contribute to their academic failure. The current study seeks to investigate the relationship between students’ academic failure and the affecting factors with the Iranian Educational Ranking of Universities. Methods: This is a descriptive cross-sectional study. The required sample size was calculated using Cochran’s formula. A researcher-made questionnaire with 5 parts was used to collect data. Kruskal Wallis and Spearman’s analysis of variance was used for analysis. The significance level was considered as 0.05. Results: A total of 1215 people participated; 13.7% of students had had an academic failure and 2.0% of them were on academic probation. There was a correlation between university RAD rank and academic failure (r = -0.098 and P = 0.0001) as well as student satisfaction (r = 0.264 – P = 0.0001). There was a significant difference between an academic drop and academic grade in three ranks of university (Pv= 0.0001), and, interestingly, having moved from Rank 1 to 3, having academic grade increases, and having academic failure decreases. Conclusion: According to the findings of this study, the higher ranked the college campus is on the RAD scale, the higher the academic failure rate. For annual assessment of universities, it is proposed that assessment of academic failure and grades be used as a benchmark.

Women’s Participation in Self-Care and the Importance of Paying Attention to Cultural Capital: A Cross-Sectional Study among Women in Yazd (Iran)

2021 ◽  
pp. 0272684X2110334
Author(s):  
Hamideh Shiri Mohammadabad ◽  
Seyed Alireza Afshani
Keyword(s):  
Cultural Capital ◽  
Structural Equation ◽  
Self Care ◽  
Cross Sectional Study ◽  
Fit Indices ◽  
Cross Sectional ◽  
Equation Modelling ◽  
Women's Participation ◽  
Significant Difference ◽  
The Relationship

The present study aimed to investigate the relationship between women's cultural capital and self-care. A survey was employed with a sample size of 737 women living in the marginal, middle, and upper areas of Yazd in terms of socioeconomic characteristics. Data were analyzed using structural equation modelling by SPSS and Amos version 24. The results revealed that the effect of cultural capital on self-care was positive and significant (β = 0.46, p < 0.001). The effectiveness rates of cultural capital on women's self-care in the marginal, middle, and upper areas were 0.44, 0.32 and 0.45, respectively (p < 0.001). Besides, there was no significant difference between the intensity of the relationship between cultural capital and self-care in the three areas (CR < 1.96). The fit indices also indicated that the model had a good fit (CMIN/DF = 2.560, NFI = 0.916, RMSEA = 0.033, CFI = 0.946, TLI = 0.922, GFI = 0.963, IFI = 0.947).

scholarly journals The relationship between premenstrual syndrome and anger

2019 ◽  
Vol 35 (2) ◽  
Author(s):  
Havva Yeşildere Sağlam ◽  
Fatma Basar
Keyword(s):  
Premenstrual Syndrome ◽  
Personal Information ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
Anger Control ◽  
Cross Sectional ◽  
Creative Commons ◽  
Syndrome Scale ◽  
Significant Difference ◽  
The Relationship

Objective: Premenstrual Syndrome (PMS) is a significant disorder affecting the daily life of women of reproductive age. The aims of this study was to determine the PMS prevalence and the examination of the relationship between PMS and anger. Methods: This was a cross sectional study. The study was carried out with 720 women between the ages of 15-49 living in the province of Kutahya, Turkey. A Personal Information Form, the Premenstrual Syndrome Scale (PMSS) and the State-Trait Anger Scale (STAS) were used to collect data. Results: The PMS prevalence was 48.75%. There was a statistically significant difference between the groups in terms of constant anger, anger-in, anger-out and anger control subscales (p <0.001). The average scores of women with PMS for constant anger anger-in and anger-out was significantly higher. The anger control scores were at a significantly lower level. Conclusion: Women with PMS had higher anger and lower anger control levels. It should be advisable to recommend anger control management and provide social support so these women can cope with the symptoms. The result of our study emphasizes the importance of careful assessment of anger in women with premenstrual symptoms. How to cite this:Saglam HY, Basar F. The relationship between premenstrual syndrome and anger. Pak J Med Sci. 2019;35(2):---------.  doi: https://doi.org/10.12669/pjms.35.2.232 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Sexual Dysfunction and Marital Relationship in Women With Schizophrenia in Comparison with Caregivers: A Hospital-based Study

2020 ◽  
Vol 2 (1) ◽  
pp. 87-92
Author(s):  
Suvarna Jyothi Kantipudi ◽  
Navina Suresh ◽  
Poornima Ayyadurai ◽  
Sathianathan Ramanathan
Keyword(s):  
Sexual Dysfunction ◽  
Sexual Function ◽  
Sexual Functioning ◽  
Cross Sectional Study ◽  
Women Caregivers ◽  
Cross Sectional ◽  
Significant Difference ◽  
Relationship Assessment ◽  
The Impact ◽  
The Relationship

Background: Sexual dysfunction is common in females with schizophrenia and is attributed to multiple causes, including individual psychopathology and antipsychotics. Understanding the impact of relationship satisfaction on sexual functioning is not widely studied in schizophrenia. Women caregivers also experience sexual problems and were not studied in the past. Aim: To assess the nature and occurrence of sexual dysfunction in women with schizophrenia in comparison to caregivers of males without severe mental disorder. Methods: A cross-sectional study was conducted. A total of 30 women with schizophrenia were recruited as cases and 26 age-matched controls were recruited from female caregivers. All subjects were assessed using standardized tools such as Female Sexual Function Index (FSFI) and Relationship Assessment Scale along with sociodemographic questionnaire. Results: There was a significant difference in FSFI scores and relationship scores between women with schizophrenia and caregiver control subjects. The relationship quality was better in patients with schizophrenia when compared to caregivers unlike sexual functioning. Conclusion: Sexual functioning in women is a complex phenomenon. A holistic biopsychosocial approach is necessary to understand women’s sexual function.

Development and Psychometric Relationship between Occupational Prestige and Social Health of Nursing Staff: A Cross-Sectional Study

2016 ◽  
Vol 9 (3) ◽  
pp. 251
Author(s):  
Shahin Tohidi ◽  
Maryam Shoorvasi ◽  
Arezoo Shayan ◽  
Hassan Ahmadinia ◽  
Sedigheh Furohari
Keyword(s):  
Cross Sectional Study ◽  
Staff Nurses ◽  
Social Health ◽  
Occupational Prestige ◽  
Cross Sectional ◽  
Significant Difference ◽  
Study Population ◽  
Convenience Sampling ◽  
Promotion Strategies ◽  
The Relationship

<p><strong>BACKGROUND: </strong>One of the features that any profession possesses is that it occupies a social status relative to other professions. The present paper contributes to the discussion on the relationship between nursing occupational prestige and social health.</p><p><strong>METHOD:</strong> This study was a cross-sectional research that was conducted in 2015. The study population consisted of 200 staff nurses working in all hospitals located in Hamedan, Iran. A convenience sampling was employed to select 200 nurses who were asked respond to the 25item Keyes’s Social Health Questionnaire and the16-item Nursing Occupational Prestige Questionnaire. Higher score reflected better social health and occupational prestige. The quantitative analysis of this study was carried out using the Statistical Package for Social Science (SPSS).</p><p><strong>RESULTS:</strong> The results showed that the nurses’ mean score of social health and nursing occupational prestige were respectively 43.88±9.18 and occupational prestige44.83±25.14. Social health was significantly related to occupational prestige in the nurses (r=0.15, P=0.04). 66.5% of the nurses were reported to have average occupational prestige and 75.5% of them were believed to have average social health. There was a statistically significant difference in scores of the occupational prestige among the nursing post (P=0.01), job satisfaction (P&lt;0.001) and job interest (P=0.007).</p><p><strong>CONCLUSION:</strong> Nurses’ social health deserves special attention. Effective social health promotion strategies should be considered for promoting their social health particularly in occupational prestige.</p>

scholarly journals A Survey on Wellness and Its Predictors Amongst Fiji High School Students

2021 ◽  
Vol 9 ◽  
Author(s):  
Latileta Odrovakavula ◽  
Masoud Mohammadnezhad ◽  
Sabiha Khan
Keyword(s):  
High School Students ◽  
Ethnic Groups ◽  
Family Income ◽  
Statistical Tests ◽  
Cross Sectional Study ◽  
School Students ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Significant Difference ◽  
Adolescent Wellness

Background: Adolescent population face a number of health concerns which calls for objective and comprehensive assessment of their wellness during their critical development phase. This study aimed to determine adolescent wellness and its predictors amongst adolescents in secondary schools in Fiji.Methods: This quantitative cross sectional study was conducted in four purposively selected schools in Suva and the greater Suva area, Fiji, between August and September, 2019. Students of Fijian nationality, enrolled into years 11-13 in the selected schools were purposively selected. A structured self-administered questionnaire was used to collect data on four dimensions of wellness including physical, emotional, social, and spiritual. Spearman's Rho correlation was conducted to test for associations. Descriptive and inferential statistical tests were applied to analyze the data by the SPSS software version 25. A p-value &lt; 0.05 was considered significant.Results: A total of 350 students participated in the study. Mean raw scores for wellness dimensions were as follows: physical = 51 (out of 60), psychological = 63 (out of 80), social = 42 (out of 50), and spiritual = 34 (out of 40). For overall wellness, two significant differences were observed: students of Fijian Itaukei descent (193.68 ± 14.2) and participants with a family income of $40,000-50,000 (199.08 ± 12.60) (p = 0.04) had a higher overall wellness score. There were three significant differences observed for psychological wellness dimension; Fijians of Indian descent (64.68 ± 9.30), participants enrolled into year 13 (64.68 ± 9.30) and those with a family income of $40,000-50,000 had higher psychological score. For social wellness, a significant difference was observed: Itaukei participants had higher scores (43.34 ± 4.42) when compared to other ethnic groups (p &lt; 0.05). In terms of spiritual wellness, a significant difference was observed for ethnicity: Itaukei participants had a higher mean score (35.59 ± 4.26) when compared to other ethnic groups (p &lt; 0.05). Strong correlations were observed for all dimensions of wellness.Conclusions: Findings of this study highlighted different factors affecting adolescents' wellness in Fiji. It is recommended that health education and awareness program be carried out for developing adolescent wellness by considering these factors. It is also recommended that parental and family support are provided to adolescents.

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