Probiotics, prebiotics and synbiotics: useful for athletes and active individuals? A systematic review

2020 ◽  
Vol 11 (2) ◽  
pp. 135-149 ◽  
Author(s):  
C.D. Quero Calero ◽  
E. Ortega Rincón ◽  
P. Manonelles Marqueta
Keyword(s):  
Health Effects ◽  
Scientific Evidence ◽  
Experimental Studies ◽  
Nutritional Supplement ◽  
Exclusion Criterion ◽  
Cochrane Library ◽  
Positive Health ◽  
Keywords Probiotics ◽  
Comprehensive Search ◽  
Academic Search

The purpose of this review was to synthesise available knowledge on the main health effects associated with the use of probiotics, prebiotics and/or synbiotics in athletes and active individuals, including their effects on the immune system, oxidative stress, the gastrointestinal and respiratory symptoms, as well as other possible clinical outcomes. A systematic and comprehensive search in electronic databases, including Web of Science (WOS, Scielo), PubMed-MEDLINE, Biblioteca virtual de la Salud (LILACS, IBECS), EBSCO (Academic Search Complete CINAHL; SPORTDiscus) and Cochrane Library, focused on generic articles about probiotics, prebiotics and/or synbiotics and their functionality and effects on human health. The search process was completed using the keywords: ‘probiotics’, ‘prebiotics’, ‘synbiotics’, ‘athletes’ and ‘health’. The only exclusion criterion was experimental studies with animals. A total of 31 studies met the inclusion criteria and were included in the review. The vast majority were experimental studies about probiotics and health effects (n=28), while only a few demonstrated the results of consuming prebiotics and/or synbiotics (n=3) in athletes and active individuals. Although most of the studies reported positive health effects in athletes and active individuals, there is still no substantial scientific evidence to suggest that probiotics, prebiotics and synbiotics play an important role in improving an athlete´s performance. These studies are currently limited in number and quality, hence it is necessary to improve the selection of functional biomarkers and methodological approaches, as well as determining the specific nutritional supplement and exercise doses.

Preface

PEDIATRICS ◽  
1984 ◽  
Vol 74 (4) ◽  
pp. 585-585
Author(s):  
WILLIAM H. FOEGE
Keyword(s):  
Health Effects ◽  
Infant Feeding ◽  
Infant Health ◽  
Task Force ◽  
Scientific Evidence ◽  
Health Department ◽  
The United States ◽  
Positive Health ◽  
Department Of Health ◽  
Infant Feeding Decisions

In November 1981, Dr Edward N. Brandt, Assistant Secretary of Health, Department of Health and Human Services, commissioned the Task Force to examine the scientific evidence regarding infant feeding and infant health in both the United States and developing countries. In addition, the report was to include recent information on trends, infant-feeding practices, and factors associated with infant-feeding decisions. The purpose of the Task Force was to determine those areas that were reasonably well studied and well proven and also to indicate where important deficiencies in knowledge existed. Because of the enormous volume of scientific literature dealing with infant feeding, the Task Force elected to concentrate on the most recent studies. In addition, studies of health effects were reviewed if they primarily addressed clinical outcomes in infants or children as end points. This approach necessarily excluded many of the laboratory studies that provide the theoretical framework under which breast-feeding would be expected to have important positive health effects relative to other forms of infant feeding. The Task Force also realized that because of the nature of clinical and epidemiologic research in this area, few of their conclusions could be based on the gold standard of causal research, namely, the randomized clinical trial. Nevertheless, to avoid arriving at conclusions and to say merely that more research was needed, would not live up to responsibility the Task Force was given. Accordingly, the authors of this report have tried to indicate which observational studies were of sufficient quality and consistency that reasonably firm conclusions could be reached, while indicating methodologic difficulties as they were found.

Pork Consumption in Relation to Body Weight and Composition: A Systematic Review and Meta-analysis

2020 ◽  
Vol 44 (4) ◽  
pp. 513-525
Author(s):  
Ruopeng An ◽  
Jianxiu Liu ◽  
Ruidong Liu
Keyword(s):  
Body Weight ◽  
Lean Mass ◽  
Keyword Search ◽  
Meta Analysis ◽  
Scientific Evidence ◽  
Experimental Studies ◽  
Cochrane Library ◽  
Fat Percentage ◽  
Eligibility Criteria ◽  
Pork Consumption

Objectives: In this study, we systematically synthesized scientific evidence on pork consumption in relation to body weight and composition among adults. Methods: We performed a keyword search using Cochrane Library, PubMed, Web of Science, CINAHL, and Google Scholar. We conducted a meta-analysis to estimate the pooled effect size of pork consumption on body weight and composition. Results: Overall, 12 studies met the eligibility criteria for inclusion in the review. Among the experimental studies without daily total energy intake restrictions, pork intake was associated with a reduction in body weight by 0.86 kg (95% CI = 0.17-1.55) and body fat percentage by 0.77% (95% CI = 0.11%-1.43%); pork intake was not associated with change in lean mass. Among the experimental studies with energy restrictions, pork intake was associated with a reduction in body weight by 5.56 kg (95% CI = 0.55-10.59), lean mass by 1.50 kg (95% CI = 1.39-1.62), and fat mass by 6.60 kg (95% CI = 6.42-6.79). Among the observational studies, pork intake was not associated with overweight/obesity. Conclusions: Findings on pork consumption in relation to body weight/composition differed by study design. Future experimental studies using representative samples are warranted to examine the effect of fresh/lean pork consumption on body weight and composition in the general population and by subgroups.

scholarly journals A systematic review comparing the health effects of dual use of electronic and conventional cigarettes with health effects of exclusive smoking of conventional cigarettes

2022 ◽  
Author(s):  
Charlotta Pisinger ◽  
Sofie Kirstine Bergman Rasmussen
Keyword(s):  
Health Effects ◽  
Large Population ◽  
Experimental Studies ◽  
Tobacco Consumption ◽  
Population Based ◽  
Cochrane Library ◽  
Reverse Causality ◽  
Dual Use ◽  
Term Outcome ◽  
Harmful Substances

Abstract Background: A high prevalence of dual use (DU) of e-cigarettes and conventional cigarettes has been reported across the world. In some countries most users of e-cigarettes are dual users (DUs). We wanted to investigate the health effects of DU and compare with the health effects of exclusive smoking of conventional cigarettes (ESCC). Methods: A systematic search was carried out in PubMed, EMBASE, CINAHL, and Cochrane library. The last search was conducted on April 26, 2021. We included original articles on any topic relevant to health, in all languages. Reviewers independently assessed the main risks of bias without the use of automated tools. We followed the PRISMA guidelines. Both reviewers independently screened and read all publications. Results: Fifty-five publications (52 studies) were included, 12 of the studies were prospective. There was great heterogeneity across studies both in methodology and outcome. Several studies, especially experimental studies with short-term outcome, found higher levels of harmful substances in ESCC than in DUs, however, the two largest population-based studies, with low risk of selection-bias, found higher levels of harmful substances in DUs than in ESCC. Most studies investigating symptoms or risk of disease were large population-based surveys. One study found that DUs reported a significantly better health than ESCC, while fifteen found a higher risk of e.g., pulmonary, cardiovascular or metabolic risk factors/symptoms, self-reported general health or cancer in DUs than in ESCC. The study with the longest follow-up, six years, found that DUs had an adjusted odds ratio of 1.48 (95% confidence interval 0.81–2.70) of a possibly smoking-related disease (confirmed by hospital discharge abstracts) compared with ESCC. Many methodological weaknesses were identified, such as risk of reverse causality. We found a correlation between high tobacco consumption in DUs and findings of negative health outcomes.Conclusion: Due to many methodological weaknesses, it is difficult to draw any strong conclusions, but the results indicate that DU might be as or even more harmful than ESCC. Well-designed longitudinal studies are needed. Before recommending EC for smoking cessation health authorities should consider the high risk of DU and its potential consequences.

scholarly journals Estabilização da coluna vertebral na vítima de trauma – revisão integrativa

2019 ◽  
Vol 19 (1) ◽  
pp. 576-614
Author(s):  
Ana Filipa Gaudêncio Bento ◽  
Patricia Pontífice Sousa
Keyword(s):  
Prehospital Care ◽  
Scientific Evidence ◽  
Penetrating Trauma ◽  
Clinical State ◽  
Cochrane Library ◽  
Behavioral Sciences ◽  
Trauma Victim ◽  
Spinal Stabilization ◽  
Academic Search ◽  
Harmful Effects

Objetivo: Identificar efectos perjudiciales causados por la estabilización de la columna vertebral en la víctima de trauma y situaciones de trauma sin indicación para estabilización de la columna vertebral en el prehospitalario.Método: Se trata de una revisión integrativa de literatura orientada por las cuestiones de investigación: ¿Existe evidencia científica de efectos perjudiciales en las víctimas de trauma, causados por la estabilización de la columna vertebral en el cuidado prehospitalario? y ¿Existen situaciones de trauma sin indicación para estabilización de la columna vertebral?Resultados: Se realizó una investigación booleana en las bases electrónicas Cochrane Library y Pubmed ya través del motor EBSCOhost en las bases de datos CINAHL Plus, MEDLINE, MedicLatina, SPORTDiscus, PsycBras, PsycBOOKS, Psychología y Behavioral Sciences Collection, Academic Search Complete. Se obtuvieron doce artículos y tras la aplicación de los criterios de inclusión y exclusión constituyen la muestra cinco artículos.Conclusiones: Se describen efectos perjudiciales de la estabilización de la columna vertebral en la víctima de trauma relacionados con la gestión de la vía aérea, dolor, malestar y lesiones por presión.Las situaciones de trauma penetrante con circulación inestable y víctimas con lesiones por arma de fuego en la cabeza no carecen de estabilización de la columna vertebral.Se han reunido recomendaciones de apoyo a la decisión prehospitalaria en cuanto a la estabilización de la columna vertebral.Es crucial para la mejora del cuidado prehospitalario, integrar un enfoque individualizado de la víctima que se refiera a su estado clínico y al mecanismo de lesión. Goal: To identify harmful effects caused by the stabilization of the vertebral column in a trauma victim and in trauma situations without indication for stabilization of the spine in the prehospital.Method: It was perform an integrative literature review guided by research questions: is there a scientific evidence of harmful effects on trauma victims caused by spinal stabilization in prehospital care? and are there situations of trauma with no indication for stabilization of the spine?Results: We have performed a Boolean search in the electronic bases Cochrane Library and Pubmed and through the EBSCOhost engine in the databases CINAHL Plus, MEDLINE, MedicLatina, SPORTDiscus, PsycARTICLES, PsycBOOKS, Psychology and Behavioral Sciences Collection, Academic Search Complete. Twelve articles were obtained and after applying the inclusion and exclusion criteria, the sample was five articles.Conclusions: Harmful effects of spinal stabilization on the victim of trauma related to airway management, pain, discomfort and pressure injuries are described.Situations of penetrating trauma with unstable circulation and victims with gunshot injuries to the head do not require stabilization of the spine.Recommendations to support the prehospital decision regarding stabilization of the spine were collected.It is crucial for the improvement of prehospital care to integrate an individualized approach of the victim that refers to its clinical state and mechanism of injury. Objetivo: Identificar efeitos prejudiciais causados pela estabilização da coluna vertebral na vítima de trauma e situações de trauma sem indicação para estabilização da coluna vertebral no pré-hospitalar.Método: Trata-se de uma revisão integrativa de literatura norteada pelas questões de pesquisa: existe evidência científica de efeitos prejudiciais nas vítimas de trauma, causados pela estabilização da coluna vertebral no cuidado pré-hospitalar? e existem situações de trauma sem indicação para estabilização da coluna vertebral?Resultados: Foi realizada pesquisa booleana nas bases eletrónicas Cochrane Library e Pubmed e através do motor EBSCOhost nas bases de dados CINAHL Plus, MEDLINE, MedicLatina, SPORTDiscus, PsycARTICLES, PsycBOOKS, Psychology and Behavioral Sciences Collection, Academic Search Complete. Obtiveram-se doze artigos e após aplicação dos critérios de inclusão e exclusão constitui a amostra cinco artigos.Conclusões: Estão descritos efeitos prejudiciais da estabilização da coluna vertebral na vítima de trauma relacionados com a gestão da via aérea, dor, desconforto e lesões por pressão.Situações de trauma penetrante com circulação instável e vítimas com lesões por arma de fogo na cabeça não carecem de estabilização da coluna vertebral.Foram reunidas recomendações de apoio à decisão pré-hospitalar quanto à estabilização da coluna vertebral.É crucial para a melhoria do cuidado pré-hospitalar, integrar uma abordagem individualizada da vítima que se refira ao seu estado clínico e ao mecanismo de lesão.

scholarly journals Effectiveness of Nutritional Education for Obese Older Adults With Frailty: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 401-401
Author(s):  
Yue-Heng Yin ◽  
Liu Yat Justina
Keyword(s):  
Systematic Review ◽  
Physical Function ◽  
Meta Analysis ◽  
Experimental Studies ◽  
Well Being ◽  
Risk Of Bias ◽  
Cochrane Library ◽  
Nutritional Education ◽  
Hand Search ◽  
Education Interventions

Abstract Obesity has been shown to intensify the decline of physical function and lead to frailty. Nutrition is an important method in managing obesity and frailty, while seldom reviews have ever explored the effects of nutritional education interventions. We conducted a systematic review (PROSPERO: CRD42019142403) to explore the effectiveness of nutritional education interventions in managing body composition and physio-psychosocial parameters related to frailty. Randomized controlled trials and quasi-experimental studies were searched in CINAHL, Cochrane Library, EMBASE, MEDLINE, PsycINFO, PubMed and Scopus from 2001 to 2019. Hand search for the reference lists of included papers was conducted as well. We assessed the quality of included studies by Cochrane risk of bias tool. Meta-analyses and narrative synthesis were used to analyse the data. Two studies with low risk of bias were screened from 180 articles, which involved 177 older people with an average age of 69.69±4.08 years old. The results showed that nutritional education was significantly effective in reducing body weight and fat mass than exercises, and it was beneficial to enhancing physical function and psychosocial well-being. But the effects of nutritional education in increasing muscle strength were not better than exercises. The combined effects of nutritional education and exercises were superior than either exercises or nutritional education interventions solely in preventing the loss of lean mass and bone marrow density, and in improving physical function. Due to limited numbers of relevant studies, the strong evidence of effectiveness of nutritional education interventions on reversing frailty is still lacking.

scholarly journals Potential Benefits of Bovine Colostrum in Pediatric Nutrition and Health

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2551
Author(s):  
Per Torp Sangild ◽  
Caitlin Vonderohe ◽  
Valeria Melendez Hebib ◽  
Douglas G. Burrin
Keyword(s):  
Preterm Birth ◽  
Human Milk ◽  
Animal Studies ◽  
Scientific Evidence ◽  
Growth Failure ◽  
Nutritional Supplement ◽  
Bovine Colostrum ◽  
Infants And Children ◽  
Clinical Complications ◽  
Potential Benefits

Bovine colostrum (BC), the first milk produced from cows after parturition, is increasingly used as a nutritional supplement to promote gut function and health in other species, including humans. The high levels of whey and casein proteins, immunoglobulins (Igs), and other milk bioactives in BC are adapted to meet the needs of newborn calves. However, BC supplementation may improve health outcomes across other species, especially when immune and gut functions are immature in early life. We provide a review of BC composition and its effects in infants and children in health and selected diseases (diarrhea, infection, growth-failure, preterm birth, necrotizing enterocolitis (NEC), short-bowel syndrome, and mucositis). Human trials and animal studies (mainly in piglets) are reviewed to assess the scientific evidence of whether BC is a safe and effective antimicrobial and immunomodulatory nutritional supplement that reduces clinical complications related to preterm birth, infections, and gut disorders. Studies in infants and animals suggest that BC should be supplemented at an optimal age, time, and level to be both safe and effective. Exclusive BC feeding is not recommended for infants because of nutritional imbalances relative to human milk. On the other hand, adverse effects, including allergies and intolerance, appear unlikely when BC is provided as a supplement within normal nutrition guidelines for infants and children. Larger clinical trials in infant populations are needed to provide more evidence of health benefits when patients are supplemented with BC in addition to human milk or formula. Igs and other bioactive factors in BC may work in synergy, making it critical to preserve bioactivity with gentle processing and pasteurization methods. BC has the potential to become a safe and effective nutritional supplement for several pediatric subpopulations.

scholarly journals Nature-Based Rehabilitation for Patients with Long-Standing Stress-Related Mental Disorders: A Qualitative Evidence Synthesis of Patients’ Experiences

2021 ◽  
Vol 18 (13) ◽  
pp. 6897
Author(s):  
Anna Bergenheim ◽  
Gunnar Ahlborg ◽  
Susanne Bernhardsson
Keyword(s):  
Mental Disorders ◽  
Personal Growth ◽  
Full Text ◽  
Evidence Synthesis ◽  
Cochrane Library ◽  
Qualitative Evidence Synthesis ◽  
Perceived Benefits ◽  
Positive Health ◽  
Work Disabilities ◽  
The Cochrane Library

Stress-related mental disorders contribute to work disabilities globally and are a common cause for sick leave. Nature-based rehabilitation (NBR) is a multi-disciplinary approach offered to this patient group on a limited scale. Qualitative studies provide insight into patients’ experiences of NBR, and there is a need to synthesize and assess the certainty of evidence for patient-experienced benefits. The aim was to identify, appraise, and synthesize studies reporting experiences and perceived benefits of participation in multidisciplinary, group-based NBR of adult patients with long-standing stress-related mental disorders. PubMed, Embase, CINAHL, AMED, APA PsycInfo, and the Cochrane Library were searched from inception to December 2020. Reference lists of relevant publications were searched. After title and abstract screening, full-text articles were retrieved and assessed for inclusion. The methodological quality of the included studies was assessed, and certainty of evidence was appraised according to CERQual. The search yielded 362 unique records; 19 full-text publications were assessed for eligibility, and 5 studies were included in the synthesis. The studies were considered relevant regarding context, population, and intervention, and quality was generally assessed as moderate to high. Extracted texts were inductively coded and organized into 16 descriptive themes and 4 broad, analytical themes: Instilling calm and joy; Needs being met; Gaining new insights; and Personal growth. Experiences and perceived benefits of participating in NBR and spending time in a nature environment were described as positive for recovery. Nine of the descriptive themes were based on explicit results from at least four of the five studies. Confidence in the evidence of the qualitative findings ranged from moderate to low. Moderate-to-low certainty evidence from the included studies suggests that patients with long-standing stress-related mental disorders experience positive health effects from participating in NBR.

scholarly journals A systematic review of behavioural and exercise interventions for the prevention and management of chemotherapy-induced peripheral neuropathy symptoms

2021 ◽  
Author(s):  
Mary Anne Lagmay Tanay ◽  
Jo Armes ◽  
Rona Moss-Morris ◽  
Anne Marie Rafferty ◽  
Glenn Robert
Keyword(s):  
Peripheral Neuropathy ◽  
Health Management ◽  
Experimental Studies ◽  
Self Management ◽  
Cochrane Library ◽  
Pharmacological Interventions ◽  
Behavioural Interventions ◽  
Exercise Interventions ◽  
Beneficial Effects ◽  
Recommended Treatment

Abstract Background Chemotherapy-induced peripheral neuropathy (CIPN) can result in functional difficulties. Pharmacological interventions used to prevent CIPN either show low efficacy or lack evidence to support their use and to date, duloxetine remains the only recommended treatment for painful CIPN. Non-pharmacological interventions such as exercise and behavioural interventions for CIPN exist. Purpose The aims were to (1) identify and appraise evidence on existing behavioural and exercise interventions focussed on preventing or managing CIPN symptoms, (2) describe psychological mechanisms of action by which interventions influenced CIPN symptoms, (3) determine the underpinning conceptual models that describe how an intervention may create behaviour change, (4) identify treatment components of each intervention and contextual factors, (5) determine the nature and extent of patient and clinician involvement in developing existing interventions and (6) summarise the relative efficacy or effectiveness of interventions to lessen CIPN symptoms and to improve quality of life, balance and muscle strength. Methods A systematic search of Ovid Medline, Cochrane Library, EMBASE, PsycINFO, Health Management Information Consortium, Global Health and CINAHL was performed to identify articles published between January 2000 to May 2020, followed by OpenGrey search and hand-searching of relevant journals. Studies that explored behavioural and/or exercise interventions designed to prevent or improve symptoms of CIPN in adults who had received or were receiving neurotoxic chemotherapy for any type of cancer, irrespective of when delivered within the cancer pathway were included. Results Nineteen randomised controlled trials and quasi-experimental studies which explored behavioural (n=6) and exercise (n=13) interventions were included. Four studies were rated as methodologically strong, ten were moderate and five were weak. Ten exercise and two behavioural interventions, including those that improved CIPN knowledge and self-management resources and facilitated symptom self-reporting, led to reduced CIPN symptoms during and/or after chemotherapy treatment. Conclusions The extent of potential benefits from the interventions was difficult to judge, due to study limitations. Future interventions should incorporate a clear theoretical framework and involve patients and clinicians in the development process. Implications for Cancer Survivors Our findings show exercise interventions have beneficial effects on CIPN symptoms although higher quality research is warranted. Behavioural interventions that increase patient’s CIPN knowledge, improve self-management capacity and enable timely access to symptom management led to reduced CIPN symptoms.

scholarly journals Sleep positioning systems for children and adults with a neurodisability: A systematic review

2018 ◽  
Vol 82 (1) ◽  
pp. 5-14 ◽  
Author(s):  
Ginny Humphreys ◽  
Tanya King ◽  
Jo Jex ◽  
Morwenna Rogers ◽  
Sharon Blake ◽  
...  
Keyword(s):  
Randomised Controlled Trials ◽  
Cochrane Review ◽  
Management Programme ◽  
The Body ◽  
Cochrane Library ◽  
Positioning Systems ◽  
Comprehensive Search ◽  
Randomised Controlled ◽  
Sleep Positioning

Introduction Sleep positioning systems are often prescribed as part of a 24-hour postural management programme for children and adults with neurodisabilities. In a search for evidence of effectiveness for children with cerebral palsy a recent Cochrane review found two randomised controlled trials. This review aims to appraise a broader set of studies including any neurological diagnosis and users of all ages to inform therapists about the quality of the evidence underlying practice. Method A comprehensive search for all peer-reviewed studies that evaluated the use of sleep positioning systems was conducted in MEDLINE, EMBASE, CINAHL, Cochrane Library databases, BNI, HMIC, PEDro, OTSeeker and clinical trials registries. Disability organisations, manufacturers and colleagues worldwide were also contacted. Titles were screened for relevance by two reviewers. Data were extracted into bespoke quantitative or qualitative forms by one reviewer and checked by a second. Findings were analysed into simple themes. Results A total of 14 studies were eligible for inclusion; all were small and most were of low quality. Inferences of benefits cannot be made from the literature but also no harm was found. Conclusions The body of evidence supporting practice remains small and mostly of low quality. Therapists should remain cautious when presenting the benefits to families.

scholarly journals Cervical Spine Involvement in Mild Traumatic Brain Injury: A Review

2016 ◽  
Vol 2016 ◽  
pp. 1-20 ◽  
Author(s):  
Michael Morin ◽  
Pierre Langevin ◽  
Philippe Fait
Keyword(s):  
Cervical Spine ◽  
Reference Lists ◽  
Keyword Search ◽  
Scientific Evidence ◽  
Signs And Symptoms ◽  
Original Data ◽  
Cochrane Library ◽  
Postconcussion Syndrome ◽  
Health Care Practitioners ◽  
Literature Reviews

Background. There is a lack of scientific evidence in the literature on the involvement of the cervical spine in mTBI; however, its involvement is clinically accepted.Objective. This paper reviews evidence for the involvement of the cervical spine in mTBI symptoms, the mechanisms of injury, and the efficacy of therapy for cervical spine with concussion-related symptoms.Methods. A keyword search was conducted on PubMed, ICL, SportDiscus, PEDro, CINAHL, and Cochrane Library databases for articles published since 1990. The reference lists of articles meeting the criteria (original data articles, literature reviews, and clinical guidelines) were also searched in the same databases.Results. 4,854 records were screened and 43 articles were retained. Those articles were used to describe different subjects such as mTBI’s signs and symptoms, mechanisms of injury, and treatments of the cervical spine.Conclusions. The hypothesis of cervical spine involvement in post-mTBI symptoms and in PCS (postconcussion syndrome) is supported by increasing evidence and is widely accepted clinically. For the management and treatment of mTBIs, few articles were available in the literature, and relevant studies showed interesting results about manual therapy and exercises as efficient tools for health care practitioners.

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