BACTERIAL ISOLATES FROM PATIENTS WITH CHRONIC OTITIS MEDIA AND CHANGES IN THEIR ANTIMICROBIAL SUSCEPTIBILITY WITH ASSAY INOCULUM SIZE

Background: Chronic suppurative otitis media (CSOM) is one of the common diseases of the middle ear especially in developing countries. Early and effective treatment based on the knowledge of causative micro-organisms and their antimicrobial sensitivity pattern ensures prompt clinical recovery and possible complications may be avoided. Objectives: This study was done to determine the pattern of bacterial isolates and to detect their antibiogram. Methods: A total of 103 patients clinically diagnosed of CSOM were enrolled in the study and the samples were obtained from each patient using sterile cotton swabs and cultured for bacterial isolates. Antimicrobial susceptibility test of the isolates were performed using Kirby- Bauer disc diffusion method. Results: Among the cases females were more affected than males. Out of the 103 cases, bacteriological investigation revealed that Pseudomonas aeruginosa 42 (44.68%) and Staphylococcus aureus 31(32.97%) were the predominant bacteria. Ciprofloxacin and Ceftazidime revealed high level of sensitivity whereas high resistance rates were observed for Amoxycillin, Gentamicin and Cephalexin. Conclusion: The study concluded that an appropriate knowledge of the etiological agents and antibacterial susceptibility of microorganisms would contribute to a rational use of antibiotics, success of treatment and reduce the complications of CSOM. Bangladesh J Otorhinolaryngol; October 2016; 22(2): 90-95.

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Bacteriology and antibiotic sensitivity pattern of ear discharge in patients with chronic otitis media; A cross sectional study conducted in tertiary care hospital of Peshawar.

The Professional Medical Journal ◽

10.29309/tpmj/2021.28.05.6098 ◽

2021 ◽

Vol 28 (05) ◽

pp. 671-676

Author(s):

Mubassir Ullah ◽

Muhammad Saleh Faisal ◽

Ali Zaki ◽

Azam Khan ◽

Mamoor Khan ◽

...

Keyword(s):

Otitis Media ◽

Proteus Mirabilis ◽

Chronic Otitis Media ◽

Antibiotic Sensitivity ◽

Cross Sectional Study ◽

Bacterial Isolates ◽

Sectional Study ◽

Cross Sectional ◽

Sensitivity Pattern ◽

Klebsiella Spp

Objective: To determine the frequency of common bacteria and antibiotic sensitivity pattern of ear discharge in patients with chronic otitis media. Study Design: Descriptive Cross Sectional study. Setting: Department of ENT, Northwest General Hospital & Research Centre, Peshawar. Period: February to September 2019. Material & Methods: A total of 196 patients of both gender and age between 13 to 60 years with clinical diagnosis of active chronic otitis media were recruited through consecutive sampling technique. After detailed history and relevant examination, demographic data was recorded and pus specimens were collected from the infected ear on cotton swabs. They were sent to pathology laboratory of hospital for culture of common bacteria (E.coli, Pseudomonas aueroginosa, Proteus mirabilis, Staphylococcus aureus and Klebsiella spp) and their respective antibiotic sensitivity (Co-trimoxazole, Co-Amoxiclav, Ciprofloxacin, Ampicillin, Imipenem, Ceftriaxone and Cefixime). Results: Bacterial isolates were analyzed as 48% Staph aureus, 28% Pseudomonas, 12% Proteus mirabilis, 8% E. coli and 4% Klebsiella spp. Imipenem was sensitive to 94%, ceftriaxone 84%, ciprofloxacin 80%, co-trimoxazole 66%, ampicillin 63%, cefixime 45% and co-amoxiclav against 43% of total bacterial isolates. Conclusion: The common causative organism for active chronic otitis media was Staph aureus followed by Pseudomonas. Imipenem was the most sensitive antibiotic against majority of bacterial isolates followed by ceftriaxone and ciprofloxacin.

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P742 Microbial and antimicrobial susceptibility patterns from patients with chronic otitis media in Ardebil, Iran

International Journal of Antimicrobial Agents ◽

10.1016/s0924-8579(07)70583-6 ◽

2007 ◽

Vol 29 ◽

pp. S183

Author(s):

G.H. Ettehad ◽

S. Refahi ◽

A. Nemmati ◽

A. Pirzadeh ◽

Z. Tazakori

Keyword(s):

Otitis Media ◽

Antimicrobial Susceptibility ◽

Chronic Otitis Media ◽

Susceptibility Patterns

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Antimicrobial susceptibility pattern of bacterial isolates in patients of chronic suppurative otitis media in a tertiary care hospital in India

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20184434 ◽

2018 ◽

Vol 6 (11) ◽

pp. 3705

Author(s):

R. K. Mahajan ◽

Saumya Agarwal ◽

Hishmi Jeram ◽

R. C. Vashishtha

Keyword(s):

Otitis Media ◽

Antimicrobial Susceptibility ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Chronic Suppurative Otitis Media ◽

Care Hospital ◽

Bacterial Isolates ◽

Susceptibility Pattern ◽

Suppurative Otitis Media ◽

Antimicrobial Susceptibility Pattern

Background: Chronic suppurative otitis media (CSOM) is a massive public health problem in developing countries like India, especially among low socio-economic class because of malnutrition, overcrowding, poor hygiene, inadequate health care and recurrent upper respiratory tract infections. CSOM cases unless managed effectively may land into various complications such as persistent otorrhoea, hearing impairment, mastoiditis, labyrinthitis, facial nerve paralysis to more serious intracranial abscesses.Methods: The study was carried out in a tertiary care hospital from January 2017 to December 2017 with an aim to determine the microbiological profile of ear discharge in patients suffering from CSOM and their antimicrobial susceptibility pattern using Kirby Bauer disc diffusion method.Results: Out of 630 samples processed, 407 (64.6%) samples were culture positive. Most common organism isolated was Pseudomonas spp. (43.2%) followed by S. aureus (39.1%). Most of isolates recovered were multidrug resistant.Conclusions: Management of CSOM consists mainly of eradicating infection and closure of tympanic membrane. Periodic monitoring of bacterial isolates and their antibiotic susceptibility pattern is necessary for administering appropriate antibiotics as empirical treatment and also helps in reducing the potentially disabling and fatal complications of CSOM.

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Bacteriological profile and their antibiotic susceptibility pattern in chronic suppurative otitis media (TTD) in a tertiary care hospital

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20192137 ◽

2019 ◽

Vol 5 (4) ◽

pp. 871

Author(s):

Sriram Govindaraj ◽

Jinu Vadakkanethu Iype ◽

Srinivasa V. ◽

Jayendiran S.

Keyword(s):

Otitis Media ◽

Antimicrobial Susceptibility ◽

Antibiotic Susceptibility ◽

Chronic Suppurative Otitis Media ◽

Care Hospital ◽

Bacterial Isolates ◽

Susceptibility Pattern ◽

Suppurative Otitis Media ◽

Antimicrobial Susceptibility Pattern ◽

The Common

Background: Chronic suppurative otitis media (CSOM) is one of the common infective conditions which can cause many complications if not treated properly. Improper use of antibiotic among the common population has led to many drug resistant organisms; therefore it is necessary to study the antimicrobial susceptibility pattern before treating the patient with CSOM. Aim of the study was to identify the bacterial isolates causing CSOM in tubo tympanic disease and to study their antimicrobial susceptibility pattern.Methods: The study was carried out in ENT department in Vinayaka Mission Medical College, Karaikal from July 2018 till December 2018 for six months. 60 patients of CSOM (TTD) with ear discharge attending the ENT Out Patient Department were included in the study. Swabs were collected for culture and sensitivity. Bacterial isolates were identified using standard methods and antibiotic susceptibility testing were done. Results: Pseudomonas species was the most predominant organism, which was seen in 19 patients (38%) followed by Escherichia coli (22%), Staphylococcus aureus (18%), Klebsiella species (10%).Conclusions: A continuous and periodic evaluation of microbiological pattern and their antibiotic sensitivity pattern prevalent in local area, helps in prescribe proper antibiotics for successful treatment of CSOM and thus minimizing its complications and emergence of resistant strains.

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Frequency of Different Bacterial Species and their Antibiogram among Patients with Chronic Otitis Media

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i30b31657 ◽

2021 ◽

pp. 215-220

Author(s):

Mohammad Farooq Bhutta ◽

Ashfaq Hussain ◽

Salman Baig ◽

Asad Ullah ◽

Sarwath Fatimee ◽

...

Keyword(s):

Escherichia Coli ◽

Staphylococcus Aureus ◽

Pseudomonas Aeruginosa ◽

Otitis Media ◽

Antimicrobial Susceptibility ◽

Proteus Mirabilis ◽

Bacterial Species ◽

Chronic Otitis Media ◽

The Other ◽

Suppurative Otitis Media

Aim: To find out the frequency of different bacterial species and their antibiogram among the patients of chronic suppurative otitis media. Study Design: Descriptivecross-sectional. Place and Duration of Study: The study was conducted at the ENT department of Bahawal Victoria hospital between July to December 2020. Methodology: About 50 patients presented with unilateral or bilateral ear discharge and diagnosed as a case of chronic suppurative otitis media were included in the study. The disk diffusion method was used on Mueller-Hinton Agar to detect antimicrobial susceptibility. Multipledrugs were tested for checking antimicrobial susceptibility. The data were analyzed by using Statistical Package for the Social Sciences (SPSS) version 20. Results: The mean age of the study participants was 13.89 ± 12.37 years. The majority of participants were froma younger age group i.e. less than10 years of age with female predominance. It had been found that the majority of cases (51%) were having Staphylococcus aureus infestation followed by Pseudomonas aeruginosa, Escherichia coli and very few with Proteus mirabilis. On the other hand, multiple drugs were tested to find out the antimicrobial susceptibility among the cases of chronic otitis media and the results reported that all the bacterial species were susceptible to Ceftriaxone while the other antibiotics were havinga variable response for different strains of bacteria. Conclusion: Results concluded that the Staphylococcus aureus was the most common organism followed by Pseudomonas aeruginosa, Escherichia coli and very few with Proteus mirabilis. It is important to identify the pathogenic organism and its sensitivity pattern before prescribing any antibiotic.

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