Learning from Paper, Learning from Screens

2013 ◽  
Vol 3 (4) ◽  
pp. 1-27 ◽  
Author(s):  
Kaveri Subrahmanyam ◽  
Minas Michikyan ◽  
Christine Clemmons ◽  
Rogelio Carrillo ◽  
Yalda T. Uhls ◽  
...  
Keyword(s):  
Real World ◽  
Negative Impact ◽  
Experimental Studies ◽  
Or Efficiency ◽  
Computer Screen ◽  
The Real ◽  
Report Quality ◽  
Significant Difference ◽  
Reading Text ◽  
Reading Study

Electronic screens on laptop and tablet computers are being used for reading text, often while multitasking. Two experimental studies with college students explored the effect of medium and opportunities to multitask on reading (Study 1) and report writing (Study 2). In Study 1, participants (N = 120) read an easy and difficult passage on paper, a laptop, or tablet, while either multitasking or not multitasking. Neither multitasking nor medium impacted reading comprehension, but those who multitasked took longer to read both passages, indicating loss of efficiency with multitasking. In Study 2, participants (N = 67) were asked to synthesize source material in multiple texts to write a one-page evidence-based report. Participants read the source texts either on (1) paper, (2) computer screen without Internet or printer access, or (3) computer screen with Internet and printer access (called the “real-world” condition). There were no differences in report quality or efficiency between those whose source materials were paper or computer. However, global report quality was significantly better when participants read source texts on a computer screen without Internet or printer access, compared with when they had Internet and printer access. Active use of paper for note-taking greatly reduced the negative impact of Internet and printer access in the real-world condition. Although participants expressed a preference for accessing information on paper, reading the texts on paper did not make a significant difference in report quality, compared with either of the two computer conditions. Implications for formal and informal learning are discussed.

scholarly journals Comparison of Efficacy in Patients with Metastatic Melanoma Treated with Ipilimumab and Nivolumab Who Did or Did Not Discontinue Treatment Due to Immune-Related Adverse Events: A Real-World Data Study

Cancers ◽  
2021 ◽  
Vol 13 (21) ◽  
pp. 5550
Author(s):  
Morten Fink ◽  
Anders Schwartz Vittrup ◽  
Lars Bastholt ◽  
Inge Marie Svane ◽  
Marco Donia ◽  
...  
Keyword(s):  
Adverse Events ◽  
Metastatic Melanoma ◽  
Real World ◽  
Negative Impact ◽  
Cox Proportional Hazards Model ◽  
Induction Phase ◽  
Discontinue Treatment ◽  
Real World Data ◽  
World Data ◽  
Significant Difference

Immune-related adverse events (irAEs) are very prevalent when treating patients with ipilimumab and nivolumab in combination, and 30–40% of patients discontinue the treatment for this reason. It is of high clinical relevance to investigate the consequences of discontinuing the treatment early since combination therapy with ipilimumab and nivolumab is the first line of treatment for many patients with metastatic melanoma. In this follow-up study, with real-world data from the nationwide DAMMED database, we investigated whether there was a difference in progression-free survival (PFS) and overall survival (OS) for patients who discontinued or did not discontinue treatment within the first four doses of treatment due to irAEs. In total, 448 patients were treated with ipilimumab and nivolumab. Of these, 133 patients discontinued due to irAEs in the induction phase. Using the Cox proportional hazards model, there was no significant difference in PFS when comparing the group that discontinued with the group that did not discontinue. The group that discontinued had a significantly longer OS than the group that received the full length of treatment. Therefore, we conclude that there is no significant negative impact on efficacy for patients who discontinue due to irAEs in the induction phase of combination immunotherapy for metastatic melanoma.

People actually are about as bad as social psychologists say, or worse

2004 ◽  
Vol 27 (3) ◽  
pp. 351-352
Author(s):  
Michael P. Maratsos
Keyword(s):  
Real World ◽  
Experimental Studies ◽  
Good Deal ◽  
The Real ◽  
Self Interest

Experimental studies are not representative of how badly people function. We study people under relatively innocuous conditions, where their self-interests are very low. In the real world, where people's self-interests are much higher, people are much worse a good deal of the time (some illustrations are cited). This is often “adaptive” for the perpetrators, but that doesn't make it “good” behavior. That people function so badly in our experiments, where self-interest is relatively minimal, is what is really terrifying.

scholarly journals Taking a Breath of the Wild: Are geoscientists more effective than non-geoscientists in determining whether game-world landscapes are realistic?

2019 ◽  
Author(s):  
Rolf Hut ◽  
Casper Albers ◽  
Sam Illingworth ◽  
Chris Skinner
Keyword(s):  
Real World ◽  
Great Opportunity ◽  
Van Gogh ◽  
Landscape Features ◽  
The Real ◽  
Game World ◽  
Significant Difference ◽  
Missed Opportunity

Abstract. From the wilderness of Hyrule, the entire continent of Tamriel, to Middle Earth, players of videogames are exposed to wonderous, fantastic, but ultimately fake, landscapes. Given the time people may spend in these worlds, compared to the time they spend being trained in geoscience, we wondered if expert geoscientists would differ from non-geoscientists in whether they judge the landscapes in these games to be realistic. Since games have a great opportunity for tangential learning it would be a missed opportunity if it turns out that features obviously fake to geoscientists are perceived as plausible by non-geoscientists. To satisfy our curiosity and answer this question we conducted a survey where we asked people to judge both photos from real landscapes as well as screenshots from the recent The Legend of Zelda: Breath of the Wild videogame on how likely they thought the features in the picture were to exist in the real world. Since game-world screenshots are easily identified based on their rendered, pixaleted nature, we pre-processed all pictures with an artistic Van Gogh filter that removed the rendered nature, but retained the dominant landscape features. We found that there is a small but significant difference between geoscientists and non-geoscientists with geoscientists being slightly better at judging which pictures are from the real world versus from the game world. While significant the effect is small enough to conclude that fantastical worlds in games can be used for tangential learning on geoscientific subjects.

Prescribing patterns for FOLFIRINOX in the real world.

2018 ◽  
Vol 36 (4_suppl) ◽  
pp. 463-463
Author(s):  
Chad Michael Guenther ◽  
Nizar Bhulani ◽  
Adam Korenke ◽  
Jenny Jing Li ◽  
Leticia Khosama ◽  
...  
Keyword(s):  
Real World ◽  
Prescribing Patterns ◽  
Comprehensive Cancer Center ◽  
Cancer Center ◽  
Bivariate Analysis ◽  
Treatment Delays ◽  
The Real ◽  
Significant Difference ◽  
Ed Visits ◽  
Dose Modifications

463 Background: FOLFIRINOX therapy is associated with improved outcome in patients with gastrointestinal cancers. The regimen can be associated with significant toxicity and empiric dose modifications are often used. We analyzed 1) real-world prescribing patterns of FOLFIRINOX and 2) toxicity of therapy. Methods: Patients undergoing FOLFIRINOX chemotherapy at an academic, NCI-Designated Comprehensive Cancer Center were identified and electronic medical records reviewed. Patients who received at least one dose of FOLFIRINOX were included. Chemotherapy dose, growth factor use and toxicity data was abstracted for the first 8 weeks. ‘Standard FOLFIRNOX’ was defined as the regimen utilized by Conroy et al (NEJM 2011). Any empiric reduction/withholding of drug dose for cycle 1 was classified as ‘modified FOLFIRINOX’. Bivariate analysis was performed on the data. Results: There were 111 patients seen between 5/2011-3/2017 and 94% had pancreatic cancer. Age range was 29-87 years and 52% were female. 59% received ‘modified FOLFIRINOX’ and 20% received empiric growth factors. Line of therapy for standard vs modified respectively was 71.1% vs 45.5% for 1st, 17.8% vs 36.4% for 2nd, and 11.1% vs 18.2% for beyond 2nd (p = 0.03). Patients with ‘modified FOLFIRINOX’ were more likely to have metastatic disease (p = 0.01), have received second line or beyond, and higher ECOG score (p = 0.03). Patients with ‘modified FOLFIRINOX’ had a trend toward fewer treatment-related ED visits or hospitalization vs ‘standard FOLFIRINOX’ (27.2% vs 42.2% p = 0.10) and fewer treatment delays (25.8% vs 42.2% p = 0.07). Conclusions: In the real world setting, a majority of patients on FOLFIRINOX receive empiric dose modifications. Although modified dose did not translate to a significant difference in ED visits, hospitalizations or treatment delays, there was a trend toward fewer events.

State transgression on electronic expression: is it for real?

2017 ◽  
Vol 25 (4) ◽  
pp. 382-401 ◽  
Author(s):  
Argha Ray ◽  
Anjali Kaushik
Keyword(s):  
Human Rights ◽  
National Security ◽  
Real World ◽  
Negative Impact ◽  
Civil Liberties ◽  
General Assembly ◽  
Exploratory Research ◽  
Content Type ◽  
The Real ◽  
Nation States

Purpose Cyberspace is a virtual environment where instantaneous communications are initiated and consumed using computer networks without any natural or artificial boundaries. These communications are not only an exchange of information but also a catharsis on the socio-political environment of the real world. This explosion of electronic expression is often detrimental to the traditional secretive maneuvers of nation states and the exercise of its power. Unable to come to terms with the new reality nation states through legislative action or otherwise attempt to assert its sovereignty in the space that has no political and societal boundaries. This may lead to an encroachment on basic human rights that often have constitutional guarantees in the real world but may be violated in the online milieu. This paper aims to investigate this issue in detail and evaluate whether nation states are using cyber-security as a propaganda tool to transgress on electronic expression. Design/methodology/approach The Website of the UN Office of the High Commissioner for Human Rights states “In December 2013, the United Nations General Assembly adopted resolution 68/167, which expresses deep concern at the negative impact that surveillance and interception of communications may have on human rights”. It further says “The General Assembly called on all States to review their procedures, practices and legislation related to communications surveillance, interception and collection of personal data and emphasized the need for States to ensure the full and effective implementation of their obligations under international human rights law”. With this development, this paper seeks to unravel the role of nation states in using cybersecurity as a propaganda tool by raising the specter of threat to national security and economic wellbeing. The paper is based on exploratory research with data compilation from secondary sources. To collect data, various research papers, books and journals have been referenced and data available in public domain has been accumulated. Findings This paper has tried to unravel state action on cyberspace which often runs counter to the concept of civil liberties. It indicates that in terms of both national security and economic impact, cybercrime represent a very nominal threat vector. Also, cybercrime as compared with other forms of crime is again nominal. Finally, cyber laws and policies of different countries need to be more nuanced such as to allow space for civil liberties. Overall, the propaganda surrounding the malaise of cybercrime seems to be more hype than real. We already have examples of countries who have transgressed into electronic expression in cyber space. Therefore, UN has a valid reason to raise a red flag on this unfolding issue. Originality/value This paper was published at 21st Americas Conference of Information Systems held at Puerto Rico, USA, between August 13-15, 2015 (AMCIS, 2015). The authors of this paper seek review by Editors of the Journal for Republication of original work. The authors have taken cognizance of the Originality Guidelines for Emerald published at this URL www.emeraldgrouppublishing.com/authors/writing/originality.htm

scholarly journals Competition in a Household Energy Conservation Game

2021 ◽  
Vol 13 (21) ◽  
pp. 11991
Author(s):  
Jan Dirk Fijnheer ◽  
Herre van Oostendorp ◽  
Geert-Jan Giezeman ◽  
Remco C. Veltkamp
Keyword(s):  
Energy Consumption ◽  
Energy Conservation ◽  
Attitude Change ◽  
Real World ◽  
Household Energy ◽  
The Real ◽  
Significant Difference ◽  
Saving Behavior ◽  
And Behavior

This paper presents the results of a game study, comparing Powersaver Game including a competition feature versus the same game excluding a competition feature with respect to energy conservation in the household. In a pretest–posttest design, we tested whether change in attitude, knowledge and behavior with respect to energy conservation in the household was different for participants playing Powersaver Game with or without competition. All energy conservation activities that the application provides (e.g., washing clothes at low temperatures) take place in the real world and feedback is based on real-time energy consumption. This so-called reality-enhanced game approach aims to optimize the transfer between the game world and the real world. Household energy consumption changed significantly and positively in the long term due to competition. A significant difference of 8% in energy consumption between both conditions after the intervention was detected. Besides energy conservation, no further differences were detected between conditions. The chain of events, that an increase in knowledge leads to attitude change, which in turn results in behavior change in the long term is confirmed by means of a path analysis. We conclude that Powersaver Game is effective in the transfer of energy conservation knowledge, which leads to energy saving behavior in the long term while competition additionally contributes to more change in behavior.

scholarly journals Studies on the level of neutralizing antibodies produced by inactivated COVID-19 vaccines in the real world

2021 ◽  
Author(s):  
Haiying Zhang ◽  
Yuyuan Jia ◽  
Ying Ji ◽  
Xu Cong ◽  
Yan Liu ◽  
...  
Keyword(s):  
Real World ◽  
Linear Correlation ◽  
Neutralizing Antibodies ◽  
Neutralizing Antibody ◽  
Igg Antibodies ◽  
Serum Samples ◽  
The Real ◽  
Significant Difference ◽  
Positive Rate ◽  
High Linear Correlation

Background Although effective vaccines have been developed against COVID-19, the level of neutralizing antibodies (Nabs) induced after vaccination in the real world is still unknown. To evaluate the level and persistence of NAbs induced by two inactivated COVID-19 vaccines in China. Methods and findings Serum samples were collected from 1,335 people aged 18 and over who were vaccinated with COVID-19 inactivated vaccine in Peking University People's Hospital from January 19 to June 23, 2021, for detection of COVID-19 antibodies. The WHO standard of SARS-CoV-2 NAbs was detected. The coefficients of variation between the detection results and the true values of the NAbs detected by the WHO standard were all lower than the WHO international standard 3% after the dilution of the original and the dilution of the theoretical concentrations of 500 IU/mL, 250 IU/mL, 125 IU/mL, 72.5 IU/mL, 36.25 IU/mL and 18.125 IU/mL. On day 11-70, the positive rate of NAbs against COVID-19 was 82% to 100%; From day 71 to 332, the positive rate of NAbs decreased to 27%. The level of NAbs was significantly higher at 3-8 Weeks than at 0-3 Weeks. There was a high linear correlation between NAbs and IgG antibodies in 1335 vaccinated patients. NAbs levels were decreased in 31 of 38 people (81.6%) at two time points after the second dose of vaccine. There was no significant difference in age between the group with increased and decreased neutralizing antibody levels (x2 =-0.034, P>0.05). The positive rate of NAbs in the two-dose vaccine group (77.3%) was significantly higher than that in the one-dose group (18.1%), with statistical difference (x2=312.590, P<0.001). A total of 206 people who were 11-70 days after receiving the second dose were tested and divided into three groups: 18-40 years old, 41-60 years old and >60 years old. The positive rates of NAbs in three groups (18-40 years old, 41-60 years old and >60 years old) were 95.14%, 78.43% and 81.8%, respectively. The positive rate of NAbs was significantly higher in 18-40 years old than in 41-60 years old (x2=12.547, P <0.01). The titer of NAbs in 18-40 years old group was significantly higher than that in 41-60 years old group (t=-0.222, P <0.01). The positive rate of NAbs in male group (89.32%) was lower than in female (91.26%), but there was no significant difference (x2=0.222, P >0.05). Conclusions The positive rate of NAbs was the highest from 10 to 70 days after the second dose of vaccine, and the positive rate gradually decreased as time went by. There was a high linear correlation between COVID-19 NAbs and IgM/IgG antibodies in vaccinators, suggesting that in cases where NAbs cannot be detected, IgM/IgG antibodies can be detected instead. The level of NAbs produced after vaccination was affected by age, but not by gender. The highest levels of NAbs were produced between shots 21 to 56 days apart, suggesting that 21 to 56 days between shots is suitable for vaccination.

Another route to broadening the scope of social psychology: Ecologically valid research

2004 ◽  
Vol 27 (3) ◽  
pp. 339-340 ◽  
Author(s):  
Samuel D. Gosling
Keyword(s):  
Social Psychology ◽  
Real World ◽  
Social Life ◽  
Laboratory Experiments ◽  
Experimental Studies ◽  
Ecological Studies ◽  
The Real ◽  
Existence Proofs ◽  
Mere Existence

An imbalance is identified in social psychology between controlled experimental studies (which are common) and real-world, ecologically valid studies (which are rare). The preponderance of experimental studies (which provide mere existence proofs and lack realism) helps fuel social psychology's fault-finding focus. Laboratory experiments and ecological studies should be pursued jointly to examine social life in the real world.

The real-world benefit of novel androgen receptor-targeting agents (ARTA) before and after docetaxel in CRPC with bone metastases in Japan: A subanalysis of the PROSTAT-BSI, a prospective observational study before and after approval of novel ARTAs.

2021 ◽  
Vol 39 (6_suppl) ◽  
pp. 43-43
Author(s):  
Atsushi Mizokami ◽  
Rie Fukuda ◽  
Taiki Kamijima ◽  
Kouji Izumi ◽  
Yoshifumi Kadono ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Observational Study ◽  
Hormonal Therapy ◽  
Real World ◽  
Prospective Observational Study ◽  
Favorable Effect ◽  
The Real ◽  
Significant Difference ◽  
Before And After ◽  
Psa Progression

43 Background: ARTAs (enzalutamide and abiraterone) have been approved for relapse of prostate cancer in Japan since 2014. However, the efficacy of ARTAs for overall survival (OS) has not yet been proven in Japanese real-world clinical practice. Bone Scan Index (BSI), amount of bone metastasis in a unit of %, has become available for bone scintigraphy using software of BONENAVI (EXINIbone) in Japan. To confirm the benefit of BSI, we conducted a prospective observational study from 2012 to 2017 on mHSPC and mCRPC prior to docetaxel (presented at ASCO-GU 2020). Then we conducted this subanalysis to investigate the real-world benefit of ARTAs on OS before and after docetaxel. Methods: Patients enrolled as the mHSPC (N = 148) and mCRPC (N = 99) groups in the PROSTAT-BSI registry over a 3-year observation period were analyzed with or without ARTAs or flutamide. Patients were evaluated for PSA progression, BSI progression, and OS during hormonal therapy or chemotherapy. Results: In the mHSPC group, 123 patients were treated with combined androgen blockade (androgen deprivation + 80 mg bicalutamide) as an initial hormonal therapy. Thirty-seven patients were treated with flutamide after PSA progression. Thirty-seven patients were also treated with ARTAs as 2nd or later. Docetaxel was used in 25 patients. There was no significant difference in PSA (median: 265.5 and 248.0 ng/mL; P = 0.877) and BSI (median: 1.28% and 1.68%; P = 0.131) between the ARTA (-) and ARTA (+) groups at the start of hormonal therapy, respectively. Despite a median PSA-PFS disadvantage of 16 months in the ARTA (+) group compared to the ARTA (-) group (median: 8.9 and 25.2 months), OS of both groups were comparable (3-year survival rate: 84.0% and 75.7%; HR [95% CI]:0.556 [0.238-1.299], P = 0.232), respectively, indicating favorable effect of ARTA on OS. Furthermore, OS tended to be more extended in patients who received flutamide prior to ARTAs (N = 21) (HR [95% CI]:0.3175 [0.050-2.026], P = 0.225). In the mCRPC group, 8 patients who used ARTA prior to docetaxel were excluded from this analysis. ARTAs were used to treat relapse after docetaxel in 44 patients. Cabazitaxel was used in 14 patients. There was no significant difference in PSA (median: 16.8 and 26.8 ng/mL; P = 0.240) and BSI (median: 2.43% and 1.48%; P = 0.105) between the ARTA (-) and ARTA (+) groups at the start of docetaxel, respectively. There was no significant difference in PSA-PFS between the ARTA (-) and ARTA (+) groups (median PSA-PFS: 4.3 months and 7.0 months; P = 0.999), but OS was significantly better in the ARTA (+) group in the ARTA (-) group (median OS: 28.9 months vs 21.1 months; HR [95% CI]: 0.484 [0.264-0.888]; P = 0.019). Conclusions: This subanalysis demonstrates the benefit of ARTAs for OS before and after docetaxel in clinical practice.

scholarly journals HIPPERREALITAS, SIMULAKRA PADA RUANG SOSIAL ONLINE

2015 ◽  
Vol 12 (1) ◽  
pp. 21-35
Author(s):  
Mita Rosaliza
Keyword(s):  
Real World ◽  
Social Life ◽  
Social Space ◽  
Negative Impact ◽  
Virtual Community ◽  
Secondary Data ◽  
The Real ◽  
Interview Technique ◽  
Depth Interview ◽  
The Impact

The new social space among others, see from a formation of identities of the players according to the identity of a particular character or their role in the game, the formation. Gamer community is a new virtual community, and there is new informatif network among gamers. Online games have a significant influence on the lives of these players, where the reality is often found in the online space more real to them than the actual reality in everyday life. It was predicted to influence the behaviour of gamers in the real world, so in this research it will also be viewed online gaming influence on behaviour in the real world gamers. This study uses qualitative methods, case studies, in-depth interview technique, observation and secondary data. The data were collected inside and outside of "cyberspace" with involved observatio, where researchers followed individually in the online and offline to get a complate picture of their activities. The results of the research discovers and explains the reasons hiperreality in play, as the impact Hiperreality Addicted and Identity Conflicts in the real world and the world of cyberspace, all based on perceptions and experiences of the players. Thus it can be further identified the negative impact of these technologies in social life.

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