scholarly journals Security Threat Modelling With Bayesian Networks and Sensitivity Analysis for IAAS Virtualization Stack

2021 ◽  
Vol 33 (4) ◽  
pp. 44-69
Author(s):  
Asvija B. ◽  
Eswari R. ◽  
Bijoy M. B.
Keyword(s):  
Sensitivity Analysis ◽  
Bayesian Networks ◽  
Cloud Infrastructure ◽  
Security Threat ◽  
Attack Graph ◽  
Crucial Component ◽  
Threat Modelling ◽  
Definition Of ◽  
Cloud Infrastructures ◽  
Selection Of

Designing security mechanisms for cloud computing infrastructures has assumed importance with the widespread adoption of public clouds. Virtualization security is a crucial component of the overall cloud infrastructure security. In this article, the authors employ the concept of Bayesian networks and attack graphs to carry out sensitivity analysis on the different components involved in virtualization security for infrastructure as a service (IaaS) cloud infrastructures. They evaluate the Bayesian attack graph (BAG) for the IaaS model to reveal the sensitive regions and thus help the administrators to secure the high risk components in the stack. They present a formal definition of the sensitivity analysis and then evaluate using the BAG model for IaaS stack. The model and analysis presented here can also be used by security analysts and designers to make a selection of the security solutions based on the risk profile of vulnerable nodes and the corresponding cost involved in adding a defense against the identified vulnerabilities.

scholarly journals Cloud Infrastructures forIn SilicoDrug Discovery: Economic and Practical Aspects

2013 ◽  
Vol 2013 ◽  
pp. 1-19 ◽  
Author(s):  
Daniele D'Agostino ◽  
Andrea Clematis ◽  
Alfonso Quarati ◽  
Daniele Cesini ◽  
Federica Chiappori ◽  
...  
Keyword(s):  
Cloud Computing ◽  
Ad Hoc ◽  
Bioinformatics Analysis ◽  
General Purpose ◽  
Cloud Infrastructure ◽  
Hybrid Clouds ◽  
Cloud Broker ◽  
Cloud Infrastructures ◽  
Different Levels ◽  
Selection Of

Cloud computing opens new perspectives for small-medium biotechnology laboratories that need to perform bioinformatics analysis in a flexible and effective way. This seems particularly true for hybrid clouds that couple the scalability offered by general-purpose public clouds with the greater control and ad hoc customizations supplied by the private ones. A hybrid cloud broker, acting as an intermediary between users and public providers, can support customers in the selection of the most suitable offers, optionally adding the provisioning of dedicated services with higher levels of quality. This paper analyses some economic and practical aspects of exploiting cloud computing in a real research scenario for thein silicodrug discovery in terms of requirements, costs, and computational load based on the number of expected users. In particular, our work is aimed at supporting both the researchers and the cloud broker delivering an IaaS cloud infrastructure for biotechnology laboratories exposing different levels of nonfunctional requirements.

Selection and Preparation of Specific Tissue Regions For Tem Using Large Epoxy-Embedded Blocks

1973 ◽  
Vol 31 ◽  
pp. 324-325 ◽  
Author(s):  
P. M. Lowrie ◽  
W. S. Tyler
Keyword(s):  
Electron Microscopy ◽  
Anatomical Structures ◽  
Ultrastructural Studies ◽  
Transmission Electron ◽  
Microscopic Evaluation ◽  
Embedded Blocks ◽  
Specific Tissue ◽  
Definition Of ◽  
Areas Of Interest ◽  
Selection Of

The importance of examining stained 1 to 2μ plastic sections by light microscopy has long been recognized, both for increased definition of many histologic features and for selection of specimen samples to be used in ultrastructural studies. Selection of specimens with specific orien ation relative to anatomical structures becomes of critical importance in ultrastructural investigations of organs such as the lung. The uantity of blocks necessary to locate special areas of interest by random sampling is large, however, and the method is lacking in precision. Several methods have been described for selection of specific areas for electron microscopy using light microscopic evaluation of paraffin, epoxy-infiltrated, or epoxy-embedded large blocks from which thick sections were cut. Selected areas from these thick sections were subsequently removed and re-embedded or attached to blank precasted blocks and resectioned for transmission electron microscopy (TEM).

Sensitivity Analysis and Selection of Check Index of Signal Intersection Simulation Model Based on VISSIM

2019 ◽  
Vol 2 (5) ◽  
Author(s):  
Mengda Zhang ◽  
Chenjing Zhou ◽  
Tian-tian Zhang ◽  
Yan Han
Keyword(s):  
Sensitivity Analysis ◽  
Simulation Model ◽  
Optimal Process ◽  
Parameter Calibration ◽  
Index Set ◽  
The Core ◽  
Core Module ◽  
Simulation Parameter ◽  
Simulation Parameters ◽  
Selection Of

Selecting check index quantitatively is the core of the calibration of micro traffic simulation parameters at signal intersection. Five indexes in the node (intersection) module of VISSIM were selected as the check index set. Twelve simulation parameters in the core module were selected as the simulation parameters set. Optimal process of parameter calibration was proposed and model of the intersection of Huangcun west street and Xinghua street in Beijing was built in VISSIM to verify it. The sensitivity analysis between each check index and simulation parameter in their own set was conducted respectively. Sensitive parameter sets of different check indices were obtained and compared. The results show that different indexes have different size of set, and average vehicle delay's is maximum, so it's necessary to select index quantitatively. The results can provide references for scientific selection of the check indexes and improve the study efficiency of parameter calibration.

scholarly journals Promotion of Resilience in Migrants: A Systematic Review of Study and Psychosocial Intervention

2021 ◽  
Author(s):  
Maria Ciaramella ◽  
Nadia Monacelli ◽  
Livia Concetta Eugenia Cocimano
Keyword(s):  
Systematic Review ◽  
Psychosocial Intervention ◽  
Life Experiences ◽  
Psychosocial Interventions ◽  
Migrant Population ◽  
Methodological Choices ◽  
Research Questions ◽  
Definition Of ◽  
Selection Of

AbstractThis systematic review aimed to contribute to a better and more focused understanding of the link between the concept of resilience and psychosocial interventions in the migrant population. The research questions concerned the type of population involved, definition of resilience, methodological choices and which intervention programmes were targeted at migrants. In the 90 articles included, an heterogeneity in defining resilience or not well specified definition resulted. Different migratory experiences were not adequately considered in the selection of participants. Few resilience interventions on migrants were resulted. A lack of procedure’s descriptions that keep in account specific migrants’ life-experiences and efficacy’s measures were highlighted.

scholarly journals Multiple-Criteria Decision-Making and Sensitivity Analysis for Selection of Materials for Knee Implant Femoral Component

Materials ◽  
2021 ◽  
Vol 14 (8) ◽  
pp. 2084
Author(s):  
Raman Kumar ◽  
Rohit Dubey ◽  
Sehijpal Singh ◽  
Sunpreet Singh ◽  
Chander Prakash ◽  
...  
Keyword(s):  
Decision Making ◽  
Sensitivity Analysis ◽  
Femoral Component ◽  
Human Life ◽  
Multiple Criteria Decision Making ◽  
Multiple Criteria ◽  
Biomedical Science ◽  
Human Beings ◽  
Weighted Sum Method ◽  
Selection Of

Total knee replacement (TKR) is a remarkable achievement in biomedical science that enhances human life. However, human beings still suffer from knee-joint-related problems such as aseptic loosening caused by excessive wear between articular surfaces, stress-shielding of the bone by prosthesis, and soft tissue development in the interface of bone and implant due to inappropriate selection of TKR material. The choice of most suitable materials for the femoral component of TKR is a critical decision; therefore, in this research paper, a hybrid multiple-criteria decision-making (MCDM) tactic is applied using the degree of membership (DoM) technique with a varied system, using the weighted sum method (WSM), the weighted product method (WPM), the weighted aggregated sum product assessment method (WASPAS), an evaluation based on distance from average solution (EDAS), and a technique for order of preference by similarity to ideal solution (TOPSIS). The weights of importance are assigned to different criteria by the equal weights method (EWM). Furthermore, sensitivity analysis is conducted to check the solidity of the projected tactic. The weights of importance are varied using the entropy weights technique (EWT) and the standard deviation method (SDM). The projected hybrid MCDM methodology is simple, reliable and valuable for a conflicting decision-making environment.

scholarly journals CONCEPTUAL DESIGN FOR ASSEMBLY IN AEROSPACE INDUSTRY: SENSITIVITY ANALYSIS OF MATHEMATICAL FRAMEWORK AND DESIGN PARAMETERS

2021 ◽  
Vol 1 ◽  
pp. 731-740
Author(s):  
Giovanni Formentini ◽  
Claudio Favi ◽  
Claude Cuiller ◽  
Pierre-Eric Dereux ◽  
Francois Bouissiere ◽  
...  
Keyword(s):  
Sensitivity Analysis ◽  
Conceptual Design ◽  
Design Parameters ◽  
Design For Assembly ◽  
Mathematical Framework ◽  
Commercial Aircraft ◽  
System Architectures ◽  
Complex Engineering ◽  
Aircraft System ◽  
Definition Of

AbstractOne of the most challenging activity in the engineering design process is the definition of a framework (model and parameters) for the characterization of specific processes such as installation and assembly. Aircraft system architectures are complex structures used to understand relation among elements (modules) inside an aircraft and its evaluation is one of the first activity since the conceptual design. The assessment of aircraft architectures, from the assembly perspective, requires parameter identification as well as the definition of the overall analysis framework (i.e., mathematical models, equations).The paper aims at the analysis of a mathematical framework (structure, equations and parameters) developed to assess the fit for assembly performances of aircraft system architectures by the mean of sensitivity analysis (One-Factor-At-Time method). The sensitivity analysis was performed on a complex engineering framework, i.e. the Conceptual Design for Assembly (CDfA) methodology, which is characterized by level, domains and attributes (parameters). A commercial aircraft cabin system was used as a case study to understand the use of different mathematical operators as well as the way to cluster attributes.

scholarly journals Getting to Hope: Perspectives from Patients and Caregivers Living with Chronic Childhood Illness

Children ◽  
2021 ◽  
Vol 8 (6) ◽  
pp. 525
Author(s):  
Emily von Scheven ◽  
Bhupinder K. Nahal ◽  
Rosa Kelekian ◽  
Christina Frenzel ◽  
Victoria Vanderpoel ◽  
...  
Keyword(s):  
Conceptual Model ◽  
Research Question ◽  
Young Patients ◽  
Future Research ◽  
Childhood Onset ◽  
Virtual Focus Groups ◽  
Definition Of ◽  
Selection Of ◽  
Chronic Childhood ◽  
Research Studies

Promoting hope was identified in our prior work as the top priority research question among patients and caregivers with diverse childhood-onset chronic conditions. Here, we aimed to construct a conceptual model to guide future research studies of interventions to improve hope. We conducted eight monthly virtual focus groups and one virtual workshop with patients, caregivers, and researchers to explore key constructs to inform the model. Discussions were facilitated by Patient Co-Investigators. Participants developed a definition of hope and identified promotors and inhibitors that influence the experience of hope. We utilized qualitative methods to analyze findings and organize the promotors and inhibitors of hope within three strata of the socio-ecologic framework: structural, interpersonal, and intrapersonal. Participants identified three types of interventions to promote hope: resources, navigation, and activities to promote social connection. The hope conceptual model can be used to inform the selection of interventions to assess in future research studies aimed at improving hope and the specification of outcome measures to include in hope research studies. Inclusion of the health care system in the model provides direction for identifying strategies for improving the system and places responsibility on the system to do better to promote hope among young patients with chronic illness and their caregivers.

scholarly journals Examining and Fine-tuning the Selection of Glycan Compositions with GlyConnect Compozitor

2020 ◽  
Vol 19 (10) ◽  
pp. 1602-1618 ◽  
Author(s):  
Thibault Robin ◽  
Julien Mariethoz ◽  
Frédérique Lisacek
Keyword(s):  
Search Engine ◽  
Posttranslational Modifications ◽  
Search Engines ◽  
Web Application ◽  
Contextual Information ◽  
Fine Tuning ◽  
Data Sources ◽  
Web Interface ◽  
Definition Of ◽  
Selection Of

A key point in achieving accurate intact glycopeptide identification is the definition of the glycan composition file that is used to match experimental with theoretical masses by a glycoproteomics search engine. At present, these files are mainly built from searching the literature and/or querying data sources focused on posttranslational modifications. Most glycoproteomics search engines include a default composition file that is readily used when processing MS data. We introduce here a glycan composition visualizing and comparative tool associated with the GlyConnect database and called GlyConnect Compozitor. It offers a web interface through which the database can be queried to bring out contextual information relative to a set of glycan compositions. The tool takes advantage of compositions being related to one another through shared monosaccharide counts and outputs interactive graphs summarizing information searched in the database. These results provide a guide for selecting or deselecting compositions in a file in order to reflect the context of a study as closely as possible. They also confirm the consistency of a set of compositions based on the content of the GlyConnect database. As part of the tool collection of the Glycomics@ExPASy initiative, Compozitor is hosted at https://glyconnect.expasy.org/compozitor/ where it can be run as a web application. It is also directly accessible from the GlyConnect database.

General Schema Theory for Genetic Programming with Subtree-Swapping Crossover: Part II

2003 ◽  
Vol 11 (2) ◽  
pp. 169-206 ◽  
Author(s):  
Riccardo Poli ◽  
Nicholas Freitag McPhee
Keyword(s):  
Genetic Programming ◽  
Schema Theory ◽  
Exact Formulation ◽  
Expected Number ◽  
Size Evolution ◽  
General Schema ◽  
Definition Of ◽  
Effective Fitness ◽  
Selection Of ◽  
Exact Definition

This paper is the second part of a two-part paper which introduces a general schema theory for genetic programming (GP) with subtree-swapping crossover (Part I (Poli and McPhee, 2003)). Like other recent GP schema theory results, the theory gives an exact formulation (rather than a lower bound) for the expected number of instances of a schema at the next generation. The theory is based on a Cartesian node reference system, introduced in Part I, and on the notion of a variable-arity hyperschema, introduced here, which generalises previous definitions of a schema. The theory includes two main theorems describing the propagation of GP schemata: a microscopic and a macroscopic schema theorem. The microscopic version is applicable to crossover operators which replace a subtree in one parent with a subtree from the other parent to produce the offspring. Therefore, this theorem is applicable to Koza's GP crossover with and without uniform selection of the crossover points, as well as one-point crossover, size-fair crossover, strongly-typed GP crossover, context-preserving crossover and many others. The macroscopic version is applicable to crossover operators in which the probability of selecting any two crossover points in the parents depends only on the parents' size and shape. In the paper we provide examples, we show how the theory can be specialised to specific crossover operators and we illustrate how it can be used to derive other general results. These include an exact definition of effective fitness and a size-evolution equation for GP with subtree-swapping crossover.

scholarly journals Excise Tax on Alcohol According to Legal Law of Slovak Republic In Terms Of Eu Secondary Law Transposition / Spotrebná Daň Z Liehu V Právnom Poriadku Slovenskej Republiky Z Hľadiska Transpozície Sekundárneho Práva Eú

2015 ◽  
Vol 4 (2) ◽  
pp. 1-6
Author(s):  
Ondrej Beňuš
Keyword(s):  
Food Industry ◽  
Slovak Republic ◽  
Legal Regulation ◽  
Alcoholic Beverages ◽  
Excise Tax ◽  
Excise Taxes ◽  
Stable Component ◽  
Crucial Component ◽  
Selection Of ◽  
The Eu

Abstract Distilling industry is among the traditional sectors of the food industry. It is a significant producers of agricultural primary production and the most stable component of demand in the labour market. Among all the sectors of the food industry, however, it is subject to the greatest extent of the regulation of the business by state, when a crucial component of regulation is the legal regulation of the selection of the excise tax on alcohol. Given the considerable degree of regulation of excise taxes on alcoholic beverages by one of the secondary law of the EU, it is considered appropriate to assess the level of transposition of basic elements of excise tax on alcohol, as defined by literature, into the legal order of the Slovak Republic.

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