Micro-Structural Properties of Zinc Oxide Nano-Particles Synthesized by Bio-Polymeric Templates

2014 ◽  
Vol 906 ◽  
pp. 190-195
Author(s):  
Sujata Mandal ◽  
Dominic Savio ◽  
S.J. Selvaraj ◽  
S. Natarajan ◽  
Asit Baran Mandal
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Nano Particles ◽  
Oxide Nanoparticles ◽  
Electron Microscopic ◽  
Cellulose Fibres ◽  
Wurtzite Phase ◽  
Crystallite Sizes ◽  
Polymeric Templates

Zinc and iron oxide nanoparticles were synthesized using natural bio-polymeric templates viz. cellulose and sodium alginate. Cellulose fibres from different sources viz. filter-and blot-papers, were used as templates for this purpose. The synthesized Zinc oxide nanoparticles were characterized by X-ray diffraction (XRD), fourier transform infra-red spectra (FT-IR), UV-Visible spectrophotomer (UV-Vis) and scanning electron microscopic (SEM) studies. XRD studied confirmed the formation of highly crystalline hexagonal wurtzite phase of ZnO in all the synthesized nanoparticles. The average crystallite sizes of the nanoparticles obtained using different templates, were well below 50 nm. Characteristics of the zinc oxide nanoparticles obtained by template-based techniques were compared with those obtained by co-precipitation technique. Influence of various templates on the characteristics of metal oxide nanoparticles was studied.

scholarly journals Nano ZnO and its Perspective in Anti-Cancer Activities

2017 ◽  
Vol 16 (2) ◽  
pp. 41-52
Author(s):  
N Shobhaa ◽  
N Nandab ◽  
B M Nagabhushana
Keyword(s):  
Zinc Oxide ◽  
Metal Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Nano Particles ◽  
Oxide Nanoparticles ◽  
Zno Nps ◽  
Large Bandwidth ◽  
Anti Cancer ◽  
Potential Applications

Several methods are used to counter the deadly disease cancer. Zinc oxide nanoparticles (ZnO NPs) is one of the metal oxide nanoparticles which had been used in anti-cancer activities due to its large bandwidth and high exciting binding energy and it has potential applications like antibacterial, antifungal, anti-diabetic, anti-inflammatory, wound healing, antioxidant, optic properties and also which holds promise to treat cancer effectively. Studies have shown that Zinc metal oxide nano particles induce cytotoxicity in cancer cells. The mechanism for antitumor could work through apoptosis or the generation of reactive oxygen species or and necrosis, among other possibilities. This review is on some of the most significant antitumor results obtained with zinc oxide nanoparticles depending on their size, surface morphology, methods of preparation and also cytotoxicity result.

Synthesis and Antimicrobial Properties of Zinc Oxide Nanoparticles

2020 ◽  
Vol 20 (10) ◽  
pp. 5977-5996 ◽  
Author(s):  
Saee Gharpure ◽  
Balaprasad Ankamwar
Keyword(s):  
Zinc Oxide ◽  
Zno Nanoparticles ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Physical Contact ◽  
Oxide Nanoparticles ◽  
Synthesis Methods ◽  
Promising Alternative

With increase in incidence of multidrug resistant pathogens, there is a demand to adapt newer approaches in order to combat these diseases as traditional therapy is insufficient for their treatment. Use of nanotechnology provides a promising alternative as antimicrobial agents as against traditional antibiotics. Metal oxides have been exploited for a long times for their antimicrobial properties. Zinc oxide nanoparticles (ZnO NPs) are preferred over other metal oxide nanoparticles because of their bio-compatible nature and excellent antibacterial potentials. The basic mechanism of bactericidal nature of ZnO nanoparticles includes physical contact between ZnO nanoparticles and the bacterial cell wall, generation of reactive oxygen species (ROS) as well as free radicals and release of Zn2+ ions. This review focuses on different synthesis methods of ZnO nanoparticles, various analytical techniques frequently used for testing antibacterial properties, mechanism explaining antibacterial nature of ZnO nanoparticles as well as different factors affecting the antibacterial properties.

The Influences of Aqueous Dispersion Media on the Cytotoxic Effect of Zinc Oxide Nanoparticles

2020 ◽  
Vol 19 (05) ◽  
pp. 2050001
Author(s):  
Kim San Tang ◽  
Jey Sern Tan
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Physical Property ◽  
Aqueous Dispersion ◽  
Particle Dispersion ◽  
Oxide Nanoparticles ◽  
Zno Nps ◽  
Electron Microscopic ◽  
Electron Microscopic Data ◽  
Dispersion Media

Zinc oxide nanoparticles (ZnO-NPs) are widely utilized in many applications due to distinct physical and chemical characteristics. There are growing concerns that abundant use of ZnO-NPs can cause harm to humans and the environment. There is a substantial problem with reproducibility in nanotoxicology research due to the inherent properties of nanoparticles. Dispersion media are used for the preparation of nanoparticles. However, the physical and biological behaviors of ZnO-NPs in aqueous dispersion media are poorly understood. In this study, we investigated the effect of ZnO-NPs on the viability of SH-SY5Y cells. Our results showed that ZnO-NPs diluted from water-dispersed stock solution caused significant cell death at a much lower dose compared to their counterpart diluted from the phosphate-buffered saline (PBS)-dispersed stock solution. Electron microscopic data indicated that ZnO-NPs from the PBS-dispersed stock solution form much larger agglomerates compared to the one from the water-dispersed stock solution. From these data, we can conclude that the types of media used for particle dispersion impact the change in the physical property and cytotoxicity of ZnO-NPs.

scholarly journals Utility of Zinc Oxide Nanoparticles Catalytic Activity in the Electrochemical Determination of Minocycline Hydrochloride

Polymers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 2505
Author(s):  
Amal M. Al-Mohaimeed ◽  
Wedad A. Al-Onazi ◽  
Maha F. El-Tohamy
Keyword(s):  
Zinc Oxide ◽  
Metal Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Electrochemical Determination ◽  
Electrochemical Sensing ◽  
Oxide Nanoparticles ◽  
Regression Equations ◽  
Minocycline Hydrochloride

The current work described the synthesis and characterization of zinc oxide nanoparticles (ZnONPs) and their electrocatalytic activity in the determination of minocycline hydrochloride (MCL). The unique features of metal oxide nanoparticles such as zinc oxide encourage the researchers to investigate the activity of metal oxide nanoparticles as remarkable semiconductor materials active in the electrochemical sensing determination. Herein, the suggested study displayed a comparative determination of minocycline hydrochloride using two conventional and modified ZnONPs-coated wire sensors. The recorded results showed the linear behavior of the enriched ZnONPs sensor over the 1.0 × 10−10–1.0 × 10−2 mol L−1 with respect to 1.0 × 10−6–1.0 × 10−2 mol L−1 for the conventional sensor. The two sensors are working in the pH range of 3–5 with regression equations EmV = (53.2 ± 0.5) log [MCL] + 448.8 and EmV = (58.7 ± 0.2) log [MCL] + 617.76 for conventional and enriched ZnONPs, respectively. The correlation coefficients were 0.9995 and 0.9998 for the previously mentioned sensors, respectively. The validity of the suggested analytical method was evaluated according to the recommended guidelines for methodology and drug analysis. The developed sensors were also used in the quantification of MCL in commercial formulations.

LASER-INDUCED PHOTOLUMINESCENT STUDIES OF Al-DOPED ZINC OXIDE NANOPARTICLES

2010 ◽  
Vol 09 (05) ◽  
pp. 439-445
Author(s):  
DHIRAJ KUMAR ◽  
SUNIL KUMAR ◽  
H. S. BHATTI
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Nitrogen Laser ◽  
X Ray Diffraction ◽  
Electron Microscopic ◽  
Time Resolved ◽  
X Ray ◽  
Aluminum Ions ◽  
Transmission Electron

In this paper, addition of aluminum in zinc oxide is incorporated using low-temperature chemical synthesis route. Aluminum ions help in crystallization of zinc oxide nanoparticles. Characterization of the synthesized nanoparticles of zinc oxide has been done using Transmission electron microscope (TEM), and X-ray diffraction (XRD) analysis, Energy-resolved photoluminescence (PL) spectra and Time-resolved laser-induced photoluminescence (TRPL) at room temperature. Transmission electron microscopic observations and X-Ray diffraction studies indicate highly crystalline nature and particle size of the order of 20 nm in ZnO:Al . Time-resolved laser-induced photoluminescence measurements have been done using pulsed nitrogen laser as an excitation source, operated at wavelength 337.1 nm and having high peak output power of 1 MW. The results show that at higher concentrations of Al doping in host ZnO phosphor, emission intensity is more by several orders of magnitude and lifetime shortening indicates that these nanoparticles are more efficient as compared with lower concentrations of dopant.

scholarly journals Plant-Mediated Zinc Oxide Nanoparticles: Advances in the New Millennium towards Understanding Their Therapeutic Role in Biomedical Applications

Pharmaceutics ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 1662
Author(s):  
Mahadevamurthy Murali ◽  
Nataraj Kalegowda ◽  
Hittanahallikoppal G. Gowtham ◽  
Mohammad Azam Ansari ◽  
Mohammad N. Alomary ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Food Packaging ◽  
Biological Activities ◽  
Drug Loading ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Potential Candidate

Zinc oxide nanoparticles have become one of the most popular metal oxide nanoparticles and recently emerged as a promising potential candidate in the fields of optical, electrical, food packaging, and biomedical applications due to their biocompatibility, low toxicity, and low cost. They have a role in cell apoptosis, as they trigger excessive reactive oxygen species (ROS) formation and release zinc ions (Zn2+) that induce cell death. The zinc oxide nanoparticles synthesized using the plant extracts appear to be simple, safer, sustainable, and more environmentally friendly compared to the physical and chemical routes. These biosynthesized nanoparticles possess strong biological activities and are in use for various biological applications in several industries. Initially, the present review discusses the synthesis and recent advances of zinc oxide nanoparticles from plant sources (such as leaves, stems, bark, roots, rhizomes, fruits, flowers, and seeds) and their biomedical applications (such as antimicrobial, antioxidant, antidiabetic, anticancer, anti-inflammatory, photocatalytic, wound healing, and drug delivery), followed by their mechanisms of action involved in detail. This review also covers the drug delivery application of plant-mediated zinc oxide nanoparticles, focusing on the drug-loading mechanism, stimuli-responsive controlled release, and therapeutic effect. Finally, the future direction of these synthesized zinc oxide nanoparticles’ research and applications are discussed.

scholarly journals Green Synthesis of Zinc Oxide Nanoparticles via Algal Route and its Action on Cancerous Cells and Pathogenic Microbes

2020 ◽  
Vol 3 (1) ◽  
pp. 15-27
Author(s):  
Priyankari Bhattacharya ◽  
Kasturi Chatterjee ◽  
Snehasikta Swarnakar ◽  
Sathi Banerjee
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Melanoma Cells ◽  
Oxide Nanoparticles ◽  
Cellular Viability ◽  
Zno Nps ◽  
B16f10 Cells ◽  
Melanoma B16f10 ◽  
Minimal Damage

Application of metal oxide nanoparticles for treatment of melanoma cells and microbes is being investigated. Zinc oxide nanoparticles (ZnO NPs) deserve special mention where particles cause destruction of melanoma cells with minimal damage to healthy cells. In the present study, pure phase ZnO NPs with particle size of 3.1 nm were synthesized by green route using algal extract. Skin melanoma (B16F10) cells were treated with synthesized ZnO NP and compared with commercial ZnO NPs and analysed for ED50 for cellular viability using 3% (w/v) of the doses. Sensitivity of B16F10 cells towards green synthesized ZnO NP was found to be more than commercial ZnO NPs. Results showed greater reduction in viability of cells exposed to green synthesized ZnO NPs and with increasing dose of the ZnO NPs, percentage viability of cells gradually reduced. 50% decrease in cellular viability (ED50) was obtained for green synthesized ZnO NP at 3% dose while commercial ZnO exhibited ED50 at 6% of doses. The ZnO NP also showed antimicrobial activity against Pseudomonas sp. and Staphylococcus sp. Zone of inhibition (ZOI) exhibited by Pseudomonas aeruginosa and Staphylococcus aureus for disc diffusion and well diffusion assay was around 10-22 mm and 9-12mm respectively.

Preparation of zinc oxide nanoparticles using punica granatum and elettaria cardamomum fruit extract and determining its antibacterial activity against lactobacillus

2020 ◽  
Vol 11 (3) ◽  
pp. 3372-3376
Author(s):  
Shilpa Merlyn Jose ◽  
Hannah.R ◽  
Rajeshkumar S
Keyword(s):  
Zinc Oxide ◽  
Antibacterial Activity ◽  
Metal Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Punica Granatum ◽  
Diffusion Method ◽  
Oxide Nanoparticles ◽  
Fruit Extract ◽  
Elettaria Cardamomum

To determine the antibacterial activity of Zinc oxide nanoparticles synthesised using Punica granatum and Elettaria cardamomum fruit extract against Lactobacillus. Punica granatum and Elettaria cardamomum have been known for their antimicrobial, antioxidant and anti-inflammatory activity. The phytochemicals present in these fruits have experimented for the preparation of various metal and metal oxide nanoparticles. Zinc oxide is a widely used metal oxide nanoparticle known for its good antimicrobial activity against a host of microbes. The current study was conducted to determine its effect against Lactobacillus, a bacteria known for its role in the progression of dental caries. Preparation of fruit extract mediated zinc oxide nanoparticles. Determining the characteristics of the nanoparticles using UV spectroscopy and SEM. Analysing the activity of these nanoparticles against Lactobacillus using agar well diffusion method. The zone of inhibition increased if the concentration of the fruit mediated zinc oxide nanoparticles increased. But it was incomparable to the standards. Hence, further studies need to be conducted using different concentration of Punica granatum and Elettaria cardamomum to determine the optimum fruit extract required for the preparation of the nanoparticles. The resultant nanoparticles can be used as an effective antimicrobial agent against Lactobacillus

scholarly journals ZnO Nano-Particles Production Intensification by Means of a Spinning Disk Reactor

Nanomaterials ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 1321
Author(s):  
Marco Stoller ◽  
Javier Miguel Ochando-Pulido
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Operating Conditions ◽  
Nano Particles ◽  
Precursor Concentration ◽  
Oxide Nanoparticles ◽  
Annual Growth Rate ◽  
Average Dimension ◽  
Industrial Sectors ◽  
Spinning Disk

Zinc Oxide is widely used in many industrial sectors, ranging from photocatalysis, rubber, ceramic, medicine, and pigment, to food and cream additive. The global market is estimated to be USD 3600M yearly, with a global production of 10 Mt. In novel applications, size and shape may sensibly increase the efficiency and a new nano-ZnO market is taking the lead (USD 2000M yearly with a capacity of 1 Mt and an expected Compound Annual Growth Rate of 20%/year). The aim of this work was to investigate the possibility of producing zinc oxide nanoparticles by means of a spinning disk reactor (SDR). A lab-scale spinning disk reactor, previously used to produce other nanomaterials such as hydroxyapatite or titania, has been investigated with the aim of producing needle-shaped zinc oxide nanoparticles. At nanoscale and with this shape, the zinc oxide particles exhibit their greatest photoactivity and active area, both increasing the efficiency of photocatalysis and ultraviolet (UV) absorbance. Working at different operating conditions, such as at different disk rotational velocity, inlet distance from the disk center, initial concentration of Zn precursor and base solution, and inlet reagent solution flowrate, in certain conditions, a unimodal size distribution and an average dimension of approximately 56 nm was obtained. The spinning disk reactor permits a continuous production of nanoparticles with a capacity of 57 kg/d, adopting an initial Zn-precursor concentration of 0.5 M and a total inlet flowrate of 1 L/min. Product size appears to be controllable, and a lower average dimension (47 nm), adopting an initial Zn-precursor concentration of 0.02 M and a total inlet flow-rate of 0.1 L/min, can be obtained, scarifying productivity (0.23 kg/d). Ultimately, the spinning disk reactor qualifies as a process-intensified equipment for targeted zinc oxide nanoparticle production in shape in size.

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