Novel Trends in the Development of Metallic Materials for Medical Implants

2015 ◽  
Vol 647 ◽  
pp. 59-65
Author(s):  
Dalibor Vojtěch ◽  
Jiří Kubásek ◽  
Jaroslav Čapek ◽  
Iva Pospíšilová
Keyword(s):  
Human Population ◽  
Mechanical Performance ◽  
Functional Performance ◽  
Biodegradable Materials ◽  
Metallic Materials ◽  
Medical Implants ◽  
Metallic Biomaterials ◽  
Fixation Devices ◽  
New Directions ◽  
Porous Biomaterials

Metallic biomaterials are currently used in medicine for fabrication of various kinds of implants like joint and bone replacements, dental implants, stents, fixation devices for fractured bones etc. Their advantages over polymeric or ceramic biomaterials are in higher strength, fracture toughness and fatigue life. In addition, metals can be simply processed by established technologies known for centuries. Due to the increasing average age of human population, there are growing requirements for mechanical and functional performance of implants. Therefore, extensive research and development activities are focused on new directions in this area including new surface treatments and alloys with improved biocompatibility and mechanical performance, porous biomaterials, biodegradable metallic materials. Biodegradable materials are explored as alternatives for fabrication of temporary medical implants like stents and fixation devices (screws, plates, nails) for fractured bones. The present paper focuses on new Mg-and Zn-biodegradable alloys. Advantages of these materials are characterized with respect to mechanical performance and corrosion behavior.

Corrosion and Mechanical Behavior of Biodegradable Metallic Biomaterials

2015 ◽  
Vol 227 ◽  
pp. 431-434 ◽  
Author(s):  
Dalibor Vojtěch ◽  
Jiří Kubásek ◽  
Jaroslav Capek ◽  
Alena Michalcova ◽  
Iva Pospíšilová
Keyword(s):  
Mechanical Behavior ◽  
Corrosion Behavior ◽  
Mechanical Performance ◽  
Point Of View ◽  
Medical Implants ◽  
Advantages And Disadvantages ◽  
Metallic Biomaterials ◽  
Biodegradable Metals ◽  
Fixation Devices

Biodegradable alloys are currently studied as prospective biomaterials for temporary medical implants like stents and fixation devices for fractured bones. Among biodegradable metals, only magnesium, zinc and iron meet general requirements of biocompatibility and relative non-toxicity. In the present paper, Mg-, Zn- and Fe-based biodegradable alloys are compared. Advantages and disadvantages of the three kinds of alloying systems are demonstrated regarding the corrosion behavior, mechanical performance and biocompatibility. From the corrosion behavior point of view, Zn- and Fe-based alloys appear as promising alternatives to Mg-based alloys.

Porous Metallic Biomaterials Processing (Review) Part 1: Compaction, Sintering Behavior, Properties and Medical Applications

2017 ◽  
Vol 15 (13) ◽  
pp. 28-40
Author(s):  
Ileana Nicoleta Popescu ◽  
Ruxandra Vidu ◽  
Vasile Bratu
Keyword(s):  
Sintering Behavior ◽  
Medical Applications ◽  
Biomedical Domain ◽  
Metallic Materials ◽  
Medical Implants ◽  
Metallic Biomaterials ◽  
Controlled Porosity ◽  
Complex Forms ◽  
Materials Used ◽  
Porous Biomaterials

AbstractOver the last few decades, researchers has been focused on the study of processing using different methods of new biocompatible and/or biodegradable materials such as permanent or temporary medical implants in reconstructive surgery. The advantages of obtaining biomedical implants by Powder Metallurgy (P/M) techniques are (i) obtaining the near-net-shaped with complex forms, (ii) making materials with controlled porosity or (iii) making mechanically resistant sintered metallic materials used as reinforcing elements for ceramic/polymeric biocompatible materials. In this first part of the 2-part review, the most used and newest metallic biomaterials obtained by P/M methods are presented, along with their compaction and sintering behavior and the properties of the porous biomaterials studied in correlation with the biomedical domain of application.

Biodegradable Metallic Materials for Temporary Medical Implants

2017 ◽  
Vol 891 ◽  
pp. 395-399 ◽  
Author(s):  
Dalibor Vojtěch ◽  
Jiří Kubásek ◽  
Jaroslav Čapek ◽  
Iva Pospíšilová
Keyword(s):  
Blood Vessels ◽  
Corrosion Behavior ◽  
Mechanical Performance ◽  
Metallic Materials ◽  
Medical Implants ◽  
Advantages And Disadvantages ◽  
Fe Alloys

Biodegradable Mg, Zn and Fe alloys are currently studied as prospective biomaterials for temporary medical implants like stents for repairing damaged blood vessels and devices (screws and plates) for fixing fractured bones. In the present paper, novel Mg-, Zn- and Fe-biodegradable alloys are proposed. Advantages and disadvantages of the three kinds of alloys are demonstrated regarding the mechanical performance, in vitro corrosion behavior and biocompatibility.

scholarly journals Beta Titanium Alloys Processed By Laser Powder Bed Fusion: A Review

2021 ◽  
Author(s):  
J. C. Colombo-Pulgarín ◽  
C. A. Biffi ◽  
M. Vedani ◽  
D. Celentano ◽  
A. Sánchez-Egea ◽  
...  
Keyword(s):  
Mechanical Performance ◽  
Functional Performance ◽  
Literature Analysis ◽  
Powder Bed Fusion ◽  
Medical Implants ◽  
Laser Powder Bed Fusion ◽  
Powder Bed ◽  
Beta Titanium ◽  
Structural Applications ◽  
Service Environments

AbstractIn βTi-alloys, some advances and developments have been reached toward optimizing their mechanical performance and their processability. However, the applications of these alloys via laser powder bed fusion (LPBF) are still under investigation. In this work, the processing of βTi-alloys via LPBF and their properties is reviewed with a focus on six selected metallurgical systems which are expected to be top performance materials in applications in the aeronautical and biomedical contexts. These six systems promise a better mechanical and functional performance considering different in-service environments for medical implants and structural applications. After literature analysis, the applicability of βTi-alloys to be processed via LPBF is then discussed considering the relevant fields of applications.

Review of Recent Developments in Surface Nanocrystallization of Metallic Biomaterials

Nanoscale ◽  
2021 ◽  
Author(s):  
Srijan Acharya ◽  
Satyam Suwas ◽  
Kaushik Chatterjee
Keyword(s):  
Human Body ◽  
Surface Characteristics ◽  
Metallic Materials ◽  
Short Term ◽  
Surface Nanocrystallization ◽  
Metallic Biomaterials ◽  
Recent Developments

Metallic materials are widely used to prepare implants for both short-term and long-term use in the human body. The performance of these implants is greatly influenced by their surface characteristics,...

Structure Optimization on FEM Biomechanical Model of Bioabsorable Pure Magnesium Skin Staple

2014 ◽  
Vol 1049-1050 ◽  
pp. 511-514
Author(s):  
Yong Hua Lao ◽  
Yue Shan Huang ◽  
Wei Rong Li ◽  
Ying Jun Wang
Keyword(s):  
Stainless Steel ◽  
Mechanical Strength ◽  
316L Stainless Steel ◽  
Mechanical Performance ◽  
Structure Optimization ◽  
Biomechanical Model ◽  
Pure Magnesium ◽  
Structural Deformation ◽  
Medical Implants ◽  
Surgical Suture

Skin Stapler is an alternative instrument, which makes surgy easily and quickly and owns fine-looking effect without scars after the wound healed, to traditional surgical suture for the wound skin sewing. Magnesium recently is considered to develop medical implants because of its beneficial biocompatibility and bioabsorability. Due its less mechanical strength than traditional 316L stainless steel used in common staple, this paper try to optimize the structure of pure magnesium skin staple by FEM models and simulation as so to assure its biomechanical safty. Using ADINA software, two staples with different pre-bended shoulders and the traditional staple without shoulder are modeling to analyze its stress and plastical strain during structural deformation under load. The results, not only of pure magnesium models but also of 316L stainless steel models, showed that the shoulders optimization on staple structure has important role in its mechanical performance. The research increases the possibility of bioabsorable magnesium material application on medical skin staple.

Influence of conventional and extended CT scale range on quantification of Hounsfield units of medical implants and metallic objects

2018 ◽  
Vol 85 (5) ◽  
pp. 343-350 ◽  
Author(s):  
Zehra Ese ◽  
Marcel Kressmann ◽  
Jakob Kreutner ◽  
Gregor Schaefers ◽  
Daniel Erni ◽  
...  
Keyword(s):  
Artifact Reduction ◽  
Metal Artifact Reduction ◽  
Metallic Materials ◽  
Dose Calculations ◽  
Medical Implants ◽  
Hounsfield Units ◽  
Implantable Medical Devices ◽  
Cardioverter Defibrillator ◽  
Accurate Dose ◽  
Scale Range

Abstract We report on the suitability of two different ranges of Hounsfield units (HU) in computed tomography (CT) for the quantification of metallic components of active implantable medical devices (AIMD). The conventional Hounsfield units (CHU) range, which is traditionally used in radiology, is well suited for tissue but suspected inappropriate for metallic materials. Precise HU values are notably beneficial in radiotherapy (RT) for accurate dose calculations, thus for the safety of patient carrying implants. Some of today’s CT machines offers an extended Hounsfield units (EHU) range. This study presents CT acquisitions of a water phantom containing various metallic discs and an implantable-cardioverter defibrillator (IPG). We show that the comparison of HU values at EHU and CHU ranges clearly reveals the superiority and accuracy of EHU. Some geometrical discrepancies perpendicular to slices are observed. At EHU metal artifact reduction algorithms (MAR) underestimates HU values rendering MAR potentially inappropriate for RT.

scholarly journals The Fundamental Comparison of Zn–2Mg and Mg–4Y–3RE Alloys as a Perspective Biodegradable Materials

Materials ◽  
2019 ◽  
Vol 12 (22) ◽  
pp. 3745 ◽  
Author(s):  
Kubásek ◽  
Dvorský ◽  
Šedý ◽  
Msallamová ◽  
Levorová ◽  
...  
Keyword(s):  
Hot Extrusion ◽  
Visual Observation ◽  
Structure Characterization ◽  
Zinc Alloy ◽  
Biodegradable Materials ◽  
Medical Implants ◽  
Conventional Casting ◽  
Tension And Compression

Biodegradable materials are of interest for temporary medical implants like stents for restoring damaged blood vessels, plates, screws, nails for fixing fractured bones. In the present paper new biodegradable Zn–2Mg alloy prepared by conventional casting and hot extrusion was tested in in vitro and in vivo conditions. Structure characterization and mechanical properties in tension and compression have been evaluated. For in vivo tests, hemispherical implants were placed into a rat cranium. Visual observation of the living animals, an inspection of implant location and computed tomography CT imaging 12 weeks after implantation were performed. Extracted implants were studied using scanning electron microscopy (SEM) on perpendicular cuts through corrosion products. The behaviour of zinc alloy both in in vitro and in vivo conditions was compared with commercially used Mg-based alloy (Mg–4Y–3RE) prepared by conventional casting and hot extrusion. Both compressive and tensile yield strengths of Zn and Mg-based alloys were similar; however, the brittleness of Mg–4Y–3RE was lower. Zn and Mg-based implants have no adverse effects on the behaviour or physical condition of rats. Moreover, gas bubbles and the inflammatory reaction of the living tissue were not detected after the 12-week period.

scholarly journals Failure Analysis of Biometals

Metals ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 662
Author(s):  
Reza Hashemi
Keyword(s):  
Fracture Toughness ◽  
Corrosion Resistance ◽  
Failure Analysis ◽  
High Strength ◽  
Medical Implants ◽  
Load Bearing ◽  
Metallic Biomaterials ◽  
Wear And Corrosion ◽  
Wear And Corrosion Resistance ◽  
Cardiovascular Implants

Metallic biomaterials (biometals) are widely used for the manufacture of medical implants, ranging from load-bearing orthopaedic prostheses to dental and cardiovascular implants, because of their favourable combination of properties including high strength, fracture toughness, biocompatibility, and wear and corrosion resistance [...]

scholarly journals Bone Regeneration in Critical-Sized Bone Defects Treated with Additively Manufactured Porous Metallic Biomaterials: The Effects of Inelastic Mechanical Properties

Materials ◽  
2020 ◽  
Vol 13 (8) ◽  
pp. 1992
Author(s):  
Marianne Koolen ◽  
Saber Amin Yavari ◽  
Karel Lietaert ◽  
Ruben Wauthle ◽  
Amir A. Zadpoor ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Regeneration ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Bulk Material ◽  
Bone Tissue Regeneration ◽  
Bony Tissue ◽  
Metallic Biomaterials ◽  
Cp Ti ◽  
Porous Biomaterials

Additively manufactured (AM) porous metallic biomaterials, in general, and AM porous titanium, in particular, have recently emerged as promising candidates for bone substitution. The porous design of such materials allows for mimicking the elastic mechanical properties of native bone tissue and showed to be effective in improving bone regeneration. It is, however, not clear what role the other mechanical properties of the bulk material such as ductility play in the performance of such biomaterials. In this study, we compared the bone tissue regeneration performance of AM porous biomaterials made from the commonly used titanium alloy Ti6Al4V-ELI with that of commercially pure titanium (CP-Ti). CP-Ti was selected because of its high ductility as compared to Ti6Al4V-ELI. Critical-sized (6 mm diameter) femoral defects in rats were treated with implants made from both Ti6Al4V-ELI and CP-Ti. Bone regeneration was assessed up to 11 weeks using micro-CT scanning. The regenerated bone volume was assessed ex vivo followed by histology and biomechanical testing to assess osseointegration of the implants. The bony defects treated with AM CP-Ti implants generally showed higher volumes of regenerated bone as compared to those treated with AM Ti6Al4V-ELI. The torsional strength of the two titanium groups were similar however, and both considerably lower than those measured for intact bony tissue. These findings show the importance of material type and ductility of the bulk material in the ability for bone tissue regeneration of AM porous biomaterials.

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