Plasma folate studies in HIV-positive patients at the Lagos university teaching hospital, Nigeria

This study evaluated the microalbumin, cystatin C, creatinine and uric acid levels in HIV patients in Nnamdi Azikiwe University Teaching Hospital, Nnewi (NAUTH). A total of one hundred (100) male and female HIV positive and control participants who were aged between 18 and 60 years attending the voluntary counseling and testing unit (VCT) and antiretroviral therapy unit (ART) of NAUTH were randomly recruited for the study and grouped thus: Group A (HIV positive symptomatic participants on long term ART (HPSPLTART) (n= 25); Group B (HIV positive symptomatic participants on short term ART (HPSPSTART) (n= 25); Group C: Asymptomatic HIV positive participants NOT on ART (AHPPNART) (n=25) and Group D: control (n=25).6mls of blood sample and 10mls of freshly voided urine samples were collected from each of the participants for the evaluation of biochemical parameters using standard laboratory methods. Results showed significantly higher BMI and SBP in HPSPSTART than in control (p=0.04; 0.02). SBP was significantly higher in HPSPLTART than in AHPPNART and Control (p=0.00). DBP was significantly higher in HPSPLTART than in HPSPSTART and control respectively (p=0.00). There were significantly higher plasma creatinine and Cys-C levels in both male HIV positives and male HIV positive participants on ART than in both females respectively (p0.00; 0.02). Also, BMI, creatinine, uric acid and Cystatin C levels were significantly higher in male HIV negative participants than in female HIV negative participants (p=0.00; 0.04; 0.02; 0.01). This study has revealed greater risk for renal disease among the HIV participants studied.

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HIV–TB co-infection and associated risk factors among HIV positive patients at Olabisi Onabanjo University Teaching Hospital, Ogun State, South-West Nigeria

HIV & AIDS Review ◽

10.1016/j.hivar.2016.03.004 ◽

2016 ◽

Vol 15 (2) ◽

pp. 69-72

Author(s):

E. Ranti Kolade ◽

O. Glory Atilola ◽

T. Victoria Babalola ◽

O. Isaac Komolafe

Keyword(s):

Risk Factors ◽

Teaching Hospital ◽

University Teaching ◽

Hiv Positive ◽

Ogun State ◽

South West ◽

Associated Risk Factors

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HIV/AIDS Pandemic and Surgical Practice in a Nigerian Teaching Hospital

Tropical Doctor ◽

10.1177/004947550303300414 ◽

2003 ◽

Vol 33 (4) ◽

pp. 228-231 ◽

Cited By ~ 14

Author(s):

Foluso J Owotade ◽

Eyitope O Ogunbodede ◽

Oladayo A Sowande

Keyword(s):

Infection Control ◽

Teaching Hospital ◽

Control Measures ◽

University Teaching ◽

Healthcare Personnel ◽

Hiv Positive ◽

Surgical Practice ◽

Attitudes And Practices ◽

Aids Pandemic ◽

Hiv Aids

The objective of the study was to determine the effects of the HIV/AIDS pandemic on surgical practice in a Nigerian teaching hospital. It involved a questionnaire survey of all the doctors practising in the surgical specialties at Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, Nigeria, in order to obtain their attitudes and practices toward HIV-positive surgical patients. Sixty-five doctors were interviewed, their ages ranged from 26 years to 62 years with a mean age of 35.1 years. The majority (35.4%) were in general surgery or obstetrics and gynaecology (24.6%). Almost half (47.7%) had operated on known HIV-positive patients and the majority were in support of preoperative HIV screening. Almost all (95.4%) were worried about occupational HIV infection – a significant number of consultants would refuse to be screened if their patient were allowed to know the results ( P=0.014). The cross infection control commonly employed included adequate instrument sterilization, presurgical hand washing and the use of gloves and facemasks. The wearing of eye goggles, double gloving, indirect instrument passing and wearing of water impervious gowns were used less frequently. As HIV/AIDS infected individuals are presenting for surgical procedures in the hospital, there is a need to improve the use of universal infection control measures and to educate all categories of healthcare personnel in order to allay the fears and to prevent discrimination that could militate against effective management of HIV/AIDS patients.

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Spectrum Of Chest X-Ray Findings Among Human Immunodeficiency Virus Positive Individuals In A Nigerian Tertiary Hospital

SAARC Journal of Tuberculosis Lung Diseases and HIV/AIDS ◽

10.3126/saarctb.v10i2.9710 ◽

2014 ◽

Vol 10 (2) ◽

pp. 27-34 ◽

Cited By ~ 1

Author(s):

Rachael Adeyanju Akinola ◽

TM Balogun ◽

AA Adeniyi ◽

JAA Onakoya ◽

IO Fabeyibi

Keyword(s):

Immune System ◽

Teaching Hospital ◽

Cd4 Count ◽

University Teaching ◽

Hiv Positive ◽

X Rays ◽

Cd4 Counts ◽

X Ray ◽

Ciency Virus ◽

Chest X Ray

Introduction: Human immunodefi ciency virus infection damages the immune system making those affected more susceptible to opportunistic infections and malignancies which are common in the chest. This study sought to determine the pattern of chest X-ray lesions and the corresponding CD4 counts of HIV positive patients reporting in the antiretroviral clinic of this teaching hospital for the fi rst time. Methodology: Consecutive HIV positive patients that attended the antiretroviral clinic of the Lagos State University Teaching Hospital, (LASUTH) from September 2009 to January 2011 were recruited. Their chest x-rays were assessed for the presence of pulmonary lesions and baseline CD 4 counts were done to assess their degree of immunosuppression. Data were analyzed using the Statistical Package for Social Sciences, version 16.0. Results: There were 211 subjects, 151 females and 60 males with a M:F ratio of 1:2.5 The mean age of participants was 36.5±11.9. Mean baseline CD4 count for the subjects was 279±220.7 cells/mm3. Almost two thirds (64.9%) cases had normal chest x-rays with their mean CD4 count as 277.65±228.54 cells/mm3. The commonest lesions seen in the lungs include pulmonary infi ltrations, 55 (26.1%), cardiomegaly, 24 (11.4%), pulmonary consolidation, 21 (10%) and lymphadenopathy, 14 (6.6%). The commonest radiological diagnosis made were Atypical pneumonitis, 39 (18.5%), pulmonary TB, 13 (6.2%), pneumonia 13 (6.2%) and cardiomegaly13 (6.2%) respectively.Patients with chest findings had lower mean CD4 counts, 239 cells/mm3 when compared to those without, 244 cells/mm3. Conclusion: Pulmonary infiltration was the commonest lesion, while the commonest diagnosis was atypical pneumonitis. Patients with chest x-ray lesions were found to have lower CD4 counts with probable worse destruction of their immune system. SAARC Journal of Tuberculosis, Lung Diseases & HIV/AIDS; 2013; X(2); 27-34 DOI: http://dx.doi.org/10.3126/saarctb.v10i2.9710

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Prevalence of Human Papilloma Virus DNA in HIV Positive Women in Lagos University Teaching Hospital (LUTH) Lagos, Nigeria

British Microbiology Research Journal ◽

10.9734/bmrj/2013/4151 ◽

2013 ◽

Vol 3 (3) ◽

pp. 400-413 ◽

Cited By ~ 6

Author(s):

I. Nweke

Keyword(s):

Human Papilloma Virus ◽

Teaching Hospital ◽

University Teaching ◽

Hiv Positive ◽

Papilloma Virus ◽

Hiv Positive Women

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Determinants of health-related quality of life among human immunodeficiency virus positive (HIV-positive) patients at Ahmadu Bello University teaching hospital, Zaria, Nigeria- 2015

BMC Public Health ◽

10.1186/s12889-020-08659-9 ◽

2020 ◽

Vol 20 (1) ◽

Cited By ~ 1

Author(s):

Bello Abdullahi Suleiman ◽

Mohammed Yahaya ◽

F. A. Olaniyan ◽

A. G. Sule ◽

M. B. Sufiyan

Keyword(s):

Quality Of Life ◽

Human Immunodeficiency Virus ◽

Teaching Hospital ◽

University Teaching ◽

Hiv Positive ◽

Health Related Quality ◽

Immunodeficiency Virus ◽

Related Quality ◽

Health Related

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Escherichia coli Antimicrobial Susceptibility Reduction amongst HIV-Infected Individuals at the University Teaching Hospital, Lusaka, Zambia

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17103355 ◽

2020 ◽

Vol 17 (10) ◽

pp. 3355

Author(s):

Freeman Chabala ◽

Mutinta Madubasi ◽

Mable Mwale Mutengo ◽

Njeleka Banda ◽

Kaunda Yamba ◽

...

Keyword(s):

Escherichia Coli ◽

Teaching Hospital ◽

Antimicrobial Susceptibility ◽

University Teaching ◽

Health Concern ◽

Hiv Positive ◽

E Coli ◽

Stool Samples ◽

The University ◽

Hiv Negative

Increased antimicrobial resistance among Human Immunodeficiency Virus (HIV)-infected individuals to commonly used antibiotics in the treatment of gastroenteritis is a public health concern, especially in resource-limited settings. We set out to compare the antimicrobial susceptibility pattern of Escherichia coli (E. coli) isolates from HIV-infected and HIV-uninfected individuals at a tertiary hospital in Lusaka, Zambia. An analytical cross-sectional study was conducted at the University Teaching Hospital from May 2019 to August 2019. Stool samples were screened, and 79 HIV-infected individuals matched by age and sex with 84 HIV-uninfected individuals that presented with E. coli associated gastroenteritis were studied. Demographics were collected from the Laboratory Information System (LIS) and stool samples were collected in a sterile leak-proof container. Samples were cultured and only those where E. coli was isolated were included in the study and tested for antimicrobial susceptibility by the Kirby–Bauer disk diffusion technique. HIV-positive individuals were 3 times (adjusted odds ratio (AOR) = 3.17; 95% CI (1.51, 6.66); p < 0.001) more likely to be resistant to quinolones compared with their HIV-negative counterparts. Similarly, HIV-positive individuals were almost 4 times (AOR = 3.97, 95% CI (1.37, 11.46); p = 0.011) more likely to have multidrug-resistant E. coli compared with those who were HIV-negative. HIV infection was associated with reduced E. coli susceptibility to commonly used antibiotics, and most cases showed resistance.

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