Quality of life among caregivers of thalassaemic children, attending at Thalassaemia control unit of a rural tertiary care hospital, in a sub-Himalayan district of West Bengal

Thalassaemia is a disease of abnormal development of red blood cells which manifests as anaemia. This chronic disease may cause mental, social, financial burdens on the families, care givers and also on health care system.To assess the quality of life (QOL) of the caregivers of thalassaemic children and to identify the predictors of quality of their physical and mental health.Institution based descriptive cross-sectional study conducted in the Thalassaemia Control Unit (TCU) of North Bengal Medical College (NBMC) from December 2018 to April 2019. Total 136 caregivers of children (≤12 years) with thalassaemia were included by complete enumeration method. Physical and mental health of the caregivers were reported in Short Form-36 (SF-36) Health Survey. Collected data were entered into MS-Excel, analysed with the help of SPSS (Version 22).Mean age of caregivers was 34.3 (SD ± 1.4 years). Most of caregivers were female (89%) and had educational qualification up to Primary school (45.6%). Majority (70.6%) of the caregivers were the mothers of the children. Most of the study participants (60.3%) had favourable Physical health Component Summary (PCS) but 64.7% of the caregivers had unfavourable Mental health component Summary (MCS). Educational status was found to be the predictor for PCS but age and relationship with the child were the predictors for MCS.Counselling, psychotherapy, social support for family members or caregivers of the thalassaemic children and community involvement with their full participation should be emphasized to reduce stigma related to thalassaemia.

Management of menstrual hygiene, practices and perceptions among vulnerable Bharia women in Madhya Pradesh: A pilot survey

India has the highest proportion of adolescents and the highest adolescent pregnancy and childbirth rate in the tribal segment of the population. Very few studies have focused on the use of sanitary pad and quality of health care as menstrual hygiene practices. The data was collected among ‘Bharia’ women who identified as one of the particularly vulnerable tribal groups (PVTGs) in Madhya Pradesh. Towards comparing the use, source, and components of menstrual hygiene practices among adolescents and adult mothers, the sample included adolescent (10-19 years) and adult women 20-49 years of age. The relevant information was collected by trained female investigator with designed questionnaire from the respondents. Findings revealed that only 22.7% women are using sanitary pad during menstruation period in the studied tribe. It was seen the use of this absorbent (sanitary pad) for menstrual hygiene among the adolescents were found significantly higher (37.5%) than that of adult women (14.3%), whereas, the use of old cotton was found significantly higher (78.6%) among adult women. Awareness on menstrual hygiene about 50% adolescents and 64% adult women believed it is a curse of God. About 25% adolescents and 21.4% adult women believed menstruation is a natural process. The tribe has underprivileged menstrual hygiene practices owing to low awareness, illiteracy, and poverty. The special IEC education campaign with suitable strategy can be forced to optimum hygiene practices.

Impact of covid-19 on quality of life in COVID recovered patients: A cross-sectional survey

COVID-19 pandemic has affected India to a great extent. Till date total of 3.30 crore peoples has been cured and discharged and 44.6 lakh are died due to covid -19 in India. COVID-19 has a long-term systemic effect on lungs, liver, spleen, anxiety and depression and persistence of inflammatory response even after getting cured or COVID negative. Which may affect quality of life. So, there is a need to evaluate quality of life in post COVID patients.A cross-sectional study was conducted on the 100 COVID-19 recovered Participants. Participants were selected on the basis of inclusion and exclusion criterion. Basic assessment of symptom history, medical history and hospitalisation was done by investigator. A quality of life was evaluated using short form-36 questionnaire (SF-36). Statistical analysis was done using Microsoft excel-2019.A total of 100 participants 61% were male and 39% were female participants. We found that general health component was greatly affected with 68.50%. Following general health emotional well-being (69.68%), social functioning (68.14), pain (64.38%), limitation due to emotional problems (64.19%), energy/fatigue (63.3%), limitation due to physical health (59.61) and physical functioning (48.27%) were affected.We found that there was mild – moderate affection in quality of life in covid recovered subjects. There was more affection in quality of life in participants with other comorbidities. We also found that there were persistence of breathlessness and fatigue after recovery.

Outcomes in patients of pulmonary tuberculosis treated under RNTCP & follow up after 6 months

Tuberculosis (TB) is, one of the top 10 causes of death worldwide and the leading cause of death from a single infectious agent.This Prospective study was conducted at Santosh medical college Ghaziabad from 1 April 2018 to 30 September 2019. All diagnosed PTB patients above 12yrs were taken. Patients with EPTB, HIV positive, MDR TB, XDR TB were excluded from the study. At the end of study treatment outcome was evaluated.Total of 208 patients diagnosed as tuberculosis were enrolled in the study. 6 patients died during course of study, 10 were treatment failure, 4 were lost to follow-up, 3 transferred out & 1 shifted to private treatment. 184 patients completed treatment successfully. Out of 184, only 152 patients were available for interview at 6 months follow up after completion of treatment. 19 could not be traced, 11 patients refused and 2 died. Out of 152, 110 were asymptomatic, 1 relapsed & rest 41 patients were symptomatic. All symptomatic patients were subjected to Chest X-Ray. Fibrosis was seen on CXR of 30 patients, bronchiectasis was seen in 3 patients, 1 patient had destroyed lung, nothing abnormal detected in 7 patients.Even after successful treatment under RNTCP, these patients need to be followed up as many of them relapse or suffer from sequelae of tuberculosis.

Study of Seroprevalence of SARS CoV2 antibodies in children in a diagnostic centre of Central India-a retrospective study

It is said that children are less affected by SARSCoV2 infection because of their young immune system, so they have relatively milder symptoms as compared to adults. So the true incidence of SARSCoV2 is not known in this age group. Serosurveys in the paediatric age group can give a much better estimate of the incidence of SARSCoV2 infection in asymptomatic and symptomatic childrenThe present study was undertaken to study the seroprevalence of SARSCoV2 antibodies in children below 18 years of age, by measuring the S1RBD domain of spike protein neutralizing IgG antibody levels.This was a retrospective study carried out from August 2020 to August 2021 in a private diagnostic centre of Central India. 539 children of both genders from newborn babies upto 18 years of age were included in the study. US FDA Emergency Use Authorized [EUA], Atellica Solution SARS-CoV-2 IgG assay that detects anti S1-RBD antibodies including neutralizing IgG against SARS-CoV-2 was used for antibody estimation. Antibody level ≥1 was termed reactive or seropositive and below 1 were considered to be non reactive or seroneagtive There were 321 males and 218 females with a male to female ratio of 1.47 :1. 57% male children were seropositive while 61.9% female children showed seropositivity with an overall positivity rate of 58.99%.The findings of our study suggest that chidren below 5 years and adolescents exhibit higher antibody responses as compared to children between 5-10 years of age. The results of our study would be of help in formulating surveillance and vaccination strategies for children and in implementing public safety guidelines.

The pandemic and its impact on occupational health and safety among mechanical engineering industries in India

Workplace health and safety has been of paramount importance for any nation and the stakeholders- authorities, employers and workers – must have reasonable sensitization for the same. During the COVID 19 pandemic, lots of policy formulations and regulations had to incorporate within the industries for the health and welfare of the workers. The “new normal” will take some time for adjustments, challenges and implications to be implemented effectively and consistently. Certain processes in the workplace, especially in the mechanical engineering companies, are likely for high close contact incidences. Special situations pertaining to workers’’ health, like crowded accommodations, travel risks as well common canteens, all need to be reconsidered for providing safer environment to the workers, as far as the current pandemic is concerned. This requires coordinated efforts from all the stakeholders within the mechanical field through subconscious acceptance of the norms of safety and hygiene at all levels.

Effect of trace elements in the immune system of pregnant women attending antenatal clinic in alex ekwueme federal university teaching hospital

Copper, iron, selenium and zinc are important trace elements during pregnancy. They function as antioxidants and play major roles in strengthening the immune system. This study evaluates the importance of these trace elements in the immune system and their concentrations during pregnancy. These trace elements were evaluated using 75 pregnant women attending antenatal clinic in Alex Ekwueme Federal University Teaching Hospital, Abakaliki as Test participants and 75 non-pregnant women were used as control participants. The analysis was done using Atomic Absorption Spectrophotometer. The socio-demographic, Obstetrics and Gynaecological characteristics of the participants were obtained using questionnaire. A cross-sectional comparative study design was adopted for this. The results showed that the mean and standard deviation (M±SD) in mg / l of the test and control of trace elements (copper, iron, selenium and zinc) are; 0.13±0.03 and 0.38±0.03, 0.48±0.07 and 0.82±0.09, 0.86±0.11 and 0.94±0.07, 0.52±0.07 and 0.52±0.05 respectively. Also mean levels of Cu and Fe were significantly decreased in the pregnant women than in control (p=<0.001; 0.002) respectively. Nevertheless, there was no statistically significant differences between selenium and zinc levels in the pregnant women when compared to their controls (p=0.575; 0.982) respectively. Low concentration of iron is suggestive of iron deficiency and this study revealed 65.3% non-compliance to routine iron supplement given during antenatal. Trimester, age and parity appeared not to have any significant effect on the level of these trace elements. Hence, there is need to ensure the intake well-balanced meal to optimize copper levels during pregnancy.

Correlates of COVID-19 vaccination drop-out among health care workers in a tertiary Care hospital of West Bengal

The Government of India launched “COVID-19 vaccination drive” on 16th January, 2021 and health care workers were the first to be prioritised for vaccination. However, the uncertainty regarding safety and efficacy of the vaccine was the major concern amongst them. These led to vaccine hesitancy and ultimately drop out.To estimate the proportion of drop out of COVID-19 vaccination among vaccine-hesitant health care workers (HCWs) of a tertiary care hospital and to find out their perception and other background characteristics responsible for drop out. A facility based descriptive type of observational study, cross-sectional in design was carried out among 329 HCWs of a tertiary care hospital in Kolkata from 16th March- 12thApril, 2021using a pre-designed, pre-tested, structured questionnaire. The study population selected by simple random sampling technique. Data was analysed using Microsoft Excel 2010 and SPSS v25.0 in the form of descriptive statistics and binary logistic regression. About 44.1% of the study population didn’t take the COVID-19 vaccine. Socio-demographic factors like age, gender, religion, education, occupation,perception regarding necessity of vaccination, vaccine efficacy, dose and contraindication, safety in humans and role in future infections were significantly associated with drop out. There was a high proportion of vaccine drop out among health care workers. Different modifiable perceptions with socio-demographic factors had played important roles in COVID-19 vaccination drop out. As the global threat of COVID-19 continues, greater efforts through campaigns that target HCWs are needed to improve the intention of professionals’ vaccine acceptance.

Study of COVID-19 impact on teaching community in border area of India

The COVID-19 pandemic has made the biggest disturbance of education frameworks in mankind's set of experiences, influencing almost 1.6 billion students in excess of 200 nations. Terminations of schools, Colleges and other learning institutions have affected over 94% of the world's understudy populace. This has brought sweeping changes in all parts of our lives. Social separating and prohibitive development strategies have fundamentally upset conventional instructive practices. Returning of schools after unwinding of limitation is one more test with numerous new standard working methodology set up. Inside a limited ability to focus the COVID-19 pandemic, numerous scientists have shared their chips away at educating and learning in an unexpected way. A few schools, universities and colleges have stopped up close and personal lessons. There is a dread of losing 2020 scholastic year or considerably more in the coming future. The need of great importance is to enhance and carry out elective instructive framework and appraisal procedures. The COVID-19 pandemic has furnished us with a chance to make ready for presenting advanced learning. This article expects to give an exhaustive report on the effect of the COVID-19 pandemic on internet educating and learning of different papers and show the way forward.