scholarly journals Prevalence of Pseudomonas aeruginosa in Post-operative Wound Infection in a Referral Hospital in Haryana, India

2010 ◽  
Vol 2 (02) ◽  
pp. 074-077 ◽  
Author(s):  
K Prabhat Ranjan ◽  
Neelima Ranjan ◽  
Satish K Bansal ◽  
D R Arora
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Age Group ◽  
Microbiology Laboratory ◽  
Bacterial Isolates ◽  
Susceptibility Pattern ◽  
Postoperative Wound ◽  
Medical College ◽  
Acinetobacter Spp ◽  
Male Patients ◽  
Klebsiella Spp

ABSTRACT Background: The objective of our study was to determine the prevalence of Pseudomonas aeruginosa in the isolates of postoperative wound and its susceptibility pattern to commonly used antibiotics. Materials and Methods: During a 2-year period, specimens were received as postoperative wound swabs in Microbiology Laboratory, Maharaja Agrasen Medical College, Agroha (Hisar), Haryana, India. Result: Of the 300 bacterial isolates, 89 (29.6%) were P. aeruginosa, followed by Escherichia coli (61, 20.3%), Klebsiella spp. (50, 16.6%), Staphylococcus aureus (43, 14.3%), Proteus spp. (19, 6.3%), Acinetobacter spp. (9, 3.0%), and Citrobacter freundii (2, 0.6%). There was no growth in 27 (9.0%) specimens. Conclusion: P. aeruginosa isolation was higher in male patients and most common in the age group of 21-40 years. The susceptibility pattern showed the organism to be most commonly susceptible to imipenem, followed by meropenem, cefoperazone/sulbactam, ticarcillin/clavulanate, and amikacin.Keywords: Pseudomonas aeruginosa, postoperative wound, prevalence, nosocomial, antibiotic

The Characterization of Antibiotic Resistance of Bacterial Isolates from Intensive Care Unit Patient Samples in a University Affiliated Hospital in Romania

2019 ◽  
Vol 70 (5) ◽  
pp. 1778-1783
Author(s):  
Andreea-Loredana Golli ◽  
Floarea Mimi Nitu ◽  
Maria Balasoiu ◽  
Marina Alina Lungu ◽  
Cristiana Cerasella Dragomirescu ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antibiotic Resistance ◽  
Bacterial Pathogens ◽  
Resistance Rate ◽  
Resistance Pattern ◽  
Bacterial Isolates ◽  
E Coli ◽  
Acinetobacter Spp ◽  
Almost All ◽  
Klebsiella Spp

To determine the resistance pattern of bacterial pathogens involved in infections of the patients aged between 18-64 years, admitted in a ICU from a 1518-bed university-affiliated hospital. A retrospective study of bacterial pathogens was carried out on 351 patients aged between 18-64 years admitted to the ICU, from January to December 2017. In this study there were analysed 469 samples from 351 patients (18-64 years). A total of 566 bacterial isolates were obtained, of which 120 strains of Klebsiella spp. (35.39%%), followed by Nonfermenting Gram negative bacilli, other than Pseudomonas and Acinetobacter (NFB) (75- 22.12%), Acinetobacter spp. (53 - 15.63%), Pseudomonas aeruginosa and Proteus (51 - 15.04%), and Escherichia coli (49 - 14.45%). The most common isolates were from respiratory tract (394 isolates � 69.61%). High rates of MDR were found for Pseudomonas aeruginosa (64.70%), MRSA (62.65%) and Klebsiella spp. (53.33%), while almost all of the isolated NFB strains were MDR (97.33%). There was statistic difference between the drug resistance rate of Klebsiella and E. coli strains to ceftazidime and ceftriaxone (p[0.001), cefuroxime (p[0.01) and to cefepime (p[0.01). The study revealed an alarming pattern of antibiotic resistance in the majority of ICU isolates.

scholarly journals Bacteriological Profile and Antibiogram of Bacterial Isolates from Pus Samples in Tertiary Care Hospital of Kathmandu

2018 ◽  
Vol 4 ◽  
pp. 55-62
Author(s):  
Upendra Pandeya ◽  
Mithileshwor Raut ◽  
Saru Bhattarai ◽  
Padam Raj Bhatt ◽  
Puspa Raj Dahal
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Polymyxin B ◽  
Gram Negative Bacteria ◽  
Bacterial Isolates ◽  
Susceptibility Pattern ◽  
Gram Negative ◽  
Clinical Specimens ◽  
E Coli ◽  
Acinetobacter Spp ◽  
Effective Drugs

Objectives: The main aim of the study was to isolate and identify the bacterial agent and to determine the susceptibility pattern of isolates to different antibiotics.Methods: This retrospective study was conducted from February to October 2015 in microbiology laboratory of All Nepal Hospital Kathmandu, Nepal. The clinical specimens were processed for isolation and identification of bacteria following standard microbiological procedures. Antibiotic susceptibility pattern of isolates were determined according to CLSI guidelines (CLSI 2014)Results: A total of 271 clinical specimens were processed where 164 (60.5%) showed growth positivity. A total 164 bacterial isolates were detected among which 84 (51.22%) were Gram positive 80 (48.78%) were Gram negative bacteria. Thirteen different species of bacteria were isolated. The most prevalent isolate was Staphylococcus aureus 53 (32.30%) followed by E. coli 34 (20.80%), (CoNS) 15 (9.10%), Klebsiella pneumoniae 15 (9.10%), Enterococcus fecalis 12(7.30%), Pseudomonas aeruginosa 10 (6.10%), Acinetobacter spp. 7 (4.30%) Citrobacter spp., Proteus spp., Klebsiella oxytoca were less common. S. aureus was most susceptible to Amikacin. Vancomycin was the most effective drugs for Enterococcus fecalis. Among Gram negative bacteria E. coli was found most sensitive to Polymyxin B (100%) and Imipenem (76.5%) where Pseudomonas aeruginosa was sensitive to, Amikacin, Imipenem (80%). Polymyxin B was the most effective drugs for Klebsiella pneumoniae. Acinetobacter spp. was found highly resistant to different antibiotics.Conclusion: Antibiotic susceptibility evaluation showed Aminoglycosides, Phenicols Polymyxin, and Imipenem was the most effective drugs overall.

scholarly journals Patterns of Antimicrobial Resistance Among Intensive Care Unit Patients of A Private Medical College Hospital in Dhaka

2015 ◽  
Vol 25 (2) ◽  
pp. 47-51 ◽  
Author(s):  
Quazi Tarikul Islam ◽  
Md Mahmudur Rahman Siddiqui ◽  
Farhana Raz ◽  
Mohammad Asrafuzzaman ◽  
Md Robed Amin
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Tracheal Aspirate ◽  
College Hospital ◽  
Icu Patients ◽  
Gram Negative ◽  
Pseudomonas Spp ◽  
Medical College ◽  
Acinetobacter Spp ◽  
Klebsiella Spp

Because of importance of Hospital acquired infections (HAIs), it is critical to conduct surveillance studies to obtain the required data about the regional microorganisms and their susceptibility to antibiotics. This study to investigate antimicrobial resistance pattern among Intensive Care Unit (ICU) patients in a private medical college hospital setup. In a cross sectional study, 100 specimens from patients admitted in the ICU who had signs or symptoms of nosocomial infection were collected from 2012 - 2013. For each patient, samples of blood, urine, tracheal aspirate, sputum, wound swab, pus, and endotracheal tubes were obtained, cultured and analyzed with antibiogram. The most common primary diagnosis were aspiration pneumonia (49%) and UTI (20%) respectively. The most common locations for infection were tracheal aspirate (54%). The most frequent gram negative microorganisms derived from samples were Acinetobacter spp (29%), Klebsiella spp (26%) and Pseudomonas spp (18%). Klebsiella spp, Acinetobacter spp and Pseudomonas spp were most common resistant organisms among all. Klebsiella spp were resistant against Ceftriaxone (84.6%), Ceftazidime (82.6%), Amikacin (46.1%), Gentamicin (66.6%) and Quinolones (65-66.6%) respectively. Acinetobacter spp were resistant against Ceftriaxone (85%), Ceftazidime (88.8%), Cefotaxime (85.7%), Meropenem (79.3%),Amikacin (86.2%), Gentamicin (84.5%) and Quinolons (86.2-89.2%) respectively. Pseudomonas spp were resistant against Ceftriaxone (70.5%), Ceftazidime (66.6%), Amikacin (68.7%), Gentamicin (58.8%), Meropenem (52.9%) and Quinolones (81.2-86.6%) respectively. Meropenem was the most sensitive antibiotic against Klebsiella spp (84.6%) but Cotrimoxazole in case of Acinetobacter spp (60%) respectively. Escherichia coli were mostly isolated from urine, which was sensitive to Amikacin (73.3%) and Meropenem (86.6%) respectively. Gram-negative pathogens obtained from ICU patients in our settings show high resistance to antibiotics. Regular monitoring of the pattern of resistance of common pathogens in the ICUs is essential to up-to-date the use of rational antibiotics regiments.Bangladesh J Medicine Jul 2014; 25 (2) : 47-51

scholarly journals Pola Resistensi Bakteri pada Sputum Pasien PPOK Terhadap Beberapa Antibiotika di Laboratorium Mikrobiologi RSUP Dr.M.Djamil Periode 2010 − 2012

2014 ◽  
Vol 3 (3) ◽  
Author(s):  
Ashima Sonita ◽  
Erly Erly ◽  
Machdawaty Masri
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Streptococcus Pneumoniae ◽  
Proteus Mirabilis ◽  
Staphylococcus Epidermidis ◽  
Empiric Therapy ◽  
Resistance Pattern ◽  
Microbiology Laboratory ◽  
Bacteria Resistance ◽  
Klebsiella Spp

AbstrakPeningkatan resistensi bakteri penyebab PPOK terhadap beberapa antibiotika yang lazim digunakan oleh klinisi dalam pemberian terapi empirik akan menyebabkan berkurangnya keefektifan terhadap terapi PPOK. Hal ini akan berdampak semakin tingginya morbiditas dan mortalitas yang disebabkan oleh PPOK. Penelitian ini bertujuan untuk mengetahui pola resistensi bakteri penyebab PPOK terhadap beberapa antibiotika di Laboratorium Mikrobiologi RSUP.Dr.M.Djamil periode 2010 – 2012. Penelitian ini telah dilaksanakan pada bulan November 2013 sampai dengan Desember 2013 di Laboratotium Mikrobiologi RSUP Dr.M.Djamil Padang. Metode penelitian yang digunakan adalah deskriptif retrospektif. Hasil penelitian mendapatkan bakteri penyebab PPOK adalah Klebsiella spp (42,44%), Streptococcus α hemolyticus (38,37%), Pseudomonas aeruginosa (12,21%), Staphylococcus aureus (4,65%), Proteus mirabilis (1,16%), Staphylococcus epidermidis (0,58%) dan Streptococcus pneumoniae (0,58%). Disimpulkan bahwa bakteri tersering pada sputum pasien PPOK adalah Klebsiella spp. Tingkat resistensi tertinggi adalah Ampicillin, sedangkan tingkat kepekaan tertinggi adalah terhadap Netilmycin.Kata kunci: antibiotika, bakteri, resistensiAbstractIncreased resistance of bacteria that cause COPD to some antibiotics that are commonly used by clicicians in the provision of empiric therapy, it will cause a reduction in the effectiveness of the tratment of COPD. This study aimed to determine the resistance pattern of Bacteria in sputum of patients COPD to some antibiotics in Microbiology Laboratory Dr.M.Djamil Hospital Peroid 2010 – 2012. The research method was a descriptive and retrospective. According to the result, the bacteria that causes COPD is Klebsiella spp (42.44%), Streptococcus α hemolyticus (38.37%), Pseudomonas aeruginosa (12.21%), Staphylococcus aureus (4.65%), Proteus mirabilis (1.16%), Staphylococcus epidermidis (0.58%), and Streptococcus pneumoniae (0.58%). It can be concluded that the bacteria which cause the highest number of COPD is Klebsiella sp. The highest level of resistance is ampicillin while the highest level of sensitivity Is netilmycin.Keywords: antibiotics, bacteria, resistance

scholarly journals Refractive Error Profile in a Tertiary Centre in Western Nepal

2013 ◽  
Vol 2 (2) ◽  
pp. 59-63
Author(s):  
S Taludhar ◽  
S Dhakal
Keyword(s):  
Refractive Error ◽  
Refractive Errors ◽  
Age Group ◽  
Medical College ◽  
Tertiary Centre ◽  
Study Results ◽  
Male Patients ◽  
The Common ◽  
A Prospective Study ◽  
Myopic Astigmatism

INTRODUCTION: Refractive error is one of the causes of avoidable blindness. Myopia, hypermetropia and astigmatism are the common types of refractive error. Not many studies are done to detect pattern of refractive error in Western Nepal. So, the study will determine the prevalence and distribution of refractive errors. MATERIALS AND METHODS: A prospective study of all consecutive patients of age less than 40 years who visited eye department, Gandaki Medical College, between May 2010 and May 2011 was conducted. Visual acuity, naked eye and pin hole examination was done by ophthalmic assistant with cycloplegic refraction when needed. Those who did not turn up for refraction were excluded from the study. RESULTS: A total of 601 patients were seen within the study period. Mean age of male patients was 22.4 years }0.6 (95% CI, 21.2-23.6 years) and mean age of female patients was 24.2 years }0.5 (95% CI, 23.2-25.2 years). Majority of the patients were in age group 11-20 years (39.3%). Myopia was the most common refractive error (43.3%) followed by simple myopic astigmatism (23.8%). Refractive errors were more common in females. CONCLUSIONS: Myopia was the commonest refractive compared to hypermetropia. Refractive error was more common in females than in males. Such studies help to know the picture of refractive errors in community and such reports are helpful in planning programme to prevent avoidable blindness.DOI: http://dx.doi.org/10.3126/ijim.v2i2.8324 Int J Infect Microbiol 2013;2(2):59-63

scholarly journals Clinicopathological study of benign breast diseases a study of 50 cases

2021 ◽  
Vol 8 (5) ◽  
pp. 1462
Author(s):  
Manish Chaudhary ◽  
Purvesh Bhat ◽  
Vedant Wankhede ◽  
Jigar Aagja ◽  
Dhaval Rathva ◽  
...  
Keyword(s):  
Breast Diseases ◽  
Age Group ◽  
Medical College ◽  
Benign Breast Diseases ◽  
Fibrocystic Change ◽  
Wide Range ◽  
Breast Condition ◽  
Malignant Breast ◽  
Male Patients ◽  
The Given

Background: Benign breast diseases are a neglected entity in developing countries despite the fact that they involved in the majority of breast complaints. Benign breast disorders can be defined as any non-malignant breast condition and involved wide range of clinical and pathological disorders. Breast diseases present as swellings. It is a symptom/sign for a different lesion varying from developmental abnormality, inflammatory lesions, epithelial and stromal proliferation to malignancy. Patients were studied on the basis of i.e., clinically, and histopathological ultrasound has done. Our purpose of study is to document various benign Brest diseases to study different mode of presentations of diseases and correlation of clinical and pathological diagnosisMethods: The given study was a prospective and observational study, undertaken in the department of general surgery, govt. medical college Surat, during the study period of March 2018 to September 2019.All the female and male patients with breast related disease were included in this study. Female patients with biopsy proven malignancy were excluded from the study.Results: The study comprised of 50 patients with benign breast diseases; the most common is Fibro adenoma which formed 68% then fibrocystic diseases 20%. With most common age group involved in our study is 21-30 years.Conclusions: Benign breast diseases are more common but ignored entity though it carries majority of complaints and occur mainly in young women less than 30 years of age and were mostly fibro adenoma and fibrocystic change.

scholarly journals Demographic profile of subjects undergoing tympanoplasty in a tertiary care centre of Punjab: analysis of 60 cases

2020 ◽  
Vol 7 (7) ◽  
pp. 2613
Author(s):  
Manish Munjal ◽  
Gopika Talwar ◽  
Shubham Munjal ◽  
Tulika Saggar
Keyword(s):  
Gender Discrimination ◽  
Elective Surgery ◽  
Tertiary Care ◽  
Age Group ◽  
Tertiary Care Centre ◽  
Suppurative Otitis Media ◽  
Medical College ◽  
Minimum Age ◽  
Study Population ◽  
Male Patients

Background: Different tympano meatal vascularised flaps were compared in the tympanoplastic surgery in chronic suppurative otitis media.Methods: 60 cases with diagnosis of chronic suppurative otitis media were selected from ENT OPD of Dayanand Medical College and Hospital Ludhiana. 6 types of tympanomeatal flaps were used and 10 cases of each flap were taken. The study was conducted for the period of 1 year from June 2015 to August 2016.Results: Maximum numbers of patients were in the age group of 31-40 years (26.7%), followed by age group of >50 years (23.3%). Minimum age among these patients was 11 years and maximum 65 years. Mean age was 36.67. Graft failure was in 2 patients, 1 lies under age group 31-40 years and other was in more than 50yrs group. Female patients constituted 56.7% and male patients were 43.3% in our study population. Graft uptake was 93% in females and 100% in males. In our study on 60 patients, 41 (68.3%) patients had a rural and 19 (31.7%) an urban background.Conclusions: Age does not affect the results of tympanoplasty, whatever flap maybe utilised. Awareness in rural population regarding reconstructive ear surgery is there nowadays though there is still gender discrimination, with less number of ladies opting for this elective surgery.

scholarly journals Perfil de sensibilidade a antimicrobianos de bactérias isoladas do trato respiratório baixo de pacientes com pneumonia internados em hospitais brasileiros: resultados do Programa SENTRY, 1997 e 1998

2001 ◽  
Vol 27 (2) ◽  
pp. 59-67 ◽  
Author(s):  
HÉLIO S. SADER ◽  
RODRIGO E. MENDES ◽  
ANA C. GALES ◽  
RONALD N. JONES ◽  
MICHAEL A. PFALLER ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Acinetobacter Spp ◽  
Klebsiella Spp

Introdução: Pneumonia hospitalar é a mais fatal das infecções hospitalares, com taxas de mortalidade de 30 a 60%. Estima-se que 15% de todas as mortes associadas à hospitalização estejam diretamente relacionadas a pneumonias hospitalares. O SENTRY é um estudo de vigilância de resistência a antimicrobianos envolvendo centros médicos em todo o mundo. Objetivo: Avaliar a sensibilidade a antimicrobianos de bactérias isoladas no trato respiratório baixo de pacientes com pneumonia internados em hospitais brasileiros. Material e métodos: Foram avaliadas 525 amostras bacterianas de 11 hospitais brasileiros, como parte do programa SENTRY. Os isolados foram testados por microdiluição em caldo contra um grande número de antimicrobianos. Resultados: As cinco espécies mais freqüentes foram (n/%): Pseudomonas aeruginosa (158/30,1%), Staphylococcus aureus (103/19,6%), Acinetobacter spp. (68/13,0%), Klebsiella spp. (50/9,5%), e Enterobacter spp. (44/8,4%). Essas cinco espécies representam mais de 80% de toda a amostragem. A P. aeruginosa apresentou altas taxas de resistência à maioria dos antimicrobianos testados. As maiores taxas de sensibilidade foram apresentadas por piperacilina/tazobactam (71,5%) e meropenem (69,0%). Os compostos com maior atividade in vitro contra Acinetobacter spp. foram imipenem e meropenem (80,9% de sensibilidade) seguido pela tetraciclina (63,2%). A sensibilidade das amostras de Klebsiella spp. foi muito baixa. MICs > ou = 2mig/mL para ceftriaxona ou ceftazidima, indicando produção de ESBL, foram encontrados em 36,0% das amostras. Os antimicrobianos mais ativos contra Klebsiella spp. foram os carbapenens (100% de sensibilidade) e as quinolonas (92,0% de sensibilidade). Ceftriaxona foi ativa contra somente 56,8% das amostras de Enterobacter spp. (MIC50, 1mig/mL), enquanto a cefepima foi ativa contra 88,6% destes isolados (MIC50, <= 0,12mig/mL). A resistência à oxacilina foi detectada em 43,7% dos isolados de S. aureus. As drogas mais ativas contra essa espécie foram: vancomicina, teicoplanina, quinupristin-dalfopristin e linezolida. Conclusões: Os resultados do presente estudo mostraram alta prevalência de Acinetobacter spp. e altas taxas de resistência entre bacilos gram-negativos quando comparados com resultados de estudos norte-americanos e europeus.

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