scholarly journals Fluoride levels and osteosarcoma

2012 ◽  
Vol 01 (02) ◽  
pp. 76-77 ◽  
Author(s):  
Simmi Kharb ◽  
Ravindra Sandhu ◽  
Zile Singh Kundu
Keyword(s):  
Drinking Water ◽  
Statistical Analysis ◽  
Serum Levels ◽  
Malignant Bone Tumor ◽  
Age Group ◽  
Selective Electrode ◽  
Fluoride Exposure ◽  
Student’S T ◽  
Water Fluoride ◽  
Student’S T Test

Abstract Context: Osteosarcoma is a rare malignant bone tumor, commonly occurring in the age group of 10 to 24 years. Recent reports have indicated that there is a link between fluoride exposure and osteosarcoma. Aims: The present study was planned to analyze serum levels of fluoride in patients of osteosarcoma and fluoride content of their drinking water. Settings and Design: The present study was carried out comparing 10 patients of osteosarcoma and 10 healthy volunteers (who served as controls). Materials and Methods: Serum and drinking water fluoride levels were estimated by ion selective electrode. Statistical analysis used: The data were computed as mean ± SD and Student’s t test was applied. Results: Both, the serum and drinking water fluoride levels, were significant by higher in patients with osteosarcoma as compared to controls (P < 0.05, P < 0.001, respectively). Conclusions: These results suggest a link between fluoride exposure and osteosarcoma.

scholarly journals A Study to Relate Sagittal Condylar Path and Horizontal Incisal Path with Bilateral Balanced Occlusion in Edentulous Subjects

2020 ◽  
Vol 10 (01) ◽  
pp. 31-41
Author(s):  
Krishna Prasad D. ◽  
B. Rajendra Prasad ◽  
Anupama Prasad D.
Keyword(s):  
Statistical Analysis ◽  
T Test ◽  
Blue Color ◽  
Age Group ◽  
Centric Relation ◽  
Pearson Coefficient ◽  
Coefficient Corrélation ◽  
Student’S T ◽  
Artificial Teeth ◽  
Student’S T Test

Abstract Introduction Bilateral balanced occlusion is achieved when there is equilibrium on both sides of the prosthesis, due to the simultaneous contact of the artificial teeth in centric and eccentric occlusion. One of the areas in which research is lacking is the relation between sagittal condylar path (CP) and horizontal incisal path (IP) with optimal balanced occlusion. Materials and Methods Semiadjustable Articulator Artex Arcon AP with Rotofix facebow, 40 µ Bosch articulating paper of red and blue color, protractor, centric and protrusive interocclusal plaster records were used for the study on 50 completely edentulous subjects. Teeth arrangement was done with optimal balanced occlusion, and the numbers of contacts were recorded in centric relation and eccentric positions. Statistical analysis was done by using student’s t test and Karl Pearson coefficient correlation. Results The average sagittal CP was 30.38° in the age group of 40 to 55 years and 32.58° in the age group of 56 to 70 years, and the average horizontal IP was 15.79° in the age group of 40 to 55 years and 16.04° in the age group of 56 to 70 years.Statistically significant results were found between sagittal CP, horizontal IP with bilateral balanced occlusion in the age group of 40–55 years. Conclusion Statistically significant relations were found in balanced occlusion between waxed up denture on articulator, processed denture on articulator and processed denture on articulator after selective grinding. Balanced occlusion is more predictable in a younger group of individuals.

scholarly journals Assessment of 2D:4D in Subjects with Anteroposterior Mandibular Dysplasia

2013 ◽  
Vol 14 (4) ◽  
pp. 582-585 ◽  
Author(s):  
Sridhar Premkumar ◽  
Bhuvaneswari Gurumurthy
Keyword(s):  
Statistical Analysis ◽  
Diagnostic Tool ◽  
Ventral Surface ◽  
Craniofacial Development ◽  
Age Group ◽  
Mandibular Growth ◽  
Mandibular Prognathism ◽  
Testosterone Levels ◽  
Student’S T ◽  
Student’S T Test

ABSTRACT Objectives To compare 2D:4D ratio which is determined by testosterone levels with patients having orthognathic, retrognathic and prognathic mandibles. Materials and methods The study was performed at Chennai, on 320 subjects of which, 60 subjects (32 males and 28 females) had retrognathic mandible; 55 subjects (25 males and 30 females) had prognathic mandible and 205 subjects (98 males and 107 females) had normal mandible. All the subjects had a normal maxilla and were in the age group of 18 to 25 years. 2D:4D ratio was determined using the photocopies of the ventral surface of right hand made with vernier calipers of 0.01 mm accuracy. Statistical analysis was undertaken using Student's t- test, ANOVA test and TukeyHSD test. Results (i) Low 2D:4D is seen in subjects with mandibular prognathism, (ii) Among females, low 2D:4D is seen only in prognathic mandible. Conclusion These findings highlight the fact that testosterone plays an important role in mandibular growth. Thus 2D:4D, a least invasive and reproducible procedure can be used as an early marker for mandibular progathism, and as a diagnostic tool in correlating the mandibular growth with causal relations between hormones and craniofacial development. How to cite this article Premkumar S, Gurumurthy B. Assessment of 2D:4D in Subjects with Anteroposterior Mandibular Dysplasia. J Contemp Dent Pract 2013;14(4):582-585.

scholarly journals Effect of the ketoprofen on the preemptive analgesia in female cats undergoing to ovariohysterectomy

Revista CERES ◽  
2017 ◽  
Vol 64 (1) ◽  
pp. 18-24
Author(s):  
Dayvid Vianêis Farias de Lucena ◽  
Fernanda Vieira Henrique ◽  
Amara Gyane Alves de Lima ◽  
Almir Pereira de Souza ◽  
Pedro Isidro da Nóbrega Neto
Keyword(s):  
Statistical Analysis ◽  
Preemptive Analgesia ◽  
Pain Scores ◽  
Significant Difference ◽  
Reduction Of Pain ◽  
Baseline Values ◽  
Student’S T ◽  
Level Of Significance ◽  
Postoperative Administration ◽  
Student’S T Test

ABSTRACT The objective of this study was to investigate the effect of the ketoprofen on the preemptive analgesia in female cats submitted to ovariohysterectomy. Sixteen healthy cats were distributed into two groups, with eight animals each, by means of a draw, in a preemptive group (PREG), in which the animal received ketoprofen (1 mg/kg) subcutaneously two hours before the surgery; and postsurgery group (POSG), in which ketoprofen (1 mg/kg) was administered subcutaneously immediately after surgery. In both groups, ketoprofen was given 24, 48 and 72 hours after the first adminstration. Heart and respiratory frequencies and glycemia were measured in all animals during the days first ten postsurgery. Analgesia was measured by assigning scores at zero, two, four, six, 12, 24, 48, 72, 96, 120, 144, 168, 192, 216 and 240 hours after the surgical procedure. Statistical analysis was performed using two-way analysis of variance followed by Tukey's test to compare the moments and Student's t-test for comparison between groups. Pain scores were evaluated using test of U-Mann-Withney or Kruskall-Wallis, all at the 5% level of significance. Pain scores were significantly lower in PREG in M0, M6, M72, M96 and M120. No significant difference was found in the levels of glycemia in comparison to baseline values. Ketoprofen promotes postsurgery analgesia in female cats submitted to ovariohysterectomy and preemptive and postsurgery administration provides an earlier reduction of pain scores when compared to postoperative administration, only.

scholarly journals Respiratory changes in Parkinson's disease may be unrelated to dopaminergic dysfunction

2012 ◽  
Vol 70 (11) ◽  
pp. 847-851 ◽  
Author(s):  
Luciana Ulhôa Guedes ◽  
Juliana Melo Rodrigues ◽  
Aline Andrioni Fernandes ◽  
Francisco E. Cardoso ◽  
Verônica Franco Parreira
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Statistical Analysis ◽  
Healthy Controls ◽  
Maximal Inspiratory Pressure ◽  
Age And Gender ◽  
Dopaminergic Dysfunction ◽  
And Gender ◽  
Student’S T ◽  
Student’S T Test

OBJECTIVE: To investigate the maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) in patients with Parkinson's disease (PD) during the on and off periods of levodopa and to compare with healthy controls. METHODS: Twenty-six patients were analyzed with Hoehn and Yahr scores (2-3) and 26 age and gender matched-controls. Statistical analysis was performed with Student's t-test for paired and independent samples. RESULTS: MIP and MEP values in patients were significantly lower than the values obtained in controls both for off and on stages -excepted for MIP in women (p=0.28). For patients with PD, the studied parameters did not differ between stages on and off, with the exception of MEP in women (p=0.00). CONCLUSIONS: Patients with PD have respiratory pressure lower than controls, even in early stages of the disease, and dopamine replacement has little impact over these respiratory pressures. These findings suggest that respiratory changes in PD may be unrelated to dopaminergic dysfunction.

scholarly journals Study of Relationship of Anemia among Edentulous Patients

2018 ◽  
Vol 5 (2) ◽  
pp. 105-108
Author(s):  
Lijo Isaac ◽  
A. P. Nirmal Raj ◽  
Reshma Karkera ◽  
R Naveen Reddy
Keyword(s):  
Nutritional Status ◽  
T Test ◽  
Dental Status ◽  
Adult Patients ◽  
Control Group ◽  
Age Group ◽  
Edentulous Patients ◽  
Student’S T ◽  
Relationship Of ◽  
Student’S T Test

Very little studies were done on relationship of the dental status and the nutritional status. The present study was done to study relation between edentulism and the presence of anemia. The study was included of 46 adult patients with edentulism and same numbers of patients were taken as controls. The results were tabulated and analyzed with the help of IBM SPSS statistics 20 using student’s t test. The hemoglobin levels were lower in the edentulous patients that that of the control group. The present study had shown that the nutritional status were poor resulting in anemia in case of edentulous patients as compared to control group with the same age group.  

scholarly journals The influence of proteinuria on tubular transport of Na+, K+, CL

2002 ◽  
Vol 130 (3-4) ◽  
pp. 64-67
Author(s):  
Dejan Petrovic ◽  
Radmila Obrenovic ◽  
Mileta Poskurica ◽  
Biljana Stojimirovic
Keyword(s):  
Statistical Analysis ◽  
Creatinine Clearance ◽  
Significant Influence ◽  
Fractional Excretion ◽  
T Test ◽  
The Third ◽  
Tubular Transport ◽  
Student’S T ◽  
Student’S T Test

Functional and structural damages of tubulointerstitium are caused by proteinuria. The aim of this study was to assess the influence of different proteinuria levels on Na+, K+, Cl tubular transport. We examined 50 patients (24 males, 26 females), mean age 46.50 ? 13.08 years, with mean creati-nine clearence of 87.29 ? 31.17 mL/min. They were separated in three groups depending on proteinuria value. The first group with proteinuria less than 0.3 g/24h included 19 persons (7 males, 12 females), mean age 45.12 ? 13.28 years, with mean creatinine clearance of 94.27 ? 34.70 mL/min. The second group of 18 patients (8 males, 10 females), mean age 45.39 ? 12.64 years had proteinuria of 0.3-3,0 g/24h and mean creatinine clearance of 90.07 ? 31.89 mL/min. The third group had proteinuria level higher than 3.0g/24h and mean creatinine clearance of 73.25 ? 20.44 mL/min. It included 13 patients (9 males, 4 females), mean age 50.08 ? 13.73 years. As a parameter of proteinuria influence on tubular transport of Na+, K+ and Cl-, fractional excretion of these electrolytes, was studied. Student's T test, Mann Whitney U test and c2 test were used for statistical analysis. No statistically significant influence of proteinuria was found on Na+, K+ and Cl tubular transport.

Dr. Arnaud Replies

PEDIATRICS ◽  
1977 ◽  
Vol 60 (5) ◽  
pp. 761-761
Author(s):  
Sara B. Arnaud
Keyword(s):  
Vitamin D ◽  
Statistical Analysis ◽  
Vitamin D Deficiency ◽  
Statistical Comparison ◽  
Hydroxyvitamin D ◽  
Number Of Patients ◽  
25 Hydroxyvitamin D ◽  
Deficiency Rickets ◽  
Student’S T ◽  
Student’S T Test

Drs. Giangiacomo and Gleason are quite correct in their criticism that the number of patients with vitamin D deficiency rickets is too small for statistical comparison of the concentration of serum 25-hydroxyvitamin D (25-OH-D) in mild, moderate, and severe rickets. For this reason, we did not attempt this type of statistical comparison (Student's t test). The statistical analysis which supports our conclusion is the calculation of the regression between senim 25-OH-D, ng/ml and the stage of the disease, designated by arbitrary numbers 1, 2, and 3 for mild, moderate, and severe.

Incipient Release of Leukocytes After Allogeneic Hematopoietic Cell Transplantation Is Indicated by Increasing Serum Levels of Uric Acid Before Detection of First Leukocytes

Blood ◽  
2010 ◽  
Vol 116 (21) ◽  
pp. 4701-4701
Author(s):  
Sebastian P. Haen ◽  
Vicky Eyb ◽  
Lothar Kanz ◽  
Wolfgang A. Bethge
Keyword(s):  
Uric Acid ◽  
Cell Transplantation ◽  
Peripheral Blood ◽  
Conditioning Regimen ◽  
Serum Levels ◽  
T Test ◽  
Allogeneic Hct ◽  
Student’S T ◽  
Student’S T Test ◽  
Group 1

Abstract Abstract 4701 Uric acid serves as an endogenous danger signal to the immune system upon the release from dying cells activating both innate and adaptive immunity. Multiple cytokines and danger signals are released into the blood modulating cellular and humoral immune responses during haematopoietic cell transplantation (HCT). Here, we investigated serum levels of uric acid during haematopoietic regeneration after allogeneic HCT to evaluate whether uric acid can be used as marker for hematopoietic engraftment indicating immunologic activity below the detection limit of differential blood counts (50/μ l). Differential blood counts and serum levels of uric acid, creatinine and urea were retrospectively analyzed in 47 consecutive patients (22 men and 25 women, median age 48 years, range 19 to 73 years) during 50 allogeneic HCT (three patients received a second transplantation due to recurrent disease). Serum levels of uric acid, creatinine and peripheral blood counts were determined daily. All patients received allopurinol for 5 days from the beginning of the conditioning which was discontinued afterwards. The mean nadir in uric acid levels was observed 13.4 days after the last dose of allopurinol (range 2 to 32 days) and 9.1 days after transplantation (range 2 to 21 days) irrespective of the conditioning regimen used. In all patients a significant decrease of uric acid serum levels after the transplantation was observed (Student's t-test, p < 0.001). A re-increase of uric acid was observed 1 to 10 days (mean 4.1 days, SD 2.4) before detection of white blood cells (leukocytes > 50/μ L) in 35 out of 50 transplantations (70%, group 1). In three cases (6%), the increase of uric acid levels was observed concomitantly with increasing leukocytes (group 2). In the remaining 12 cases, this elevation was only observed later (1 to 6 days after re-increase of leukocytes, mean 2.8 days, SD 1.5, group 3). The difference between group 1 and 3 was statistically significant (Student's t-test, p < 0.001). No correlation with patient age, conditioning regimen, HLA compatibility or additional medications could be observed. Therefore, a re-increase of uric acid can be indicative for incipient haematopoietic engraftment after allogeneic HCT and may serve as indicator for consumption of the ealiest differentiated cells in peripheral blood even before leukocytes can be detected. Disclosures: No relevant conflicts of interest to declare.

An Aphid Sex Attractant

1970 ◽  
Vol 1 (1) ◽  
pp. 63-73 ◽  
Author(s):  
Jan Pettersson
Keyword(s):  
Statistical Analysis ◽  
Sex Attractant ◽  
T Test ◽  
Chemical Signal ◽  
Larval Instars ◽  
Student’S T ◽  
Student’S T Test

AbstractThe experiments described have given the following conclusions: (I) A chemical signal (pheromone) emitted by the oviparous female has an attractive effect upon the males. This signal is not emitted by the virginogeniae. (2) The signal is emitted by organs situated on the hind tibiae of the oviparous female and perceived by organs on the male antennae. (3) The substance is only emitted by the females during a certain period in their lifetime. Apparently, this is principally the condition which has been called active copulatory period (ACP). No emittance was found neither during the passive precopulatory period (PPP) nor during the passive postcopulatory period (PCP). (4) Males are capable of detecting and reacting to the signal already in the last two larval instars. (5) The males do not emit any substance affecting other males. Statistical analysis (Student's t-test) of the material has been excluded as it gave significance only in experiments where differences between the stimuli are apparent.

scholarly journals Fluoride Exposure through Different Drinking Water Sources in a Contaminated Basin in Guanajuato, Mexico: A Deterministic Human Health Risk Assessment

2021 ◽  
Vol 18 (21) ◽  
pp. 11490
Author(s):  
Paulina Farías ◽  
Jesús Alejandro Estevez-García ◽  
Erika Noelia Onofre-Pardo ◽  
María Luisa Pérez-Humara ◽  
Elodia Rojas-Lima ◽  
...  
Keyword(s):  
Drinking Water ◽  
Health Risks ◽  
Dental Fluorosis ◽  
Water Source ◽  
Water Sources ◽  
Drinking Water Source ◽  
Drinking Water Sources ◽  
Fluoride Exposure ◽  
Urinary Fluoride ◽  
Water Fluoride

Water fluoride levels above the World Health Organization’s guideline (1.5 mg/L), common in overexploited aquifers, represent a health hazard. Our objective was to assess the health risks posed by exposure to fluoride in different drinking water sources in a contaminated basin in Mexico. Fluoride was measured in mutual drinking water sources and in the urine of 39 children and women. Risks were estimated through hazard quotient (HQ) by drinking water source. Dental fluorosis was assessed in the children. Mean fluoride water concentrations (mg/L) were: well, 4.2; waterhole, 2.7; bottled, 2.1; rainwater, 0.4. The mean urinary fluoride concentrations (specific gravity adjusted) were 2.1 mg/L and 3.2 mg/L in children and women, respectively. Our multiple linear regression model showed children’s urinary fluoride concentrations increased 0.96 mg/L for every 1 mg/L increase in water fluoride (p < 0.001). Dental fluorosis was diagnosed in 82% of the children, and their HQ according to drinking water source was: well, 1.5; waterhole, 1.1; bottled, 0.8; harvested rainwater, 0.3. The pervasive dental fluorosis indicates a toxic past fluoride exposure; urinary fluoride levels and HQs indicate high exposure and current health risks for most children. Drinking harvested rainwater will likely prevent most of the local fluoride exposure.

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