Association between the use of electronic cigarettes and the prevalence of chronic rhinosinusitis and allergic rhinitis: a nationwide cross-sectional study

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
M.-S. Rha ◽  
H.-J. Cho ◽  
J.-H. Yoon ◽  
C.-H. Kim
Keyword(s):  
Allergic Rhinitis ◽  
Chronic Rhinosinusitis ◽  
Electronic Cigarettes ◽  
Adult Population ◽  
Upper Airway ◽  
Airway Disease ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
High Prevalence

Background: Whether the use of electronic cigarettes (ECs) is associated with upper airway diseases, including chronic rhinosinusitis (CRS) and allergic rhinitis (AR), remains unclear. Methods: We analyzed data from the nationwide cross-sectional surveys: the Korea National Health and Nutrition Examination Survey VI (2013–2015), VII (2016–2018), and VIII (2019). Logistic regression analysis was performed to assess the association between EC use and CRS or AR. Results: Among a total of 38,413 participants, 6.4% were former EC users and 2.5% were current EC users. Former EC users and current EC showed a significantly increased OR for CRS or AR compared with never EC users. In the subgroup analysis, the “current CC (conventional cigarette)-current EC” and the “current CC-formal EC” group had a significantly higher OR for CRS or AR than the “current CC-never EC” group. In addition, former CC smokers who currently use ECs showed a significantly higher OR for AR than former CC smokers without EC use. Conclusions: EC use is significantly associated with a high prevalence of CRS and AR in the adult population. These results indicate that the use of ECs may increase the risk of upper airway disease.

scholarly journals PTSD prevalence among resident mothers and their offspring in Rwanda 25 years after the 1994 genocide against the Tutsi

2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Celestin Mutuyimana ◽  
Vincent Sezibera ◽  
Epaphrodite Nsabimana ◽  
Lambert Mugabo ◽  
Cindi Cassady ◽  
...  
Keyword(s):  
Traumatic Event ◽  
Adult Population ◽  
Cross Sectional Study ◽  
Ptsd Symptoms ◽  
Target Groups ◽  
Cross Sectional ◽  
High Prevalence ◽  
General Adult Population ◽  
Exposure To Trauma ◽  
Ptsd Prevalence

Abstract Background The 1994 Genocide against the Tutsi was a major traumatic event affecting nearly all Rwandans. Significant psychological sequels continue to occur in the population 25 years after, with a high prevalence of posttraumatic stress disorder (PTSD) found in women. Three groups are typically designated with regard to the Genocide against the Tutsi: those who were targeted and categorized as genocide “survivors,” those who were in the country during the genocide and were the “non-targeted” group, and those who were outside of the country, referred to as the “1959 returnees.” Each group experienced various traumatic events during and in the aftermath of the genocide. Offspring of the designated groups, currently exhibit symptoms of PTSD disregarding of being born in the years following the genocide. A number of studies have described the prevalence of PTSD in the general adult population. There is a lack of research comparing the prevalence of PTSD in women and their offspring among these three target groups, therefore, this study aimed to bridge the gap. Methods We conducted a comparative cross-sectional study with a sample of 432 mothers and 432 children in three categories: genocide survivors, in country non-targeted and 1959 returnees. Participant ages for children were between 14 to 22 years and for mothers, between the ages of 32 to 87 years. The UCLA-PTSD DSM-5, PTSD Check list-5 and Life events Checklist-5 were translated from English to Kinyarwanda and were used to assess exposure to trauma and the prevalence of PTSD symptoms in Rwandan mothers and their offspring. Results Key Results yield a PTSD rate of 18.8, 6.2, 5.2% within survivors, in country non-targeted, and returnees respectively with an average PTSD rate of 43.8% for parents, and 16.5% for offspring. Conclusion PTSD among the mothers’ groups and their offspring have been found, specifically in the offspring of genocide survivors. Considering these adolescents were not born at the time of the 1994 Genocide against the Tutsi, the results suggest future studies should explore the precipitating factors contributing to the PTSD symptoms within this specific group.

scholarly journals Allergic rhinitis, part of the allergic respiratory syndrome

2020 ◽  
Vol 73 (9-10) ◽  
pp. 301-308
Author(s):  
Aleksandra Aleksic ◽  
Mirjana Gnjatic ◽  
Mirjana Stupar-Hofman ◽  
Vesna Tomic-Spiric
Keyword(s):  
Allergic Rhinitis ◽  
Chronic Rhinosinusitis ◽  
Immunoglobulin E ◽  
Otitis Media With Effusion ◽  
Systemic Disease ◽  
Positive Family History ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Statistical Analysis System ◽  
Analysis System

Introduction. Diseases associated with immunoglobulin E hypersensitivity, such as allergic rhinitis, may have different clinical expressions. Patients with allergic rhinitis often have associated diseases, comorbidities, which supports the concept of allergy as a systemic disease. The aim of this study was to evaluate the incidence and types of comorbidities in allergic rhinitis. We also evaluated the possible effects of certain clinical and demographic parameters on the onset of comorbidities. Material and Methods. This retrospective, observational, and cross-sectional study included patients with a clinical diagnosis of allergic rhinitis treated at the Department of Ear, Nose and Throat in the period from October 2011 to April 2013. The collected data were analyzed using the Statistical Analysis System (Institute Inc. NC, USA) program, version 9.1.3. Results. The study included 319 patients with allergic rhinitis. Allergic rhinitis was intermittent in 30.7% of cases, persistent in 37.9%, and persistent with seasonal exacerbation in 31.3% of patients. We found that 86.8% of patients had some form of comorbidity. The most common were conjunctivitis (50.2%), almost equal percentage of asthma (29.8%) and chronic rhinosinusitis (28.8%), followed by otitis media with effusion (8.8%), atopic dermatitis (5.2%), urticaria (4.1%), and laryngitis (3.8%). Persistent allergic rhinitis, with persistent nasal obstruction as the dominant symptom, was significantly associated with chronic rhinosinusitis. Positive family history was significantly associated with the occurrence of asthma and allergic rhinitis. Conclusion. The results of our study showed that allergic rhinitis is rarely an isolated condition and it should always be observed in the context of the allergic respiratory syndrome.

scholarly journals The Prevalence of Allergic Rhinitis, Eczema and Asthma in Students of Guidance Schools in Mazandaran Province, Iran

2016 ◽  
Vol 4 (4) ◽  
pp. 619-623 ◽  
Author(s):  
Daniel Zamanfar ◽  
Javad Ghaffari ◽  
Salar Behzadnia ◽  
Jamshid Yazdani-charati ◽  
Sahar Tavakoli
Keyword(s):  
Allergic Rhinitis ◽  
Cross Sectional Study ◽  
Caesarian Section ◽  
Sectional Study ◽  
Mazandaran Province ◽  
Cross Sectional ◽  
High Prevalence ◽  
History Of ◽  
Spss Software ◽  
Allergic Disorders

BACKGROUND: Eczema, allergic rhinitis and asthma are common chronic allergic disorders in childhood.AIM: The aim of this study was to determine the prevalence of common allergic disorders among Iranian guidance schools students in Mazandaran Province, northern Iran.METHODS: This analytical cross-sectional study was performed on 3000 children aged 11‐14 years old during 2012‐13 according to ISAAC study. Of 3000 recruited children 1576 (52.54%) were female and 1424 (47.46%) were male. Data gathered by ISAAC first phase questionnaire analysed by SPSS software 20.RESULTS: The prevalence of wheezing, allergic rhinitis symptoms (sneezing and pruritus) and atopic dermatitis symptoms (pruritus skin lesion) were 30.5%, 30% and 15% respectively. History of pets contact and smoking was positive 6.6% and 36 % respectively. About 52% was born with caesarian section. There was wheezing in 32.5% during sport. The diagnosis of asthma, allergic rhinitis and eczema were 12.2%, 28.5% and 15% respectively. Eczema, asthma and allergic rhinitis were significantly more common in boys students (p < 0.05).CONCLUSIONS: The results of this study showed that asthma, allergic rhinitis and eczema have a high prevalence and they are more common in boys.

scholarly journals Bi-directional association between allergic rhinitis and diabetes mellitus from the national representative data of South Korea

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tae Kyung Lee ◽  
Ye Jin Jeon ◽  
Sun Jae Jung
Keyword(s):  
Diabetes Mellitus ◽  
Sensitivity Analysis ◽  
Allergic Rhinitis ◽  
Cross Sectional Study ◽  
Study Data ◽  
Sectional Study ◽  
Medication History ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
Hba1c Levels

AbstractAllergic rhinitis (AR) and diabetes mellitus (DM) share a common cause in inflammation; however, potential relationships between them are not clear. Therefore, we aimed to explore the associations between AR and DM. In this cross-sectional study, data were extracted from the Korean National Health and Nutrition Examination Survey 2007–2018 and weighted based on sociodemographic characters. AR and DM were defined by diagnoses thereof. Since self-reporting was not perfect, in order to complement the validity, we additionally performed sensitivity analysis by defining DM according to HbA1c and medication history. After excluding invalid data, the number of final participants was 29,246 (mean age, 54.95 ± 14.27 years). We calculated the odds ratio (OR) of newly self-reported DM among AR patients without DM history by multivariable logistic regression adjusted for potential confounders. A reverse association was also assessed. Patients with AR showed lower ORs for DM than those without AR (OR, 95% CI: men, 0.28, 0.19–0.42; women, 0.33, 0.24–0.46). Similarly, DM patients showed lower ORs for AR than patients without DM (men, 0.41, 0.31–0.56; women, 0.34, 0.25–0.46). The same results were obtained in sensitivity analysis defining DM according to HbA1c levels or DM treatment and in stratification analysis for age, residency, comorbidity, BMI, and menopause. In conclusion, we discovered that AR and DM show mutual inverse associations, regardless of sex, in individuals aged 30 years and older.

scholarly journals Negative Association between Acrylamide Exposure and Metabolic Syndrome Markers in Adult Population

2021 ◽  
Vol 18 (22) ◽  
pp. 11949
Author(s):  
Chun-Chi Hung ◽  
Yung-Wen Cheng ◽  
Wei-Liang Chen ◽  
Wen-Hui Fang
Keyword(s):  
Metabolic Syndrome ◽  
Animal Studies ◽  
Adult Population ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Environmental Chemicals ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
High Fasting Plasma Glucose ◽  
Adjusted Model

Metabolic syndrome encompasses multiple conditions that increase the risk of cardiovascular disease, and exposure to environmental chemicals can cause metabolic syndrome. This cross-sectional study analyzed data from the US National Health and Nutrition Examination Survey (2003–2006) on 4318 adult participants to assess the association between acrylamide (AA) exposure and metabolic syndrome. Concentrations of hemoglobin-adducted AA (HbAA) and hemoglobin-adducted glycidamide (HbGA) were evaluated. Metabolic syndrome markers related to HbAA and HbGA and the effect of exposure to AA and GA on the prevalence of metabolic syndrome were studied by ANOVA and multivariate logistic regression analyses, respectively. HbAA concentration inversely correlated with the number of metabolic syndrome markers (p < 0.05). An increased HbAA concentration was noted with reduced high triglyceride and low high-density lipoprotein cholesterol levels in the adjusted model (p < 0.05). High fasting plasma glucose level significantly correlated with HbGA concentration in the adjusted model. In conclusion, AA exposure alters metabolic syndrome markers in adults. Additional clinical and animal studies will clarify the role of AA exposure at different stages in the progression of metabolic syndrome-related diseases.

Nasal polyposis in patients with asthma and allergic rhinitis

2012 ◽  
Vol 126 (8) ◽  
pp. 780-783 ◽  
Author(s):  
A Ahmadiafshar ◽  
H R Farjd ◽  
F Moezzi ◽  
N Mousavinasab
Keyword(s):  
Allergic Rhinitis ◽  
Nasal Polyps ◽  
Nasal Polyposis ◽  
Asthma Severity ◽  
Cross Sectional Study ◽  
Endoscopic Examination ◽  
Concomitant Treatment ◽  
Cross Sectional ◽  
High Prevalence ◽  
The Impact

AbstractObjective:This study aimed to determine the prevalence of nasal polyps in patients with allergic rhinitis and with asthma, and also to assess the impact of this condition on these disorders.Study design:Cross-sectional study.Methods:The presence of nasal polyps was assessed by rhinoscopy and endoscopic examination.Results:Nasal polyps were detected in 60 out of 250 patients (24 per cent) with documented asthma or allergic rhinitis. There was a statistically significant correlation between asthma severity and nasal polyposis prevalence (p = 0.007), but not between allergic rhinitis severity and nasal polyposis prevalence (p = 0.081). The prevalence of nasal polyps increased significantly with increasing patient age and rhinitis or asthma duration.Conclusion:The prevalence of nasal polyps in patients with allergic rhinitis or asthma was higher than previously reported. Given this high prevalence of nasal polyposis, nasal examination and concomitant treatment of this disorder are recommended.

scholarly journals High Prevalence of Thyroid Antibodies in Urban Population of Peninsular Malaysia

2020 ◽  
Vol 19 (2) ◽  
Author(s):  
Shahar MA ◽  
Omar AM ◽  
AB Wahab N ◽  
Sukor N ◽  
Kamaruddin NA
Keyword(s):  
Rural Areas ◽  
Adult Population ◽  
Cross Sectional Study ◽  
Peninsular Malaysia ◽  
Thyroid Antibodies ◽  
Cross Sectional ◽  
Autoimmune Thyroid ◽  
High Prevalence ◽  
Physical Examinations ◽  
Sociodemographic Profile

INTRODUCTION: Thyroid antibodies are closely related to autoimmune thyroid disorders. To date, there are no data on the prevalence of these antibodies among the Malaysian population. This study aimed to determine the prevalence of thyroid antibodies; and the factors associated with thyroid antibodies in the Malaysian adult population. MATERIALS AND METHODS: A cross-sectional study was performed in 5 preassigned regions in Peninsular Malaysia. Participants’ sociodemographic profile and medical history were recorded. Physical examinations were done looking for abnormalities of the thyroid gland and signs of thyroid dysfunctions. Fifteen mils of blood were withdrawn and analysed for thyroid function, anti-thyroperoxidase (anti-TPO) and anti-thyroglobulin (anti-TG) antibodies at a central laboratory. RESULTS: Among the total of 2190 respondents, the overall prevalence of positive anti-TPO and anti-TG antibodies were 12.2% and 12.1%, respectively; mainly found in urban and coastal areas. Only 7% to 9% of those with positive anti-TPO or antiTG antibodies had either hypo- or hyperthyroidism. The predictors for positive anti-TPO antibody were female [adjusted OR 1.7 (95%CI: 1.2–2.4); p=0.001], Indian [adjusted OR 1.9 (95%CI: 1.1–3.1); p=0.020], and having a goitre [adjusted OR 1.8 (95%CI: 1.2–2.8), p=0.004]. The predictors of positive anti-TG antibody was female [adjusted OR 2.3 (95%CI: 1.6–3.3); p<0.001], and having a goitre [adjusted OR 2.0 (95%CI: 1.3–3.4), p=0.001]. Those living in rural areas had 38% lower risk of having positive anti-TG. CONCLUSIONS: The prevalence of positive anti-TPO and anti-TG antibodies were 12.2% and 12.1%, respectively; were higher among the urban and coastal populations. Those living in rural areas had lower risks of anti-TG antibody.

scholarly journals Epidemiology of Chlamydia pneumoniae infection in a randomly selected population in a developed country

1999 ◽  
Vol 122 (1) ◽  
pp. 111-116 ◽  
Author(s):  
C. O'NEILL ◽  
L. J. MURRAY ◽  
G. M. L. ONG ◽  
D. P. J. O'REILLY ◽  
A. E. EVANS ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Chlamydia Pneumoniae ◽  
Economic Status ◽  
Adult Population ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Developed Country ◽  
High Prevalence ◽  
Prevention Of Cardiovascular Disease

This cross-sectional study of 400 sera from a randomly selected adult population in Northern Ireland, using a microimmunofluorescence assay, demonstrated high overall seropositivity (70%) for IgG Chlamydia pneumoniae antibodies in developed populations. Seropositivity was shown to be unrelated to gender, age or smoking but there was an inverse trend between infection and educational level achieved as a measure of socio-economic status. IgG levels were also higher during the winter months suggesting seasonal variation of Chlamydia pneumoniae infection. The high prevalence of evidence of exposure to Chlamydia pneumoniae as described in this study may have implications for prevention of cardiovascular disease if further evidence conclusively determines that infection with this organism is a risk factor for cardiovascular disease.

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