Making reconnections in agro-food geography: alternative systems of food provision

The Rural ◽  
2017 ◽  
pp. 165-184
Author(s):  
D.C.H. Watts ◽  
B. Ilbery ◽  
D. Maye
2005 ◽  
Vol 29 (1) ◽  
pp. 22-40 ◽  
Author(s):  
D. C. H. Watts ◽  
B. Ilbery ◽  
D. Maye

Author(s):  
W. O. Saxton

Recent commercial microscopes with internal microprocessor control of all major functions have already demonstrated some of the benefits anticipated from such systems, such as continuous magnification, rotation-free diffraction and magnification, automatic recording of mutually registered focal series, and fewer control knobs. Complete automation of the focusing, stigmating and alignment of a high resolution microscope, allowing focal series to be recorded at preselected focus values as well, is still imminent rather than accomplished, however; some kind of image pick-up and analysis system, fed with the electron image via a TV camera, is clearly essential for this, but several alternative systems and algorithms are still being explored. This paper reviews the options critically in turn, and stresses the need to consider alignment and focusing at an early stage, and not merely as an optional extension to a basic proposal.


Author(s):  
Kavitha K ◽  
Asha S ◽  
Hima Bindu T.V.L ◽  
Vidyavathi M

The safety and efficacy of a drug is based on its metabolism or metabolite formed. The metabolism of drugs can be studied by different in vitro models, among which microbial model became popular. In the present study, eight microbes were screened for their ability to metabolize phenobarbital in a manner comparable to humans with a model to develop alternative systems to study human drug metabolism. Among the different microbes screened, a filamentous fungi Rhizopus stolonifer metabolized phenobarbital to its metabolite which is used for further pharmacological and toxicological studies. The transformation of phenobarbital was identified by high- performance liquid chromatography (HPLC). Interestingly, Rhizopus stolonifer sample showed an extra metabolite peak at 3.11min. compared to its controls. The influence of different carbon sources in media used for growth of fungus, on metabolite production was studied, to find its effect in production of metabolite as the carbon source may influence the growth of the cell.


2020 ◽  
Vol 14 (1) ◽  
pp. 21-39
Author(s):  
Anupama Singh ◽  
Vandana Kharb ◽  
Vikas Anand Saharan

Fast Dissolving/Disintegrating Dosage Forms (FDDFs) are a group of dosage forms which dissolve or disintegrate quickly, leading to fast distribution of active ingredients at the site of administration; thereby providing ease of oral ingestion of solid unit dosage forms and have the potential to enhance transmucosal absorption. With time, the use of FDDFs in alternative systems has significantly increased. Homeopathic systems and traditional Chinese medicine have embraced FDDFs for the delivery of active compounds. Most of the patents in this area are from China or by the Chinese innovators. In Europe and US, FDDFs have been extensively studied for the delivery of natural active compounds. It was fascinating to know that some new dosage forms and new routes of delivering active compounds are also making their way to the family of FDDFs. The dose of active compound, size of dosage forms, standardization of extracts, polyherbal mixtures, stability of active compounds, safety, efficacy and pharmacokinetics are challenging issues for developing FDDF herbal formulations or phytopharmaceuticals.


Biomolecules ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1072
Author(s):  
Raquel Cid ◽  
Jorge Bolívar

To date, vaccination has become one of the most effective strategies to control and reduce infectious diseases, preventing millions of deaths worldwide. The earliest vaccines were developed as live-attenuated or inactivated pathogens, and, although they still represent the most extended human vaccine types, they also face some issues, such as the potential to revert to a pathogenic form of live-attenuated formulations or the weaker immune response associated with inactivated vaccines. Advances in genetic engineering have enabled improvements in vaccine design and strategies, such as recombinant subunit vaccines, have emerged, expanding the number of diseases that can be prevented. Moreover, antigen display systems such as VLPs or those designed by nanotechnology have improved the efficacy of subunit vaccines. Platforms for the production of recombinant vaccines have also evolved from the first hosts, Escherichia coli and Saccharomyces cerevisiae, to insect or mammalian cells. Traditional bacterial and yeast systems have been improved by engineering and new systems based on plants or insect larvae have emerged as alternative, low-cost platforms. Vaccine development is still time-consuming and costly, and alternative systems that can offer cost-effective and faster processes are demanding to address infectious diseases that still do not have a treatment and to face possible future pandemics.


Energies ◽  
2021 ◽  
Vol 14 (5) ◽  
pp. 1215
Author(s):  
Alvaro Carreno ◽  
Marcelo Perez ◽  
Carlos Baier ◽  
Alex Huang ◽  
Sanjay Rajendran ◽  
...  

Distribution systems are under constant stress due to their highly variable operating conditions, which jeopardize distribution transformers and lines, degrading the end-user service. Due to transformer regulation, variable loads can generate voltage profiles out of the acceptable bands recommended by grid codes, affecting the quality of service. At the same time, nonlinear loads, such as diode bridge rectifiers without power factor correction systems, generate nonlinear currents that affect the distribution transformer operation, reducing its lifetime. Variable loads can be commonly found at domiciliary levels due to the random operation of home appliances, but recently also due to electric vehicle charging stations, where the distribution transformer can cyclically vary between no-load, rated and overrated load. Thus, the distribution transformer can not safely operate under highly-dynamic and stressful conditions, requiring the support of alternative systems. Among the existing solutions, hybrid transformers, which are composed of a conventional transformer and a power converter, are an interesting alternative to cope with several power quality problems. This article is a review of the available literature about hybrid distribution transformers.


2021 ◽  
Vol 46 (2) ◽  
pp. 160-171
Author(s):  
Kelly Rose ◽  
Claire O’Malley ◽  
Laura Brown ◽  
Louisa Jane Ells ◽  
Amelia A. Lake

1988 ◽  
Vol 135 ◽  
Author(s):  
Michael M Thackeray

AbstractConsiderable efforts are in progress to develop rechargeable batteries as alternative systems to the nickel-cadmium battery. In this regard, several advances have been made in ambient-temperature lithium battery technology, and specifically in the engineering of rechargeable lithium/manganese dioxide cells. This paper reviews the current state of the art in rechargeable Li/MnO2battery technology; particular attention is paid to the structural features of various MnO2electrode materials which influence their electrochemical and cycling behaviour in lithium cells.


The Monist ◽  
1934 ◽  
Vol 44 (1) ◽  
pp. 144-146 ◽  
Author(s):  
Y. L. Chin ◽  
Keyword(s):  

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