Valvular heart diseases. (2). Long term prognosis of patients with mitral stenosis undergoing open mitral commisurotomy. With special reference to their quality of life.

Background: Sepsis and sepsis-associated encephalopathy (SAE) are common intensive care unit (ICU) diseases; the morbidity and mortality are high. The present study analyzed the sensitivity of different diagnostic criteria of sepsis 1.0 and 3.0, epidemiological characteristics of sepsis and SAE, and explored its risk factors for death, short-term, and long-term prognosis. Methods: The retrospective study included patients in ICU from January 2015 to June 2016. After excluding 58 patients, 175 were assigned to either an SAE or a non-SAE group (patients with sepsis but no encephalopathy). The sensitivity of the diagnostic criteria was compared between sepsis 1.0 and 3.0, respectively. Between-group differences in baseline data, Acute Physiology and Chronic Health Evaluation II score (APACHE II score), Sequential Organ Failure Assessment score (SOFA score), etiological data, biochemical indicators, and 28-day and 180-day mortality rates were analyzed. Survival outcomes and long-term prognosis were observed, and risk factors for death were analyzed through 180-day follow-up. Results: The sensitivity did not differ significantly between the diagnostic criteria of sepsis 1.0 and 3.0 ( P = .286). The 42.3% incidence of SAE presented a significantly high APACHE II and SOFA scores as well as 28-day mortality and 180-day mortality (all P < .001). The incidence of death was 37.1%. The multivariate stepwise regression analysis demonstrated that the risk of death in SAE group was significantly higher than the non-SAE group ( P < .001). Sepsis-associated encephalopathy is a risk factor for sepsis-related death (relative risk [RR] = 2.868; 95% confidence interval: 1.730-4.754; P < .001). Although males showed a significantly high rate of 28-day and 180-day mortality ( P = .035 and .045), it was not an independent risk factor for sepsis-related death ( P = .072). The long-term prognosis of patients with sepsis was poor with decreased quality of life. No significant difference was observed in prognosis between the SAE and non-SAE groups ( P > .05). Conclusion: Both diagnostic criteria cause misdiagnosis, and the sensitivity did not differ significantly. The incidence of SAE was high, and 28-day and 180-day mortality rates were significantly higher than those without SAE. Sepsis-associated encephalopathy is a risk factor for poor outcome. The overall long-term prognosis of patients with sepsis was poor, and the quality of life decreased.

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Symptoms, Hope, Self-Management Behaviors, and Quality of Life Among Chinese Preoperative Patient With Symptomatic Valvular Heart Diseases

Journal of Transcultural Nursing ◽

10.1177/1043659619864157 ◽

2019 ◽

Vol 31 (3) ◽

pp. 284-293 ◽

Cited By ~ 2

Author(s):

Yongfeng Chen ◽

Guifen Fu ◽

Fang Liang ◽

Jing Wei ◽

Jing He ◽

...

Keyword(s):

Quality Of Life ◽

Rural Areas ◽

Heart Diseases ◽

Adult Population ◽

Food Culture ◽

Self Management ◽

Valvular Heart Diseases ◽

Loss Of Appetite ◽

Management Behaviors

Introduction: More than 42 million people are estimated to suffer from valvular heart disease (VHD) worldwide with a prevalence of 5.3% to 7.7% in the Chinese adult population. The purpose of this study was to examine the associations between symptoms, hope, self-management behaviors, and quality of life (QOL) for preoperative patients with symptomatic VHD in a rural area of China. Method: This was a descriptive comparative study that took place in Nanning, China, between January 2015 and March 2016. The sample was 128 preoperative patients with symptomatic VHD. Data were collected using the Symptom Distress Questionnaire, Herth Hope Index, Self-Management Scale, and Minnesota Living with Heart Failure Questionnaire. Results: Data from 122 patients were included in the final analysis. Mean scores of hope, self-management, and QOL were 36.71, 55.27, and 55.56. Worse total scores of symptom severity ( r = 0.57 to 0.69, p < .001) and self-management behaviors ( r = −0.22 to −0.25, p < .05) were associated with poorer QOL. Fatigue, loss of appetite, and self-management behaviors explained 49.90% variance of QOL ( p < .001). Discussion: Fatigue, loss of appetite, and self-management influenced QOL of patients with symptomatic VHD. Interventions aimed at strengthening self-management and relieving symptoms should be tailored for patients with symptomatic VHD base on their traditional animist belief and food culture in rural areas of China such as the Zhuang Autonomous Region.

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Biomaterials in Valvular Heart Diseases

Frontiers in Bioengineering and Biotechnology ◽

10.3389/fbioe.2020.529244 ◽

2020 ◽

Vol 8 ◽

Author(s):

Bita Taghizadeh ◽

Laleh Ghavami ◽

Hossein Derakhshankhah ◽

Ehsan Zangene ◽

Mahdieh Razmi ◽

...

Keyword(s):

Quality Of Life ◽

Heart Disease ◽

Heart Diseases ◽

Low Cost ◽

Surgical Approaches ◽

Great Promise ◽

Therapeutic Approaches ◽

New Therapeutic Approaches ◽

Valvular Heart Diseases

Valvular heart disease (VHD) occurs as the result of valvular malfunction, which can greatly reduce patient’s quality of life and if left untreated may lead to death. Different treatment regiments are available for management of this defect, which can be helpful in reducing the symptoms. The global commitment to reduce VHD-related mortality rates has enhanced the need for new therapeutic approaches. During the past decade, development of innovative pharmacological and surgical approaches have dramatically improved the quality of life for VHD patients, yet the search for low cost, more effective, and less invasive approaches is ongoing. The gold standard approach for VHD management is to replace or repair the injured valvular tissue with natural or synthetic biomaterials. Application of these biomaterials for cardiac valve regeneration and repair holds a great promise for treatment of this type of heart disease. The focus of the present review is the current use of different types of biomaterials in treatment of valvular heart diseases.

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Long-Term Outcomes After Total Pancreatectomy: Special Reference to Survivors’ Living Conditions and Quality of Life

World Journal of Surgery ◽

10.1007/s00268-015-2948-1 ◽

2015 ◽

Vol 39 (5) ◽

pp. 1231-1239 ◽

Cited By ~ 28

Author(s):

Yusuke Watanabe ◽

Takao Ohtsuka ◽

Taketo Matsunaga ◽

Hideyo Kimura ◽

Koji Tamura ◽

...

Keyword(s):

Quality Of Life ◽

Special Reference ◽

Total Pancreatectomy ◽

Living Conditions ◽

Long Term Outcomes

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Utility of repeat head computed tomography after mild head trauma: influence on short- and long-term prognosis and health-related quality of life

Internal and Emergency Medicine ◽

10.1007/s11739-016-1421-y ◽

2016 ◽

Vol 12 (1) ◽

pp. 81-89 ◽

Cited By ~ 4

Author(s):

Francesca Innocenti ◽

Beatrice Del Taglia ◽

Irene Tassinari ◽

Federica Trausi ◽

Alberto Conti ◽

...

Keyword(s):

Quality Of Life ◽

Computed Tomography ◽

Health Related Quality ◽

Related Quality ◽

Health Related ◽

Short And Long Term ◽

Long Term Prognosis ◽

Head Computed Tomography

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A teljes nagyér-transzpozíción átesett betegek Senning- és Mustard-féle műtéti megoldásának hosszú távú utánkövetése. Eredmények a CSONGRAD Regiszterből

Orvosi Hetilap ◽

10.1556/650.2015.30337 ◽

2016 ◽

Vol 157 (3) ◽

pp. 104-110 ◽

Cited By ~ 1

Author(s):

Kálmán Havasi ◽

Anita Kalapos ◽

Krisztina Berek ◽

Péter Domsik ◽

Mária Kohári ◽

...

Keyword(s):

Quality Of Life ◽

Functional Capacity ◽

Heart Diseases ◽

Term Survival ◽

Mortality And Morbidity ◽

Significant Difference ◽

Long Term Follow Up

Introduction: Transposition of the great arteries is one of the most common cyanotic congenital heart diseases. Aim: The present study aimed to examine and compare long-term survival, functional grading, arrhytmologic and quality of life control in patients with transposition of the great arteries following Senning- and Mustard-operations. Methods: The present study comprised 85 patients with transposition of the great arteries, of whom Senning-operation was performed in 37 cases and Mustard-operation in 48 subjects. Follow-up study was performed in all cases. Results: The success rate of long-term follow-up proved to be 74%. Twelve out of the 31 Senning-operated and 16 out of 32 Mustard-operated patients died during the follow-up (39% vs. 50%, p = 0.45). Neither features of heart failure, nor those of arrhythmias showed differences between the groups, but parameters of quality of life and functional capacity proved to be favourable in Senning-operated patients. Conclusions: There is no significant difference in mortality and morbidity of patients with transposition of the great arteries following Mustard- and Senning-operations. Regarding to long-term follow-up quality of life and functional capacity of Senning-operated patients were more favourable. Orv. Hetil., 2016, 157(3), 104–110.

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Early NT-proBNP and MR-proANP associated with QoL 1 year after acutely decompensated heart failure: secondary analysis from the MOLITOR trial

Biomarkers in Medicine ◽

10.2217/bmm-2019-0083 ◽

2019 ◽

Vol 13 (17) ◽

pp. 1493-1507 ◽

Cited By ~ 3

Author(s):

Christine Zelenak ◽

Mira-Lynn Chavanon ◽

Elvis Tahirovic ◽

Tobias Daniel Trippel ◽

Verena Tscholl ◽

...

Keyword(s):

Quality Of Life ◽

Heart Failure ◽

Operating Characteristic ◽

Secondary Analysis ◽

Decompensated Heart Failure ◽

Unique Identifier ◽

Acutely Decompensated Heart Failure ◽

Long Term Prognosis

Aim: Heart failure negatively impacts quality of life (QoL), which in turn contributes to an adverse long-term prognosis. We aimed at identifying biomarker trajectories after an episode of acutely decompensated heart failure (ADHF) that differ between patients showing average versus impaired QoL 1 year later, thus allowing to predict impaired QoL. Methods: Biomarkers were repeatedly measured throughout the year in 104 ADHF patients. QoL was assessed at discharge and 1 year after ADHF. Logistic regression and receiver operating characteristic analyses were used to identify predictors of impaired QoL while controlling psychosocial confounders. Results: MR-proANP predicted impaired physical and mental QoL. NT-proBNP measurements were important predictors for poor physical QoL. Conclusion: MR-proANP and NT-proBNP predict poor QoL after an epidode of ADHF. The trial is registered at http://clinicaltrials.gov as MOLITOR (IMpact of therapy optimisation On the Level of biomarkers in paTients with Acute and Decompensated ChrOnic HeaRt Failure) with unique identifier: NCT01501981.

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