scholarly journals AN ATTEMPT TO UNDERSTAND THE CLINICAL APPROACH OF ADRAVYABHUTA CHIKITSA

2021 ◽  
Vol 9 (12) ◽  
pp. 3021-3025
Author(s):  
Shridharaiah M.H ◽  
Joshi P.V

Chikitsa (Treatment protocols) is Pravrutti (effort) made by Gunayukta Chikitsa Chatuspada (Physician, nurse, medications and patient) to bring back Dhatu Samyata (Healthy state) whenever there is Dhatu Vaikruti (Disease state). In Ayurvedic text, we got an explanation of many types of Chikitsa for different Vyadhis (Disease) or in different Avastha (Stages) of the Vyadhi. Among all these Chikitsa, we use Dravyabhuta Chikitsa (Dimensional things) like all medication including shodhana (Purification) and shamana (Pacification) broadly but the use of the Adravyabhuta Chikitsa (Non-dimensional) is very limited. Adravyabhuta is a type of Chikitsa that is classified based on the swarupa (Shape), these Adravyabhutas Chikitsa specially deals with non - dimensional things. This review article is explaining about concept and types of Adravyabhuta Chikitsa with classical examples which our Acharyas explained in Samhitas. Keywords: Chikitsa, Dravyabhuta, Adravyabhuta, Murta Bhava, Amurtha Bhava, Samavayi Karana.

2020 ◽  
Author(s):  
Norihiro Okada ◽  
Kenshiro Oshima ◽  
Yuki Iwasaki ◽  
Akiko Maruko ◽  
Erica Iioka ◽  
...  

AbstractIntron retention (IR) is an important regulatory mechanism that affects gene expression and protein functions. Using klotho mice as a model, we proposed that retained introns are an excellent marker for the pre-disease state. Surprisingly, among widespread retained introns that accumulated during aging in the liver, a subset was recovered to the normal state by a Japanese traditional herbal medicine. IR-recovered genes fell into two categories: (1) those involved in the spliceosome and (2) those involved in liver-specific metabolism. By integrating data for splicing patterns, transcriptomes, and metabolomes, we hypothesize that this medicine-related IR recovery under the pre-disease state reflects the actual recovery of liver-specific function to the healthy state. Accordingly, the study provides proof-of-concept evidence related to the ancient Chinese statement proposing the medicine’s usefulness for treating the pre-disease state. This approach lays out a method for elucidating unknown molecular mechanisms of an herbal medicine with multiple ingredients.


2021 ◽  
Vol 16 (3) ◽  
pp. 6-15
Author(s):  
Meenal Mavinkurve ◽  
Azriyanti Anuar Zaini ◽  
Muhammad Yazid Jalaludin

Stunting is a common phenomenon in Malaysian children. Optimising outcomes for children with growth disorders rests on early recognition and prompt referral. In this context, a framework for the clinical approach can help to guide appropriate growth assessment and referral. This review article aims to provide family medicine specialists with such a framework whilst raising awareness about the shortcomings of the existing growth monitoring system in Malaysia. It also invites readers to consider additional measures that could further optimise this system.


Author(s):  
Dr. Mohit Kumar ◽  
Dr. Sanjay Kumar Agri

In Ayurveda, there are three basic blocks upon which the human body stands, these are Dosha, Dhatu and Mala. Dhatus are the main which perform the function of holding together the bodily elements. There are seven Dhatu in person; these are Rasa, Rakta, Mamsa, Meda, Asthi, Majja and Shukra. As Mamsa Dhatu is very important component of our body and its Moola Sthana are Twacha and Snayu. Mamsa is one of the seven constructive build icons of body namely Dhatus. It is widely accepted by all the Ayurvedic scholars who named it as Pishit, Taras, Palal, Raktateja, Medaskruta, Kravyam, Aamisha and so on. It helps in formation of Mamsa Dhatu in the body with its principle site in body as muscles, tendons and skin. According to Ayurveda, there are seven Dhatu in person; these are Rasa, Rakta, Mamsa, Meda, Asthi, Majja and Shukra. These Dhatu are defined as per their function. These are important for healthy state of the body. Mamsa Dhatu is third one in the sequence of seven Dhatu.


Author(s):  
Jyoti M. Ganer ◽  
Umapati C. Baragi

Women have special dietary needs during each stage of her lives, including adolescence, pregnancy, breast feeding and menopause. During pregnancy the mother’s nutrition bears a great impact on the foetus’s growth and its future. Ayurveda lays great emphasis on ensuring holistic nutrition. A combination of Ahara (diet), Vihara (regimen), Vichara (emotions/thoughts) and Aushadha (medications) have been given great significance in Ayurveda in antenatal care called as Garbhini Paricharya (Antenatal care). Diet comprises the most important component of Garbhini Paricharya. Ayurveda advises congenital diet and regimen throughout the pregnancy. It also stresses on the healthy state of mind and body to beget healthy progeny. Milk and ghee stand out as the most common in the pregnant diet that Ayurveda advises. The idea of this is to provide optimum amount of protein and fat to the body. In addition, it provides right amount of calcium and vitamins for the pregnant mother helping in sustaining a comfortable lactation. In this review article a designed protocol of the month wise diet advised by various ancient Ayurvedic physicians, which can be modified according to the age, season, place, constitution and the digestive fire of the pregnant woman has been presented.


Rheumatology ◽  
2020 ◽  
Vol 59 (Supplement_5) ◽  
pp. v4-v11
Author(s):  
Martin Aringer ◽  
Sindhu R Johnson

Abstract The EULAR/ACR 2019 classification criteria for SLE constitute a current and optimized clinical approach to SLE classification. Classification is still not based on molecular approaches and the results from large studies using polyomics may be interpreted as demonstrating the relevance of the genetic and environmental background rather than splitting SLE into several entities. In fact, an association study within the EULAR/ACR classification criteria project found associations between manifestations only within organ domains. This independency of various organ manifestations argues for SLE as one disease entity. The current review article will therefore concentrate on the clinical and immunological manifestations of SLE and on what we have already learned in this century. Moreover, the structure and essential rules of the EULAR/ACR 2019 classification criteria will be discussed. While classification and diagnosis are distinct concepts, which have to remain clearly separated, information derived from the process towards the classification criteria is also useful for diagnostic purposes. Therefore this article also tries to delineate what classification can teach us for diagnosis, covering a wide variety of SLE manifestations.


2021 ◽  
Vol 11 (4-S) ◽  
pp. 236-241
Author(s):  
Gayatri Suresh K P ◽  
Thabit Ahmed ◽  
Mohamed Abdelgadir Mohammed Saeed ◽  
Jereish Varghese Daivamthadathil ◽  
Anandhu Jayan ◽  
...  

On 31 December 2019, pneumonia of unknown cause was detected in Wuhan, China, and was first reported to the WHO Country Office in China. On 30 January 2020, the outbreak was declared a Public Health Emergency of International Concern. 1 It was an outbreak of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infection that occurred in Wuhan, Hubei Province, China and got spread across China and beyond. WHO officially named the disease - Corona virus Disease 2019 (COVID-19) on February 12, 2020. 2 It has been spreading worldwide for a period of atleast a year & half 3 This review article addresses the current scenario caused by the SARS- Co V along with the treatment protocols and ongoing vaccines. Keywords: Corona virus,COVID-19, m RNA, current therapy, vaccines, clinical symptoms, review


2021 ◽  
Vol 7 (2) ◽  
pp. 1-15
Author(s):  
Kamal Alhallak ◽  

Light-based therapies, including laser, have evolved over the last decades in the dermatology and cosmetic fields. Practitioners should have a deep understanding of the mechanism of action and the effect of different laser parameters on treatments outcomes and safety profiles. Moreover, practitioners would not be able to improve the existing laser treatment protocols or develop new ones without understanding the light fundamentals and different laser-skin interactions. This review article attempts to bridge the theoretical concepts of laser and skin anatomy with the practical applications of light-based treatments.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 723-729
Author(s):  
Akshata Jaiswal ◽  
Swapnil Borage ◽  
Priyanka Shelotkar

The Corona Virus COVID-19 pandemic is the defining global health crisis emerging these days and the most significant challenge faced since World War Two. Corona Virus disease 2019 (COVID-19) is defined as an illness caused by a novel Corona Virus now called severe acute respiratory syndrome Corona Virus 2 (SARS-CoV-2), which was first identified due to outbreak of respiratory illness cases in Wuhan City, China. The most common symptoms include dry cough, fever and tiredness. Some may also develop aches and pains, nasal congestion, runny nose, sore throat or diarrhoea. There are no drugs or other therapeutics approved by the US Food and Drug Administration to prevent or treat COVID-19. Both ancient, as well as modern therapeutic procedures, can be adopted for COVID -19. Current advanced clinical management includes infection prevention and control measures and supportive care, including supplemental oxygen and mechanical ventilator support depending upon the condition. On the other hand, Ayurveda is equipped with a variety of treatment protocols including Dincharya (daily regime), Rutucharya (seasonal regime), Pranayama (Breathing exercise), and various Panchakarma (Purification) procedures.


Author(s):  
Stefano Ciaurelli ◽  
Caterina Origlia ◽  
Ariela Adamo ◽  
Silvia Giannattasio ◽  
Michael González ◽  
...  

Nutrigenetics concerns individual differences in the reaction to food based on the genetic factors. Nutrigenomics analyses direct influences of nutrients on gene expression. Both terms are explained in our review article. Nutrigenetics and nutrigenomics require a deep understanding of nutrition, genetics and biochemistry and of new ‘omic’ technologies. It is often difficult to appreciate their relevance in the practice of preventive approaches for optimizing health, delaying onset of disease and diminishing its severity. This paper represents a review about the current research on Nutrigenomics and Nutrigenetics, and provide scientific data for a new integrated clinical approach.


2020 ◽  
Vol 9 (2) ◽  
pp. 156
Author(s):  
Jihan Audini Karim

Prostate cancer is a noncutaneous malignancy in men, a heterogeneous disease with varying clinical outcomes. The modern clinical approach to prostate cancer emphasizes the need for treatment to avoid overdiagnosis and overtreatment. Advances in understanding of the pathogenesis of prostate cancer, coupled with technological innovations, have facilitated the development and validation of a number of molecular biomarkers, representing a variety of tested macromolecules from a wide variety of patient samples, to aid clinical management of prostate cancer, including early detection, diagnosis, prognostication, and selection. targeted therapy. Prostate cancer is asymptomatic in the early stages of the disease, there are various clinical-pathological signs and disease progression, and is characterized mostly by indolent cancer types. Therefore, it is imperative to develop individualized approaches for early detection, disease stratification (indolent vs. aggressive) and prediction of treatment response for prostate cancer. This article is a review article in which researchers review the current state of use of genomic biomarkers for early detection of prostate cancer, demonstrating the function of molecular biomarkers in clinical practice. The result of this review article is that the available genomic and proteomic tests can increase the predictive value of the PCa risk classification system based on clinical variables.


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