scholarly journals A Review on the Novel Corona Virus with International and Indian Perspective

2021 ◽  
Vol 11 (4-S) ◽  
pp. 236-241
Author(s):  
Gayatri Suresh K P ◽  
Thabit Ahmed ◽  
Mohamed Abdelgadir Mohammed Saeed ◽  
Jereish Varghese Daivamthadathil ◽  
Anandhu Jayan ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Virus Disease ◽  
Review Article ◽  
Current Therapy ◽  
The Novel ◽  
Treatment Protocols ◽  
Corona Virus ◽  
Current Scenario ◽  
Indian Perspective ◽  
Country Office

On 31 December 2019, pneumonia of unknown cause was detected in Wuhan, China, and was first reported to the WHO Country Office in China. On 30 January 2020, the outbreak was declared a Public Health Emergency of International Concern. 1 It was an outbreak of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infection that occurred in Wuhan, Hubei Province, China and got spread across China and beyond. WHO officially named the disease - Corona virus Disease 2019 (COVID-19) on February 12, 2020. 2 It has been spreading worldwide for a period of atleast a year & half 3 This review article addresses the current scenario caused by the SARS- Co V along with the treatment protocols and ongoing vaccines. Keywords: Corona virus,COVID-19, m RNA, current therapy, vaccines, clinical symptoms, review

scholarly journals Mastoid surgery: a high-risk aerosol generating surgical procedure in COVID-19 pandemic

2020 ◽  
Vol 6 (10) ◽  
pp. 1941
Author(s):  
Santosh Kumar Swain ◽  
Rohit Agrawala
Keyword(s):  
Medical Literature ◽  
Virus Disease ◽  
Review Article ◽  
The Novel ◽  
Personal Protection ◽  
Personal Protection Equipment ◽  
Team Members ◽  
Corona Virus ◽  
Unknown Status ◽  
Mastoid Surgery

<p class="abstract">Corona virus disease 2019 (COVID-19) is highly contagious disease occurred by the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) which spreads human to human through respiratory secretions. It was declared as public health emergency all over the world. There is lack of data in relation to the otologic or mastoid surgery during COVID-19 pandemic. Aerosolization of the novel corona virus SARS-CoV-2 is associated with middle ear and mastoid surgery. So, the safety precautions are important parts in this present pandemic time for preventing transmission of the infections to the surgeon and team members of the surgery. Preoperative screening for COVID-19 is must for safety of the surgeon and team members. The mastoid surgery on the positive, suspected or unknown status for COVID-19 patients need protection with adequate Personal protection equipment (PPE) such as disposable cap, N95 respirator and sealed eye protection or Powered air-purifying respirator (PAPR), disposable gown and gloves. In the mastoid surgery, there is scarcity of the medical literature related to the transmission of the novel corona virus SARS-CoV-2and its prevention during present COVID-19 pandemic. So, the aim of this review article is to increase awareness among the otolaryngologists for preventing the viral exposure during the mastoid surgery.</p>

Clinical cases of eculizumab use as a part of complex therapy in patients with severe COVID-19.

2021 ◽  
Author(s):  
Р.А. Майер ◽  
Б.А. Бакиров ◽  
А.А. Набиева ◽  
Д.А. Кудлай
Keyword(s):  
Virus Disease ◽  
Membrane Attack Complex ◽  
Lung Ventilation ◽  
Blood Analysis ◽  
The Novel ◽  
Reactive Protein ◽  
Corona Virus ◽  
Complex Therapy ◽  
Novel Coronavirus ◽  
Clinical Cases

Введение. В последние 2 года серьезной проблемой для всего мирового сообщества стало распространение новой коронавирусной (CoV) инфекции COVID-19 (COrona VIrus Disease-2019). Ввиду сложившихся событий в лечении COVID-19 активно стали применяться новые молекулы и уже зарегистрированные лекарственные препараты, доказавшие свою эффективность при других заболеваниях. Цель исследования: оценить эффективность применения препарата экулизумаб у пациентов с тяжелой формой течения COVID-19. Материалы и методы. Проанализированы 3 клинических случая применения препарата экулизумаб в составе комплексной терапии у пациентов с тяжелой формой течения COVID-19. Для оценки эффективности лечения проводился мониторинг основных клинико-лабораторных показателей, а также показателей, характеризующих воспалительный процесс при коронавирусной инфекции: общий анализ крови, биохимический анализ крови, проанализированы уровни таких показателей как ферритин, С-реактивный белок, интерлейкин-6, лактатдегидрогеназа и мембраноатакующий комплекс. Результаты. На фоне проводимой терапии выявлено снижение концентрации основных маркеров воспаления относительно исходных значений. Заключение. Комплексная терапия, включающая экулизумаб, облегчает течение заболевания, позволяет сократить длительность пребывания пациентов в отделении реанимации и интенсивной терапии, укорачивает срок их пребывания на искусственной вентиляции легких, тем самым снижая процент летальности. Background. In the past two years, the incidence of the novel coronavirus (CoV) infection COVID-19 (COrona Virus Disease-2019) has been a serious problem for the global community. Considering these circumstances, new molecules and already registered drugs that have proven their effectiveness in other diseases, began to be actively used in COVID-19 treatment. Objectives: to assess the effi cacy of eculizumab in patients with severe COVID-19. Patients/Methods. Three clinical cases of eculizumab use as a part of complex therapy in patients with severe COVID-19 have been analyzed. To assess the treatment efficacy, the main clinical and laboratory parameters and indicators of inflammatory process in coronavirus infection were monitored (clinical blood analysis, biochemical blood test, levels of ferritin, C-reactive protein, interleukin-6, lactate dehydrogenase and membrane attack complex). Results. Under the therapy we found the reduction of concentration of the main inflammation markers relative to the initial values. Conclusions. Complex therapy with eculizumab facilitates the course of the disease, reduces the stay duration of patients in the intensive care unit, shortens the period of artificial lung ventilation, thereby reducing the mortality rate.

scholarly journals To Evaluate Fear and Assess Practice Modification among Dentist against COVID-19 in India – A Questionnaire Based Survey

2021 ◽  
pp. 16-23
Author(s):  
Anil Ingole ◽  
Jayashree Sajjanar ◽  
Jaykumar Gade ◽  
Minal Soni ◽  
Karan Jaiswal ◽  
...  
Keyword(s):  
Direct Contact ◽  
Virus Disease ◽  
Central India ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Corona Virus ◽  
Dental Procedures ◽  
Dental Practitioners ◽  
Current Scenario ◽  
Fear And Anxiety

Introduction: This highly infective new virus, named Severe Acute Respiratory Syndrome-Coronavirus-2 (Sars-CoV-2), is a corona virus responsible of an acute respiratory syndrome, often asymptomatic but potentially lethal, named Corona Virus Disease 19 (COVID-19). Airborne and direct contact contamination is a major infection pathway of Sars-CoV-2. SARS-CoV-2 transmission during dental procedures can therefore happen through the inhalation of aerosol/droplets from infected individuals or direct contact with mucous membranes, oral fluids, and contaminated instruments and surfaces .Therefore, dentists have a high risk of getting infected from patients and potentially spreading it to their peers, families, and other patients. Aim: To evaluate fear and assess practice modification among dentist against COVID-19 in India Materials and Methods: In this cross-sectional study a total of 260 general dental practitioners, postgraduates and graduates across Central India, who were registered under the Dental Council of India, were included in the survey. A questionnaire consisting of 22 Questions with regard to COVID -19 fear and practice modification was designed and the questionnaire was circulated through a web designed program. The responses were collected, and data were analyzed descriptively using SPSS Statistics for Windows version 27.0. Results: There is a description of the fear and anxiety levels of dental care professionals towards COVID-19; 83.85% of participants were afraid of getting infected with COVID-19 from either a patient or a co-worker. While treating a coughing or a patient suspected to be infected with COVID-19, 90% were anxious. In terms of using personal protection, 63.85% believed that a surgical mask is not enough to prevent cross-infection of COVID-19. In comparison, 93.08% favored the use of N-95 masks for routine dental procedures during the current outbreak. Although the majority 91.15% recommended routine universal precautions of infection control. Conclusion: Overall, this study sheds light on the association of COVID-19 factors and fear and anxiety elevated among dentists during working in this pandemic. Covid-19 spread all over world and is worsening day by day. On current scenario several dental practices have either modified their services according to recommended guidelines to emergency treatment only, or closed down practices for an uncertain period.

scholarly journals COVID-19: A Critical Review on Viral Biochemistry, Environmental Transmission, Therapeutics and Safety Measures

2020 ◽  
Vol 1 (6) ◽  
Author(s):  
Roshni Kumari ◽  
Kumari Pragati Nanda ◽  
Hena Firdaus ◽  
Soumen Dey
Keyword(s):  
Specific Treatment ◽  
Scattered Data ◽  
Review Article ◽  
World Health ◽  
The Novel ◽  
Safety Measures ◽  
Current Scenario ◽  
Novel Coronavirus ◽  
Health Organization

The outbreak of coronavirus disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is declared pandemic by World Health Organization (WHO) keeping in view its infection rate and toxicity level. The entire world is struggling hard to survive the prevailing health emergency. The authors realise the urgent need of contributing an overview of the present scenario to the researchers who are breathlessly trying to combat this pandemic situation. This review aimed at binding all the scattered data and research available till now on COVID-19 disease starting from its origin to transmission and spread through environmental factors till treatment and the safety measures that should be implemented. This article would possibly help the readers by providing an outlook of current scenario on various perspectives of COVID-19 disease at a single glance. The types, origin and toxicity caused are discussed in brief. The role of contaminated aerosols (viral-laden smoke from tobacco, cigarettes), wastewater, fomites, human and faecal matter are important in spreading the novel coronavirus in the environment. There is no specific treatment till date but clinical trials and diagnosis on several known drugs are on-going. The precaution and safety measures could hopefully reduce number of infections and mortality. The number of infected cases confirmed till 2 August 2020 was 17660523 with 680894 deaths in the world. We tried in this review article to summarize the scattered data available on biochemistry of SARS-CoV-2, environmental spread of virus and the safety measures to combat COVID-19 pandemic.

scholarly journals A Review on Automatic Covid-19 Lung Infection Detection from Different Imaging Techniques

2021 ◽  
Vol 9 (VII) ◽  
pp. 3850-3856
Author(s):  
Sangeeta Singh
Keyword(s):  
World Health Organization ◽  
Virus Disease ◽  
Imaging Techniques ◽  
World Health ◽  
The Novel ◽  
Corona Virus ◽  
The World ◽  
Health Organization ◽  
High Level ◽  
Precision Rate

Corona Virus Disease-2019 commonly known as COVID-19 which has been defined by the Novel Corona Virus. It is a family of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) and was first detected during respiratory outbreak. It was first reported to the World Health Organization on December 31, 2019. On January 30, 2020, the World Health Organization declared the COVID-19 eruption a global health emergency. As of 27-May-2021 169,095,283 confirmed cases have been reported in the world and 2, 73, 67, 935 cases in India. It is required to identify the infection with high precision rate but there are lots of deficiency in the diagnosing system that may resulted false alarm rate. Initially it could be detected through throat saliva but now it can also be identified thought the impairment in lungs from computerized tomographical imaging technique. This paper reviewed various researches over COVID-19 diagnosis approach as well as the syndrome in respiratory organs. There are so many imaging techniques through which lungs impairments can be detected that may diagnose COVID-19 with high level of accuracy. CT scan image is the best alternative for diagnosing COVID-19.

scholarly journals COVID-19: The Pandemic Situation in the Context of India

2021 ◽  
pp. 456-463
Author(s):  
Daksh Hardaswani
Keyword(s):  
Virus Disease ◽  
The Novel ◽  
Physical And Mental Health ◽  
Health Crisis ◽  
Animal Virus ◽  
Therapeutic Drugs ◽  
Corona Virus ◽  
Hand Wash ◽  
The World ◽  
Financial Impacts

The novel corona virus disease (COVID-19) is a pandemic due to the global health crisis it has created in the world and greatest challenges that it has introduced in this 21ST century. COVID-19 is the the 5th pandemic which was first reported in Wuhan, China and gradually spread into the other parts of the world. This virus is a spillover of an animal virus and then also adapted the ability of transferring human to human. The virus is highly contagious due to rapid spread and constantly evolves in the human population.  COVID-19 pandemic is a lot more than just a health emergency, but it is also socio-economic because people are losing jobs and income. The COVID-19 disease affects physical and mental health due to isolation. Moreover, more and more countries are affecting the cases of COVID-19 which are rising very rapidly day by day. Therefore, every country needs to several actions which accelerates their safety health, balance between the protection of health, prevent economic and social disruption due to this pandemic. In the spirit of the solidarity, we all need to be contributing our self to protect this situation. However, every country is equally responsible for determining the measures to prevent or decrease the viral transmission. Government authorizes also trying to act for reduce disease’s trajectory and they focus on develop the vaccination and therapeutic drugs.  Aim: To find causes, symptoms, awareness, Prevention, and treatment of COVID-19. Conclusion: The world is going by the critical situation and that is COVID-19 pandemic which is originated due to corona virus. Shortness of breath, fever and dry cough are most common symptoms of the novel corona virus. COVID-19 is highly contagious, so we must keep safe distance from other people and wear a mast hand wash our hands frequently. As it were together can we overcome the interwoven wellbeing and social and financial impacts of the widespread and anticipate its acceleration into an extended compassionate and nourishment security catastrophe, with the potential misfortune of as of now accomplished advancement picks up. 

scholarly journals The First Case of Reactive Arthritis Associated with SARS-CoV-2-Infection in A 4-Year Old Child

2020 ◽  
Author(s):  
Stephanie Gabriele Werner ◽  
Hans-Eckhard Langer
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Reactive Arthritis ◽  
Virus Disease ◽  
The Novel ◽  
Case Presentation ◽  
Corona Virus ◽  
First Case ◽  
Novel Coronavirus ◽  
The Right

Abstract Background: The novel coronavirus SARS‐CoV‐2 (severe acute respiratory syndrome coronavirus 2) and its associated disease COVID‐19 (Corona Virus Disease 19) has become a worldwide pandemic since its first cases in December 2019 in Wuhan Province in China. In Germany the pandemic started in February 2020.Case presentation: A 4 year old boy was presented and suffered from pain in the right hip. Arthrosonography demonstrated a significant effusion in the involved joint. The extended history revealed a slight but long lasting cold before. Serological findings were inconspicuous except for positive ELISA (Enzyme-linked Immuno Sorbent Assay) - test for SARS-CoV-2. Conclusion: In conclusion we believe that we can report the first case of reactive arthritis associated with SARS-CoV-2 in children.

ANALYSIS OF THE MULTIDIMENSIONAL IMPACTS OF CORONA VIRUS DISEASE-2019 (COVID-19) PANDEMIC

2021 ◽  
Vol 9 (1) ◽  
pp. 96-105
Author(s):  
Imran ◽  
Saima Sarir ◽  
Mamoon Khan Khattak ◽  
Intikhab Alam ◽  
Seema Zubair
Keyword(s):  
Qualitative Research ◽  
Virus Disease ◽  
First Century ◽  
Future Research ◽  
Research Approach ◽  
The Novel ◽  
Travel And Tourism ◽  
Corona Virus ◽  
Depth Interview ◽  
Depth Interviews

Purpose of the study: The twenty-first century has witnessed numerous impacts of the novel Corona Virus Disease-2019 (Covid-19) pandemic in different walks of life across the globe. The present study was designed to get a societal response regarding the multifaceted impacts of the Covid-19 pandemic on the lives of the populace of the study locale. Methodology: The researchers selected a qualitative research approach for gaining in-depth insights on the issue at hand, wherein the data was collected from the potential participants through purposive sampling. The In-depth Interviews were conducted in district Swat which is one of the most affected districts from Covid-19. The In-depth Interview was used as a research instrument. The data was analyzed through thematic analysis. Main Findings: The study findings revealed that human lives are severely affected by the Covid-19 pandemic. The routine life cycle was badly affected, and people were confined to their houses. Like other parts of the world, different sectors like education, health, rituals, social interaction, travel, and tourism are desperately affected. Resultantly, it drastically raised the socio-cultural and economic (especially unemployment) unrest situation in the region. Apart from these consequences, due to the Pandemic scenario, various socio-cultural rituals, events, and activities were at a halt due to the imposition of social distancing measures. Applications of this study: The findings can be utilized/generalized in the normal course of life keeping in view the multidimensional impacts of the Covid-19 in the region. This study could be utilized for future research studies on the same issue. Novelty/Originality of this study: Besides, the study has immense significance, such studies are novel in the region with such a distinct perspective that covers various aspects of the impacts of Covid-19 using a qualitative research approach.  

scholarly journals Infodemic: How an Epidemic of Misinformation Could Lead to a High Number of the Novel Corona Virus Disease Cases in Uganda

2020 ◽  
Author(s):  
Betty K. Nannyonga ◽  
Rhoda K. Wanyenze ◽  
Pontiano Kaleebu ◽  
John M. Ssenkusu ◽  
Freddie Sengooba ◽  
...  
Keyword(s):  
Mathematical Model ◽  
Risk Communication ◽  
Virus Disease ◽  
Disease Spread ◽  
The Novel ◽  
Corona Virus

Misinformation during the COVID-19 outbreak has shaped our perception of the disease. Some people thinkthe disease is a bioweapon while others are convinced that it is a hoax. Heightened anxiety often producesfearful rumors, some of which are absurd while others seem plausible and are laced with some truths. But, how does misinformation affect disease spread? In this paper, we construct a mathematical model parameterized by Ugandan data, to study the effect of misinformation on community COVID-19 spread. The analysis shows that misinformation leads to high number of COVID-19 cases in a community, and the effect is highest in the rumour initiators and spreaders. This analysis underscores the importance of addressing misinformation in COVID risk communication.

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