scholarly journals AYURVEDIC MANAGEMENT OF STANAGRANTHI W.S.R TO FIBROADENOMA OF BREAST- A SINGLE CASE STUDY

2021 ◽  
Vol 9 (7) ◽  
pp. 1579-1587
Author(s):  
Nikitha Sirigere ◽  
Mahesh C.D ◽  
Pavitra Pavitra
Keyword(s):  
Single Case ◽  
Imaging Techniques ◽  
Psychological Impact ◽  
Hormonal Treatment ◽  
Modern Medicine ◽  
The Body ◽  
Systemic Review ◽  
Rational Approach ◽  
Distinct Area ◽  
Benign Tumours

The most common benign tumour of the female breast is fibroadenoma which is most common in young women under the age of 30. It accounts for approximately 25% of all lesions in asymptomatic women. It is a new growth formed of both fibrous and glandular tissues. This tumour is said to develop as the result of increased sensitivity of a focal area of the breast to estrogen. This tumour most commonly presented as a painless, slowly growing, solitary lump in the breast. In modern medicine after a systemic review of available conservative management like hormonal therapy, keeping in mind the side effect of hormonal treatment, surgeries like lumpectomy and mastectomy becomes the ideal option which also has its own physical and psychological impact on women’s life. A balanced and rational approach to the management of fibroadenoma of the breast needs to address the crucial questions about its associ- ation with breast cancer, which is ideally done by imaging techniques like mammography where fibroadenoma appears as a distinct area from other breast tissue, with smooth round edges and breast ultrasound where it is typi- cally seen as well-circumscribed, round to ovoid or macro lobulated mass or if necessary, a minimally invasive biopsy may be performed via a core needle biopsy i.e., FNAC. According to Ayurveda, this can be correlated toGranthi explained by many Acharya’s which develop due to abnormal vitiation of Dosha and Dushya. According to Acharya Charaka, Granthi can be equated with all types of small-sized glandular or nodular swelling in any part of the body due to benign tumours or cysts. There is no direct reference for Stana Granthi but Mamsaja Granthi occurs in Stana is having a close resemblance with fibroadenoma of the breast. So, in the present study, a patient with fibroadenoma was successfully treated by Ayurvedic management of tab Kanchanara guggulu and abyanga with Chandana bala lakshadi taila which got the significant result. Keywords: Abyanga, Estrogen, Fibroadenoma, Granthi, Mammography, Ultrasound.

EXPRESSION OF SOME IMMUNOLOGIC MARKERS FOR THE DIAGNOSIS OF SUSPECTED LYMPHOID LESIONS OF LYMPHOMA

2018 ◽  
Vol 8 (4) ◽  
pp. 28-33
Author(s):  
Mao Nguyen Van ◽  
Thao Le Thi Thu
Keyword(s):  
Correct Diagnosis ◽  
Tumour Cells ◽  
The Body ◽  
The Other ◽  
Cervical Region ◽  
Cross Sectional ◽  
Immunologic Markers ◽  
Microscopic Features ◽  
Poor Differentiation ◽  
Benign Tumours

Background: In practice it was difficult or impossible to have a correct diagnosis for the lymphoid proliferation lesions based on only H.E standard histopathology. In addition to histopathology, the application of immunohistochemistry was indispensable for the definitive diagnosis of the malignant or benign tumours and the origin of the tumour cells as well. Objectives: 1. To describe the gross and microscopic features of the suspected lesions of lymphoma; 2. To asses the expression of some immunologic markers for the diagnosis and classification of the suspected lesions of lymphoma. Materials and Method: Cross-sectional research on 81 patients diagnosed by histopathology as lymphomas or suspected lesions of lymphoma, following with immunohistopathology staining of 6 main markers including LCA, CD3, CD20, Bcl2, CD30 and AE1/3. Results: The most site was lymph node 58.1% which appeared at cervical region 72.3%, then the stomach 14.9% and small intestine 12.4%. The other sites in the body were met with lower frequency. Histopathologically, the most type of the lesions was atypical hyperplasia of the lymphoid tissue suspecting the lymphomas 49.4%, lymphomas 34.5%, the other diagnoses were lower including inflammation, poor differentiation carcinoam not excluding the lymphomas, lymphomas differentiating with poor differentiation carcinomas. Immunohistochemistry showed that, LCA, CD3, CD20, Bcl2, CD30 and AE1/3 were all positive depending on such type of tumours. The real lymphomas were 48/81 cases (59.3%), benign ones 35.8% and poor differentiated carcinomas 4.9%. Conclusion: Immunohistochemistry with 6 markers could help to diagnose correctly as benign or malignant lesions, classify and determine the origin of the tumour cells as lymphocytes or epithelial cells diagnosed by histopathology as lymphomas or suspected lesions of lymphomas. Key words: histopathology, immunohistochemistry, lymphomas, poor differentiated carcinomas, hyperplasia, atypicality

A Critical Review on Tamaka Shwasa (Bronchial Asthma) - An Ayurvedic View

2017 ◽  
Vol 2 (3) ◽  
Author(s):  
Sandip R. Baheti ◽  
Deepa Sharma ◽  
Saroj Devi ◽  
Amit Rai
Keyword(s):  
Bronchial Asthma ◽  
Inflammatory Disease ◽  
Critical Review ◽  
Modern Science ◽  
Modern Medicine ◽  
Chronic Inflammatory Disease ◽  
The Body ◽  
Natural Immunity ◽  
Shortness Of Breath ◽  
Asthma Symptoms

Difficulty in breathing or shortness of breath may be simply termed as Shwasa (Asthma), As per Ayurveda, Shwasa is mainly caused by the Vata and Kapha Doshas. Shwasa is broadly classified into five types in Maha Shwasa (Dyspnoea major), Urdhawa Shwasa (Expiratory Dyspnoea), Chinna Shwasa (Chyne-stroke respiration), Kshudra Shwasa (Dyspnoea minor), Tamaka Shwasa (Bronchial Asthma). In modern science Tamaka Shwasa can be correlated with Asthma, Asthma which is a chronic inflammatory disease of airway. In modern medicine there is no cure for Asthma, symptoms can typically be improved. In Ayurveda, Asthma can be effectively and safely manage the condition without inducing any drug dependency where Pachakarma procedures and use of internal medication detoxifies the body, provides nutrition and increases the elasticity of lung tissue it also develops natural immunity of the body thus decreasing episodic recurrence of the disease.

scholarly journals Psychological Consequences of the Delay in the Silent Mentor Programme During the COVID-19 Pandemic: Perspectives From Family Members of Silent Mentors

2021 ◽  
pp. 003022282110009
Author(s):  
Li Ping Wong ◽  
Sik Loo Tan ◽  
Haridah Alias ◽  
Thiam Eng Sia ◽  
Aik Saw
Keyword(s):  
Mental Health ◽  
Qualitative Interviews ◽  
Psychological Impact ◽  
Family Members ◽  
Well Being ◽  
The Body ◽  
Functional Health ◽  
Psychological Consequences ◽  
Negative Effect ◽  
Health And Well Being

The COVID-19 pandemic has put a hold on the Silent Mentor Programme (SMP); this pause has not only caused unprecedented challenges for the delivery of medical education but has forced changes in the programme ceremony sessions. We aimed to describe the psychological impact and experiences of family members of silent mentors during the COVID-19 pandemic using qualitative interviews. Many expressed feelings of remorse and unrest about the unprecedented delay of the SMP. The delay increased negative emotions particularly among some elderly family members; however, there was no prominent negative effect on their functional health and well-being. Several participants relayed the belief that the soul cannot rest until the body receives a proper burial while some worried about the deterioration of the physical condition of the mentors. In conclusion, findings provide insights into the importance of not overlooking the mental health implications of delaying the SMP in future outbreaks or crises.

Abstract P391: Marine N-3 Fatty Acids Reduce Atherosclerosis Cardiovascular Disease: A Systemic Review and Meta-analysis of Clinical Trials

Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Akira Sekikawa ◽  
Nobutake Hirooka ◽  
Abhishek Vishnu ◽  
Vashudha Ahuja ◽  
Emmanuel Sampene ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Fatty Acids ◽  
Clinical Trials ◽  
Randomized Clinical Trials ◽  
Imaging Techniques ◽  
Meta Analysis ◽  
Quantitative Information ◽  
Systemic Review ◽  
Cochrane Library ◽  
Cardiac Imaging Techniques

Introduction: Although marine n-3 fatty acids are believed to be cardioprotective through their anti-arrhythmic, anti-thrombotic, anti-atherogenic and other effects, results from recent meta-analyses of marine n-3 fatty acids on cardiovascular disease (CVD) are controversial. We performed a meta-analysis of marine n-3 fatty acids on CVD outcomes in randomized clinical trials (RCTs) to test the hypothesis that marine n-3 fatty acids are anti-atherogenic. We also tested the hypothesis that such benefit is dose-dependent. Methods: A systematic review of English language articles using PubMed, EMBASE and Cochrane Library through Aug 2012 was performed selecting RCTs evaluating the effect of marine n-3 fatty acids intake for 2 years or more on cardiovascular diseases, coronary disease, arteriosclerosis, cardiac imaging techniques, and carotid artery ultrasound. Descriptive and quantitative information was extracted. Odds ratios were calculated for cardiac event outcome. Correlation coefficients were obtained from studies of which outcome is intima-media thickness (IMT) and coronary lumen diameter (CD). We converted the estimates into a single effect size; the log odds ratio and its corresponding standard error. Results: Of 14,236 citations retrieved, 13 studies were selected, including studies reporting IMT (n=3) and CD (n=2) and major CVD events (n=8). Overall, marine n-3 fatty acids significantly reduced atherosclerotic CVD (RR 0.94: 95%CI 0.90 to 0.99, p<0.05). There was no evidence of heterogeneity (p=0.65) or publication bias (p=0.37, Begg’s test). A sub-analysis among 8 studies of major CVD events showed the similar results (RR 0.94: 95% CI 0.89 to 0.99, p<0.05). Another sub-analysis among 4 studies excluding sudden cardiac death as an outcome showed RR of 0.91 (95% CI 0.82 to 1.02, p=0.097). A meta-regression analysis shows that dose of marine n-3 fatty acids was inversely associated with CVD outcome, although the association was not statistically significant (p=0.06). Conclusions: The result of our meta-analysis supports a modest anti-atherogenic effect of marine n-3 fatty acids. This benefit may be proportional to the amount of marine n-3 fatty acids consumed.

scholarly journals Usnic Acid, a Natural Antimicrobial Agent Able To Inhibit Bacterial Biofilm Formation on Polymer Surfaces

2004 ◽  
Vol 48 (11) ◽  
pp. 4360-4365 ◽  
Author(s):  
I. Francolini ◽  
P. Norris ◽  
A. Piozzi ◽  
G. Donelli ◽  
P. Stoodley
Keyword(s):  
Biofilm Formation ◽  
Usnic Acid ◽  
Modern Medicine ◽  
The Body ◽  
Bacterial Biofilm ◽  
Polymer Surfaces ◽  
Gram Positive Bacteria ◽  
The Status ◽  
Bacteria And Fungi ◽  
Systemic Infections

ABSTRACT In modern medicine, artificial devices are used for repair or replacement of damaged parts of the body, delivery of drugs, and monitoring the status of critically ill patients. However, artificial surfaces are often susceptible to colonization by bacteria and fungi. Once microorganisms have adhered to the surface, they can form biofilms, resulting in highly resistant local or systemic infections. At this time, the evidence suggests that (+)-usnic acid, a secondary lichen metabolite, possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium. Since lichens are surface-attached communities that produce antibiotics, including usnic acid, to protect themselves from colonization by other bacteria, we hypothesized that the mode of action of usnic acid may be utilized in the control of medical biofilms. We loaded (+)-usnic acid into modified polyurethane and quantitatively assessed the capacity of (+)-usnic acid to control biofilm formation by either S. aureus or Pseudomonas aeruginosa under laminar flow conditions by using image analysis. (+)-Usnic acid-loaded polymers did not inhibit the initial attachment of S. aureus cells, but killing the attached cells resulted in the inhibition of biofilm. Interestingly, although P. aeruginosa biofilms did form on the surface of (+)-usnic acid-loaded polymer, the morphology of the biofilm was altered, possibly indicating that (+)-usnic acid interfered with signaling pathways.

scholarly journals Skin Darkening in COVID-19 Patients: Case Series of Eight Patients in a Hemodialysis Unit.

2021 ◽  
Vol 4 (03) ◽  
Author(s):  
Habib Ullah Rind ◽  
Nadia Iftikhar ◽  
Fazal ur Rehman ◽  
Abdul Kareem Zarkoon ◽  
Syed Mohkam ◽  
...  
Keyword(s):  
Dialysis Patient ◽  
Single Case ◽  
Case Series ◽  
The Body ◽  
Pressure Sores ◽  
Cutaneous Manifestations ◽  
Mortality And Morbidity ◽  
Skin Manifestations ◽  
Hemodialysis Unit ◽  
Type Pressure

The Pandemic of COVID-19 has grasped the whole world and changed dramatically, together with our social, occupational and personal life with high mortality and morbidity with other consequences since December 2019 started from Wuhan and then declared pandemic in March. It has been observed to involve every organ of the body including skin. Various skin manifestations, but most cases reported were like urticarial rash, xanthemas,  chickenpox-like vesicle, vasculitidic type, pressure sores, contact dermatitis and a single case was reported in china with skin darkening. The COVID-19 and cutaneous manifestations are recognized by physicians and dermatologist treating COVID-19. We have observed around eight cases of COVID -19 who had skin darkening in our center Baluchistan Institute of Nephrology and Urology Quetta, among these included were six dialysis technicians one chronic maintenance dialysis patient and a physician. We present the representative cases and discuss the skin manifestations of COVID-19.

scholarly journals The Peculiarities of Civil-Legal Regulation of Transplantation in Ukraine and Europe

2018 ◽  
Vol 8 (1) ◽  
pp. 33-48
Author(s):  
Alla Herts
Keyword(s):  
Treatment Process ◽  
Developed Countries ◽  
Legal Regulation ◽  
Modern Medicine ◽  
The Body ◽  
Accessibility Of Health Services ◽  
Surgical Field ◽  
Processed Form ◽  
The Cost ◽  
Cadaveric Transplantation

Abstract In modern realities the issue of the quality and accessibility of health services, the cost of medicines, examinations and treatment in general is being increasingly frequently discussed. The attention is focused on such a narrow surgical field as transplantation, because in Ukraine thousands of patients are waiting in line for organ transplantation and very few operations are performed. The main, most secure and common type of transplantation is the transplantation of organs and tissues from a deceased person, the dead body. Cadaveric transplantation, which is used in most developed countries, is hardly carried out in Ukraine. This is due to the fact that the current regulatory base of Ukraine in the field of transplantation does not fully meet the needs of modern medicine and has many gaps. The aim of donation is a future transplantation (including and in cases of blood transfusion and reproductive cells use). The parts (tissues, organs, their parts, individual cells) extracted (separated) from the body in the process of donation can be used generally in the treatment process in a processed form (blood plasma) or in the original state (fertilized reproductive cells). The detailed analysis of the provisions of the national legal system makes it possible to conclude that, despite the absence of direct regulation of relations concerning organ donation and transplantation as material relations, the legal regulations provide the fundamental provisions, which determine their material nature, and therefore offer opportunities for agreementbased regulation. In our opinion, one of the essential legal means of ensuring the rights of participants in the relations of donation and transplantation can be their agreement-based regulation. The peculiarities of civil-legal regulation of transplantation in Ukraine and Europe are simultaneously analysed; and the grounds of its legitimacy are defined.

scholarly journals AN AYURVEDIC MANAGEMENT OF SUBCLINICAL HYPOTHYROIDISM - A CASE REPORT

2018 ◽  
Vol 6 (5) ◽  
pp. 481-486
Author(s):  
Dnyaneshwar Kantaram Jadhav
Keyword(s):  
Internal Medicine ◽  
Case Report ◽  
Weight Gain ◽  
Subclinical Hypothyroidism ◽  
Single Case ◽  
Excellent Result ◽  
Modern Medicine ◽  
Single Case Study ◽  
Ayurvedic Treatment

Ayurved is science of life. Its guide human being for living on preventive & curative both aspect. Its ancient knowledge which is still stand truth to time. There are many diseases which is not mentioned directly in Ayurveda texts is called as Anukta vikar. Subclinical hypothyroidism is one of such disease. Such disease specifically mentioned but its line of treatment described very well. The present case is 28 year old male patient was suffering from Bhaar vrudhi (weight gain) from last 2.5 years while symptoms like Drubalya (fatigue), Sheet prachiti (feeling excessive cold), Bhrama (vertigo),  Shwasakashtata (dyspnoea after walking), Katishool (backache) since last 2 years. Patient on modern medicine still he doesn’t get any satisfy relief, at the end patient decide to take Ayurvedic treatment only. For treatment patient was came to Nakshatra Ayurved Panchkarma clinic & Research center, Mumbai. Ayurvedic management include internal medicine, Rukshaya bashpa peti sweda. After 1.5 month patient got Excellent Result. All symptoms disappear, weight reduces up-to 4 kg, TSH level comes from 7.71 to 3.23. This is single case study, will Collect data of more cases for further Research.

scholarly journals Bioactive Phenolic Compounds from Indian Medicinal Plants for Pharmaceutical and Medical Aspects

2021 ◽  
Author(s):  
Bhanu Kumar ◽  
Ankita Misra ◽  
Sharad Srivastava
Keyword(s):  
Phenolic Compounds ◽  
Medicinal Plants ◽  
Modern Medicine ◽  
The Body ◽  
Human Welfare ◽  
Therapeutic Benefits ◽  
Plant Constituents ◽  
Health And Disease ◽  
Tools And Techniques ◽  
Indian Medicinal Plants

Ayurveda is an age old system of medicine which utilizes thousands of medicinal plants, rich in secondary metabolites for their therapeutic benefits and phenolic compounds are important one. Plant phenolic compounds are one of the major group of phytomolecules having tremendous therapeutic and nutraceutical potential. Indian medicinal plants like Emblica, Terminalia spp., Withania, Tinospora etc. are some of the potential source of bioactive phenolics and had been used from ages in various Ayurvedic formulations and were scientifically validated too. In this contribution, a brief account of some common Indian medicinal plants rich in bioactive phenolics are summarized along with their therapeutic action on human health and disease. The vast array of phenolics in these plants makes them a suitable candidate for modern medicine, nutraceutical supplements, immuno-modulatory formulations etc. With the advent of modern separation tools and techniques, it is now possible to identify, isolate and purify desired phytoconstituents from plant extracts. This further opens the avenues of utilizing medicinal plants or plant constituents/metabolites as super food for strengthening the body and maintaining the healthy work-life balance. The need of the hour is to identify therapeutically potential phenolics rich plants and development of herbal formulations for human welfare.

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