scholarly journals Bioactive Phenolic Compounds from Indian Medicinal Plants for Pharmaceutical and Medical Aspects

2021 ◽  
Author(s):  
Bhanu Kumar ◽  
Ankita Misra ◽  
Sharad Srivastava
Keyword(s):  
Phenolic Compounds ◽  
Medicinal Plants ◽  
Modern Medicine ◽  
The Body ◽  
Human Welfare ◽  
Therapeutic Benefits ◽  
Plant Constituents ◽  
Health And Disease ◽  
Tools And Techniques ◽  
Indian Medicinal Plants

Ayurveda is an age old system of medicine which utilizes thousands of medicinal plants, rich in secondary metabolites for their therapeutic benefits and phenolic compounds are important one. Plant phenolic compounds are one of the major group of phytomolecules having tremendous therapeutic and nutraceutical potential. Indian medicinal plants like Emblica, Terminalia spp., Withania, Tinospora etc. are some of the potential source of bioactive phenolics and had been used from ages in various Ayurvedic formulations and were scientifically validated too. In this contribution, a brief account of some common Indian medicinal plants rich in bioactive phenolics are summarized along with their therapeutic action on human health and disease. The vast array of phenolics in these plants makes them a suitable candidate for modern medicine, nutraceutical supplements, immuno-modulatory formulations etc. With the advent of modern separation tools and techniques, it is now possible to identify, isolate and purify desired phytoconstituents from plant extracts. This further opens the avenues of utilizing medicinal plants or plant constituents/metabolites as super food for strengthening the body and maintaining the healthy work-life balance. The need of the hour is to identify therapeutically potential phenolics rich plants and development of herbal formulations for human welfare.

Indian medicinal plants with antidiabetic potential: An overview

2021 ◽  
pp. 2328-2335
Author(s):  
Monika Sahu ◽  
Vinod Kumar ◽  
Veenu Joshi
Keyword(s):  
Diabetes Mellitus ◽  
Medicinal Plants ◽  
The Body ◽  
Therapeutic Drug ◽  
Major Health ◽  
Synthetic Drugs ◽  
Comprehensive Information ◽  
Chronic Disorders ◽  
The Rich ◽  
Indian Medicinal Plants

Diabetes Mellitus is the most prevalent metabolic disorder which has made it a major health threat worldwide. The available synthetic drugs for the cure of Diabetes mellitus are associated with high cost, various side effects and several limitations. Medicinal plants are the rich depots of the phytochemicals which can be useful for the treatment of chronic disorders. These plants are the better alternative to chemical drugs causing less or no harm to the body. Several plants are traditionally known for their antidiabetic properties but the detail investigation of their active molecules is required in order to be developed as therapeutic drug. Therefore, the present review aims to provide comprehensive information on various Indian medicinal plants, their constituents and mechanism of action for the cure of diabetes mellitus.

scholarly journals IMPORTANCE OF RASAVAHA STROTAS DUSHTI HETU AND AGNI CONCEPT IN PANDUROGA

2021 ◽  
Vol 9 (5) ◽  
pp. 1121-1125
Author(s):  
Sushil Haribhau Patil ◽  
Vaishali Milind Suryawanshi ◽  
Sangita Pramod Shende
Keyword(s):  
Disease Prevention ◽  
Basic Concept ◽  
Signs And Symptoms ◽  
Modern Medicine ◽  
The Body ◽  
Treatment Modalities ◽  
Prevention And Treatment ◽  
Health And Disease ◽  
Internal Transport ◽  
Better Than

Ayurveda is the science which mentioned various principles for prevention and treatment of disease. ‘Prevention is better than cure’ is the basic concept of Ayurveda. It is a science of life and a great heritage of India. Ayurveda provides various treatment modalities and principles for maintaining proper health. In Ayurveda various concepts are described which are unique in sense as well as having its meaningful knowledge. Among them concept of Strotas and Agni also are very important. Agni has bio-transformative activity in the body which maintain Swasthya. Dosha Samyata and Vishamata are depends upon the Agni. The internal transport system of the body is represented by strotas and has been given a place of fundamental importance in Ayurveda for health and disease. There are 13 types of Strotas according to Acharya Charaka and 11 types according to Sushruta. In any Vikara utpatti, there is vitiation of Dosha, Dhatu, Mala and also Strotas. Rasavaha strotas is the strotas that does the circulation of Dosha, Dhatu, Anna, Jala. Rasavaha Strotas dushti leads to Vikara formation includes Pandu. In Ayurveda, AcharyaCharaka in his classical treaties, under the heading ‘Pandu’ as mentioned a group of symptoms which very closely resembles with the signs and symptoms of Anaemia according to modern medicine. Keywords: Strotas, Agni, Rasavaha strotodushti Hetu, Panduroga.

scholarly journals The Therapeutic Potential of Breast Milk-Derived Extracellular Vesicles

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 745 ◽  
Author(s):  
Jeffrey D. Galley ◽  
Gail E. Besner
Keyword(s):  
Breast Milk ◽  
Extracellular Vesicles ◽  
Therapeutic Potential ◽  
Gastrointestinal Disease ◽  
The Body ◽  
Parent Cell ◽  
Therapeutic Effects ◽  
Human Breast Milk ◽  
Therapeutic Benefits ◽  
Health And Disease

In the past few decades, interest in the therapeutic benefits of exosomes and extracellular vesicles (EVs) has grown exponentially. Exosomes/EVs are small particles which are produced and exocytosed by cells throughout the body. They are loaded with active regulatory and stimulatory molecules from the parent cell including miRNAs and enzymes, making them prime targets in therapeutics and diagnostics. Breast milk, known for years to have beneficial health effects, contains a population of EVs which may mediate its therapeutic effects. This review offers an update on the therapeutic potential of exosomes/EVs in disease, with a focus on EVs present in human breast milk and their remedial effect in the gastrointestinal disease necrotizing enterocolitis. Additionally, the relationship between EV miRNAs, health, and disease will be examined, along with the potential for EVs and their miRNAs to be engineered for targeted treatments.

scholarly journals Inventarytation of medicinal plants as a self-medication by the Tolaki, Puundoho village, North Kolaka regency, Southeast Sulawesi

2021 ◽  
Vol 17 (1) ◽  
pp. 19-33
Author(s):  
Hasria Alang ◽  
◽  
Hastuti Hastuti ◽  
Muhammad Sri Yusal ◽  
Keyword(s):  
Herbal Medicine ◽  
Medicinal Plants ◽  
Traditional Medicine ◽  
Traditional Healers ◽  
Modern Medicine ◽  
The Body ◽  
Ethical Perspective ◽  
Self Medication ◽  
Traditional Medicines ◽  
The Road

Background: Traditional medicine knowledge is one of the local wisdoms and is passed down from generation to generation. Traditional medicine needs to be preserved in order to maintain the continuity of this knowledge; besides that, it requires a balance between modern medicine and herbal medicine. Herbal medicine is easy to obtain in the surrounding environment, at affordable prices and guarantees the safety of medicinal chemicals that are harmful to the body. The use of drugs for a long period of time is a habit that is harmful to the body organs because they contain certain chemical compounds that are not safe for human vital organs, so it is necessary to make an inventory effort by digging up information from traditional healers. This research is expected to make a significant contribution so that the role of herbal plants can be maintained and developed in the future. Objective: to inventory the plant species which useful as traditional medicines used by traditional healers of the Tolaki tribe in Puundoho village. Method: The method used in this research is a qualitative exploration, through an emic approach or a community and ethical perspective supported by scientific literature. The use of qualitative methods in this study is intended to describe people's knowledge Results: The interview results with three traditional healers (mbu'wai) in Puundoho village about plants that can be used as traditional medicines. It can be found on the side of the road, garden and yard. The part of the plant used is the whole plant or part of the plant such as roots, stems, or leaves. The method to blend it is boiled or mashed. The use of traditional medicines is applied orally or topically. Conclusion: The types of traditional medicinal plants used by the Tolaki tribe in Puundoho village can be obtained from yards, gardens, and roadsides including sidaguri, ciplukan, jeringan, bangle, purslane, bandotan, boborongan, turi, meniran, ­­­­banjar berrywit, mesoyi, ketepeng, guava, ginger, kencur, blechnum nails and ketepeng Keywords: Herbal medicine, inventarytation, medicinal plants, traditional medicine

Rheumatoid Arthritis: History, Stages, Epidemiology, Pathogenesis, Diagnosis and Treatment

2017 ◽  
Vol 9 (02) ◽  
Author(s):  
Abeer Fauzi Al-Rubaye ◽  
Mohanad Jawad Kadhim ◽  
Imad Hadi Hameed
Keyword(s):  
Rheumatoid Arthritis ◽  
Medicinal Plants ◽  
Systemic Disease ◽  
Modern Medicine ◽  
Whole Body ◽  
Internal Organs ◽  
Synthetic Drugs ◽  
Relieve Pain ◽  
Medicinal Treatment ◽  
Natural Drugs

The pharmacological mechanisms of the medicinal plants traditionally used for RA in Persian medicine are discussed in the current review. Further investigations are mandatory to focus on bioefficacy of these phytochemicals for finding novel natural drugs. Rheumatoid arthritis is chronic, progressive, disabling autoimmune disease characterized by systemic inflammation of joints, damaging cartilage and bone around the joints. It is a systemic disease which means that it can affect the whole body and internal organs such as lungs, heart and eyes. Although numbers of synthetic drugs are being used as standard treatment for rheumatoid arthritis but they have adverse effect that can compromise the therapeutic treatment. Unfortunately, there is still no effective known medicinal treatment that cures rheumatoid arthritis as the modern medicine can only treat the symptoms of this disease that means to relieve pain and inflammation of joints. It is possible to use the herbs and plants in various forms in order to relieve the pain and inflammation in the joints. There are so many medicinal plants that have shown anti rheumatoid arthritis properties. So the plants and plant product with significant advantages are used for the treatment of rheumatoid arthritis. The present review is focused on the medicinal plants having anti rheumatoid arthritis activity

In-vivo evaluation of lipid lowering ability of Chloris paraguaiensis extracts

2020 ◽  
Vol 7 (2) ◽  
pp. 21-24
Author(s):  
Pavani C H
Keyword(s):  
Medicinal Plants ◽  
Chemical Constituents ◽  
The Body ◽  
Lipid Lowering ◽  
Medical Systems ◽  
In Vivo Evaluation ◽  
Standard Drug ◽  
Anti Oxidant ◽  
And Control

Hyperlipidemia is the immediate results of the excessive fat intake in food. This results in the elevated levels of cholesterol and triglycerides in the blood. This leads to heart conditions like CAD, hypertension, congestive heart failure as risk factors which can be lethal. There are many drugs to treat and control the lipids levels in the body. These drugs are either designed to prevent LDL accumulation and VLDL synthesis. Some drugs also lower the elevated levels of saturated lipids in the body. But many drugs are known to cause side effects and adverse effects; therefore, alternatives to the drugs are the subjects for current investigations. Herbs and medicinal plants are used as treatment sources for many years. They have been used in the Indian medical systems like Ayurveda, Siddha etc. As the application of herbs in the treatment is growing, there is an urgent need for the establishment of Pharmacological reasoning and standardization of the activity of the medicinal plants. Chloris paraguaiensis Steud. is Poyaceae member that is called locally as Uppugaddi. Traditionally it is used to treat Rheumatism, Diabetes, fever and diarrhoea. The chemical constituents are known to have anti-oxidant properties and most of the anti-oxidants have anti-hyperlipidemic activity too. Since the plant has abundant flavonoid and phenol content, the current research focusses on the investigation of the anti-hyperlipidemic activity of the plant Chloris extracts. Extracts of Chloris at 200mg/kg showed a comparably similar anti hyperlipidemia activity to that of the standard drug. The extracts showed a dose based increase in the activity at 100 and 200mg/kg body weight.

CARBOHYDRATE PRODUCT FOR THERAPEUTIC AND PROPHYLACTIC PURPOSES

2020 ◽  
pp. 89-94
Author(s):  
Khvorova L.S. ◽  
Byzov V.A.
Keyword(s):  
Antioxidant Activity ◽  
Uric Acid ◽  
Phenolic Compounds ◽  
Mental Stress ◽  
The Body ◽  
Hot Water ◽  
Preventive Effect ◽  
Activity Inhibition ◽  
Medicinal Properties ◽  
Simple Carbohydrates

The article is devoted to the creation of a carbohydrate product with rosehip extract in the form of sweets (glucose Fudge) with a therapeutic and preventive effect aimed at restoring the body of people exposed to intense physical and mental stress and the effects of damaging environmental factors. As carbohydrates in the recipe, simple carbohydrates (glucose) and complex carbohydrates in the form of starch molasses containing (maltose, tri - Tetra - sugars, dextrins) are used. Glucose in the formulation is the main energy ingredient, sweetener and structure-forming component that gives the product a solid consistency due to crystallization. The medicinal effect of the product is provided by rosehip extract. Numerous published studies have established its vitamin, immunostimulating and antioxidant activity, inhibition of uric acid formation and obesity, which are associated with flavonoids, other phenolic compounds, and vitamins. The list of medicinal properties of rosehip extract shows the feasibility of using it in additional nutrition of people in order to prevent diseases. For the formulation of our sweets, the extraction of crushed rosehip fruits was carried out three times with hot water at a temperature of 65-700C, followed by concentration of the extract under vacuum to 25-30% SV. The resulting extract-concentrate was introduced into the formulation in a dosage of 5.5% SV per 100 g of SV glucose Fudge, which provided the necessary dosage for the product when used from 3 (for children) to 10 sweets a day (for adults) for the prevention of colds.

Determination of Lead Content in Red Colored Lipsticks from Mandalay Market by Flame Atomic Absorption Spectrophotometer

2018 ◽  
Vol 30 (3) ◽  
pp. 167-173
Keyword(s):  
Sampling Procedure ◽  
The Body ◽  
Lead Content ◽  
Social Psychological ◽  
Allowable Limit ◽  
Flame Atomic Absorption ◽  
Therapeutic Benefits ◽  
Flame Atomic Absorption Spectrophotometer ◽  
Exposure Levels

Red colored lipstick is the most widely used cosmetic product. Although lipstick gives a lot of social, psychological and therapeutic benefits, it may harm the consumers. Because some lipsticks contain a considerable amount of heavy metal especially lead. Lead is being used in lipstick mainly for the pigments required to obtain needed colors. Lead accumulates in the body over time and lead-containing lipstick applied several times a day, every day, combined with lead in water and other sources, could add up to significant exposure levels. Therefore, this study was aimed to determine lead content in red colored lipsticks from market. This study was laboratorybased, analytical study by using 25 lipstick samples. Red colored lipsticks were bought from Mandalay Market by random sampling procedure and they were completely coded to avoid the bias. Then, lead content in coded samples was determined by Flame AAS according to International Conference on Harmonization (ICH) guideline. Lead contents of 88% of the lipsticks samples were more than specified limit (20 ppm) of Food and Drug Administration, United States. All of them, lead content was highest in counterfeit lipsticks group. Among the tested lipstick samples, lipstick with lowest lead content was LE-RL 01 (15.74 ppm) and the lipstick with highest lead content was CF-RL 01(60.09 ppm). In conclusion, lead contents of red colored lipsticks (22 out of 25) from market samples were higher than allowable limit (20 ppm).

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