scholarly journals Herbal Drugs Used in Diabetes Mellitus

Author(s):  
Ankit Rana ◽  
Ramandeep Singh

Diabetes mellitus (DM) is the most common of the endocrine disorders. It is an important human ailment, afflicting many, from various walks of life in different countries. The prevalence of diabetes mellitus is expected to reach up to 4.4% in the world by 2030. Among all type of diabetes, type 2 diabetes is main complication. Currently available treatment option in modern medicine have several adverse effects. Therefore, there is a need to develop safe and effective treatment modalities for diabetes. Medicinal plants play an important role in the management of diabetes mellitus especially in developing countries where resources are meager. This article presents a review on some reported anti-diabetic medicinal plants

Author(s):  
Mulia Mayangsari

 Individuals who have a family history oftype 2 diabetes mellitus (DM) have a highrisk for type 2 diabetes. Type 2 diabetescan be prevented by improving modifiablerisk factors, supported by self-awareness,perceptions and attitudes of individualswho have a high family history of DM. Thisstudy used a qualitative phenomenologicaldesign. A Purposive Sampling techiniquewas applied to determine individuals whohad parents with type 2 diabetes. Nineindividuals participated in this study. AQualitative content analysis with Collaiziapproach used as a data analysis method.The main themes depicted individuals selfawareness,perceptions, & attitudes were:denials that diabetes caused by heredityfactors; misperception about diabetes;“traditional modalities” as a preventionmeasurement toward type 2 diabetes; andDM is perceived as a “threatening disease”.Further study is needed to examine indepth the themes that have been identifiedon the number of participants are morenumerous and varied.


2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Mustapha Zainab Abubakar ◽  
Kabiru Abdulsalam ◽  
Isah A. Yahaya

Diabetes mellitus (DM) and thyroid disease are the two most common endocrine disorders in the general population. Several Studies have shown that thyroid dysfunction is common in patients with DM, and thyroid dysfunction have been found to have a considerable impact on the glycaemic control and often increases the risk of development of long-term complications in patients with diabetes mellitus. This study determined the prevalence of thyroid dysfunction in patients with type 2 DM in Kano, North-Western Nigeria. The study was a descriptive cross-sectional study conducted on 250 participants made up of 130 patients with type 2 DM and 120 apparently healthy non-diabetic controls. Questionnaires were used to collect information on bio data, medical history, duration of diagnosis of diabetes and type of treatment. Also, blood samples of the participants were collected and analyzed for fasting plasma glucose, fT3, fT4, and TSH. The results were interpreted using American Thyroid Associations’ criteria and the data was analyzed using the statistical software package, STATA version 20. Two hundred and thirty-four (93.6%) of the participants were euthyroid while sixteen (6.4%) were found to have various forms of thyroid dysfunction. The prevalence of thyroid dysfunction was 10% and 2.5% among type 2 diabetics and controls respectively. Among the type 2 DM patients with thyroid dysfunction, 38.5% had hypothyroidism. Thyroid dysfunction was found to be commoner among type 2 DM patients than non-diabetic individuals with hypothyroidism being the commonest disorder.


Author(s):  
K. Nithesh Kumar ◽  
Sushma Katkuri ◽  
I. Ramyacharitha

Background: Type 2 diabetes mellitus is a chronic, debilitating disease characterized by insulin resistance, impaired insulin secretion and hyperglycemia. It represents more than 90% of total prevalence of diabetes in the world and is responsible for 9% of the global mortality corresponding to four million deaths per year. The objective of the study was to assess the prevalence of diabetes mellitus type-2 in a rural population of age 30 years and above.Methods: A community based cross sectional study carried out in population 30 years and above in rural area of Khammam district in Telangana during the study period from 1st January to 31st December 2015. A total of 910 persons aged 30 years or more were included in study.Results: Near about 74 (8.1%) were diagnosed as type -2 diabetes mellitus. The prevalence of DM was 16.22% in 30-40 years age group, 24.32% in 41-50 years age group, 43.34% in 51-60 years age group and 16.2% in 61-70 years age group which shows that DM increases with age and the association between age and prevalence of type 2 DM was found to be statistically significant.Conclusions: There is a need to increase awareness of type–2 diabetes mellitus in the general population. Health education should be given in terms of risk factors of diabetes. They should be made aware about early screening methods. 


2018 ◽  
pp. 36-39
Author(s):  
M.O. Pavlovska ◽  

The objective: was to compare the efficacy of complex methods of treating climacteric syndrome in patients with concomitant type 2 diabetes mellitus (DM) by analyzing hormonal parameters before and after complex therapy using antihomotoxicological drugs. Materials and methods. We examined 58 patients aged 45-55 years with a climacteric syndrome on the background of a 2-type diabetes mellitus. Women of the 1st group (n = 28) received only basic therapy according to the National Consensus for the management of patients in menopause with concomitant DM of type 2. Women of the 2nd group (n = 30) were treated with antihomotoxicological drugs against the background of basic therapy. Results. The proposed complexes positively influenced the hormonal state of patients, and also reduced the severity of climacteric syndrome and psychoemotional component. More effective was a complex that included antihomotoxicological agents, which is confirmed by the dynamics of hormonal parameters. Conclusion. From the clinical point of view, the obtained results give grounds to recommend these complexes for the correction of hormonal disorders in women with menopausal disorders on the background of type 2 diabetes mellitus. Key words: climacteric syndrome, diabetes type 2, base therapy, antihomotoxicological agents.


Author(s):  
Eric C. Westman ◽  
Emily Maguire ◽  
William S. Yancy

Obesity and type 2 diabetes mellitus (T2DM) have reached epidemic proportions worldwide. While characterized by chronic hyperglycemia, the underlying cause of T2DM is insulin resistance—most often related to an increase in abdominal adiposity caused by obesity. The goal of treatment of T2DM is to put the disease into remission by targeting the underlying insulin resistance. The observation that dietary carbohydrate is the major factor to cause glycosuria and hyperglycemia, has been known since the early days of modern medicine. As a result, low-carbohydrate, ketogenic diets were employed to treat obesity and diabetes in the nineteenth and early twentieth centuries. This chapter reviews the rationale and recent clinical research supporting the use of a low-carbohydrate, ketogenic diet in individuals with obesity and diabetes. For individuals affected by obesity-related T2DM, clinical studies have shown that carbohydrate restriction and weight loss can improve hyperglycemia, obesity, and T2DM.


2018 ◽  
Vol 215 ◽  
pp. 140-146 ◽  
Author(s):  
Rodrigo Rodrigues Franco ◽  
Danúbia da Silva Carvalho ◽  
Francyelle Borges Rosa de Moura ◽  
Allisson Benatti Justino ◽  
Heitor Cappato Guerra Silva ◽  
...  

2006 ◽  
Vol 96 (1) ◽  
pp. 67-72 ◽  
Author(s):  
David M. Kanuck ◽  
Thomas Zgonis ◽  
Gary Peter Jolly

Necrotizing fasciitis is a soft-tissue infection characterized by extensive necrosis of subcutaneous fat, neurovascular structures, and fascia. In general, fascial necrosis precedes muscle and skin involvement, hence its namesake. Initially, this uncommon and rapidly progressive disease process can present as a form of cellulitis or superficial abscess. However, the high morbidity and mortality rates associated with necrotizing fasciitis suggest a more serious, ominous condition. A delay in diagnosis can result in progressive advancement highlighted by widespread infection, multiple-organ involvement, and, ultimately, death. We present a case of limb salvage in a 52-year-old patient with type 2 diabetes mellitus and progressive fascial necrosis. A detailed review of the literature is presented, and current treatment modalities are described. Aggressive surgical debridement, comprehensive medical management of the sepsis and comorbidities, and timely closure of the resultant wound or wounds are essential for a successful outcome. (J Am Podiatr Med Assoc 96(1): 67–72, 2006)


2020 ◽  
Vol 10 (4) ◽  
pp. e34-e34
Author(s):  
Mahsa Mohammadi ◽  
Mohsen Rajabnia ◽  
Mohammad Saad Forghani ◽  
Khaled Rahmani ◽  
Mohammad Bahadoram

Introduction: Diabetic nephropathy (diabetic kidney disease) is one of the microvascular complications of diabetes mellitus. The human leukocyte antigen (HLA) is a group of genes that is related to autoimmune diseases, infections and inflammation. Studies regarding the association of type 2diabetes and HLA-II are negligible. Objectives: The aim of this study is to determinate association between diabetic nephropathy and HLA II-DQ1 in diabetes type 2 patients. Patients and Methods: In this study, 120 diabetes type 2 patients were divided into two groups of diabetic nephropathy (case group) and without diabetic nephropathy (control group). Blood samples were taken and DNA was isolated. Asymmetric polymerase chain reaction (PCR) was used to amplify the HLA II-DQ1 exon 2 and exon 3. PCR products were hybridized and labeled with probes on the chip. Determination of HLAII-DQ1 gene typing was conducted by scanning hybrid products and analyzed with PerkinElmer ScanArray software. Results: The results of chi-square test showed no significant difference between expression levels of HLA in the two groups (P<0.05). Conclusion: There was no significant difference between expression levels of HLA in two groups of patients. Various factors such as demographic characteristics, lifestyle, geographic region, and race are the factors influencing the relationship between diabetic nephropathy and DQ1-HLA II. Since this study is conducted in one region and one race and with limited population, it is suggested that future studies should be considered and the association between the mentioned variables with HLA should be considered.


Sign in / Sign up

Export Citation Format

Share Document