scholarly journals COMPARATIVE STUDY OF EFFECT OF CHAIN YOGIC EXERCISE (YOGASANA) AND YOGIC THERAPY (AGNISAR KRIYA) FOR REHABILITATION OF TYPE 2 DIABETES MELLITUS (T2D)

2021 ◽  
Vol 6 (11) ◽  
Author(s):  
Amit Chandra Deshmukh ◽  
Li Youqiang
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Statistical Analysis ◽  
The Other ◽  
Post Test ◽  
Level Of Significance ◽  
Paired T Test ◽  
Control Diabetes

The motive of this study was to find out the effect of Chain Yogic Exercise (Yogasana), Yogic Therapy (Agnisar Kriya) on Diabetes Mellitus (T2D). For the purpose of this study 200 subjects were selected and divided into two groups from Delhi, India. Both groups are experimental groups. In each group, 100:100 Type 2 Diabetes Mellitus (T2DM) subjects were distributed. There were 50 females and 50 males in each group i.e. half of the each group was female. The subjects’ age ranged between 35-45 years. One group was engaged in Chain Yogic Exercise (Yogasana) and the other group was perform Yogic Therapy (Agnisar Kriya), This process was for 90 days (30-30-30 days). The data was collected on the first day (dated 16th September 2020) of 1st round as pre-test and on the last day (dated 16th October 2020) of 1st round as post-test. For statistical analysis and interpretation of data, paired t-Test was employed. The level of significance had been taken 0.05 and 0.01. The study found Chain Yogic Exercise (Yogasana), Yogic Therapy (Agnisar Kriya) both has a significant effect to control Diabetes Mellitus (T2D). The study also found that Yogic Therapy (Agnisar Kriya) had much better effect to control Diabetes Mellitus (T2D) than Chain Yogic Exercise (Yogasana). <p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0796/a.php" alt="Hit counter" /></p>

scholarly journals Development of Type 2 Diabetes Mellitus Phenotyping Framework Using Expert Knowledge and Machine Learning Approach

2016 ◽  
Vol 11 (4) ◽  
pp. 791-799 ◽  
Author(s):  
Rina Kagawa ◽  
Yoshimasa Kawazoe ◽  
Yusuke Ida ◽  
Emiko Shinohara ◽  
Katsuya Tanaka ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Machine Learning ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Expert Knowledge ◽  
The Other ◽  
Learning Approach ◽  
Research Subjects ◽  
Machine Learning Approach

Background: Phenotyping is an automated technique that can be used to distinguish patients based on electronic health records. To improve the quality of medical care and advance type 2 diabetes mellitus (T2DM) research, the demand for T2DM phenotyping has been increasing. Some existing phenotyping algorithms are not sufficiently accurate for screening or identifying clinical research subjects. Objective: We propose a practical phenotyping framework using both expert knowledge and a machine learning approach to develop 2 phenotyping algorithms: one is for screening; the other is for identifying research subjects. Methods: We employ expert knowledge as rules to exclude obvious control patients and machine learning to increase accuracy for complicated patients. We developed phenotyping algorithms on the basis of our framework and performed binary classification to determine whether a patient has T2DM. To facilitate development of practical phenotyping algorithms, this study introduces new evaluation metrics: area under the precision-sensitivity curve (AUPS) with a high sensitivity and AUPS with a high positive predictive value. Results: The proposed phenotyping algorithms based on our framework show higher performance than baseline algorithms. Our proposed framework can be used to develop 2 types of phenotyping algorithms depending on the tuning approach: one for screening, the other for identifying research subjects. Conclusions: We develop a novel phenotyping framework that can be easily implemented on the basis of proper evaluation metrics, which are in accordance with users’ objectives. The phenotyping algorithms based on our framework are useful for extraction of T2DM patients in retrospective studies.

scholarly journals Pengaruh Senam PERSADIA 1 terhadap Lingkar Pinggang dan Rasio HDL-c LDL-c pada Wanita

2020 ◽  
Vol 2 (2) ◽  
pp. 94
Author(s):  
Hafizha Firdaus Al-Fuady ◽  
Bambang Purwanto ◽  
Soebagijo Adi Soelistijo
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Waist Circumference ◽  
Energy Intake ◽  
T Test ◽  
Paired T Test ◽  
Diabetes Melitus

AbstrakLatar Belakang: Diabetes melitus tipe 2 menjadi penyebab kematian nomer 3 di Indonesia. Kelebihan berat badan atau lingkar pinggang diatas normal dan kadar HDL-c rendah merupakan faktor risiko diabetes melitus tipe 2. Faktor risiko tersebut dapat diatasi salah satunya dengan olahraga. Senam PERSADIA 1 dirancang khusus untuk pencegahan diabetes. Namun, efek dari senam ini dalam menurunkan lingkar pinggang dan meningkatkan rasio HDL-c LDL-c belum pernah diteliti.Metode: Desain penelitian ini adalah eksperimen lapangan. Pengaruh Senam PERSADIA 1 terhadap lingkar pinggang dan rasio HDL-c LDL-c dianalisis dengan uji statistik deskriptif, uji normalitas saphiro wilk-test, uji beda berpasangan paired t-test / Wilcoxon-test.Hasil: Penelitian ini melibatkan 12 ibu-ibu PKK Lidah Wetan Gang V RW 2 Surabaya. Dari hasil analisis, terdapat penurunan rerata lingkar pinggang dan bermakna namun sedikit (p= 0,032), tidak ada peningkatan kadar HDL-c yang bermakna (p= 0,301), terdapat penurunan rerata LDL-c namun belum bermakna (p= 0,755), terdapat peningkatan rerata rasio HDL-c LDL-c namun belum bermakna (p= 0,303).Kesimpulan: Senam PERSADIA 1 dapat menurunkan lingkar pinggang namun sedikit dan belum dapat meningkatkan rasio HDL-c/LDL-c pada wanita secara bermakna menurut statistika. Diperlukan penelitian lebih lanjut dengan menambah waktu pelaksaan senam dan mengontrol energy intake subjek penelitian. Kata Kunci:. Diabetes melitus, Senam PERSADIA 1, lingkar pinggang, rasio HDL-c LDL-c, wanita AbstractBackground: Type 2 diabetes mellitus is the third causes of death in Indonesia. Overweight or waist circumference above normal and low HDL-c levels are risk factors for type 2 diabetes mellitus. One of the risk factors can be resolve with exercise. First series PERSADIA exercise is specifically designed for the prevention of diabetes. Howefer, the effect of this exercise in reducing waist circumference and increase ratio HDL-c LDL-c had never been proven.Method: The design of this study was a field experiment. The effect of first series PERSADIA exercise on waist circumference and HDL-c LDL-c ratio was analyzed by descriptive statistical test, saphiro wilk-test for normality test, paired t-test / Wilcoxon-test for different paired test.Result: This study involved 12 Women lived in Lidah Wetan Gang V RW 2 Surabaya. From the analysis, there was a decrease in mean waist circumference and significant but slightly (p = 0.032), there was no significant increase in HDL-c levels (p = 0.301), there was a decrease in LDL-c mean but it was not significant (p = 0.755), there was an increase in the mean HDL-c LDL-c ratio but it was not significant (p = 0.303).Conclusion: First series PERSADIA exercise has been able to reduce waist circumference but slightly and not able to increase HDL-c / LDL-c ratio significantly in women according to statistics. Further research is needed by increasing the exercise time and controlling the energy intake of subjects. Keywords: diabetes mellitus, first series PERSADIA exercise, waist circumference, HDL-c LDL-c ratio, women 

scholarly journals DEMONSTRASI PENGENALAN VARIASI MENU DIET DIABETES MELLITUS BAGI PENDERITA DIABETES MELLITUS TIPE 2

2021 ◽  
Vol 4 (1) ◽  
pp. 56
Author(s):  
Zuhria Ismawanti ◽  
Nastitie Cinintya Nurzihan ◽  
Nining Prastiwi
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Drug Management ◽  
Unhealthy Lifestyle ◽  
Type 2 Dm ◽  
Post Test ◽  
Diet Management ◽  
Level Of Understanding

Diabetes mellitus (DM) is a disease that can be caused by an unhealthy lifestyle. DM treatment has four pillars in its management, namely education, DM diet management, physical activity and drug management. The recommended DM dietary arrangement is almost the same as the recommended diet in general, namely balanced nutrition in accordance with calorie needs, however DM sufferers will emphasize eating regularity in terms of eating schedules, types of food and amount of food. Based on these problems, it is necessary to demonstrate the introduction of variations in the diabetes mellitus diet menu for type 2 diabetes mellitus sufferers.This activity is carried out to increase knowledge about the variety of diabetes mellitus diet menus in type 2 diabetes mellitus sufferers.Pre-test and post-test are carried out to determine the level of understanding of the demonstration which are given. The method used was to provide a demonstration of introduction to the variation of the diabetes mellitus diet menu for people with type 2 diabetes. As many as 25 people participated in this activity from beginning to end. Based on the results of the evaluation using the post test value, it shows that there is an increase in knowledge and skills regarding the variation of the type 2 DM diet, so as to prevent complications of type 2 DM.

scholarly journals Effect of Total Amount of Metformin HCl on the Characteristics of Metformin-Ca Alginate Microspheres

2019 ◽  
Vol 5 (1) ◽  
pp. 13 ◽  
Author(s):  
Dewi Melani Hariyadi ◽  
Noorma Rosita ◽  
Tiara Jeni Rosadi
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Statistical Analysis ◽  
Antidiabetic Drugs ◽  
Metformin Hydrochloride ◽  
Antidiabetic Drug ◽  
Ca Alginate ◽  
Metformin Hcl

Introduction: Metformin hydrochloride (metformin HCl) is an antidiabetic drug that is specifically used for type 2 diabetes mellitus (DM) and belongs to the biguanide antidiabetic drugs. Objective: The aim of this research was to determine the effect of total amount of metformin HCl on the characteristics of metformin HCl-Ca alginate microspheres using aerosolization technique. Methods: The total amount of metformin were 0.5 g (F1); 1 g (F2); 1.5 g (F3) and 2 g (F4). Drug was encapsulated into alginate and was crosslinked using CaCl2. Results: The results showed that drug loadings were 5.09%; 9.61%; 13.11%; and 15.09% respectively, while the entrapment efficiencies were 48.35%; 41.99%; 38.67%; and 30.53%. The yields were 80.92%; 74.12%; 68.27%; and 59.11% respectively. Based on the statistical analysis, it was found that there were significant differences between formulas. Particles of formulas decreased as the amount of drug increased. The resulting sizes were 1.82 μm (F1); 1.96 μm (F2); 2.1 μm (F3); and  2.97 μm (F4). Conclusion: It can be concluded that amount of drug significantly affected the characteristics of metformin-alginate microspheres.

scholarly journals A Study of Effect of Glycaemic Status on Pulmonary Function Test in Type 2 Diabetes Mellitus

2021 ◽  
Vol 10 (18) ◽  
pp. 1343-1346
Author(s):  
Basavaraj G.T ◽  
Mudassir Indikar ◽  
Malingaraya Negali
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Pulmonary Function ◽  
Pulmonary Function Test ◽  
Pulmonary Complications ◽  
The Other ◽  
Duration Of Diabetes ◽  
Function Test

BACKGROUND Diabetes mellitus is a metabolic disorder precipitating micro vascular, macro vascular complications and peripheral vascular diseases. Pulmonary complications of diabetes mellitus have been poorly characterised. Glycaemic status has shown varied impact on lung functions. In type-2 diabetes there is resistance to insulin action and also inadequate insulin secretion. Diabetes mellitus is associated with morphological and functional abnormalities. Several studies have shown that diabetes is associated with impaired pulmonary function. Pulmonary complications of diabetes mellitus (DM) have been poorly characterised. Some authors have reported normal pulmonary functions and even concluded that spirometry is not at all necessary in diabetic patients. We wanted to highlight the evidence-based significance of spirometry. METHODS This cross-sectional study was done for a period of 1 year from September 2017 to July 2018. The study sample consisted of 50 type-2 diabetes patients and 50 controls. RESULTS A total of 100 subjects were included in the present study; 50 of them were diabetics and the other 50 were non-diabetic controls matched by age, sex and body mass index (BMI). The range of forced vital capacity (FVC) in diabetic group was from 1.36 litres, which is lesser than range in controls (2.06 litres). Forced expiratory volume (FEV1) / FVC ranged from 0.59 in diabetics compared to 0.84 in controls. Mean FVC value was higher in diabetics with a duration of diabetes of less than 5 years (2.72) as compared to those with diabetes of more than 5 years (2.03) with a P value of 0.0004 which is statistically significant. CONCLUSIONS Type 2 diabetes mellitus is associated with restrictive pattern of respiratory abnormality. As the duration of diabetes increases the restrictive profile was more prominent. There was inverse relation between glycaemic status and spirometric indices FEV1 and FVC. Thus, an intensive glycaemic management may reduce the risk of death through an improved ventilator function which is independent of the other beneficial effects. KEY WORDS Pulmonary Function Test, Type 2 Diabetes Mellitus, Glycaemic Status

scholarly journals Pengaruh Jalan Sehat terhadap Kualitas Hidup Penderita Diabetes Mellitus Tipe 2 di Puskesmas

2018 ◽  
Vol 11 (1) ◽  
pp. 1
Author(s):  
Ihsan Taufiq
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Psychological Health ◽  
Control Group ◽  
Test Design ◽  
Post Test

<p><strong><em>Background:</em></strong><em> </em><em>Diabetes Mellitus (DM) causes a decrease in quality of life in all domains. The most often overlooked cause of DM patients is not carrying out physical activity regularly. </em><strong><em>Purpose:</em></strong><em> </em><em>The purpose of this study was to determine the effect of healthy pathways on the quality of life of type 2 D</em><em>M</em><em> patients in the Health Center in Kotabumi North Lampung in 2017.</em><em> </em><strong><em>Methods:</em></strong><em> </em><em>This study used quasi-experimental pre-post test design with a control group. The number of samples consisted of treatment groups and control groups, each group of 22 respondents. The treatment group was the respondents who carried out healthy walks of intervention, then measured the quality of life of patients with type 2 diabetes mellitus, while the control group did not carry out healthy walking activities. Data analysis uses t test dependent. </em><strong><em>Results:</em></strong><em> </em><em>The results showed that there was an effect of healthy pathways on the quality of life of patients with type 2 diabetes mellitus in the health centers in Kotabumi, North Lampung (p = 0.007). <strong>Conclusions</strong></em><strong><em>:</em></strong><em> Healthy paths improve the quality of life for patients with type 2 diabetes, including aspects of physical health, psychological health, social and environmental relations. </em></p><p><strong>Latar Belakang:</strong> Penyakit Diabetes Mellitus (DM) menyebabkan penurunan kualitas hidup disemua domain. Penyebab yang paling sering diabaikan penderita DM adalah tidak melaksanakan aktivitas fisik secara teratur. <strong>Tujuan: </strong>Tujuan penelitian ini untuk mengetahui pengaruh jalan sehat terhadap kualitas hidup penderita DM tipe 2 di Puskesmas wilayah Kotabumi Lampung Utara Tahun 2017. <strong>Metode:</strong> Penelitian ini menggunakan <em>kuasi eksperimen pre post test design </em> dengan kelompok kontrol. Jumlah sampel terdiri atas kelompok perlakuan dan kelompok kontrol masing-masing kelompok 22 responden. Kelompok perlakuan adalah responden yang dilakukan intervensi jalan sehat, kemudian dilakukan pengukuran kualitas hidup penderita DM tipe 2, sedangkan kelompok kontrol tidak melakukan kegiatan jalan sehat. Analisis data menggunakan <em>t </em><em>test dependent</em>. <strong>Hasil:</strong> Hasil penelitian menunjukkan terdapat pengaruh jalan sehat terhadap kualitas hidup penderita DM tipe 2 di Puskesmas wilayah Kotabumi Lampung Utara (p=0,007). <strong>Simpulan:</strong> Jalan sehat meningkatkan kualitas hidup penderita DM tipe 2 meliputi aspek kesehatan fisik, kesehatan psikologis, hubungan sosial dan lingkungan.</p>

scholarly journals Correlation of Surrogate Markers of Insulin Resistance with Fasting Insulin in Type 2 Diabetes Mellitus Patients: A Study of Malwa Population in Punjab, India

2021 ◽  
Author(s):  
Navneet Kaur ◽  
Gitanjali Gitanjali ◽  
Ravinder Garg ◽  
Chaitanya Tapasvi ◽  
Sonia Chawla ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Statistical Analysis ◽  
Surrogate Markers ◽  
Fasting Insulin ◽  
Kappa Test ◽  
Type 2 Dm

Abstract Context Insulin resistance (IR) and abnormal insulin secretion play a key role for the development of type 2 diabetes mellitus (DM). Aims We investigated the surrogate markers of IR, i.e., Homeostasis Model Assessment (HOMA), Quantitative Insulin Sensitivity Check Index (QUICKI), McAuley, and Fasting Insulin Resistance Index (FIRI) in type 2 DM patients. Also, fasting insulin (FI) levels were estimated in type 2 diabetics. Further, the correlation of FI with other surrogate markers of IR in type 2 DM was done. Settings and Design A hundred newly diagnosed patients with type 2 DM from Malwa population, Punjab, were considered for evaluation. Another 100 healthy individuals (age and sex-matched) were examined as controls. Methods and Material Fasting blood glucose, FI, and lipid profile were estimated, and IR was calculated using McAuley index (McA), HOMA, QUICKI, and FIRI. Statistical Analysis Used The statistical analysis was performed on the above-mentioned clinical interpretations. The Cohen’s kappa test was used to affirm the agreement. Results FI levels in patients with type 2 diabetes were significantly higher (20.8 ± 9.05 µIU/L) than controls (7.93 ± 1.01 µIU/L). IR by surrogate markers was found significant in the study group. The 76% patients with type 2 diabetes ended up as resistant to insulin by FI measurement, almost equivalent to McA, 80%; HOMA, 88%; FIRI, 88%; and QUICKI, 90%. A notable correlation was highlighted between FI and McA manifesting IR (p < 0.01, r = −0.85). We calculated the statistical correlation of FI with HOMA, QUICKI, and FIRI indices (p < 0.01, r = 0.93; p < 0.01 r = −0.92; and p < 0.01, r = +0.93, respectively). The agreement visible from Cohen’s kappa test also affirms the same (k = 0.9 for McA). Conclusion We concluded that all the surrogate markers for IR were specific when compared with FI, but in terms of sensitivity McA was found to be more sensitive as it includes markers of dyslipidemia, which is the precipitating factor of metabolic derangements so as the IR in type 2 DM.

scholarly journals Effects of Duration and Complications of Type 2 Diabetes Mellitus on Diabetic Related Parameters, Adipocytokines and Calcium Regulating Hormones

2019 ◽  
pp. 2335-2361
Author(s):  
Aseel Khalid Thabah Al-Attaby ◽  
Makarim Qassim Dawood Al-Lami
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
The Other ◽  
Diabetic Patients ◽  
The Third ◽  
First Category ◽  
Duration Of Disease

The present study aims to investigate the effects of duration and complications of type 2 diabetes mellitus on diabetic related parameters, adipocytokines and calcium regulating hormones. This study was conducted on eighty diabetic patients (41 male and 39 female) in Iraq, with an age range of 20-60 years and a disease duration range of 1-180 months. Blood samples were collected from the patients to determine three main types of biomarkers: diabetic-related parameters [Fasting blood sugar is FBS glycated hemoglobin (HbA1c), insulin, and insulin resistance (IR)], adipocytokines [adiponectin and tumor necrosis factor-α (TNF-α), and calcium regulating hormones [parathyroid hormone (PTH), calcitonin, and vitamin D].      The result showed increased levels of some parameters with the increase in duration of disease. Levels of FBS and HbA1c increased significantly (probability <0.05) in the second and the third categories of duration of disease (61-120 and 121-180 month) compared with the first category (1-60 month). Levels of insulin and IR were increased with the increase in duration of disease; this increase was found to be significant (p<0.05) when a comparison was made between the second and the third categories with the first category. Also, a similar trend was observed when a comparison was made between the third category and the second category. There was a significant (P<0.05) increase in the levels of TNF-α and calcitonin in the last category compared with the other categories, and a significant (P<0.05) increase in vitamin D levels in the last category compared with the first category. Non-significant (P>0.05) differences were found in the levels of adiponectin and PTH among all categories of duration of disease.      When a comparison was made between the two groups of patients (with complications and without complications), a significant (P<0.05) increase was found in the levels of FBG, HbA1c, insulin, and IR in patients with complications as compared with patients without complications. A significant (P<0.05) decrease was found in calcitonin levels in patients with complications as compared with patients without complications. Non-significant (P>0.05) differences were found in the levels of the other parameters (adiponectin, TNF-α, PTH and vitamin D) between the two groups of patients.      It can be concluded from the present study that duration of disease affects diabetic related parameters, TNF-α and some calcium regulating hormones (calcitonin and vitamin D), while complications of disease affect diabetic related parameters and calcitonin. It can be suggested that the duration of diabetes is one of the strongest determinants of complication risk.

Aerobic Exercise Decrease Cholesterol Levels in Type 2 Diabetes Mellitus Patients

2018 ◽  
Vol 13 (1) ◽  
pp. 8
Author(s):  
Cecep Triwibowo ◽  
Evi Nurjannah ◽  
Ikha Fitriyana ◽  
Yulia Fauziyah
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
T Test ◽  
Group Design ◽  
Cholesterol Levels ◽  
Before And After ◽  
Patients With Diabetes ◽  
Post Test

<p>Elevated  cholesterol  level is one of  the risks  for cardiovascular disease  in diabetes mellitus. Exercise is one of therapy in patients with diabetes mellitus. The purpose of this study is to determine the effect of exercise on decrease cholesterol levels in patients with diabetes mellitus. This study used pre-post test one group design. Twenty-two patients with diabetes mellitus followed the intervention which is a twice a week exercise for 4 weeks. Cholesterol levels were measured before and after exercise. Data were analyzed by  dependent T-test. Cholesterol  levels in patients with  diabetes  mellitus before  the exercise reached 261.18±49.013 mg/dL and after intervention decreased to 224.41±26 mg/dL. Dependent t-test showed differences in cholesterol levels before and after exercise in patients with diabetes mellitus (p&lt;0.05). Exercise can lower cholesterol levels in patients with diabetes mellitus.</p>

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