scholarly journals Pharmacognostical and Phytochemical Evaluation of Haridra (Curcuma Longa Linn.)

AYUSHDHARA ◽  
2021 ◽  
pp. 3309-3315
Author(s):  
Prachisha.P.C ◽  
Sumit Nathani
Keyword(s):  
Tamil Nadu ◽  
Andhra Pradesh ◽  
Curcuma Longa ◽  
Phytochemical Analysis ◽  
Present Sample ◽  
Anti Cancer ◽  
North Eastern ◽  
Anti Oxidant ◽  
Increasing Demand

Curcuma longa Linn. is a very commonly used herb in the day-to-day life for therapeutic and culinary purposes. Haridra commonly known as ‘Golden spice’ belongs to Zingiberaceae  family and is very well known for its pharmacological actions like hepatoprotective, anti-allergic, immune-stimulant, anti-cancer, anti-tumor, anti-hyperlipidemic, anti-oxidant, anti-microbial, anti-diabetic etc. According to the growing regions there are so many varieties of Haridra like Kerala, Tamil Nadu, Maharashtra, Andhra Pradesh, Orissa and North Eastern varieties. All medicinal plants contain phytochemicals or bioactive compounds which plays the key role in its therapeutic action. Most of the drugs show variations in these phytochemicals due to its growing regions which results in severe variations of its quality and efficacy. Also the globalisation and increasing demand for Ayurveda drugs resulted in unavailability of authentic and quality drugs in market which meets the quality standards. Objective: Kerala variety of Turmeric is very well known for its high Curcumin, which is up to 6.5%. Present study is to evaluate the quality of Kerala variety of Haridra sample. Material and methods: This study involves pharmacognostical and phytochemical analysis of Kerala variety of Haridra samples to ensure its purity, safety and quality. Observations and Results: All the findings of the phytochemical and pharmacognostical study were within the standards of quality as per API. Conclusion: The present sample of Haridra, the Kerala variety was found to be rich in Quality and was safe, pure and authentic.

scholarly journals Medicinal properties of Abutilon indicum

2018 ◽  
Vol 1 (1) ◽  
pp. 1-4
Author(s):  
S Rajeshwari ◽  
SP Sevarkodiyone
Keyword(s):  
Medicinal Plant ◽  
Traditional Medicine ◽  
Phytochemical Analysis ◽  
Vaginal Infections ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Medicinal Properties ◽  
Anti Inflammatory ◽  
Larvicidal Activities ◽  
Abutilon Indicum

Abutilon indicum is a common Indian shrub, belonging to the family Malvaceae; Also known as Mallow in english, Abutilon indicum is used as a medicinal plant. It has been extensively used as a traditional medicine as a laxative, emollient, analgesic, anti-diabetic, anti-inflammatory and blood tonic agent and also in the treatment of leprosy, urinary disease, jaundice, piles, relieving thirst, cleaning wounds and ulcers, vaginal infections, diarrhea, rheumatism, mumps, pulmonary tuberculosis, bronchitis, allergy, blood dysentery, some nervous and some ear problems. Various studies on the plant extract have been performed to confirm the anti-oxidant, anti-bacterial, analgesic, anti-inflammatory, anti-cancer, hepato-protective, immuno-modulatory and larvicidal activities of the plant. This plant is often used as a medicinal plant and is considered invasive on certain tropical islands. In traditional medicine, A. indicum is used as a aphrodisiac, demulcent, diuretic, laxative, pulmonary and sedative (leaves). The bark is astringent and diuretic; laxative, expectorant and demulcent (seeds); laxative and tonic, anti-inflammatory and anthelmintic (plant); analgesic (fixed oil); diuretic and for leprosy (roots). The plant is very much used in Siddha medicines. In fact, the bark, root, leaves, flowers and seeds are all used for medicinal purposes by Tamils. The leaves are also used to treat for pile complaints. The flowers are traditionally used to increase semen in men. The phytochemical analysis showed the Presence of Alkaloid, Saponins, Amino acid, Flavonoids, Glycosides and steroids. This plant exhibits several potential pharmacological activities. A review on the various studies on the plant has been provided for the purpose of understanding its medicinal properties.

scholarly journals Liriopogons (Genera Ophiopogon and Liriope, Asparagaceae): A Critical Review of the Phytochemical and Pharmacological Research

2021 ◽  
Vol 12 ◽  
Author(s):  
Feiyi Lei ◽  
Caroline S. Weckerle ◽  
Michael Heinrich
Keyword(s):  
Myeloid Leukemia ◽  
Scientific Evidence ◽  
Bioactive Metabolites ◽  
Therapeutic Uses ◽  
Anti Cancer ◽  
Ophiopogon Japonicus ◽  
Anti Oxidant ◽  
Methodological Problems ◽  
Available Information

The closely related genera Liriope and Ophiopogon (Asparagaceae), collectively known in English as liriopogons, have similar therapeutic uses in treating cough, rheumatoid arthritis, and cleaning heat. The main aim of this review is to understand the current phytochemical and pharmacological knowledge including an assessment of the quality of the scientific evidence. A literature search was conducted in line with PRISMA guidelines, by retrieving available information up to 2020 from five online resources. The bioactive metabolites of liriopogons include steroidal saponins, flavonoids, polysaccharides, organic acids, phenols. Cardiovascular protective, anti-inflammatory, anti-diabetic, anti-oxidant, anti-cancer, neuroprotective, anti-viral, anti-acute myeloid leukemia and hepatoprotective effects have been at the center of attention. From a toxicological perspective Ophiopogon japonicus seems to be safe. Some problems with the quality of the pharmacological evidence stand out including the application of excessive dose level and methodological problems in the design. Additionally, a reasonable link between local/traditional uses and pharmacological assessment is often vague or not reflected in the text. Future researches on liriopogons are required to use rigorous scientific approaches in research on evidence-based natural products for the future benefits of patients.

Anti-Angiogenic Activity of Curcumin in Cancer Therapy: A Narrative Review

2019 ◽  
Vol 17 (3) ◽  
pp. 262-269 ◽  
Author(s):  
Abolfazl Shakeri ◽  
Natalie Ward ◽  
Yunes Panahi ◽  
Amirhossein Sahebkar
Keyword(s):  
Curcuma Longa ◽  
Tumour Microenvironment ◽  
Pharmacological Activities ◽  
Angiogenic Activity ◽  
Tumour Metastasis ◽  
Naturally Occurring ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Apoptotic Pathways ◽  
Cell Signaling Pathways

Curcumin is a naturally occurring polyphenol isolated from Curcuma longa that has various pharmacological activities, including, anti-inflammatory, anti-oxidant and anti-cancer properties. The anticancer effect of curcumin is attributed to activation of apoptotic pathways in cancer cells, as well as inhibition of inflammation and angiogenesis in the tumour microenvironment and suppression of tumour metastasis. Angiogenesis, which is the formation of new blood vessels from pre-existing ones, is a fundamental step in tumour growth and expansion. Several reports have demonstrated that curcumin inhibits angiogenesis in a wide variety of tumour cells through the modulation of various cell signaling pathways which involve transcription factors, protein kinases, growth factors and enzymes. This review provides an updated summary of the various pathways and molecular targets that are regulated by curcumin to elicit its anti-angiogenic activity.

INTERNATIONAL CONVENTIONS ON SUSTAINABLE DEVELOPMENT AND INDIA'S STRATEGIES

2021 ◽  
pp. 46-48
Author(s):  
R. Bharathi ◽  
V. Mohanasundaram
Keyword(s):  
Quality Of Life ◽  
Sustainable Development ◽  
Tamil Nadu ◽  
Andhra Pradesh ◽  
Environmental Parameters ◽  
Policy Initiatives ◽  
The Government ◽  
International Conventions ◽  
Human Kind

The goal of sustainable development has to be achieved so as to maintain not only rate of economic growth but also the quality of life in terms the relevant environmental parameters. The realization of the dangers of pollution of all types, across the countries, made the human kind to think of alternatives. Towards this the international orgranisations like UNO have convened a number of Meets, Summits, Conferences, Conventions, Protocol and Accords. A brief analysis of the relevant international conventions was done to bring home the point that achievement of sustainable goals was not an easier task. Then a description of each of the 17 SDGs and the policy initiatives taken by the Government of India were taken up. It was found that among the 28 states of Indian Union, ve states namely Kerala, Himachal Pradesh, Andhra Pradesh, Tamil Nadu and Telangana took the rst three ranks in the SDG Index (2019).

scholarly journals POTENTIAL AND THERAPEUTIC BENEFITS OF TINOSPORA CORDIFOLIA

2021 ◽  
Vol 10 (3) ◽  
pp. 2965-2970
Author(s):  
Prashant L Pingale ◽  
Keyword(s):  
Tinospora Cordifolia ◽  
Immunomodulatory Activity ◽  
Antipyretic Activity ◽  
Therapeutic Benefits ◽  
Anti Cancer ◽  
Potential Benefits ◽  
Anti Oxidant ◽  
Large Application ◽  
Ayurvedic Treatment

Essential crude products with potential benefits are steadily achieving significance in clinical studies and research because of their quality of minimal adverse effects as associated with allopathic medications. Tinospora cordifolia usually recognized as Guduchi is known for its large application in the therapy and cure of various diseases in conventional ayurvedic treatment. Recently the classification of active constituents of Guduchi and their inherent function in disease limitation has led us to an active activity in the plant around the globe. This review comprises the genetic variety of the parts of Tinospora cordifolia and active ingredients isolated from Tinospora cordifolia and helps in treating diseases due to their potential benefits such as Anti-oxidant activity, Anti-diabetic activity, Immunomodulatory activity, Anti-cancer activity, Anti-toxic effect, Anti-hyperlipidemic Property, Analgesic, anti-inflammatory, antipyretic activity, and many others. This review aims to utilize the biochemical and significant routes induced by the aggregates separated from Tinospora cordifolia to allow different and efficient therapeutic formulations in disease elimination.

Educational Problems of Children Orphaned by AIDS: A Study in Krishna, YSR Kadapa and Karimnagar Districts of Andhra Pradesh

2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Mutluri Abraham ◽  
A.B.S.V. Ranga Rao
Keyword(s):  
Tamil Nadu ◽  
Andhra Pradesh ◽  
Basic Education ◽  
Group Discussions ◽  
Aged People ◽  
Aids Orphans ◽  
Living With Hiv ◽  
The Impact ◽  
Hiv Aids

HIV/AIDS is one of the major social problems in developing countries like India. In 1986, the first HIV case was diagnosed by Dr. Suniti Salmon in a female sex worker from Tamil Nadu, India. Then gradually the HIV has been transmitted and diagnosed in all states of India. More than 6 million people in India are living with HIV/AIDS. The impact of HIV/AIDS is more on children, women and aged people. According to NACO, more than 2.1 million children, below age of 18 years have been orphaned as a result of AIDS. NACO defined AIDS orphan is a child who is less than 18 years of age whose mother or father or both have died of HIV/AIDS. This study makes an attempt to analyze the situation of AIDS orphans in three high prevalent districts of united Andhra Pradesh i.e. Krishna, YSR Kadapa, and Karimnagar, India. The study analyzed socio-economic demographic profile of the AIDS orphans, perceived stigma and discrimination, educational and psychological problems faced by AIDS orphans and suggested the better interventions to promote the quality of life among AIDS orphans. The study collected data from 316 AIDS orphans and also conducted 6 focus group discussions. The study found that there are many challenges facing by AIDS orphans to access the basic education.

scholarly journals The Multifaceted Therapeutic Mechanisms of Curcumin in Osteosarcoma: State-of-the-Art

2021 ◽  
Vol 2021 ◽  
pp. 1-15
Author(s):  
Fatemeh Zahedipour ◽  
Monireh Bolourinezhad ◽  
Yong Teng ◽  
Amirhossein Sahebkar
Keyword(s):  
Survival Time ◽  
Signaling Pathways ◽  
Intracellular Signaling ◽  
Molecular Mechanisms ◽  
Curcuma Longa ◽  
Potential Candidate ◽  
Anti Cancer ◽  
Adults And Children ◽  
Anti Oxidant ◽  
Therapeutic Mechanisms

Osteosarcoma is a major form of malignant bone tumor that typically occurs in young adults and children. The combination of aggressive surgical strategies and chemotherapy has led to improvements in survival time, although individuals with recurrent or metastatic conditions still have an extremely poor prognosis. This disappointing situation strongly indicates that testing novel, targeted therapeutic agents is imperative to prevent the progression of osteosarcoma and enhance patient survival time. Curcumin, a naturally occurring phenolic compound found in Curcuma longa, has been shown to have a wide variety of anti-tumor, anti-oxidant, and anti-inflammatory activities in many types of cancers including osteosarcoma. Curcumin is a highly pleiotropic molecule that can modulate intracellular signaling pathways to regulate cell proliferation, inflammation, and apoptosis. These signaling pathways include RANK/RANKL, Notch, Wnt/β-catenin, apoptosis, autophagy, JAK/STAT, and HIF-1 pathways. Additionally, curcumin can regulate the expression of various types of microRNAs that are involved in osteosarcoma. Therefore, curcumin may be a potential candidate for the prevention and treatment of osteosarcoma. This comprehensive review not only covers the use of curcumin in the treatment of osteosarcoma and its anti-cancer molecular mechanisms but also reveals the novel delivery strategies and combination therapies with the aim to improve the therapeutic effect of curcumin.

PRELIMINARY PHYTOCHEMICAL ANALYSIS OF SELECTED MEDICINAL PLANTS OF NORTH EASTERN REGION OF INDIA

2018 ◽  
Vol 7 (4) ◽  
pp. 88-97
Author(s):  
MELAKYRKHU NIANGMIH ◽  
SAMIRAN CHUTIA ◽  
DAS BANYASHREE ◽  
SARKAR BAPI ROY ◽  
DEY BIPLAB KUMAR ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Phytochemical Analysis ◽  
Eastern Region ◽  
North Eastern

India Higher Education Atlas: Andhra Pradesh, Goa, Karnataka, Kerala, Puducherry, Tamil Nadu, Telangana - Volume 5

2018 ◽  
Author(s):  
Teja Malladi ◽  
Dhananjayan Mayavel ◽  
Nilakshi Chatterji ◽  
Pratyush Tripathy
Keyword(s):  
Higher Education ◽  
Tamil Nadu ◽  
Andhra Pradesh

Comparative Pharmacognostic, Physicochemical and Phytochemical Studies of Different Samples of Plumbago zeylanica L. Roots

2017 ◽  
Vol 9 (06) ◽  
Author(s):  
Neha Jain ◽  
Mohan Lal Kori
Keyword(s):  
Phytochemical Analysis ◽  
Local Market ◽  
Herbal Drugs ◽  
Disease Treatment ◽  
Organoleptic Evaluation ◽  
Plumbago Zeylanica ◽  
Qualitative And Quantitative ◽  
Crude Drugs ◽  
Phytochemical Studies

The objective of the present study is to evaluate the quality of the marketed and self collected samples of Plumbago zeylanica L. roots on the standardization parameters. This study is planned mainly to confirm changes with quality of drug. Now a day’s more demand of herbal drugs for disease treatment, lack of knowledge of proper methodology and availability are promoting the practices of adulteration and substitution. Thus, the standardization of the plant crude drugs is necessary to maintain their therapeutic efficacy. Comparative studies were carried out to evaluate the standards of P. zeylanica L. with emphasis on organoleptic evaluation, physicochemical and phytochemical analysis. Samples were procured from local market and self collected to determine the qualitative and quantitative variations. The result indicates that self collected sample showed significant results with comparison to marketed sample.

Sign in / Sign up

Export Citation Format

Share Document