scholarly journals Pharmaceutico-Analytical Study of Vatavidhvamsana Rasa

2020 ◽  
Vol 11 (2) ◽  
pp. 235-240
Author(s):  
Mahesh S ◽  
Neethu S Pillai ◽  
Praveen Kumar K S ◽  
Dilip Prajapati ◽  
Patgiri B J

Vatavidhvamsana rasa (VVR) is a well-known herbo-mineral formulation explained in classical ayurvedic text Yogaratnakara and also quoted in Ayurveda Formulary of India (AFI) and is mainly indicated for Vatika disorders. There is a lack of data regarding the standardization of pharmaceutical process and analytical profile of VVR. Aim: To prepare vatavidhvamsana rasa and analyze it using various physicochemical parameters. Materials and methods: Total three batches of Vatavidhvamsana Rasa was prepared as per the classical method explained in the reference to evaluate the standard procedure. During the pharmaceutical process, all ingredients were mixed thoroughly and triturated thirty times with ten bhavana drugs for an average of 90 hours. The pharmaceutical and analytical parameters were completed and the data was recorded. Results: Three batches of Vatavidhvamsana Rasa after preparation showed an average increase of 12.93% yield. Pharmacognostical evaluation showed the presence of the ingredients used. Average values of physicochemical parameters of Vatavidhvamsana Rasa were as follows: loss on drying 6.19, pH 7, total ash value 36.46, acid insoluble ash 7.16, water soluble extractive value 17.24, alcohol soluble extractive value 7.13.  HPTLC of Vatavidhvamsana Rasa revealed a total of 11 and 12 bands at 254 nm and 366 nm. Conclusion: Data generated from pharmaceutical, analytical studies and HPTLC can be used to develop a preliminary standard profile for the formulation Vatavidhvamsana Rasa.

Author(s):  
Nandurkar Vishal Marotrao ◽  
V. M. Ramteke ◽  
S.G. Jyotishi

Trinetraras is a Kharliya Rasayan mentioned in Yogratnakar for the treatment of Hridroga (Yogratnakar Uttarardha Hridroga Chikitsa 1,2). It consists of Shuddha Parad, Shuddhagandhak and Abhrakbhasma where Bhavanadravya is Arjuna bark decoction. Aim: Pharmaceutical and analytical study of Trinetraras. Materials and methods: Paradshodhan, Gandhakshodhan, Vajrabhrakshodhan, Dhanyabhraknirmana, preparation of Abhrakbhasma, preparation of Kajjali are the procedures required to be performed before the preparation of Trinetraras. Total 40 times Abhrak was subjected to Maransanskar in Gajaputa (40 puti Abhrakbhasma). Trinetraras can be prepared from Shuddha Parad, Shuddhagandhak and Abhrakbhasma, Arjuna bark decoction is needed for 21 Bhavana. Total three batches of Trinetra Ras were prepared as per the classical method mentioned in the reference. Observations and results: Prepared samples of Trinetraras and Abhrakbhasma were tested on the basis of organoleptic and physicochemical parameters. Along with Ayurvedic parameters modern parameters such as L.O.D., L.O.I., pH, conductivity, successive solubility, elemental assay of Hg, S and Fe, TLC, phenolic assay etc. were applied to the samples of Trinetraras. Conclusion: Analytical study of Trinetraras revealed the uniformity of the procedures in the three samples of Trinetraras, as evidenced by the observations of the analytical values of the three samples were not much variation found. Analytical profile showed the presence of the ingredients used. Data generated from pharmaceutical, analytical studies can be used to develop a preliminary standard profile for the formulation of Trinetra Ras.


2020 ◽  
Vol 8 (9) ◽  
pp. 4381-4384
Author(s):  
Renu Prasad ◽  
Gunjan Sharma ◽  
Radhika Menon ◽  
Aditi 4

Shatahwadi ghrita is an Ayurvedic formulation mentioned in Ashtanga hridaya in the management of Timira. The main contents of this Ghrita are Shatahwa, Nalada, Kakoli, Ksheerakakoli, Yashtimadhu, Pra-poundarika, Sarala, Pippali, Devadaru. It’s prepared by classical method of Ghrita kalpana. Aim: To prepare and do the physio-chemical study of finished product. Materials and Methods: Shatahwadi ghrita is a polyherbal formulation which is formulated by classical method of Ghrita paka. It contains drugs having properties such as Tridoshahara, Chakshushya and Ra-sayana. Results: Standardization of Shatahwadi ghrita shows remarkable results regarding Refractive index, sapon-ification value, iodine value, peroxide value etc. Conclusion: The prepared Shatahwadi ghrita matches the physicochemical parameters and can impact good therapeutic impact.


Author(s):  
DIBYENDU SHIL ◽  
DAMIKI LALOO ◽  
SMRITI REKHA CHANDA DAS ◽  
SUVAKANTA DASH

Objective: To evaluate the pharmacognostical and phytochemical parameters of Physalis minima leaf. Methods: The leaf of Physalis minima was examined for macroscopical, microscopical, physicochemical parameters and fluorescence analysis. Extracts obtained from the leaf was analyzed for phytochemical screening and estimation of total tannin, phenolic and flavonoid content following the standard procedure available in the literature. Results: Morphologically, the leaf was found to be ovate in shape, 5 to 8 cm long and up to 3 cm width with dentate margin, asymmetrical base, hairy surface, reticulate veins on each side of midrib, green in colour, characteristic odour and slight bitter in taste. Microscopic study has shown the important diagnostic characters of Solanaceae family which is characterized by presence of dorsiventral leaf with anomocytic stomata, grandular or uniseriate trichomes and cluster crystal of calcium oxalate. Physicochemical parameters like foreign organic matter (0.78%), loss on drying (8.23%), total ash (11.4%), acid insoluble ash (2.2%), water-soluble ash (6.1%), sulphated ash (2.4%) alcohol soluble extractive (10.4%), water-soluble extractive (9.5%), ether soluble extractive (1.8%) foaming index (below 100), swelling index (1), volatile oil and heavy metal content were quantified. Phytochemical analysis of different extracts of Physalis minima leaf has shown the presence of phytoconstituents viz. alkaloids, steroids, tannin, flavonoids, protein. Quantification of phytoconstituents was also reported like phenols (10.59±0.65 mg/gm equivalent to tannic acid), tannin (8.24±0.27 mg/gm equivalent to tannic acid) and flavonoids (87.17±0.87 mg/gm equivalent to rutin) respectively. Conclusion: This present study was provided the qualitative and quantitative standard of Physalis minima will help to prevent the possible steps of adulteration with other species of the same genus.


Author(s):  
Bibin K. B.

Background: Sneha Kalpana is one among the several highly established Kalpana of Ayurvedic system of medicine. Many types of Taila Kalpana are mentioned in Ayurvedic classics and used effectively in therapeutic practice. Tila Taila is the most commonly using Taila. However Narikelataila, Erandataila, Sarshapataila, etc, are also used in special conditions. It is interesting to note that certain preparations are available in the market based on both TilaTaila and Narikela Taila. This is an attempt to comparatively evaluate the formulation Dhutturadi Taila prepared in Tila Taila and Narikela Taila as the bases. Dhutturadi Taila mentioned in Sahasrayogam is taken for the present study. Objectives: To comparatively analyse Dhutturadi Taila samples with classical and advanced analytical techniques. Materials and Methods: Dhutturadi Taila was prepared using two media i.e. Narikela Taila and Tila Taila. Both Taila samples were comparatively analysed with suitable physicochemical parameters and advanced instrumental methods of analysis. Conclusion: As per the existing result it seems that more amount of marker components are extracted into Tila Taila medium when compared with Narikela Taila.


Author(s):  
Jigyasa Pathak ◽  
Aswathi M. P. ◽  
B. R. Patel ◽  
Harisha C. R. ◽  
Shukla Vinay J.

Background: Desmodium velutinum (Fabaceae) is one of the wild edible plants used traditionally to treat diarrhoea, haematuria, infertility and also externally used to treat scorpion bites. Though various parts of the plant have been used for therapeutic purpose, panchanga of the plant has not been studied for its Pharmacognostical and phytochemical characteristics in detail, following scientific parameters. Hence in the present study Desmodium velutinum whole plant has been studied for its pharmacognostical and phytochemical characters and compared with commonly used species Desmodium gangeticum. Methods: Whole plant of Desmodim velutinum was collected from Paikmal, Odisha and Desmodium gangeticum was collected from Junagarh, Gujarat in the month of November 2019 following good collection practices and shade dried. Pharmacognostical study and analytical study were performed following standard pharmacopoeial procedures. Results: Whole plant (Panchanga) of former is sweetish and latter is bitter. Powder microscopy of Desmodium gangeticum showed presence of rhomboidal crystals and lignified annular and spiral vessels. Desmodium velutinum showed presence of prismatic crystals and lignified pitted vessels. Physico-chemical analysis showed higher loss on drying in Desmodium gangeticum, and higher water soluble extractive values of Desmodium velutinum. Phytochemical estimation showed the presence of Proteins, tannins, and carbohydrates in both samples. HPTLC study showed similar Rf value 0.82 and 0.94 at 254 and 0.03 and 0.41 at 366nm. Conclusion: Basing upon the analytical and microscopic similarities Desmodium velutinum may be considered as substitute of Desmodium gangeticum


2020 ◽  
Vol 5 (05) ◽  
pp. 206-213
Author(s):  
Jyothi S. Murthy ◽  
B. R. Lalitha ◽  
Aahalya Sharma

Lagerstroemia speciosa (L.) Pers (Hindi - Jarul, Taglog - Banaba) a member of Lythraceae family is found all over India, specially in Bengal, Assam and Deccan Peninsula. The leaves of L. speciosa is widely used for lowering blood sugar levels in Philippines, Japan and Taiwan. Pharmacognostical investigation of leaves of L. speciosa was done by evaluating its morphological, microscopical studies, Physicochemical and phytochemical parameters. Rasa Nirdharana was done. Microscopical study revealed presence of epidermal cells contained clusters of rosette aggregate calcium oxalate crystals and few cells were mucilaginous. Lower epidermis showed the presence of anomocytic stomata. Physical constants of leaf powder showed, loss on drying - 3.8%, total ash - 6.7%, acid insoluble ash - 1.039%, water soluble extractive value - 8.88%, alcohol soluble extractive value - 4.49% and pH - 5.75. Preliminary phytochemical study revealed the presence of alkaloids, flavonoids, saponins, triterpenes, tannins, proteins and iron. Rasa Nirdharana confirmed the leaves are Kashaya in Rasa. The Pharmacognostical study was useful for authentication of leaves of Lagerstoemia speciosa.


Author(s):  
Л.Л. ГАНИЖЕВА ◽  
Н.Н. БЕЛИНА ◽  
А.Н. МАТВИЕНКО ◽  
Р.Д. ГАНИЖЕВ ◽  
С.В. НЕГИНА ◽  
...  

Теоретически обосновано создание безалкогольного напитка «Янтарная фея», в состав которого входят янтарная и лимонная кислоты, серебро, а также сухие водорастворимые экстракты семян расторопши и листьев мелиссы. Разработана рецептура безалкогольного напитка «Янтарная фея». Приведены данные, характеризующие органолептические и физико-химические показатели напитка. The theoretical basis for creating a soft drink Amber Fairy is presented. A soft drink Amber Fairy includes amber and citric acids, silver and dry water-soluble extracts of seeds of milk thistle and lemon balm leaves. The recipe of soft drink Amber Fairy is developed. The data characterizing organoleptic and physicochemical parameters of the drink are presented.


2019 ◽  
Vol 5 (2) ◽  
pp. 138-145
Author(s):  
Namadina Muhammad Murtala ◽  
Nuhu Aliyu ◽  
Aliyu Bala Sidi ◽  
Hafizu Muhammad Sulaiman ◽  
Ahmad Abdulkadir Tahir ◽  
...  

Nymphaea lotus belongs to the family Nymphaeaceae and traditionally used in the treatment of aphrodisiac, anodyne, astringent, cardiotonic, sedative, demulcent, analgesic and as anti-inflammatory agent. The objective of the study was to evaluate the phytochemical, physicochemical analysis and safety margin of N. lotus rhizome with the hope of assisting in its standardization for quality, purity and safety. The powdered sample of the rhizome was extracted with aqueous and methanol and evaluated for physicochemical parameters of the plant. The extracts were subjected to qualitative and quantitative phytochemical analysis and acute toxicity study. The physicochemical parameters evaluated include: moisture content (7.4%), total ash (10.3%), water soluble (7.1%), acid insoluble (2.8%), ethanol extractive value (16.7%), and water extractive value (22.0%). The quantitative phytochemical analysis revealed that alkaloids (166.0 mg/g) was the highest phytochemical detected in the rhizome while the lowest was saponins (22.0 mg/g). LD50 of both extracts was above 5000 mg/kg and did not cause mortality in all the tested rats. The results of this finding may be useful in laying down standards and for the compilation of a suitable pharmacopoeia parameters on N. lotus. Asian J. Med. Biol. Res. June 2019, 5(2): 138-145


Author(s):  
Lakshmana Rao A

Objective: To analyze the pharmacognostic characteristics and physiochemical parameters of the root of Eranthemum nigrum (E. nigrum). Methods: Microscopic characters and powder analysis had been carried out with the help of a microscope. The physiochemical properties such as loss on drying, total ash value, acid insoluble ash value, water soluble ash value, extractive values and fluorescence of E. nigrum had been performed. Results: The color, shape, size, odor, and surface characteristics were reported from the root and powdered root material of E. nigrum. Light microscope images of cross section and powdered root revealed the presence of lignified xylem fibers, xylem vessels, cork cells and parenchyma cells. Phytochemical testing confirmed the presence of steroids, alkaloids, tannins, saponins, carbohydrates, glycosides, amino acids and proteins. Physicochemical parameters such as moisture content, ash value, extractive value and fluorescent behavior of root powder have also been established. Conclusion: The morphological, microscopical and physicochemical parameter results provided in this paper may be utilized as a basis for the preparation of a monograph on E. nigrum root.


2019 ◽  
Vol 17 (2) ◽  
pp. 297
Author(s):  
Ahmad Wahyu Hidayat ◽  
Muhammad Iqbal Fasa

This article describes the meaning of education according to Sheikh Nawawi Al-Bantani by using library research and analytical study methods. Analytical studies used are analytical content and analytical descriptions of education according to Sheikh Nawai Al-Bantani. The result of this study indicates that the purpose of education in Islam is a reflection of the function of humans to worship God by achieving His pleasure, striving to eradicate ignorance, and striving to perpetuate Islam with the light of knowledge. His thoughts about educators and students reveal that the personality factor of educators is more important than other factors, whereas, students themselves, they should always hold fast to noble morals in dealing with teachers, both in the teaching and learning process or in interacting with teachers in daily life.Penelitian ini menguraikan pendidikan menurut Syekh Nawawi Al-Bantani. Penelitian ini menggunakan penelitian kepustakaan dengan metode studi analitis. Studi analitis yang digunakan adalah analitis konten dan analitis deskripsi tentang pendidikan menurut Syekh Nawai Al-Bantani.Hasil penelitian ini menunjukkan bahwa tujuan pendidikan dalam Islam merupakan sebuah refleksi dari fungsi manusia untuk beribadah kepada Allah yaitu dengan mencapai keridhoanNya, berjihad untuk memberantas kebodohan, berjihad untuk mengabadikan Islam dengan sinaran ilmu. Pemikirannya tentang pendidik dan peserta didik mengungkapkan bahwa faktor kepribadian pendidik lebih penting daripadafaktor yang lain, sedangkan dengan peserta didik sendiri hendaklah selalu berpegang teguh pada akhlak mulia dalam menghadapi guru, baik dalam proses belajar mengajar ataupun dalam berinteraksi dengan guru dalam kehidupan sehari-hari.


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