scholarly journals Clinical Evaluation of Shilajatu in Madhumeha

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Neha Lamba ◽  
Piyush Chaudhary ◽  
Sharma Y K
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Symptomatic Relief ◽  
Fasting Blood Glucose ◽  
Glycosylated Haemoglobin ◽  
Diabetic Patients ◽  
Laboratory Investigations ◽  
Urine Sugar

The incidence of diabetes mellitus is increasing rapidly because of changes in dietetic habits and life style. Continuous research is being done by scientists of various fields in order to achieve an effective cure of the disease. A great deal of work has also been done by Ayurvedic research scholars on various herbal and mineral drugs to find an effective treatment for Prameha. Shilajatu is one such drug which has been described for the management of Prameha in Ayurveda texts. The present study was conducted to clinically assess the efficacy of Shilajatu in the management of Prameha. Twenty two diabetic patients were selected for the study. The results were assessed in terms of symptomatic relief on the basis of scoring system, laboratory investigations including fasting blood glucose, post prandial blood glucose, glycosylated Hb, urine sugar, and a Questionnaire on Quality of Life. Statistically highly significant improvement (p <0.001) was observed on FBS and PPBS.  Statistically significant improvement was observed on urine sugar and glycosylated haemoglobin with p <0.05 and p<0.01 respectively. In terms of subjective parameters also, highly significant improvement, with p <0.001 was observed in Shaithilya, Mukha Sosha, Sandhi Shoola, Prabhuta Mutrata, Pipasa and Kshudha. Highly significant improvement was observed in quality of life statistically with p <0.001. The study revealed that Shilajatu can be used as a drug in the management of Prameha.

Effectiveness of mobile applications on healthy lifestyles aimed at diabetic patients: review of systematic reviews. (Preprint)

2019 ◽  
Author(s):  
Francisco Jesús Represas Carrera Sr ◽  
Ángel Alfredo Martínez Ques Sr ◽  
Ana Clavería Fontán Sr
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Systematic Reviews ◽  
Mobile Applications ◽  
Control Group ◽  
Diabetic Patients ◽  
Healthy Lifestyles ◽  
Major Public Health Problem

BACKGROUND Diabetes mellitus is currently a major public health problem worldwide. It is traditionally approached in a clinical inpatient relationship between the patient and the healthcare professional. However, the rise of new technologies, particularly mobile applications, is revolutionizing the traditional healthcare model through the introduction of telehealthcare. OBJECTIVE (1) To assess the effects of mobile applications for improving healthy lifestyles on the quality of life and metabolic control of diabetes mellitus in adult patients. (2) To describe the characteristics of the mobile applications used, identify the healthy lifestyles they target, and describe any adverse effects their use may have. METHODS Review of systematic reviews and meta-analysis, following the guidelines of the Cochrane Collaboration and the Joanna Briggs Institute. We included studies that used any mobile application aimed at helping patients improve self-management of diabetes mellitus by focusing on healthy lifestyles. Studies needed to include a control group receiving regular care without the use of mobile devices. In May 2018, a search was conducted in Medline, Embase, Cochrane, LILACS, PsychINFO, Cinahl and Science Direct, updated in May 2019. The methodological quality of the studies was assessed using the Amstar-2 tool. RESULTS Seven systematic reviews of 798 articles were initially selected for analysis. The interventions had a duration of between 1 and 12 months. Mobile applications focused singly or simultaneously on different lifestyles aspects (diet, physical exercise, motivation, blood glucose levels, etc.). There are significant changes in HbA1c values, body weight and BMI, although in others, such as lipid profile, quality of life, or blood pressure, there is no clear improvement. CONCLUSIONS There is clear evidence that the use of mobile applications improves glycemic control in diabetic patients in the short term. There is a lack of evidence in its long-term benefits. It is thus necessary to carry out further studies to learn about the long-term effectiveness of mobile applications aimed at promoting the healthy lifestyles of diabetic patients. CLINICALTRIAL PROSPERO Register: CRD42019133685

scholarly journals Alterations of liver enzymes in T2DM: a case control study

2018 ◽  
Vol 5 (6) ◽  
pp. 1521
Author(s):  
Chandrashekhar G. S.
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Case Control Study ◽  
Liver Enzymes ◽  
Fasting Blood Glucose ◽  
Case Control ◽  
Diabetic Patients ◽  
Histopathological Analysis ◽  
Control Study

Background: Liver plays an important role in regulation of blood glucose in fed state as well as in fasting. Diabetes mellitus can result as a consequence of liver disorder and vice versa. Objective of the present study is to compare the liver enzymes in type 2 diabetic patients as compared to non-diabetic patients.Methods: A case- control study was conducted in Clinical Biochemistry Laboratory, Adarsha Super speciality Hospital, Udupi from April 2018 to August 2018. The data of 174 diabetic patients and 118 healthy people as controls was collected. Fasting blood glucose, aspartate aminotransferase (AST), alanine amino transferase (ALT) and alkaline phosphatase (ALP) were estimated in the study subjects.Results: It was found that AST levels (47.55±4.69U/L) in diabetics extremely significantly high as compared to controls (33.51±2.33U/L). ALT levels were insignificantly high in diabetics compared to controls. ALP was significantly elevated (p=0.0002) in diabetics. Correlation study showed a weak positive correlation between AST, ALT and blood glucose. Odds ratio showed a higher risk of liver enzyme elevation in diabetics. Risk of elevation of AST was found to be 1.65 times high and ALT was 1.25 times high in diabetics compared to non-diabetics.Conclusions: Diabetics had high liver enzymes as compared to non-diabetics. An association was found between type 2 diabetes mellitus and liver enzymes. For better characterization of cause and effect, further studies need to be done on alterations in liver function tests along with the histopathological analysis of liver biopsy samples.

scholarly journals Quality of Life in Type 2 Diabetic Patients

2014 ◽  
Vol 31 (3) ◽  
pp. 193-200 ◽  
Author(s):  
Ana Spasić ◽  
Radmila Veličković Radovanović ◽  
Aleksandra Catić Đorđević ◽  
Nikola Stefanović ◽  
Tatjana Cvetković
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Short Form ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Cross Sectional ◽  
Significant Difference ◽  
Type 2 Diabetic

Summary The presence of diabetes mellitus leads to a decrease in life quality in all domains. The aim of our study was to evaluate the quality of life (QOL) in diabetic patients and the factors affecting it in type 2 diabetic mellitus patients. We conducted a cross-sectional study that included 86 patients with type 2 diabetes mellitus, in the territory of the City of Niš. Health-related QOL of patients was measured using the short form survey (SF-36) that produces an 8-scale health profile. The average duration of diabetes was 12.76±8.08 years. The best QOL in all areas was observed in patients diagnosed with diabetes less than 10 years ago p<0.05) and younger than 65 years. Male respondents perceived a better QOL compared to women, especially in the vitality and pain domains. The patients with comorbidity (93.64%) had lower QOL score in all domains. There was no significant difference in the QOL of patients with diabetes compared to the level of education. High QOL represents an ultimate goal and an important outcome of all medical interventions in diabetic patients. Factors related to lower QOL included: older age, female gender, and existence of comorbidities. Uncontrolled diabetic patients had a lower QOL than controlled diabetics.

The Effect of Biochanin A as PPAR γ agonist on LDL Particles Diameter and Type 2 Diabetic Dyslipidemia

2019 ◽  
Author(s):  
Darya Ghadimi ◽  
Mohammad Taghi Taghi Goodarzi ◽  
Mahdi Bahmani ◽  
Zohre Khajehahmadi
Keyword(s):  
Diabetes Mellitus ◽  
Body Weight ◽  
Blood Glucose ◽  
Fasting Blood Glucose ◽  
Male Rats ◽  
Biochanin A ◽  
Diabetic Patients ◽  
Low Density ◽  
Diabetic Dyslipidemia ◽  
Ldl Particles

Background and Aims: Small dense  low-density lipoproteins (sd-LDL) particles are smaller and heavier than typical LDL ones. They can penetrate into the endothelium of coronary arteries more easily because of their small size. Diabetes mellitus is accompanied by dyslipidemia such as increasing concentration of plasma very low density lipoprotein and sd-LDL. Peroxisome proliferator activated receptor γ (PPARγ ) can decrease the level of sd-LDL in plasma. Biochanin A (BCA), a natural compound, is a PPARγ agonist. The present study was designed to investigate the effect of BCA on sd-LDL-Clolesterol level in diabetic animals. Materials and Methods: Adult male rats (Wistar strain) were used as the animal models in this study. Animals were made diabetic by single intraperitoneal injection of Streptozotocin- Nicotinamide and then treated by 1 and 5 mg/kg of BCA for 28 days. Body weight and fasting blood glucose were also tested before and at the end of treatment. Furthermore, the size of LDL particles were measured by nondenaturing polyacrylamide gradient gel electrophoresis assay. Results: Results of the present study indicated that BCA administration at dose of 5mg/kg decreased fasting blood glucose level and increased body weight and diameter of LDL particles in diabetic animals significantly. Conclusions: BCA seems to be an appropriate agent in diabetes mellitus, because it improves the diabetic dyslipidemia, which is the most important complication in diabetic patients.

scholarly journals CENTER BASED VERSES TELE-REHABILITATION FOR DIABETES MELLITUS

2021 ◽  
Vol 5 (1) ◽  
pp. 190-191
Author(s):  
Saira Waqar ◽  
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Health Care ◽  
Foot Ulcers ◽  
Diabetic Patients ◽  
Rehabilitation Center ◽  
Rehabilitation Programs ◽  
Practice Models ◽  
At Home

Globally, new trends of practices are incorporating in health care sector, academics as well as in our daily lives to cope with the current population need. It is much needed to develop and implement new sophisticated practice models in rehabilitation to treat the different clinical conditions. Diabetes mellitus is one among the top 10 causes of death, with significant increase of 80% since year 20001. As estimated by International Diabetes Federation worldwide, 425 million people are suffering with diabetes mellitus.2 Diabetic neuropathy is one of highly prevalent condition which substantially affects patients by increasing frequency of falls, neuropathic pain and low quality of life (QOL).Diabetic patients suffer with following complaints i.e. Foot ulcers that develops due to peripheral vascular ischemia and poor pressure distribution on plantar surface of foot which increases the risk of fall due to loss of balance and disturbance in gait patterns.3 Total 20% of foot ulcers need an amputation wherein patients further suffer with secondary complications which in turn builds massive economic burden on health care system.4 The rehabilitation combined with diet and medications has proven as an effective method to treat diabetes and its neuropathy symptoms. Supervised conventional center based physical activity training programs are generally in practice to treat this metabolic condition. Though clinical effectiveness of these programs is established on clinical outcomes, with reduction in mortality rate, despite all the benefits of rehabilitation programs, very low patient attendance is observed in hospital based supervised rehabilitation programs. The regularity in exercise along with dietary intervention and fixed medication monitoring is the key component to manage diabetes. But high drop-out levels negatively affects the proven effectiveness of rehabilitation. There are different aspects for this low level of participation i.e. lack of time, approachability of a program, home bound work or obligations and psychological barriers etc. Therefore, new practice models are essential to improve the rate of participation on regular basis in these exercise program.5 Computer based technological incorporation in the field of health is evolving dramatically as a promising tool in improving quality of life cost effectively. It can also help us to achieve WHO goal “to improve access to health care services and professionals”. Tele-rehabilitation may prove effective as part of the rehabilitation program, especially for diabetic patients who fail to participate in conventional rehabilitation center-based programs due to domestic issues. The factors associated with suboptimal participation in rehabilitation at home are less prevalent. In tele-rehabilitation, patients are not bound to visit rehabilitation center or hospital; hence they have the freedom to perform exercise at home. But the limitations in utilization of this approach are: patient assessment and evaluation in a structured manner, monitoring the effect of program on regular basis, suitability of approach for all type of morbidities & severity levels of diabetes and suitable equipment having required features for patients as well as practitioners.6 Tele-rehabilitation is a prospective opportunity to treat the diabetic patients through regular monitoring with less drop outs rather than center based approach. However, there is a need to identify the types and severity of diabetic patients for whom this approach is safe and effective. Secondly, it is required to define clinical assessment outcomes which can be monitored and assessed. Incorporation of advanced equipment and relevant operational training is indispensable. Development of Standardized documentation for patient evaluation, intervention and outcomes monitoring is imperative to long term sustainability and improvement of practice. It is equally important to ensure the security and confidentiality of Patient’s personal data and privacy.7

scholarly journals Harapan Pada Lansia Dengan Diabetes Melitus Tipe 2

2020 ◽  
Vol 7 (2) ◽  
pp. 97
Author(s):  
Lailatuz Zalia Ifianti ◽  
Rita Hadi Widyastuti
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Sampling Technique ◽  
The Elderly ◽  
Diabetic Patients ◽  
Validity And Reliability ◽  
Herth Hope Index ◽  
High Level ◽  
Diabetes Melitus

Diabetes melitus adalah gangguan metabolik yang ditandai dengan kenaikan kadar glukosa dalam darah dan dapat menyebabkan  berbagai macam komplikasi sehingga mempengaruhi kualitas hidup lansia. Harapan akan membawa kepada keoptimisan dan meningkatkan kualitas hidup lansia dengan penyakit kronis. Sementara penelitian mengenai dampak harapan masih sangat kurang. Penelitian ini bertujuan untuk mendeskripsikan derajat harapan pada lansia dengan diabetes melitus tipe 2.Penelitian ini menggunakan desain penelitian kuantitatif survei, responden terdiri dari 127 lansia yang menderita DM tipe 2 yang diambil dengan teknik total sampling setelah memenuhi kriteria inklusi. Kuesioner HHI (Herth Hope Index) digunakan untuk mengetahui gambaran harapan. Uji validitas dan reliabilitas telah dilakukan dan hasilnya valid serta reliabel.  Hasil penelitian ini menunjukkan bahwa karakteristik responden adalah didominasi usia 60-74 tahun, sebagian besar berjenis kelamin wanita, tingkat pendidikan didominasi oleh pendidikan SD-SMP, sebagian besar menikah, Suku Jawa, menderita DM < 5 tahun dan tidak mengalami komplikasi. Derajat harapan menunjukkan bahwa responden mempunyai harapan yang tinggi dengan nilai mean sebesar 37.41. Sebagian besar responden merasa hidupnya memiliki nilai dan berharga.Masyarakat dan petugas kesehatan harus membantu lansia mempertahankan derajat harapan yang sudah tinggi dengan menyediakan dukungan sosial dan membantu lansia mencari jalan keluar ketika menghadapi masalah tentang kesehatan dan yang lainnya. Kata Kunci: diabetes mellitus; harapan; lansiaHOPE IN ELDERLY WITH DIABETES MELITUS TYPE 2Diabetes mellitus is a metabolic disorder that signed with the increase of glucose level in blood and can make various complication which influences the elderly’s quality of life. Hope will bring the optimism and increased the  quality of life on elderly with chronic diseases. However, research supporting this effect is lacking. This study was aimed to find out the description of the hope level among elderly with diabetes mellitus type 2. This study was quantitative descriptive with 127 elderly diabetic patients taken by using total sampling technique by fulfilling the inclusion criteria. Herth Hope Index (HHI) questionnaire was used. The validity and reliability was confirmed. The results of this research show that the age of respondent was dominated with 60-74 years old, mostly consist of female. The education level was mostly elementary school, mostly have been married and from Javanese family, suffered from DM for about 5 years and mostly didn’t have complications. For the hope level, the respondent mostly  is in high level with mean score is 37.41. The respondent feel that their life is worth and precious. Based on the results of this research, the society and health center member should help the elderly to maintenance their level of hope by give the support system to the elderly and facilitate the elderly to solve their problem about health or another. Keywords: diabetes mellitus; elderly; hope  

scholarly journals Relationship Between Family Support and Self Care Agency with the Quality of Living Type II Diabetes Patients

2019 ◽  
Vol 3 (1) ◽  
pp. 22-32
Author(s):  
Ferawati ◽  
Mei Fitria Kurniati
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Family Support ◽  
Type Ii Diabetes ◽  
Self Care ◽  
P Value ◽  
Diabetic Patients ◽  
Type Ii ◽  
Care Agency

Background: Diabetes Mellitus is a chronic disease characterized by high blood sugar level and is caused by an increase in glucose levels due to a progressive decrease in insulin secretion caused by insulin resistance. The ability of diabetic patients to do appropriate and succesful self-care habits is closely related to morbidity and mortality and significantly affect productivity and quality of life. Purpose: The purpose of this study is to determie the correlation between family support and self care agency with quality of life of diabetes mellitus patient type II.Method: This study uses analitycal methods, namely research that explores how and why health phenomena occur with a cross-sectional approach.Result: The results of the Spearman-Rho test that the P-value in te sig (2-tailed) column 0.123 is more than the level of significance α 0,05 ( 0,000 < 0,05 ) so it can be concluded that H0 is accepted and H1 is rejected.Conclusion: There is no relationship between self care agency and the quality of life of people with type II diabetes mellitus in prolanic patients

Sign in / Sign up

Export Citation Format

Share Document