The Biophysical Modeling of the Respiratory Apparatus in the Human Organism

2020 ◽  
Vol 01 (02) ◽  
Author(s):  
Janos Vincze ◽  
Gabriella Vincze-Tiszay
Keyword(s):  
Human Organism ◽  
Biophysical Modeling ◽  
Respiratory Apparatus

The Biophysical Modeling of the Hemodynamic in the Human Organism

2020 ◽  
Vol 7 (11) ◽  
pp. 494-502
Author(s):  
Janos Vincze ◽  
Gabriella Vincze-Tiszay ◽  
Julianna Szakacs
Keyword(s):  
Blood Flow ◽  
Vascular System ◽  
Experimental Testing ◽  
Real Life ◽  
Pathological Process ◽  
Human Organism ◽  
Main Function ◽  
Biophysical Modeling ◽  
Circulatory Apparatus ◽  
Cardio Vascular

The circulatory apparatus has as a main function the constant maintaining of the internal environment in all the regions of the organism. The blood is a liquid tissue, being formed of a fundamental substance – plasma and blood cells. Heart is the central organ of the cardiovascular apparatus. The heart muscles have numerous biophysical properties. The cardiac muscle is never tired unless it suffered a pathological process. During the diastole, blood is aspired in the heart and during the systole it is pushed in the big and small circulation. The blood amount pushed from the heart in the vascular system in a certain time represents the blood flow. The biophysical methods are next: we administer a certain substance amount, then its passing speed will depend on its concentration; to apply the calorimetric principles for the measurement of the gastric blood flow; the diagnostic of a chronic peripheral arteriopathy we use the calorimetric method is based on measuring the heat being introduced in a certain amount of water which has known temperature; one of the most often used methods for the evaluation of the use of radioisotopes in the cardio-vascular system is the compartment method. Any attempt to apply biophysics to the life systems involves three stages. First we observe the phenomena and formulate a biophysical description in the form of equations; after to solve the equations. Finally we return to the real life system and interpret this solution in terms of reality, this interpretation may requiew experimental testing.

scholarly journals The Biophysical Modeling of the Rhythmical Periods in the Human Organism

2020 ◽  
Vol 5 (4) ◽  
Keyword(s):  
Periodic Function ◽  
Menstrual Period ◽  
Human Organism ◽  
Human Adaptation ◽  
Deep Breathing ◽  
Biophysical Modeling ◽  
Material Models ◽  
Functional Systems ◽  
Contraction And Relaxation ◽  
Respiratory Movements

Biophysics uses certain devices to help it study the processes analogue to the ones that happen in the biological systems, hence material models. The importance on biophysics consists of the fact that a model for a simpler system gives the possibility to a certain extent to apply the same model to more complex functional systems as well (for example the organism). The respiratory movements are rhythmical and automatic: in an adult at rest is between 16 and 18 per minute. We write a periodic function for the deep breathing. So, the contraction and relaxation of the atrium and ventricle, are characterized by a periodic function. The menstrual period is a rhythmical pheno¬menon. The optimal systems ensure the coincidence between the regulated size and the reference one through negative retroaction, compensating the perturbation. The rhythmical phenomena are a very import role in human adaptation to the environment.

scholarly journals The Psycho-biophysical Modeling of the some Stress Parameters

2020 ◽  
Vol 7 ◽  
pp. 201-208
Author(s):  
Janos Vincze ◽  
Gabriella Vincze-Tiszay
Keyword(s):  
Negative Feedback ◽  
Immune Regulation ◽  
Human Organism ◽  
Biophysical Modeling ◽  
Normal Reaction ◽  
Action Preparation ◽  
Living Organisms ◽  
Short Time ◽  
Stress Parameters ◽  
Biophysical System

The human organism is a biophysical system. Stress represents a normal reaction of the organism which appears as a response to an aggression situation which requires an unusual and quick adaptation effort from the organism. Stress is a state of putting in alert, of mobilizing the forces of the organism in the occasion of an event which requires, in order to be kept under control, a big amount of energy in a very short time. This alert state or action preparation translated through physical and psychological manifestations. In higher-level living organisms the following forms of regulation are known: biological, nervous, hormonal, humoral and immune regulation. In the case of humans, psychic regulation also appears due to the existence of psychic activity. We study only two forms of the stress: fear and death. We present different biophysical modeling aspects. The stress in the human organism is a pertur­bation. This perturbation is regulates by negative feedback.

scholarly journals Challenges to Breastfeeding among Women Attending the Infant Welfare Clinic in a Selected Primary Health Care Center In Lagos, Nigeria

2020 ◽  
pp. 1-8
Author(s):  
Flo Folami ◽  
Keyword(s):  
Health Care ◽  
Primary Health Care ◽  
Care Center ◽  
Simultaneous Action ◽  
Human Organism ◽  
Biophysical Modeling ◽  
Health Care Center ◽  
Infant Welfare ◽  
Primary Health ◽  
Living Organisms

The transport phenomena mean the variation in time and space of generalized forces when they generate flows for which conservation laws apply. After we describes: mass-, impulse-, energy- and electric-charge-transport and their mathematical characteristic equations. In the living organisms, flows are not generated only by the conjugated generalized forces, but also by the simultaneous action of other forces, so frequencies of the crossing-effects in the human organism. The biophysical modeling offer a „language” of quantitative and qua¬litative process¬sing of expe¬rimental data, being compatible and adequate to the laws of biology.

scholarly journals The Biophysical Modeling of Crossing-Effects in Living Organisms

2020 ◽  
pp. 1-3
Author(s):  
Janos Vincze ◽  
◽  
Gabriella Vincze-Tiszay ◽  
Keyword(s):  
Conservation Laws ◽  
Charge Transport ◽  
Electric Charge ◽  
Transport Phenomena ◽  
Simultaneous Action ◽  
Human Organism ◽  
Biophysical Modeling ◽  
Time And Space ◽  
Characteristic Equations ◽  
Living Organisms

The transport phenomena mean the variation in time and space of generalized forces when they generate flows for which conservation laws apply. After we describes: mass-, impulse-, energy- and electric-charge-transport and their mathematical characteristic equations. In the living organisms, flows are not generated only by the conjugated generalized forces, but also by the simultaneous action of other forces, so frequencies of the crossing-effects in the human organism. The biophysical modeling offer a „language” of quantitative and qua¬litative process¬sing of expe¬rimental data, being compatible and adequate to the laws of biology.

Some Biophysical Modeling of the Human Circulation Apparatus

2020 ◽  
Vol 3 (8) ◽  
Author(s):  
Janos Vincze ◽  
Gabriella Vincze- Tiszay
Keyword(s):  
Circulatory System ◽  
Work Capacity ◽  
Human Organism ◽  
Biophysical Modeling ◽  
System Disease ◽  
Control Functions ◽  
Global Trend ◽  
Circulatory Apparatus ◽  
Peripheral Arterial ◽  
Contraction And Relaxation

Statistics from Hungary over the last seven years clearly show that diseases of the circulatory device lead the statistics on the causes of death. The Hungarian trend is the same as the global trend, with circulatory system disease being the most common cause of death in every country. The modeling of the blood volume, if we administer a certain substance amount, then its passing speed will depend on its concentration, hence the volume at which it spreads in the deposit. Consider the contraction and relaxation of the atrium/ventricle of the human heart; use the function of the rhythmic change for this. We apply the calorimetric principles for the measurement of the gastric blood flow. In the physio­pathology research of the circulation in arteriopathic people, when there are necessary arguments refering to the efficiency of new medicines or for the purpose of reestablishing the work capacity, the clinic diagnostic must be completed with laboratory samples: regional debt, peripheral arterial resistance, circulation time. Its measuring can be made with a normal double walls calorimeter and we measure the water temperature variations. Knowing the values of the previous formulas and the mass of blood circulated in that segment, we find out the segment’s flow. The human organism is a system because it is made up of a finite number of interacting p1, p2,… pn elements, characterized by the quantitative degree of q1, q2,… qn. The circulatory apparatus is a subsystem of the human body. In our opinion, the circulatory device should have a control associated with its own structure, which is likely to consist of neurons with hyperordonated spatial structure, called the “hypothetical secondary brain”, which performs certain control functions. This “hypothetical secondary brain” of the circulatory apparatus, in humans, functions continuously throughout their life.

scholarly journals Some Stress Aspects from Psycho-biophysical Point of View

2020 ◽  
Vol 5 (4) ◽  
Keyword(s):  
Medical Science ◽  
Point Of View ◽  
Physiological Parameter ◽  
Human Organism ◽  
Experimental Medicine ◽  
Biophysical Modeling ◽  
Wide Range ◽  
Psychological Balance ◽  
Main Entrance ◽  
Qualitative Changes

Selye published his famous theory of the stress in Nature in 1936. For the stress motto is the inscription at the main entrance of the Institute of Experimental Medicine and Surgery (Montreal): “Neither the prestige of your subject, and the power of your instruments, nor the extent of your learned¬ness and the precision of your planning, can substitute for the originality of your approach and the keenness of your observation.” The stress in the human organism is a perturbation. This perturbation is regulates by negative feedback. All physiological parameters characterizing the organism oscillate between a minimum and maximum value. The stress is properly a general adaptational answer rised under the influence of some stressor, with characteristic but not specific changes. The organism can, in general, get along namely by switching on also another regulatory mechanism for the convienent control of the altered physiological parameter. All these surplus regulations need excees-energy from the side of the organism, contribute to wear it and for this very reason accelerate the process, of aging. We use the Le-Chatelier principle and determine the measure of psychical organization. For the all laboratorial parameters exists five zones: optimum (1), admissible (2a., 2b.), dangerous (3a., 3b.), inactivity (4a., 4b.) and inviability (5a., 5b.). As a conclusion, the present medical science reserves the word perinormal for naming biophysical, biochemical and physiological responses in a wide range that warn us referring to the existence of mainly quantitative or reversible qualitative changes and the possibility of irreversibly pathological qualitative alterations. We presented of the biophysical modeling of the creativity and talk over the psychological balance of the man.

scholarly journals The Biophysical Modeling of the Sleep Regulation in the Human Organism

2021 ◽  
Vol 2 (4) ◽  
pp. 01-04
Author(s):  
Janos Vincze ◽  
Gabriella Vincze-Tiszay
Keyword(s):  
Slow Wave Sleep ◽  
Paradoxical Sleep ◽  
The Other ◽  
Human Organism ◽  
Biophysical Modeling ◽  
Sleep Regulation ◽  
Sleep Period ◽  
Slow Sleep ◽  
Eeg Recordings ◽  
The Individual

A seventy-year-old human spends approx. twenty years, or one-third of their life, asleep. During sleep, their connection with the outside world is more or less lost, but in the meantime they experience exciting dreams that are difficult for rational thinking to grasp. Analysis of EEG recordings revealed that sleep can be divided into two sharply separated states: one is the so-called slow wave sleep; the other is the so-called paradoxical sleep (REM), e.g. characterized by strong eyeball movement. The slow sleep period can be divided into 4 periods based on the EEGs, and these follow each other in a well-defined order, then comes the paradoxical sleep and the whole thing is repeated; during a full sleep of approx. 4–6 times. The duration of paradox sleep depends on the individual, but it lasts for approx. 6–15 minutes. Compared to the literature, one of the significances of this article is also that we wrote a mathematical model of the sleep. This model also allows us to characterize different forms of particular sleep.

The limits of human performance

2008 ◽  
Vol 44 ◽  
pp. 11-26 ◽  
Author(s):  
Ralph Beneke ◽  
Dieter Böning
Keyword(s):  
Human Performance ◽  
Safety Margin ◽  
Afferent Input ◽  
Metabolic Energy ◽  
Human Organism ◽  
Mechanical Resistance ◽  
As Doping ◽  
Gene And Protein Expression ◽  
Underlying Mechanisms ◽  
Biochemical Research

Human performance, defined by mechanical resistance and distance per time, includes human, task and environmental factors, all interrelated. It requires metabolic energy provided by anaerobic and aerobic metabolic energy sources. These sources have specific limitations in the capacity and rate to provide re-phosphorylation energy, which determines individual ratios of aerobic and anaerobic metabolic power and their sustainability. In healthy athletes, limits to provide and utilize metabolic energy are multifactorial, carefully matched and include a safety margin imposed in order to protect the integrity of the human organism under maximal effort. Perception of afferent input associated with effort leads to conscious or unconscious decisions to modulate or terminate performance; however, the underlying mechanisms of cerebral control are not fully understood. The idea to move borders of performance with the help of biochemicals is two millennia old. Biochemical findings resulted in highly effective substances widely used to increase performance in daily life, during preparation for sport events and during competition, but many of them must be considered as doping and therefore illegal. Supplements and food have ergogenic potential; however, numerous concepts are controversially discussed with respect to legality and particularly evidence in terms of usefulness and risks. The effect of evidence-based nutritional strategies on adaptations in terms of gene and protein expression that occur in skeletal muscle during and after exercise training sessions is widely unknown. Biochemical research is essential for better understanding of the basic mechanisms causing fatigue and the regulation of the dynamic adaptation to physical and mental training.

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