Discussion on the Development and Strategy of New Chemical Materials

2021 ◽  
Keyword(s):  
Author(s):  
Fatima Abdul Hussein Mejbel

 During the period from September 2016 to December 2017,135 urine samples were collected from urinary tract infection patients attending to AL-Zahraa Hospital in AL-Najaf Governorate. The present study was conducted to isolate and identify Candida spp. isolated from urinary tract infection patients by different methods including direct examination, laboratory culture, biochemical test and by modern techniques (Api Candida kit) and determine the virulence factors phenotypic to Candida spp which involved (biofilm formation,phospholipase and germ tube). The percentage of females to males was as following, female (84) 62.2 % (21) infected and male (51) 37.8% (1) infected with all age categories. The results in this study are explain that is some Candida spp. such as C. albicans, have high susceptible to eugenole follow by phenol and umbellulone. The efficiency of some chemical substances such as (eugenole,umbellulone, and phenol) was evaluated to inhibit the growth of Candida ssp as well as some virulence factors such as biofilm formation,germ tube and phospholipase,which were studied in this research. Statistically analysis results have been significance difference between the results of the substance concentrations and the concentrations of the different other substances.


2015 ◽  
Author(s):  
Stephanie Farrell ◽  
Stephen Krause ◽  
Nancy Ruzycki ◽  
Amber Genau ◽  
Brittany Nelson-Cheeseman ◽  
...  

Author(s):  
Vadim Valer’evich Kashin ◽  
Vladimir Vladimirovich Kolesov ◽  
Iren Evgenievna Kuznetsova ◽  
Eugenii Sergeevich Soldatov ◽  
Yulia Victorovna Plekhanova ◽  
...  
Keyword(s):  

2021 ◽  
Vol 6 (2) ◽  
pp. 93-104
Author(s):  
Aisyah Amini ◽  
Riri Okra

ALKI is an e-module that serves as a learning medium for grade X students majoring in MIA at SMAN 1 MAPAT TUNGGUL. E-module ALKI was created with the aim of assisting teachers in delivering materials and helping students understand more about chemical materials by repeating lessons, working on exercises, and strengthening memory by playing flashcards. The thing behind the design of alki e-module is the lack of motivation to learn students, difficulty and the absence of internet network in Mapat Tunggul area, students should not take home the package book, the smartphone owned by students is not used to study, and when doing homework with the help of the internet most students just copy the answer without understanding the origin of the answer. This research method is Research and Development (R&D) with a 4-D research model (four-D) that is with define, Design, Development, and Disseminate stages. In the Development stage, the development stage of ALKI e-module media is carried out. The media development model used in this study is MDLC(Multimedia Development Life Cycle) luther-sutopo version which consists of 6 stages, namely conception, design, material collection, manufacturing process, testing and distribution. The result of the research is a mobile-based ALKI e-module product. With 0.81 validity test results declared valid,0.93 Practicality test results are practiced very practically,and 0.80 effectiveness test results are declared very effective. So, it can be concluded that alki e-module based on mobile application as a learning medium has been valid, practical and effective.


2020 ◽  
Author(s):  
Xinzhe Zhu ◽  
Chi-Hung Ho ◽  
Xiaonan Wang

<p><a></a><a>The production process of many active pharmaceutical ingredients such as sitagliptin could cause severe environmental problems due to the use of toxic chemical materials and production infrastructure, energy consumption and wastes treatment. The environmental impacts of sitagliptin production process were estimated with life cycle assessment (LCA) method, which suggested that the use of chemical materials provided the major environmental impacts. Both methods of Eco-indicator 99 and ReCiPe endpoints confirmed that chemical feedstock accounted 83% and 70% of life-cycle impact, respectively. Among all the chemical materials used in the sitagliptin production process, </a><a>trifluoroacetic anhydride </a>was identified as the largest influential factor in most impact categories according to the results of ReCiPe midpoints method. Therefore, high-throughput screening was performed to seek for green chemical substitutes to replace the target chemical (i.e. trifluoroacetic anhydride) by the following three steps. Firstly, thirty most similar chemicals were obtained from two million candidate alternatives in PubChem database based on their molecular descriptors. Thereafter, deep learning neural network models were developed to predict life-cycle impact according to the chemicals in Ecoinvent v3.5 database with known LCA values and corresponding molecular descriptors. Finally, 1,2-ethanediyl ester was proved to be one of the potential greener substitutes after the LCA data of these similar chemicals were predicted using the well-trained machine learning models. The case study demonstrated the applicability of the novel framework to screen green chemical substitutes and optimize the pharmaceutical manufacturing process.</p>


2017 ◽  
Vol 2 (2) ◽  
pp. 137
Author(s):  
Izzatyl Zakiah

This study aims to determine student learning outcomes through the implementation of Learning Strategies Enhanced Thinking Skills (SPPKB) the text of the study subjects high school chemistry curriculum and student activities in developing chemical materials


e-Polymers ◽  
2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Joseph Jagur-Grodzinski

AbstractProperties of the electrically conductive polymers (ECPs) enable introduction of several novel applications in various fields, among others, as biomedical materials. Their use as scaffolds for tissue engineering and recovery of damaged neural tissues is especially advantageous. They may also be used for the electrically induced drug release and delivery, and as very sensitive biosensors for clinical applications. Another use is the detection and precision of the biologically important chemical materials. They have been shown to modulate and accelerate activities of the nerve, skeletal, muscle, and bone cells. Cell growth, migration and adhesion, may be stimulated by applying electric potential. Synthesis of DNA, secretion of proteins, and transformations of stem cells may be enhanced. Clinical analysis using ECP-based biosensors make possible the precise determination of the exact composition of individual DNA molecules, and thus enable early detection and treatment of genetically related diseases. Electrochemical (EC) approach of ECP-sensors enables precise determination of concentrations of several biologically important chemicals.


Author(s):  
Jeganathan Muthaiyan ◽  
Mohammed Saleh Nusari ◽  
Vasanthy Muthunarayanan

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