Analysis of field free region formed by parametric positioning of a magnet pair for targeted magnetic hyperthermia
One of the challenges that arise in the practical applications of magnetic fluid hyperthermia (MFH) is the limited control of magnetic nanoparticle oscillations. In this study, we investigated to manipulate field free region (FFR) form and location by symmetric and asymmetric displacements of a magnet pair (MP). Finite element method (FEM) simulation was used to predict gradient patterns (GPs) in the workspace. An experiment platform was produced and point probe measurements are taken. It is observed that FFR form and position can be manipulated with parametric distance and angle changes. FFR can shrink and its form can be transformed to the linelike or point-like areas. Focus of FFR can be moved off-center, and it can be directed to different parts of the target object. The mapping of GP produced by a MP for the use of targeted MFH is discussed for the first time in this study. And the findings provide insight into which GP is appropriate in which situations in targeted MFH.