Comparative Anti-plaque and Anti-gingivitis Efficacy of Two Commercially Available Mouthwashes - 4 Weeks Clinical Study

2011 ◽  
Vol 5 (3) ◽  
pp. 110-112 ◽  
Author(s):  
Geetanjali Sikka ◽  
KT Chandrashekar
Keyword(s):  
Clinical Study ◽  
Test Group ◽  
Plaque Index ◽  
Control Group ◽  
Isopropyl Myristate ◽  
Gingival Health ◽  
Mouth Rinses ◽  
Sodium Saccharin ◽  
Dual Action ◽  
Oral Hygiene Instructions

ABSTRACT Therapeutic mouthwashes are often recommended as an adjunct to mechanical plaque control for prevention of plaque formation and maintain gingival health. The present clinical study was for the duration of four weeks and focused on two specific mouthwashes: HEXIDINE (0.2% chlorhexidine) and SEFDENT (a dual action mouthrinse with clove oil and sorbitol, sol isopropyl myristate, sodium saccharin) both claims to be effective in the treatment of gingivitis. HEXIDINE (Chlorhexidine) has long-standing research to substantiate its safety and efficacy whereas the SEFDENT mouthwash used in this study is a new mouthwash with many components in it. Subjects were randomly allocated into either the test group (n = 10,Sefdent) or the control group (n= 10,Hexidine) Plaque levels were measured using the Turesky's modification of the Quigley & Hein Plaque Index (PI), and gingivitis was evaluated and recorded with the Gingival Index (Loe and Silness 1963) (GI) at 0 day, 15th days and 30th day. All Subjects were instructed with oral hygiene instructions. First scaling and root planning was performed on all subjects and then they were asked to rinse twice daily with one of the mouthwashes (HEXIDINE or SEFDENT). Both the mouth-rinses studies turned out to be statistically significant but control group (HEXIDINE) showed significant improvement in plaque index, gingival scores, when compared to test group (SEFDENT). This shows that chlorhexidine remains a gold standard in improving the gingival status.

scholarly journals EFFECT OF HERBAL TOOTHPASTE CONTAINING NEEM LEAVES EXTRACT (AZADIRACHTA INDICA) AGAINST GINGIVITIS: A CLINICAL STUDY

2019 ◽  
pp. 117-119
Author(s):  
AMELIA PRISCILLA SUGIARTA ◽  
ROBERT LESSANG ◽  
NATALINA .
Keyword(s):  
Clinical Study ◽  
Oral Cavity ◽  
Azadirachta Indica ◽  
Test Group ◽  
Tooth Brushing ◽  
Plaque Index ◽  
Control Group ◽  
Leaf Extracts ◽  
Neem Leaves ◽  
And Control

Objective: Neem leaves are known to have antibacterial, anti-inflammatory, antifungal, antiseptic, antitumor, antihyperglycemic, antiulcer, andantiviral effects. In addition, they can reduce the counts of plaque-forming bacteria in the oral cavity. This study aimed to evaluate the effect of anherbal toothpaste containing neem leaves extract against gingivitis.Methods: A total of 40 subjects were divided into two groups (n=20 each): Experimental and control. Those in the test group were instructed to brushtheir teeth twice a day for 7 days with neem leaves extract toothpaste, whereas the control group subjects were asked to continue with the non-herbalpaste they used for tooth brushing. Plaque index (PI) and papillary bleeding index (PBI) were measured on day 0 and day 7.Results: Significant reductions in PI and PBI were noted between the test and control groups.Conclusion: The findings of this clinical study provide evidence that neem leaf extracts are effective in reducing gingivitis.

scholarly journals Treatment Success and User-Friendliness of An Electric Toothbrush App: A Pilot Study

2020 ◽  
Vol 8 (3) ◽  
pp. 97
Author(s):  
Viviane Humm ◽  
Daniel Wiedemeier ◽  
Thomas Attin ◽  
Patrick Schmidlin ◽  
Stefanie Gartenmann
Keyword(s):  
Pilot Study ◽  
Treatment Success ◽  
Test Group ◽  
Plaque Index ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
User Friendliness ◽  
Short Period ◽  
Electric Toothbrush ◽  
And Control

Electronic and mobile health (eHealth/mHealth) are rapidly growing areas in medicine and digital technologies are gaining importance. In dentistry, digitalization is also an emerging topic, whereby more and more applications are being offered. As an example, using real-time feedback, digital application software (an app) was designed to help users brush their teeth more accurately. However, there is no data on the effectiveness and haptic of such apps. Therefore, a single-blinded, randomized controlled clinical trial was designed: twenty volunteers received an electric toothbrush with an associated app to assess whether the app-assisted toothbrushing is better than without. After a short period of familiarization with the electric toothbrush, plaque index (O‘Leary et al. 1972) was recorded and subjects were assigned to the test (with app; n = 10) or the control group (no app; n = 10). At the end of the 2-week pilot study period, plaque was again assessed and participants in the test group completed a questionnaire about the app’s user-friendliness. Statistical analysis revealed no significant differences between the test and control groups. The plaque index improved on average by 8.5% points in the test and 4.7% points in the control group. Fifty percent of the test group participants were of the opinion that they had achieved better cleaning results and would recommend the app to others, although the app contributed only marginally to increased plaque removal. However, such apps may nevertheless be helpful as motivational tools, especially when tracking and monitoring cleaning data. Therefore, more development and research on this topic is indicated.

scholarly journals Oral Hygiene in a Sample of Children/Adolescents Living in Family-Homes from the Province of Milan (Italy): A Pilot Study

2020 ◽  
Vol 8 (2) ◽  
pp. 33 ◽  
Author(s):  
Alessandro Nota ◽  
Floriana Bosco ◽  
Shideh Ehsani ◽  
Francesca Giugliano ◽  
Giulia Moreo ◽  
...  
Keyword(s):  
Pilot Study ◽  
Oral Hygiene ◽  
Clinical Results ◽  
Plaque Index ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Study Group ◽  
Significant Difference ◽  
And Gender ◽  
Oral Hygiene Instructions

Objective: This pilot study is a prospective controlled clinical trial, designed to evaluate the short-term clinical results (the plaque index) of an educational/motivational program for home oral hygiene, directed to children and adolescents who live in family-homes. Methods: The setting of the project was the province of Milan (Italy), where two family-homes were selected. The study group included 26 children (16 females and 10 males) aged between 7 and 15 years, of Italian nationality, from the family-home communities. The control group included 26 children (15 females and 11 males, aged between 7 and 15 years) of Italian nationality, matched for age and gender distribution with the study group, that were not in a socially disadvantaged condition. Collection of the plaque index (PI) was performed at t0. Then, all basic oral hygiene instructions were given to all children/adolescents and their educators. Education and motivation were repeated in the same way after 4–7 weeks (T1), and after 10–12 weeks (T2). The PI was taken also at T1 and T2. Results: An improvement in the PI was generally found in both groups, but there was no statistically significant difference between the two groups over time. Multivariate analysis of variance (MANOVA) revealed a statistically significant effect of time [F (1, 52) = 90.73, p < 0.001], regardless of the assignment group, in consequence of which the plaque index presented a moderate and significant improvement. Conclusion: The present data confirm the validity of the educational/motivational program to improve oral hygiene in children/adolescents, regardless of the assignment group.

Immediate Loading of Unsplinted Implant Retained Mandibular Overdenture: A Randomized Controlled Clinical Study

2019 ◽  
Vol 45 (5) ◽  
pp. 378-389 ◽  
Author(s):  
Ahmad Kutkut ◽  
Mohamed Rezk ◽  
Dominique Zephyr ◽  
Dolphus Dawson ◽  
Robert Frazer ◽  
...  
Keyword(s):  
Clinical Study ◽  
Survival Rate ◽  
Test Group ◽  
Immediate Loading ◽  
Control Group ◽  
Gingival Index ◽  
Implant Survival ◽  
Implant Stability ◽  
Treatment Groups ◽  
Implant Survival Rate

This clinical study aimed to clinically and radiographically compare the implant survival rate and peri-implant tissue response between immediate and delayed loading protocols for unsplinted implant retained mandibular overdentures. Twenty patients were enrolled to participate in this study. Each subject was randomly assigned to 1 of 2 treatment groups: test group patients' implants (n = 10), which were immediately loaded, and control group patients' implants (n = 10), which were conventionally loaded. Locator abutments were torqued to 15 Ncm at delivery. Attachments were picked up intraorally immediately after implant placement for the test group and at 3 months for the control group, and 3-lb retention inserts were placed. Marginal bone levels based on cone beam computed tomography fixed reference points were recorded at baseline and 12 months. Modified plaque index, gingival index, and implant stability quotients were recorded at baseline, 3 months, and 12 months. After 12 months, implant survival rate was 100% in both groups. Marginal bone levels, keratinized mucosa, modified plaque index, and gingival index were significantly different among the groups at 3- and 12-month intervals, whereas no significant differences were found in implant stability quotients between the groups. The fact that implant survival rate was 100% in both treatment groups suggests that, within the limitations of this study, immediate loading protocol for unsplinted implant retained mandibular complete overdenture is as predictable, safe, and successful as the delayed loading protocol. Implementing the immediate loading protocol for mandibular implant retained overdentures could shorten treatment time, which could lead to better patient's satisfaction.

scholarly journals Effect ofKangfuxinSolution on Chemo/Radiotherapy-Induced Mucositis in Nasopharyngeal Carcinoma Patients: A Multicenter, Prospective Randomized Phase III Clinical Study

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Yangkun Luo ◽  
Mei Feng ◽  
Zixuan Fan ◽  
Xiaodong Zhu ◽  
Feng Jin ◽  
...  
Keyword(s):  
Clinical Study ◽  
Nasopharyngeal Carcinoma ◽  
Adverse Events ◽  
Oral Mucositis ◽  
Rating Scale ◽  
Test Group ◽  
Phase Iii ◽  
Control Group ◽  
Oral Pain ◽  
Gastrointestinal Mucositis

Objective. To evaluate the efficacy and safety ofKangfuxinSolution, a pure Chinese herbal medicine, on mucositis induced by chemoradiotherapy in nasopharyngeal carcinoma patients.Methods. A randomized, parallel-group, multicenter clinical study was performed. A total of 240 patients were randomized to receive eitherKangfuxinSolution (test group) or compound borax gargle (control group) during chemoradiotherapy. Oral mucositis, upper gastrointestinal mucositis, and oral pain were evaluated by Common Terminology Criteria for Adverse Events (CTCAE) v3.0 and the Verbal Rating Scale (VRS).Results. Of 240 patients enrolled, 215 were eligible for efficacy analysis. Compared with the control group, the incidence and severity of oral mucositis in the test group were significantly reduced (P=0.01). The time to different grade of oral mucositis occurrence (grade 1, 2, or 3) was longer in test group (P<0.01), and the accumulated radiation dose was also higher in test group comparing to the control group (P<0.05). The test group showed lower incidence of oral pain and gastrointestinal mucositis than the control group (P<0.01). No significant adverse events were observed.Conclusion.KangfuxinSolution demonstrated its superiority to compound borax gargle on mucositis induced by chemoradiotherapy. Its safety is acceptable for clinical application.

scholarly journals C – reactive protein in saliva of non-smoking patients with periodontitis (a pilot study)

2021 ◽  
Author(s):  
Zerina Hadžić ◽  
Ivan Puhar
Keyword(s):  
Pilot Study ◽  
Test Group ◽  
Periodontal Therapy ◽  
Control Group ◽  
C Reactive Protein ◽  
Inflammatory Biomarker ◽  
Reactive Protein ◽  
Before And After ◽  
Oral Hygiene Instructions ◽  
And Control

Introduction: C-reactive Protein (CRP) as an inflammatory biomarker can be easily determined in saliva, but the values of salivary CRP in periodontitis are not well-studied. The aim of this study was to analyze and determine the values of salivary CRP in non-smokers with periodontitis stage 3 or 4 before and after supragingival and subgingival full-mouth periodontal therapy.Methods: Standard periodontal parameters and saliva samples were collected in 12 non-smoking patients. Patients in the test group (n = 6) underwent supragingival and subgingival full-mouth periodontal therapy, and the control group (n = 6) received only supragingival full-mouth therapy. Both groups received the same oral hygiene instructions in addition to therapy. After 3 months, re-registration of periodontal parameters and re-sampling of saliva for analysis of salivary CRP were done for both groups.Results: Statistical analysis revealed large differences in the values of clinical periodontal parameters and CRP levels in the test group after therapy. Values of salivary CRP in the test and control groups were lower 3 months the therapy; however, the results were not statistically significant. The correlation of clinical periodontal parameters and salivary CRP varied in both groups.Conclusion: Our pilot study reveals decreased concentrations of salivary C-reactive protein in non-smoking patients following non-surgical periodontal therapy. Further studies are needed to prove the reliability of salivary CRP as a biomarker for periodontitis.

Effect of Lactobacillus rhamnosus and Bifidobacterium lactis on gingival health, dental plaque, and periodontopathogens in adolescents: a randomised placebo-controlled clinical trial

2018 ◽  
Vol 9 (4) ◽  
pp. 593-602 ◽  
Author(s):  
A. Alanzi ◽  
S. Honkala ◽  
E. Honkala ◽  
A. Varghese ◽  
M. Tolvanen ◽  
...  
Keyword(s):  
Dental Plaque ◽  
Oral Care ◽  
Lactobacillus Rhamnosus ◽  
Test Group ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Periodontal Pathogens ◽  
Daily Consumption ◽  
Bifidobacterium Lactis ◽  
Gingival Health

To determine the effect of a probiotic combination of Lactobacillus rhamnosus GG (LGG) and Bifidobacterium lactis BB-12 on the gingival health, dental plaque accumulation, and the oral carriage of four putative periodontal pathogens in healthy adolescents. 108 schoolboys, aged 13-15 years, participated in this study. They were divided into two groups: probiotics (n=54) and placebo (n=54). Both groups received two probiotic-laced or placebo lozenges twice a day during a four-week period. Plaque Index (PI) and Gingival Index (GI) were recorded at baseline and after four weeks. Salivary and plaque carriage of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum were also monitored likewise. 101 subjects completed the study. A statistically significant reduction in GI was seen in the probiotic group as compared to the placebo group (P=0.012). A reduction in PI was found for both groups, with no difference observed between the groups after intervention (P=0.819). Probiotic lozenges significantly reduced levels of A. actinomycetemcomitans and F. nucleatum in saliva and plaque (P<0.05) and levels of P. gingivalis in plaque (P<0.05), while no significant changes were found in the control group. A significant reduction (P<0.001) was also noted in the total salivary bacterial counts of the test group. The short-term daily consumption of LGG and BB-12 probiotic lozenges improved the gingival health in adolescents and decreased the microbial counts of A. actinomycetemcomitans, and P. gingivalis. Hence probiotic supplements may serve as a simple adjunct to standard oral care for promoting the oral health in adolescents.

scholarly journals Comparative Study on the Efficacy of Commercially Available Chemical and Herbal Mouthwash against Oral Microorganisms

2021 ◽  
pp. 162-169
Author(s):  
M. Infant Reshawn ◽  
N. P. Muralidharan
Keyword(s):  
Test Group ◽  
Control Group ◽  
Yellow Colour ◽  
Mouth Rinses ◽  
Colony Forming Units ◽  
Dental Hospital ◽  
Food Particles ◽  
Mouth Wash ◽  
Oral Conditions ◽  
Oral Microorganisms

Aim: The present study was done to determine the activity of Naturally prepared  licorice mouthwash in comparison to chlorhexidine  mouthwash.         Introduction: Maintenance of oral hygiene is very important in preventing the growth of  a sticky film of bacteria and food particles that accumulates on teeth and hence Mouthwashes are prescribed in dentistry for treatment of several oral conditions and for prevention against various microorganisms. Licorice  is  derived  from "liquiritiae” which is  shrub or herb  and  the  yellow  colour  of it is  due to the flavonoids content of  the plant, which  includes liquiritin, isoliquiritin and other compounds. Herbal Mouthwashes (mouth rinses) are solutions or liquids intended to reduce the microbial load in the oral cavity. Materials and Methods: This study was conducted in Saveetha Dental Hospital, Chennai, Tamilnadu, India. The liquorice was extracted and formulated as mouth wash. Fig. 1 denotes the salivary samples were obtained from 20 volunteers (10 test group, 10 control group) and then, the participants were asked to  rinse their mouth with freshly prepared licorice mouthwash(test group),  chlorhexidine mouthwash (control group) and then paired saliva samples were obtained immediately after and before the mouthwash and finally the Colony forming units were recorded for pre and post usage of both the herbal and commercially available  mouthwash. Results: Study showed that there was a mean reduction in the colony-forming units with herbal mouthwash and Chlorhexidine mouth washes. Herbal mouthwash showed reduction in colony forming growth after usage of herbal mouthwash.

scholarly journals Clinical Assessment of Nifedipine-Induced Gingival Overgrowth in a Group of Brazilian Patients

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Cliciane Portela Sousa ◽  
Claudia Maria Navarro ◽  
Maria Regina Sposto
Keyword(s):  
Test Group ◽  
Plaque Index ◽  
Control Group ◽  
Gingival Inflammation ◽  
Drug Induced ◽  
Gingival Overgrowth ◽  
Dose Time ◽  
Clinical Index ◽  
Probing Depth ◽  
Treatment Control Group

Although it has been established that nifedipine is associated with gingival overgrowth (GO), there is little information on the prevalence and severity of this condition in the Brazilian population. The aim of this study was to assess the occurrence of nifedipine-induced GO in Brazilian patients and the risk factors associated using a Clinical Index for Drug Induced Gingival Overgrowth (Clinical Index DIGO). The study was carried out on 35 patients under treatment with nifedipine (test group) and 35 patients without treatment (control group). Variables such as demographic (age, gender), pharmacological (dose, time of use), periodontal (plaque index, gingival index, probing depth, clinical insertion level, and bleeding on probing), and GO were assessed. Statistical analysis showed no association between GO and demographic or pharmacological variables. However, there was an association between GO and periodontal variables, except for plaque index. According to our study, the Clinical Index DIGO can be used as a parameter to evaluate GO. Therefore, we conclude that the presence of gingival inflammation was the main risk factor for the occurrence of nifedipine-induced GO.

scholarly journals Effect of Lycopene in the Treatment of Periodontal Disease: A Clinical Study

2013 ◽  
Vol 14 (6) ◽  
pp. 1054-1059 ◽  
Author(s):  
Sphoorthi Anup Belludi ◽  
Shiras Verma ◽  
Ruchi Banthia ◽  
Prashanth Bhusari ◽  
Simran Parwani ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Clinical Study ◽  
Periodontal Disease ◽  
Clinical Signs ◽  
Test Group ◽  
Control Group ◽  
Scaling And Root Planing ◽  
Double Blind ◽  
Root Planing ◽  
Tomato Products

ABSTRACT Purpose Several epidemiologic studies have suggested a role of tomato products in decreasing the risk of the development of diseases related to oxidative stress (cancer and other chronic diseases). Oxidative stress may result in periodontal tissue damage either directly or indirectly. Lycopene, a powerful antioxidant and the main carotenoid in tomato products possesses the greatest quenching ability of singlet oxygen among the various carotenoids and is effective in protecting blood lymphocytes from NOO-radical damage. Hence, the aim of the present study is to compare the effect of systemically administered lycopene as an adjunct to scaling and root planing in patients with gingivitis and periodontitis. Materials and methods Twenty systemically healthy patients were involved in a randomized, double-blind, parallel study and based on their clinical signs were divided into two groups of mild to moderate periodontitis (A) and moderate gingivitis (B). The subjects under the groups A and B were randomly distributed between the two treatment groups: test group (n = 5), 4 mg lycopene/day for 2 weeks with oral prophylaxis (full mouth scaling and root planing (SRP) completed within 24 hours) and controls (n = 5), receiving only oral prophylaxis. Pre- and post-therapeutic periodontal parameters were evaluated. Results In group A, statistically significant improvement in CAL was reported in test group as compared to control group. In group B, the difference between pretreatment and post-treatment bleeding on probing scores was found to be statistically non-significant in both groups. Conclusion Results show that lycopene is a promising treatment modality as an adjunct to full mouth SRP of the oral cavity in patients with moderate periodontal disease. Clinical significance Modulation of the free radical production seems to be essential for the inhibition of tissue destruction, and treatment with antioxidants, like lycopene, which is the most potent among them will block the production of free ROS or its effects might prove to be therapeutically valuable. How to cite this article Belludi SA, Verma S, Banthia R, Bhusari P, Parwani S, Kedia S, Saiprasad SV. Effect of Lycopene in the Treatment of Periodontal Disease: A Clinical Study. J Contemp Dent Pract 2013;14(6):1054-1059.

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