scholarly journals Covid vaccine dilemma curbing the herd immunity in India- Jab or no jab?

Biomedicine ◽  
2021 ◽  
Vol 41 (4) ◽  
pp. 706-713
Author(s):  
Srinidhi Rai ◽  
Tirthal Rai ◽  
Sindhu H. ◽  
Shamantha Rai B. ◽  
Rithesh Pakkala P.

After the devastating second wave of COVID-19, with the rapid increase in the number of new cases in many states of India marking the beginning of a probable third wave of COVID-19, our best bet is taking a jab to protect against COVID-19. Currently, licensed vaccines are found to be reasonably safe and effective. The second wave of COVID-19 was devastating, but it's a silver lining to note that most of the individuals who had taken the jab recovered with mild infections, and the hospitalization rates among jabbed individuals were meager.  Various rumours related to the efficacy, safety, content, and side effects of the vaccine in India had caused a plunge in the vaccine acceptance rate leading to hesitancy and carelessness among the Indian population. This is a critical time for facts, not fear or rumors. This review provides an insight into the myths, pros and cons, and efficacy of the available vaccines.

Author(s):  
Sudarshan Ramaswamy ◽  
Meera Dhuria ◽  
Sumedha M. Joshi ◽  
Deepa H Velankar

Introduction: Epidemiological comprehension of the COVID-19 situation in India can be of great help in early prediction of any such indications in other countries and possibilities of the third wave in India as well. It is essential to understand the impact of variant strains in the perspective of the rise in daily cases during the second wave – Whether the rise in cases witnessed is due to the reinfections or the surge is dominated by emergence of mutants/variants and reasons for the same. Overall objective of this study is to predict early epidemiological indicators which can potentially lead to COVID-19 third wave in India. Methodology: We analyzed both the first and second waves of COVID-19 in India and using the data of India’s SARS-CoV-2 genomic sequencing, we segregated the impact of the Older Variant (OV) and the other major variants (VOI / VOC).  Applying Kermack–McKendrick SIR model to the segregated data progression of the epidemic in India was plotted in the form of proportion of people infected. An equation to explain herd immunity thresholds was generated and further analyzed to predict the possibilities of the third wave. Results: Considerable difference in ate of progression of the first and second wave was seen. The study also ascertains that the rate of infection spread is higher in Delta variant and is expected to have a higher threshold (>2 times) for herd immunity as compared to the OV. Conclusion: Likelihood of the occurrence of the third wave seems unlikely based on the current analysis of the situation, however the possibilities cannot be ruled out. Understanding the epidemiological details of the first and second wave helped in understanding the focal points responsible for the surge in cases during the second wave and has given further insight into the future.


2015 ◽  
Vol 4 (1) ◽  
pp. 57-80 ◽  
Author(s):  
Jennifer A. Zenovich ◽  
Shane T. Moreman

A third wave feminist approach to feminist oral history, this research essay blends both the visual and the oral as text. We critique a feminist artist's art along with her words so that her representation can be seen and heard. Focusing on three art pieces, we analyze the artist's body to conceptualize agentic ways to understand the meanings of feminist art and feminist oral history. We offer a third wave feminist approach to feminist oral history as method so that feminists can consider adaptive means for recording oral histories and challenging dominant symbolic order.


2021 ◽  
Vol 45 (1) ◽  
pp. 1-25
Author(s):  
Steven Ruggles

AbstractQuantitative historical analysis in the United States surged in three distinct waves. The first quantitative wave occurred as part of the “New History” that blossomed in the early twentieth century and disappeared in the 1940s and 1950s with the rise of consensus history. The second wave thrived from the 1960s to the 1980s during the ascendance of the New Economic History, the New Political History, and the New Social History, and died out during the “cultural turn” of the late twentieth century. The third wave of historical quantification—which I call the revival of quantification—emerged in the second decade of the twenty-first century and is still underway. I describe characteristics of each wave and discuss the historiographical context of the ebb and flow of quantification in history.


BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e048172
Author(s):  
Marie Fly Lindholt ◽  
Frederik Jørgensen ◽  
Alexander Bor ◽  
Michael Bang Petersen

ObjectivesThe management of the COVID-19 pandemic hinges on the approval of safe and effective vaccines but, equally importantly, on high vaccine acceptance among people. To facilitate vaccine acceptance via effective health communication, it is key to understand levels of vaccine scepticism and the demographic, psychological and political predictors. To this end, we examine the levels and predictors of acceptance of an approved COVID-19 vaccine.Design, setting and participantsWe examine the levels and predictors of acceptance of an approved COVID-19 vaccine in large online surveys from eight Western democracies that differ in terms of the severity of the pandemic and their response: Denmark, France, Germany, Hungary, Sweden, Italy, UK and USA (total N=18 231). Survey respondents were quota sampled to match the population margins on age, gender and geographical location for each country. The study was conducted from September 2020 to February 2021, allowing us to assess changes in acceptance and predictors as COVID-19 vaccine programmes were rolled out.Outcome measureThe outcome of the study is self-reported acceptance of a COVID-19 vaccine approved and recommended by health authorities.ResultsThe data reveal large variations in vaccine acceptance that ranges from 83% in Denmark to 47% in France and Hungary. Lack of vaccine acceptance is associated with lack of trust in authorities and scientists, conspiratorial thinking and a lack of concern about COVID-19.ConclusionMost national levels of vaccine acceptance fall below estimates of the required threshold for herd immunity. The results emphasise the long-term importance of building trust in preparations for health emergencies such as the current pandemic. For health communication, the results emphasise the importance of focusing on personal consequences of infections and debunking of myths to guide communication strategies.


2004 ◽  
Vol 94 (2) ◽  
pp. 444-448 ◽  
Author(s):  
James H. Price ◽  
Faith Yingling ◽  
Eileen Walsh ◽  
Judy Murnan ◽  
Joseph A. Dake

This study assessed differences in response rates to a series of three-wave mail surveys when amiable or insistently worded postcards were the third wave of the mailing. Three studies were conducted; one with a sample of 600 health commissioners, one with a sample of 680 vascular nurses, and one with 600 elementary school secretaries. The combined response rates for the first and second wave mailings were 65.8%, 67.6%, and 62.4%, respectively. A total of 308 amiable and 308 insistent postcards were sent randomly to nonrespondents as the third wave mailing. Overall, there were 41 amiable and 52 insistent postcards returned, not significantly different by chi-square test. However, a separate chi-square test for one of the three studies, the nurses' study, did find a significant difference in favor of the insistently worded postcards.


Author(s):  
Muhammed Elayadeth Meethal ◽  
Punnoth Poonkuzhi Naseef ◽  
Mohamed Saheer Kuruniyan ◽  
Mansoor C Abdulla ◽  
Shyju Ollakkod ◽  
...  

The global COVID-19 pandemic claiming global spread continues to evolve, now to the verge of a third wave of outbreak possibly caused by the novel variants of concern of severe acute respiratory syndrome corona virus-2 (SARS-CoV-2). The test positivity rate (TPR) and case fatal-ity rate (CFR) have increased steeply in the second wave of COVID-19 compared to the first. From the example of Kerala, a state in southern India, positivity increased from 1.33% at the peak of wave one in 10th June 2020 to 13.45% during 10th June 2021 in the second wave of pandemic. SARS-CoV-2 is an enveloped single-stranded RNA virus. Angiotensin-Converting Enzyme-2 (ACE-2) is a trans membrane surface protein present on multiple types of cells in the human body to which the viral spike protein attaches. Genetic variations in the SARS-CoV-2 and ACE2 receptor can affect the transmission, clinical manifestations, mortality and the efficacy of drugs and vaccines for COVID-19. Mutations are the primary cause of genetic variations. Given the high TPR and CFR, it is necessary to understand the variations of SARS-CoV-2 and cellular receptors of SARS-CoV-2 at the molecular level. In this review, we summarize the impact of genetic and ep-igenetic variations in determining COVID-19 pathogenesis and disease outcome.


2018 ◽  
pp. 19-27
Author(s):  
Grażyna STRNAD

The history of American women fighting for equal rights dates back to the 18th century, when in Boston, in 1770, they voiced the demand that the status of women be changed. Abigail Adams, Sarah Grimke, Angelina Grimke and Frances Wright are considered to have pioneered American feminism. An organized suffrage movement is assumed to have originated at the convention Elizabeth Stanton organized in Seneca Falls in 1848. This convention passed a Declaration of Sentiments, which criticized the American Declaration of Independence as it excluded women. The most prominent success achieved in this period was the US Congress passing the Nineteenth Amendment to the Constitution granting women the right to vote. The 1960s saw the second wave of feminism, resulting from disappointment with the hitherto promotion of equality. The second-wave feminists claimed that the legal reforms did not provide women with the changes they expected. As feminists voiced the need to feminize the world, they struggled for social customs to change and gender stereotypes to be abandoned. They criticized the patriarchal model of American society, blaming this model for reducing the social role of women to that of a mother, wife and housewife. They pointed to patriarchal ideology, rather than nature, as the source of the inequality of sexes. The leading representatives of the second wave of feminism were Betty Friedan (who founded the National Organization for Women), Kate Millet (who wrote Sexual Politics), and Shulamith Firestone (the author of The Dialectic of Sex: The Case for Feminist Revolution). The 1990s came to be called the third wave of feminism, characterized by multiple cultures, ethnic identities, races and religions, thereby becoming a heterogenic movement. The third-wave feminists, Rebecca Walker and Bell Hooks, represented groups of women who had formerly been denied the right to join the movement, for example due to racial discrimination. They believed that there was not one ‘common interest of all women’ but called for leaving no group out in the fight for the equality of women’s rights. They asked that the process of women’s emancipation that began with the first wave embrace and approve of the diversity of the multiethnic American society.


2021 ◽  
Vol 118 (25) ◽  
pp. e2104912118
Author(s):  
Katrin Schmelz ◽  
Samuel Bowles

What is an effective vaccination policy to end the COVID-19 pandemic? We address this question in a model of the dynamics of policy effectiveness drawing upon the results of a large panel survey implemented in Germany during the first and second waves of the pandemic. We observe increased opposition to vaccinations were they to be legally required. In contrast, for voluntary vaccinations, there was higher and undiminished support. We find that public distrust undermines vaccine acceptance, and is associated with a belief that the vaccine is ineffective and, if enforced, compromises individual freedom. We model how the willingness to be vaccinated may vary over time in response to the fraction of the population already vaccinated and whether vaccination has occurred voluntarily or not. A negative effect of enforcement on vaccine acceptance (of the magnitude observed in our panel or even considerably smaller) could result in a large increase in the numbers that would have to be vaccinated unwillingly in order to reach a herd-immunity target. Costly errors may be avoided if policy makers understand that citizens’ preferences are not fixed but will be affected both by the crowding-out effect of enforcement and by conformism. Our findings have broad policy applicability beyond COVID-19 to cases in which voluntary citizen compliance is essential because state capacities are limited and because effectiveness may depend on the ways that the policies themselves alter citizens’ beliefs and preferences.


2017 ◽  
Vol 40 (2) ◽  
pp. 155-182 ◽  
Author(s):  
Sverre Raffnsøe ◽  
Andrea Mennicken ◽  
Peter Miller

Since the establishment of Organization Studies in 1980, Michel Foucault’s oeuvre has had a remarkable and continuing influence on its field. This article traces the different ways in which organizational scholars have engaged with Foucault’s writings over the past thirty years or so. We identify four overlapping waves of influence. Drawing on Foucault’s Discipline and Punish, the first wave focused on the impact of discipline, and techniques of surveillance and subjugation, on organizational practices and power relations. Part of a much wider ‘linguistic’ turn in the second half of the twentieth century, the second wave led to a focus on discourses as intermediaries that condition ways of viewing and acting. This wave drew mainly on Foucault’s early writings on language and discourse. The third wave was inspired by Foucault’s seminal lectures on governmentality towards the end of the 1970s. Here, an important body of international research investigating governmental technologies operating on subjects as free persons in sites such as education, accounting, medicine and psychiatry emerged. The fourth and last wave arose out of a critical engagement with earlier Foucauldian organizational scholarship and sought to develop a more positive conception of subjectivity. This wave draws in particular on Foucault’s work on asceticism and techniques of the self towards the end of his life. Drawing on Deleuze and Butler, the article conceives the Foucault effect in organization studies as an immanent cause and a performative effect. We argue for the need to move beyond the tired dichotomies between discipline and autonomy, compliance and resistance, power and freedom that, at least to some extent, still hamper organization studies. We seek to overcome such dichotomies by further pursuing newly emerging lines of Foucauldian research that investigate processes of organizing, calculating and economizing characterized by a differential structuring of freedom, performative and indirect agency.


Author(s):  
Emily Ruth Rutter

In the second wave of black baseball works, African American playwrights, poets, and novelists uncovered an archive of feelings replete with the particular pains and pleasures of segregated life. The contemporary writers in the third wave place similar faith in literature as a way of knowing marginalized histories, while more deliberately foregrounding their own roles as mediators and curators of these histories. In ...


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