scholarly journals Impact of COVID-19 Variants on the Second Wave in India and Subsequent Discretion of Possibilities of the Third Wave

Author(s):  
Sudarshan Ramaswamy ◽  
Meera Dhuria ◽  
Sumedha M. Joshi ◽  
Deepa H Velankar

Introduction: Epidemiological comprehension of the COVID-19 situation in India can be of great help in early prediction of any such indications in other countries and possibilities of the third wave in India as well. It is essential to understand the impact of variant strains in the perspective of the rise in daily cases during the second wave – Whether the rise in cases witnessed is due to the reinfections or the surge is dominated by emergence of mutants/variants and reasons for the same. Overall objective of this study is to predict early epidemiological indicators which can potentially lead to COVID-19 third wave in India. Methodology: We analyzed both the first and second waves of COVID-19 in India and using the data of India’s SARS-CoV-2 genomic sequencing, we segregated the impact of the Older Variant (OV) and the other major variants (VOI / VOC).  Applying Kermack–McKendrick SIR model to the segregated data progression of the epidemic in India was plotted in the form of proportion of people infected. An equation to explain herd immunity thresholds was generated and further analyzed to predict the possibilities of the third wave. Results: Considerable difference in ate of progression of the first and second wave was seen. The study also ascertains that the rate of infection spread is higher in Delta variant and is expected to have a higher threshold (>2 times) for herd immunity as compared to the OV. Conclusion: Likelihood of the occurrence of the third wave seems unlikely based on the current analysis of the situation, however the possibilities cannot be ruled out. Understanding the epidemiological details of the first and second wave helped in understanding the focal points responsible for the surge in cases during the second wave and has given further insight into the future.

2017 ◽  
Vol 40 (2) ◽  
pp. 155-182 ◽  
Author(s):  
Sverre Raffnsøe ◽  
Andrea Mennicken ◽  
Peter Miller

Since the establishment of Organization Studies in 1980, Michel Foucault’s oeuvre has had a remarkable and continuing influence on its field. This article traces the different ways in which organizational scholars have engaged with Foucault’s writings over the past thirty years or so. We identify four overlapping waves of influence. Drawing on Foucault’s Discipline and Punish, the first wave focused on the impact of discipline, and techniques of surveillance and subjugation, on organizational practices and power relations. Part of a much wider ‘linguistic’ turn in the second half of the twentieth century, the second wave led to a focus on discourses as intermediaries that condition ways of viewing and acting. This wave drew mainly on Foucault’s early writings on language and discourse. The third wave was inspired by Foucault’s seminal lectures on governmentality towards the end of the 1970s. Here, an important body of international research investigating governmental technologies operating on subjects as free persons in sites such as education, accounting, medicine and psychiatry emerged. The fourth and last wave arose out of a critical engagement with earlier Foucauldian organizational scholarship and sought to develop a more positive conception of subjectivity. This wave draws in particular on Foucault’s work on asceticism and techniques of the self towards the end of his life. Drawing on Deleuze and Butler, the article conceives the Foucault effect in organization studies as an immanent cause and a performative effect. We argue for the need to move beyond the tired dichotomies between discipline and autonomy, compliance and resistance, power and freedom that, at least to some extent, still hamper organization studies. We seek to overcome such dichotomies by further pursuing newly emerging lines of Foucauldian research that investigate processes of organizing, calculating and economizing characterized by a differential structuring of freedom, performative and indirect agency.


2022 ◽  
Author(s):  
Rajesh Ranjan

India is currently experiencing the third wave of COVID-19, which began on around 28 Dec. 2021. Although genome sequencing data of a sufficiently large sample is not yet available, the rapid growth in the daily number of cases, comparable to South Africa, United Kingdom, suggests that the current wave is primarily driven by the Omicron variant. The logarithmic regression suggests the growth rate of the infections during the early days in this wave is nearly four times than that in the second wave. Another notable difference in this wave is the relatively concurrent arrival of outbreaks in all the states; the effective reproduction number (Rt) although has significant variations among them. The test positivity rate (TPR) also displays a rapid growth in the last 10 days in several states. Preliminary estimates with the SIR model suggest that the peak to occur in late January 2022 with peak caseload exceeding that in the second wave. Although the Omicron trends in several countries suggest a decline in case fatality rate and hospitalizations compared to Delta, a sudden surge in active caseload can temporarily choke the already stressed healthcare India is currently experiencing the third wave of COVID-19, which began on around 28 Dec. 2021. Although genome sequencing data of a sufficiently large sample is not yet available, the rapid growth in the daily number of cases, comparable to South Africa, United Kingdom, suggests that the current wave is primarily driven by the Omicron variant. The logarithmic regression suggests the growth rate of the infections during the early days in this wave is nearly four times than that in the second wave. Another notable difference in this wave is the relatively concurrent arrival of outbreaks in all the states; the effective reproduction number (Rt) although has significant variations among them. The test positivity rate (TPR) also displays a rapid growth in the last 10 days in several states. Preliminary estimates with the SIR model suggest that the peak to occur in late January 2022 with peak caseload exceeding that in the second wave. Although the Omicron trends in several countries suggest a decline in case fatality rate and hospitalizations compared to Delta, a sudden surge in active caseload can temporarily choke the already stressed healthcare infrastructure. Therefore, it is advisable to strictly adhere to COVID-19 appropriate behavior for the next few weeks to mitigate an explosion in the number of infections.


Biomedicine ◽  
2021 ◽  
Vol 41 (4) ◽  
pp. 706-713
Author(s):  
Srinidhi Rai ◽  
Tirthal Rai ◽  
Sindhu H. ◽  
Shamantha Rai B. ◽  
Rithesh Pakkala P.

After the devastating second wave of COVID-19, with the rapid increase in the number of new cases in many states of India marking the beginning of a probable third wave of COVID-19, our best bet is taking a jab to protect against COVID-19. Currently, licensed vaccines are found to be reasonably safe and effective. The second wave of COVID-19 was devastating, but it's a silver lining to note that most of the individuals who had taken the jab recovered with mild infections, and the hospitalization rates among jabbed individuals were meager.  Various rumours related to the efficacy, safety, content, and side effects of the vaccine in India had caused a plunge in the vaccine acceptance rate leading to hesitancy and carelessness among the Indian population. This is a critical time for facts, not fear or rumors. This review provides an insight into the myths, pros and cons, and efficacy of the available vaccines.


2021 ◽  
Author(s):  
Alexej Weber

Background and Aims: The reported case and death numbers of the coronavirus disease (COVID-19) are often used to estimate the impact of COVID-19. We observe that during the second half of the first and second waves, the COVID-19 deaths are significantly higher than the excess mortality. We attribute the difference to the pre-dying effect. We then compare the excess mortality to the official COVID-19 death numbers and calculate the infection fatality rates (IFRs) and the percentage of infected individuals from excess mortality for different age bands. We also compare the impact of COVID-19 to past influenza waves and analyze the vaccination effect on excess mortality. Methods: We forecast the baseline mortality from official data on deaths in Germany. Distributing a part of excess mortality into the near future, we lower the baseline simulating the pre-dying effect. From there, we compare the excess mortality to official COVID-19 deaths. From the observed mortality deficit, we estimate the percentage of infected individuals and then estimate the age-dependent IFRs. Results: In the first wave, we find an overall excess mortality of ca. 8 000. For the second wave, the overall excess mortality adds up to ca. 56 000. We find, that the pre-dying effect explains the difference between the official COVID-19 deaths and excess mortality in the second half of the waves to a high degree. Attributing the whole excess mortality to COVID-19, we find that the IFRs are significantly higher in the second wave. In the third wave, we find an excess mortality in mid-age bands which cannot be explained by the official COVID-19 deaths. For the senior band 80+, we find results in favor of a strong and positive vaccination effect for the third COVID-19 wave. Conclusions: We conclude that in the first and second COVID-19 waves, the COVID-19 deaths explain almost all excess mortality when the pre-dying effect is taken into account. In the third wave in 2021, the excess mortality is not very pronounced for the 80+ age band, probably due to vaccination. The partially unvaccinated 40-80 age group experiences a pronounced excess mortality in the third wave while there are too few official COVID-19 deaths to explain the excess. The no-vaccination scenario for the 80+ age band results in a similarly high excess mortality as for the more younger age bands, suggesting a very positive vaccination effect on reduction of COVID-19 deaths.


2021 ◽  
pp. 1-22
Author(s):  
Tofigh Maboudi ◽  
Ghazal P. Nadi ◽  
Todd A. Eisenstadt

Abstract Since the third wave of democracy, term limits have become a popular fixture of most constitutions intended to constrain the executive. Yet, recent constitutional reforms around the world show that presidents seeking re-election sometimes overturn the entire constitutional order to extend their power. What is the impact of these constitutional manipulations on the longevity of the executive in office? Using survival analysis of all political leaders and national constitutions from 1875 to 2015, this article demonstrates, for the first time, that when ‘authoritarian-aspiring’ presidents remove constitutional term limits, they increase their stay in office by more than 40%. Our findings contrast with a widely held position in the comparative authoritarian literature suggesting that dictators survive longer under institutional constraints. On the contrary, we argue that by removing constitutional barriers, rulers consolidate more power at the expense of their most ambitious allies and can stay in power longer.


2004 ◽  
Vol 94 (2) ◽  
pp. 444-448 ◽  
Author(s):  
James H. Price ◽  
Faith Yingling ◽  
Eileen Walsh ◽  
Judy Murnan ◽  
Joseph A. Dake

This study assessed differences in response rates to a series of three-wave mail surveys when amiable or insistently worded postcards were the third wave of the mailing. Three studies were conducted; one with a sample of 600 health commissioners, one with a sample of 680 vascular nurses, and one with 600 elementary school secretaries. The combined response rates for the first and second wave mailings were 65.8%, 67.6%, and 62.4%, respectively. A total of 308 amiable and 308 insistent postcards were sent randomly to nonrespondents as the third wave mailing. Overall, there were 41 amiable and 52 insistent postcards returned, not significantly different by chi-square test. However, a separate chi-square test for one of the three studies, the nurses' study, did find a significant difference in favor of the insistently worded postcards.


Author(s):  
Muhammed Elayadeth Meethal ◽  
Punnoth Poonkuzhi Naseef ◽  
Mohamed Saheer Kuruniyan ◽  
Mansoor C Abdulla ◽  
Shyju Ollakkod ◽  
...  

The global COVID-19 pandemic claiming global spread continues to evolve, now to the verge of a third wave of outbreak possibly caused by the novel variants of concern of severe acute respiratory syndrome corona virus-2 (SARS-CoV-2). The test positivity rate (TPR) and case fatal-ity rate (CFR) have increased steeply in the second wave of COVID-19 compared to the first. From the example of Kerala, a state in southern India, positivity increased from 1.33% at the peak of wave one in 10th June 2020 to 13.45% during 10th June 2021 in the second wave of pandemic. SARS-CoV-2 is an enveloped single-stranded RNA virus. Angiotensin-Converting Enzyme-2 (ACE-2) is a trans membrane surface protein present on multiple types of cells in the human body to which the viral spike protein attaches. Genetic variations in the SARS-CoV-2 and ACE2 receptor can affect the transmission, clinical manifestations, mortality and the efficacy of drugs and vaccines for COVID-19. Mutations are the primary cause of genetic variations. Given the high TPR and CFR, it is necessary to understand the variations of SARS-CoV-2 and cellular receptors of SARS-CoV-2 at the molecular level. In this review, we summarize the impact of genetic and ep-igenetic variations in determining COVID-19 pathogenesis and disease outcome.


2018 ◽  
pp. 19-27
Author(s):  
Grażyna STRNAD

The history of American women fighting for equal rights dates back to the 18th century, when in Boston, in 1770, they voiced the demand that the status of women be changed. Abigail Adams, Sarah Grimke, Angelina Grimke and Frances Wright are considered to have pioneered American feminism. An organized suffrage movement is assumed to have originated at the convention Elizabeth Stanton organized in Seneca Falls in 1848. This convention passed a Declaration of Sentiments, which criticized the American Declaration of Independence as it excluded women. The most prominent success achieved in this period was the US Congress passing the Nineteenth Amendment to the Constitution granting women the right to vote. The 1960s saw the second wave of feminism, resulting from disappointment with the hitherto promotion of equality. The second-wave feminists claimed that the legal reforms did not provide women with the changes they expected. As feminists voiced the need to feminize the world, they struggled for social customs to change and gender stereotypes to be abandoned. They criticized the patriarchal model of American society, blaming this model for reducing the social role of women to that of a mother, wife and housewife. They pointed to patriarchal ideology, rather than nature, as the source of the inequality of sexes. The leading representatives of the second wave of feminism were Betty Friedan (who founded the National Organization for Women), Kate Millet (who wrote Sexual Politics), and Shulamith Firestone (the author of The Dialectic of Sex: The Case for Feminist Revolution). The 1990s came to be called the third wave of feminism, characterized by multiple cultures, ethnic identities, races and religions, thereby becoming a heterogenic movement. The third-wave feminists, Rebecca Walker and Bell Hooks, represented groups of women who had formerly been denied the right to join the movement, for example due to racial discrimination. They believed that there was not one ‘common interest of all women’ but called for leaving no group out in the fight for the equality of women’s rights. They asked that the process of women’s emancipation that began with the first wave embrace and approve of the diversity of the multiethnic American society.


2021 ◽  
Vol 8 (9) ◽  
pp. 210699
Author(s):  
Calistus N. Ngonghala ◽  
James R. Knitter ◽  
Lucas Marinacci ◽  
Matthew H. Bonds ◽  
Abba B. Gumel

Dynamic models are used to assess the impact of three types of face masks (cloth masks, surgical/procedure masks and respirators) in controlling the COVID-19 pandemic in the USA. We showed that the pandemic would have failed to establish in the USA if a nationwide mask mandate, based on using respirators with moderately high compliance, had been implemented during the first two months of the pandemic. The other mask types would fail to prevent the pandemic from becoming established. When mask usage compliance is low to moderate, respirators are far more effective in reducing disease burden. Using data from the third wave, we showed that the epidemic could be eliminated in the USA if at least 40% of the population consistently wore respirators in public. Surgical masks can also lead to elimination, but requires compliance of at least 55%. Daily COVID-19 mortality could be eliminated in the USA by June or July 2021 if 95% of the population opted for either respirators or surgical masks from the beginning of the third wave. We showed that the prospect of effective control or elimination of the pandemic using mask-based strategy is greatly enhanced if combined with other non-pharmaceutical interventions (NPIs) that significantly reduce the baseline community transmission. By slightly modifying the model to include the effect of a vaccine against COVID-19 and waning vaccine-derived and natural immunity, this study shows that the waning of such immunity could trigger multiple new waves of the pandemic in the USA. The number, severity and duration of the projected waves depend on the quality of mask type used and the level of increase in the baseline levels of other NPIs used in the community during the onset of the third wave of the pandemic in the USA. Specifically, no severe fourth or subsequent wave of the pandemic will be recorded in the USA if surgical masks or respirators are used, particularly if the mask use strategy is combined with an increase in the baseline levels of other NPIs. This study further emphasizes the role of human behaviour towards masking on COVID-19 burden, and highlights the urgent need to maintain a healthy stockpile of highly effective respiratory protection, particularly respirators, to be made available to the general public in times of future outbreaks or pandemics of respiratory diseases that inflict severe public health and socio-economic burden on the population.


Author(s):  
Mohammed Xolile Ntshangase

Feminism has been a good movement with the noble aim of freeing the world from the shackles of an evil superiority of men over women. The principal of feminism as a movement was political equality between men and women. In itself, it was a fair and just course such that it was inclusive of men as well, men were also part of the movement with no insults, threats, and hate speech. But in this technological era some impurities have also crept into it. From the third wave of feminism which is also known as GRRRL feminism which turned the offensive names into jokes and somehow normal to be pronounced in public, things became no longer about equality and respect of humanity. As feminism grew, it became less critical and became more sensitive towards emotions and uncritical amassment of followers. To some extent, being critical about feminism is unacceptable because someone becomes quickly accused of being patriarchal and antifeminism. Indeed, patriarchy is a negative and destructive idea perpetrated by those who were suffering from testosteron-epowersyndrome . But, when some thinkers like Valenti, Arndt, and Harrow have identified the syndrome and implemented some medication to it, others inject the other side with similarly fatal ideas. I call those ideas Oestrgoen-powersyndrome because they make their victims think that with collapse of patriarchy, men should be disgraced and be made to feel not existentially necessary. Symptoms of this syndrome start from no more knowing that hating the other sex is wrong and should not be promoted. Writers like Annapuranny and Jansen even perpetrate non progressive talks like “what’s wrong with hating men”, “the world would be better off without men” and many phrases of such destructive nature. But the issue which this paper seeks to address is that there is no philosopher who has critically tackled this matter. In fact, some African philosophers rather reject the whole feminism movement as non-African. Using analytical framework, this research ventures into critical analysis of this issue of feminist extremism coupled with the silence of African philosophers.


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