scholarly journals Daily Versus Weekly Iron and Folic Acid Supplementation Regimen- A Randomized Parallel Open Label Trial among Reproductive Age Group Women in an Urban Poor Locality of Bengaluru

Healthline ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 21-27
Author(s):  
Vairavasolai P ◽  
Jayanthi Srikanth ◽  
Madhusudan M

Introduction:The global prevalence of anaemia in non-pregnant women is 30.2% and in India it is 56.2%.At least half the burden of anaemia is associated with iron deficiency. Women of reproductive age are at higher risk of developing iron deficiency because of losses during menstruation. Though Daily supplementation with iron and folic acid for a period of 3 months has been the standard as an approach for the prevention and treatment of iron deficiency anaemia among women of reproductive age, there has been limited success with the daily regimen in public health programmes, Intermittent use of oral iron supplements has been proposed as an effective alternative. Objectives: To compare the effectiveness of weekly and daily oral iron and folic acid therapy in improving the Hemoglobin levels among the reproductive age group women, adverse effects and compliance to both the regimens. Method:This was a comparative Randomized parallel open label trial conducted in an urban poor locality of Bengaluru conducted between January 2014 and January 2016. All the women in the reproductive age group (15-45 years) with mild to moderate anemia were included in the study. Sample size of 106 subjects was randomly allocated into the 2 groups (53 into weekly regimen and 53 into daily regimen). The subjects were supplemented with IFA tablets for 3 months according to their regimen. Results:Mean increase in Haemoglobin (Hb) in the daily group (1.92±1.1 g/dl) was significantly (P=<0.01) more when compared to that in the weekly group (0.91±0.82 g/dl). Incidence of all the Adverse Drug Reactions (ADRs) were more in the daily group compared to weekly group. However, the difference was only significant for abdominal pain and metallic taste (P=<0.01 and 0.02 respectively). The proportion of subjects reporting at least one ADR was also significantly more (P=<0.01) in the daily group compared to the weekly group. Compliance for weekly regimen (97.12%) was found to be significantly better(P=<0.01) when compared to that of the daily regimen (94.07%). Conclusions: Daily regimen was more effective in raising the hemoglobin levels when compared to weekly regimen. Incidence of abdominal pain and metallic taste were significantly more in the daily group compared to weekly group. Compliance for weekly regimen was significantly better when compared to that of the daily regimen.

Author(s):  
Mazharul Islam ◽  
Atiya Khan ◽  
Arish Mohammad Khan Sherwani

Introduction: Iron Deficiency Anaemia (IDA) is the most widespread micronutrient deficiency. Globally, nearly two billion people are affected by anaemia. This disease most often affects children, women of child-bearing age, and pregnant women. Nearly half of the pregnant women in the world are estimated to be anaemic. Its prevalence varies according to region and socio-economic conditions. The majority of those who are anaemic live in developing countries where the problem is exacerbated by limited access to inadequate resources and appropriate treatment. Aim: To find out the prevalence of IDA in the reproductive age group women and its associated factors. Materials and Methods: This hospital based, cross-sectional study was conducted among 400 females, of age group 15-49 years. After obtaining the written informed consent, eligible subjects were inquired about socio-demographic variables, socio-economic status, anthropometric measurements and risk factors. Required investigations were done. All the information was recorded on the semi-structured schedule form. Chi-square/Fisher’s-exact test was used to find the significance of study parameters on categorical scale between two or more groups. Results: Prevalence of IDA was found to be 42% (168/400). Prevalence of IDA was significant with habitat (p=0.0180), exercise (p=0.0004), amount of blood loss during menstruation (p<0.0001), duration of flow during menstruation, (p=0.0020), consumption of fish (p=0.0002), consumption of legumes (p=0.002), consumption of green leafy vegetable (p<0.0001). Conclusion: Results confirmed an increased prevalence of IDA in women of reproductive age group.


2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Yitayal Ayalew Goshu ◽  
Tewachew Muche Liyeh ◽  
Amare Simegn Ayele ◽  
Liknaw Bewket Zeleke ◽  
Yohannes Tesfahun Kassie

Introduction. Preconception folic acid supplementation is the provision of folate for reproductive age group women who have a plan to be pregnant. According to different studies, in African countries, there is poor utilization of preconception folic supplementation. So this study aimed at assessing women’s awareness on preconception care and its associated factors in Adet, Northwestern Ethiopia. Methods. A community-based cross-sectional study was conducted from March 1 to April 1, 2016, among 422 reproductive age group women. Systematic random sampling was used to get the study unit, and the data were collected using pretested structured questionnaire via face-to-face interview. The collected data were entered, cleaned, checked using EpiData version 3.1, and finally analyzed using SPSS version 20. Descriptive summary of the data was presented in terms of percentage and frequency. Binary and multiple logistic regressions were used in order to identify predictors using odds ratio at 95% confidence interval. Result. In this study, a total of 422 reproductive age group women participated with a response rate of 100%. Of a total of 422 participants, 67 (15.9%) of the women had good awareness on preconception folic acid supplementation. Women’s awareness on preconception folic acid supplementation was affected by having a chronic health problem, monthly household income, educational status, and a history of family planning use. Women who were educated (AOR 4.77, CI 1.85–6.98), had a history of family planning use (AOR 3.89, CI 1.77–8.55), had a chronic health problem (AOR 3.47, CI 2.68–5.98), and had a better monthly income (AOR 2.6, CI 2.05–6.76) had good awareness than their counterparts. Conclusion and Recommendation. This study concluded that women’s awareness on preconception folic acid supplementation was low. This finding suggests that there is a need to give emphasis and deliver health education about preconception folic acid supplementation for women.


2010 ◽  
Vol 17 (04) ◽  
pp. 686-690
Author(s):  
SHEZADI SABAH ◽  
MUSARAT RAMZAN ◽  
IRUM FATIMA

To determine the frequency of different causes of iron deficiency anemia in female patients of reproductive age group. 2) To determine the association between lack of balanced diet and iron deficiency anemia. Design: cross-sectional analytical study. Setting: Federal government services hospital, Islamabad. Period: From July 2008 to November 2008. Material and Methods: The study included female patients of reproductive age group i.e. 15-49 years of age having hemoglobin less than 11.5g/dl. The sampling technique was purposive. The data was analyzed using Microsoft excel 2000 and SPSS 10.0. Pearson correlation coefficient was used to determine the direction of relationship between total nutritional score and level of hemoglobin; student’s t-test was used to determine the significance of association. A pvalue of less than 0.05 was considered significant. Results: A positive correlation was observed between total nutritional score and level of hemoglobin (r = 0.402, p-value = 0.008). Correlation between animal protein and level of hemoglobin was 0.438 (p-value = 0.004) while between plant protein and level of hemoglobin was 0.211 (p-value = 0.179). Conclusions: It is concluded that there is a definite role of nutritional deprivation in the development of iron deficiency anemia. Lack of balanced diet especially protein group has much stronger association with thistype of anemia. Animal protein as compared to plant protein has strong association with the development of iron deficiency anemia. 


Author(s):  
Brindha Devi Jaganathan ◽  
Balachandran G.

A discovery is said to be an accident meeting a prepared mind. This quote is true when we happen to see certain rare cases which we could not diagnose unless we are aware. The aim of this presentation is to bring attention of cases like Iniencephaly, conjoined twins, Anencephaly to our medical fraternity and the need to focus still more on health need of the women in reproductive age group in particular. This is also to highlight the benefits of periconceptional Folic acid supplementation and need for intense antenatal surveillance programmes and proper genetic counselling to affected parents.


2021 ◽  
Vol 01 (01) ◽  
pp. 24-28
Author(s):  
Laxmi Shukla ◽  
◽  
Dimpal Singh ◽  
Ranjeet Kumar ◽  
Sabiya Khatoon ◽  
...  

Background of the study: Anemia continues to be a major public health problem in developing countries including India. It is the most common cause of malnutrition in the world and is the eighth leading cause of diseases in girls and women in developing counties. About one third of the global population is anemic (WHO 2010) [1]. Knowledge regarding the causes, prevention and management of iron deficiency among reproductive age women plays an important role in reducing the mortality and morbidity rates. The aim of this study is to assess the knowledge regarding iron deficiency anemia among reproductive age group women. Methodology: By using descriptive survey design, 50 women who met the criteria were selected by purposive sampling technique. Structured questionnaire was used to gather the data Data were analyzed by descriptive and inferential statistics. Results: Findings shows that 6% of reproductive age group women had inadequate level of knowledge regarding anemia, 72% had moderate level of knowledge and 22% of them had adequate level of knowledge. Conclusion: Overall findings of this study revealed that knowledge on iron deficiency anemia was inadequate among reproductive age group women. There is a need to improve the health care services, facilities and more importantly knowledge among the women on topics related to anemia and its prevention.


Author(s):  
Muhammed Nizamudheen C H ◽  
Soumya S B

This study is an attempt to clinically analyze the independent effect of Karimbirumbadi kashayam and Vasaguluchiadi kashayam in Panduroga and also compare their efficacy. Aims and Objectives: To evaluate the comparative efficacy of Karimbirumbadi kashayam and Vasaguluchyadi kashayam in Panduroga with special reference to iron deficiency anemia in the reproductive age group of women. Methodology: Among 46 registered subjects, 22 were registered in group A and 24were registered in group B. Out of which 20 subjects of A group and 20 subjects of B group completed the study. Group A was administered with 25ml of Karimbirumbadi kashayam with 40ml of luke warm water twice daily before food for 2 months and Group B was administered with 25ml of Vasaguluchyadi kashayam with 40ml of luke warm water and 10ml of Madhu as Anupana twice daily before food for 2 months. Objective and subjective parameters were analyzed using paired T test and Wilcoxon signed rank test respectively. Independent T test and Mann-Whitney U test were used to compare the parameters between the groups. Result: There was statistically significant improvement in the objective and subjective parameters (p<0.05 was observed). Conclusion: The study shows that both Karimbirumbadi kashayam and Vasaguluchyadi kashayam are effective in relieving the symptoms of Panduroga. Symptomatic relief was seen in both the group A & B, but there was no statistically significant difference between the groups in relieving these symptoms.


Author(s):  
Jayanta Saha ◽  
Sahana Mazumder Sen ◽  
Amalendu Samanta

Background: Iron deficiency anaemia is one of the most common nutritional disorders world-wide, especially in India and other developing countries. Young children and women in the reproductive age group are the most vulnerable to iron deficiency anaemia. Part of the reason for this lack of action is the fact that iron deficiency anaemia (IDA) has few overt symptoms. Hence this study have been undertaken to see the impact of nutritional counselling as a controlling measure of IDA.Methods: Rural women of reproductive age group were first screened for anemia and then for IDA. Two groups were formed one experimental group who were given nutritional counselling and another group designated as control group devoid of any such counselling. Baseline haematological indicators were estimated along with dietary surveys in both the groups. Haematological estimation and dietary survey was carried out again after six months and those women in experimental group still found to be anemic were again counselled, the procedure was repeated again at twelve months and at the end of the study that is eighteen months. Data’s were then statistically analysed for finding significant between the groups.Results: Our study showed statistically significant differences in haematological indicators between the experimental and control group at the end of the study. Intake of nutrition also showed statistically significant differences between the experimental and control group at the end of the study.Conclusions: Intervention only with iron and folic supplements is not adequate to tackle iron deficiency anemia problem. Therefore, there is a need to use interventions measures like nutritional education approaches for addressing major preventable causes of anemia. 


Sign in / Sign up

Export Citation Format

Share Document