The Analysis of Serum Leptin Concentration in Ssireum Players and Overweight and Normal Weight Individuals -According to the Body Composition, Exercise & Hormone Factors-

2008 ◽  
Vol 34 ◽  
pp. 1297-1305
Author(s):  
Young Jin Kim ◽  
Soon Ki Kim ◽  
Dong Ho Park ◽  
Shin Eon Lee
2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 976.2-976
Author(s):  
M. Novella-Navarro ◽  
B. Hernández-Breijo ◽  
F. Genre ◽  
L. Lera-Gómez ◽  
V. Pulito-Cueto ◽  
...  

Background:In recent years, the relationship between obesity and autoimmune diseases has taken interest, since adipose tissue has been identified as an endocrine organ that secretes cytokines (adipokines), among which leptin stands out as a soluble pro-inflammatory mediator associated with the body mass index (BMI).Objectives:The main objectives of this study are: i) to analyse the influence of BMI on clinical response in Rheumatoid Arthritis (RA) patients who initiate TNF-inhibitor (TNFi) therapy; ii) to analyse the differences in the serum profile of adipokines (leptin and adiponectin) according to BMI and their association with response to treatment.Methods:Observational study of a prospective cohort of 73 RA patients who initiated biological treatment with TNFi from the Complex Therapy Unit (CTU) of our Hospital. Patients were classified according to their BMI in normal-weight (BMI<25) and overweight/obesity (O/O) (IMC≥25). Demographic, clinical and laboratory variables were collected at baseline and at 6 months. Our outcome measures were DAS28-VSG remission (DAS28<2.6) at 6 months after TNFi initiation. Serum leptin and adiponectin levels were measured by Enzyme-Linked Immuno Sorbent Assay (ELISA) at baseline and 6 months. A descriptive sample analysis comparing the characteristics of both patient subgroups was performed using Chi-square, T-test for independent samples and U-Mann Whitney. Likewise, a bivariate analysis was carried out by means of binary logistic regression to assess the probable association of the parameters studied with remission.Results:Of the 73 patients studied, 51% were classified in O/O group. The O/O patients presented higher levels of baseline CRP (16.69±6.16 vs 8.74±3.81, p=0.01). No statistically significant differences were observed in the remaining variables (sex, age at the beginning of the TNFi, disease duration, baseline DAS-28), as well as therapeutic variables (use of previous DMARDs and doses of methotrexate and/or steroids). Patients with overweight/obesity presented higher DAS28-ESR values at 6 months of treatment (3.59±1.14 vs 2.93±1.27, p=0.02) and achieved remission less frequently (18.9% vs 48.6%, p=0.007). Serum leptin levels were significantly higher in O/O patients, both baseline (29.39±21.50 vs 13.49±8.78, p<0.001) and 6 months (33.06±22.03 vs 14.77±9.50, p<0.001) after TNFi initiation. In addition, O/O patients were less likely to reach remission at 6 months than normal-weight patients. [OR= 4.04 IC95% (1.40-11.64); p=0.009]. Lower frequency of remission was associated to greater leptin levels at 6 months [OR=0.94 CI95% (0.90-098); p=0.012]. No differences in serum adiponectin were found between both subgroups of patients.Conclusion:In this RA patient cohort, overweight/obesity is associated with i) a reduced response to TNFi therapy and ii) a lower short-term remission rate. Within the adipokine profile, leptin seems to play a relevant role in the maintenance of pro-inflammatory activity with a negative influence on the response to TNFi therapy in O/O patients.References:[1] Versini M. et al. Autoimmun Rev. 2014; 13, 981-1000[2] Toussirot E et al. Life Sci. 2015;140: 29-36.Disclosure of Interests:Marta Novella-Navarro: None declared, Borja Hernández-Breijo: None declared, Fernanda Genre: None declared, Leticia Lera-Gómez: None declared, Verónica Pulito-Cueto: None declared, Laura Nuño: None declared, Alejandro Villalba: None declared, Alejandro Balsa Grant/research support from: BMS, Roche, Consultant of: AbbVie, Gilead, Lilly, Pfizer, UCB, Sanofi, Sandoz, Speakers bureau: AbbVie, Lilly, Sanofi, Novartis, Pfizer, UCB, Roche, Nordic, Sandoz, Chamaida Plasencia: None declared


2020 ◽  
Vol 71 (1) ◽  
pp. 145-153 ◽  
Author(s):  
Gabriele Mascherini ◽  
Cristian Petri ◽  
Elena Ermini ◽  
Angelo Pizzi ◽  
Antonio Ventura ◽  
...  

AbstractSoccer referees are a specific group of the athletes’ population whose careers peak from 30 to 45 years old. An athlete's performance is not only determined by physical training but also by a lifestyle, e.g. eating habits. The purpose of this study was to verify current eating habits and resulting body composition of a group of elite international soccer referees. At an international FIFA seminar 60 elite international soccer referees (aged 39.2 ± 4.2 years) were enrolled. A body composition assessment was performed with skinfold thickness and bio impedance analysis, while eating habits were evaluated with a multi-pass 24-hour dietary recall. The body composition showed a normal weight condition with a fat content of 11.4 ± 2.5%. Macronutrients showed a low level of carbohydrates (43.6 ± 5.4%) and a high level of fat (40.0 ± 4.5%). Micronutrients showed a low level of calcium, potassium, zinc, magnesium, iodine, vitamin B12 and vitamin B9. Even though their body composition was within the normal range, the current eating habits of elite international soccer referees did not appear to follow the nutrition guidelines. Therefore, it would be advisable to provide knowledge on nutrition for this particular category of sports subjects, an individualized nutritional plan would be advisable, in order to achieve and maintain better performance and appropriate body composition for their role.


2018 ◽  
Vol 6 (4) ◽  
pp. 154 ◽  
Author(s):  
Fatih Kaya ◽  
Dilek Nar ◽  
Mustafa Said Erzeybek

In this study the effects of a 6 week spinning cycling training on the body composition of women were investigated. Twelve sedentary women (32-47 years old) voluntarily participated in this study. The 6-week training program consisted of exercise sessions on 3 days per week. The intensity of the training program that was kept low in the beginning was increased in the subsequent weeks. The training sessions including the warm-up and cool down lasted for 30-60 minutes. The analyses on the body compositions were measured regularly every week with bioelectrical impedance method. In data analysis descriptive statistics and repeated-measures analysis of variance were used. In the end of the 6-week spinning workouts positive changes were observed in many parameters related to body composition. Particularly after the 3rd week the significant changes recorded were noteworthy. At the end of the 6th week those who were overweight by World Health Organization (WHO) standards moved onto normal weight category and those who were obese became overweight. In conclusion it was seen that the spinning cycling workouts were seen as as effective method to lose weight and reduce the body fat ratio among women in this age group. This exercise method may be recommended for getting good results among obese and overweight women in a short period of time.


2021 ◽  
Vol 25 (1) ◽  
pp. 104-110
Author(s):  
José Miguel Soriano del Castillo ◽  
Paola Sechi ◽  
Pietro Marco Boselli

Introduction: Body mass index (BMI) provides little information on body composition. For example, two people with the same BMI might have different body compositions. In this sense, the development of a new BMI able to provide body composition information is of clinical and scientific interest. The aim of the study was to suggest a new modified BMI formula.Material and methods: A total of 108 subject, females 56 and males 52, 0-73 years old, in various physiopathological conditions were evaluated. Data were collected and processed by a program that through anthropometric measurements calculates classic BMI, volume, surface, V/S (that we can defined like a body-thickness “pseudospessore”) and the new BMI-BFMNU.Results: The basic formula (BMI =Body Mass [kg]/Height [m2]) uses the height squared as the value of the body surface, although this is only an approximation of the real surface, whereas using the real surface instead, the new BMI reflects better the ratio between the body volume and its surface. The ratio called "pseudospessore" is already used in literature from the BFMNU (Italian acronym refereed to Biologia e Fisiologia Modellistica della Nutrizione Umana) method and has been shown to be related to the amount of fat.Conclusions: Using the BMI-BFMNU, it is possible to obtain an indication of the body structure related to the amount of fat. The consequence is that the obtained numerical values do not coincide with the traditional BMI’s values and will refer to different normal ranges. For instance, a person may be in the range of normal weight for both BMI measurements, but only the BMI-BFMNU detects whether a person has a higher or lower fat content considering the individual’s category. This study opens up to new possible future developments on the application of the new BMI that will allow a more accurate assessment and classification of patients.


2015 ◽  
Vol 7 (1) ◽  
Author(s):  
Marcin Maciejczyk ◽  
Joanna Gradek ◽  
Jadwiga Szymura ◽  
Jerzy Cempla ◽  
Magdalena Więcek ◽  
...  

SummaryStudy aim: running economy (RE) is important indicator of endurance performance. During puberty dynamic changes in body composition and function are observed, as such RE is also expected to change. The aim of the study was to compare the running economy (RE) in overweight and normoweight boys during a running exercise performed with constant velocity, and the assessment of changes in RE during puberty.Material and methods: the RE of the subjects was evaluated twice: at the age of 11–12 and two years later. 18 overweight and 17 normal weight boys performed a graded test and a week later a submaximal run on a mechanical treadmill. During the exercise, physiological variables (oxygen uptake, heart rate, pulmonary ventilation, tidal volume and breathing frequency) were measured.Results: the intensity of work in both tests (%VO2max, %HRmax) was significantly higher in the overweight boys and decreased with age (non significantly) in both groups. The physiological response during the run in the overweight boys was significantly higher compared to normal weight. When the oxygen uptake was expressed as VO2.BM–0.75, the RE was similar in normal weight and overweight boys. During puberty, the inter-group differences in the metabolic cost of work stay at a relatively stable level.Conclusions: the lowered endurance performance in the overweight boys during puberty remains unchanged. The changes in physiological variables during puberty in both groups occurred in a similar way – the body composition did not influence the course of these changes in puberty.


2021 ◽  
Author(s):  
Florian Sibille ◽  
Jean-Baptiste Pretalli ◽  
Julienne Grillot

ABSTRACT Introduction Weight status perception (WSP) is the subjective assessment of one’s own body weight. It is not correlated with the body mass index (BMI). People practicing sports, including overweight people, tend to perceive themselves as normal weight. The military is in a paradoxical position between the need to gain muscle mass for professional purposes while respecting BMI standards. Using body composition might be more advantageous than using BMI as part of an individual approach in making a decision about fitness to serve. However, measuring body composition is not easy in current practice, and a bridge between WSP and body composition would make it possible to develop a simple assessment tool. Materials and Methods This was a prospective, descriptive, cross-sectional study. We collected sociodemographic data, anthropometric data, and WSP. Results Thirty-eight subjects were included. Among them, 71.1% were male. Mean age was 31.2 years (SD 8.9). The BMI was greater than 25 for 15 (39.5%) subjects. Twenty-four (63.2%) defined themselves as being overweight. Thirteen were overweight according to fat percentage (Fat%). A significant association (P = .008) was found between WSP and Fat%. Conclusion We were able to show a statistically significant association between WSP and Fat%. Such an association may be of great interest because the measurement of the Fat%, whatever the method used, is not easy in current practice. A replication of the study in the general population would be of great interest, especially since Fat% is closely associated with the incidence of cardiovascular diseases and many cancers.


2021 ◽  
pp. 23-26
Author(s):  
Erol Kovačević ◽  
Denis Čaušević ◽  
Yunyou Liu ◽  
Josipa Nakić ◽  
Nedim Čović ◽  
...  

Considering the growing global problem and the lack of obesity data in Bosnia and Herzegovina (BH) the main aim of this paper was to determine BH school-age children body composition and determine the differences in body composition between girls and boys classified in underweight, normal weight and overweight according to the body mass index (BMI) score. 2524 participants 1763 girls and 761 boys (aged 10-13 yrs.) from 32 elementary schools were randomly selected and divided to 3 BMI groups by WHO cut-off points. InBody 370 Body Composition Analyzer (BioSpace, Seoul, Korea), a segmental bioelectrical impedance analysis (BIA) device was used to gather data. The results showed ~38% of the sample were classified as overweight whilst gender differences showed higher body fat mass and fat percentages in arms, trunk and legs in underweight and normal weight girls and higher skeletal muscle mass in normal weight and overweight boys.


Open Medicine ◽  
2010 ◽  
Vol 5 (6) ◽  
pp. 724-732 ◽  
Author(s):  
Aliye Ozenoglu ◽  
Serdal Ugurlu ◽  
Gunay Can ◽  
Cihat Sarkis ◽  
Yeltekin Demirel

AbstractMorbidity of obesity-related diseases tends to increase due to a rise in the body mass index (BMI). We aimed to investigate how the body composition and biochemical parameters change while BMI increases in adult women were categorized as so: as normal weight, overweight and obese. Our objectives are to study the effects of those changes in the development of metabolic disturbances and to find out which parameters are the most sensitive to predict cardiometabolic risks. Three hundred and twenty two records of adult women (mean age: 38.62±12.71 year) who admitted to our unit concerning about losing or preserving their weights, were analyzed in the study. All patients had undergone anthropometric measurements and body composition analyses as well as some biochemical tests. Body composition analyses were performed by means of the Bioelectrical Impedance Analyzer (BIA). Increase in BMI significantly increased the body fat, blood sugar, insulin, triglyceride and uric acid levels. BMI and circumference of the waist were significantly and negatively correlated with the ratio of body water and lean mass/fat mass. However they were positively correlated with the ratio of fat mass and basal metabolism. Furthermore, it was also found that BMI and circumference of the waist were significantly and positively correlated with level of fasting blood sugar, insulin, triglyceride, homeostasis model assessment insulin resistance (HOMA-IR), uric acid and fibrinogen levels, and negatively correlated with high density lipoprotein (HDL) cholesterol level. In multiple regression analyses, circumference of waist measurements was significantly correlated with insulin, triglyseride and HDL, whereas the correlation between BMI and these parameters was not found significant. Total body fat mass (as %) showed significant correlation only with HDL-C level. It could be said that obesity which is a disorder that causes many health complications and affects the quality of life in the short and long term could be prevented or cured by keeping negative environmental conditions under control. According to our results, visceral adipose tissue (VAT) measurement was thought to be more related for metabolic and cardiovascular disorders rather than BMI. We also propose to test fasting blood glucose, insulin, triglyceride, HDL, fibrinogen, homocystein (HOM) levels along with VAT measurements to predict more truly about not only global cardiometabolic risk but also dementia in later life.


Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1091
Author(s):  
Kruti B. Shah ◽  
Steven D. Chernausek ◽  
Lori D. Garman ◽  
Nathan P. Pezant ◽  
Jasmine F. Plows ◽  
...  

Among all the body fluids, breast milk is one of the richest sources of microRNAs (miRNAs). MiRNAs packaged within the milk exosomes are bioavailable to breastfeeding infants. The role of miRNAs in determining infant growth and the impact of maternal overweight/obesity on human milk (HM) miRNAs is poorly understood. The objectives of this study were to examine the impact of maternal overweight/obesity on select miRNAs (miR-148a, miR-30b, miR-29a, miR-29b, miR-let-7a and miR-32) involved in adipogenesis and glucose metabolism and to examine the relationship of these miRNAs with measures of infant body composition in the first 6 months of life. Milk samples were collected from a cohort of 60 mothers (30 normal-weight [NW] and 30 overweight [OW]/obese [OB]) at 1-month and a subset of 48 of these at 3 months of lactation. Relative abundance of miRNA was determined using real-time PCR. The associations between the miRNAs of interest and infant weight and body composition at one, three, and six months were examined after adjusting for infant gestational age, birth weight, and sex. The abundance of miR-148a and miR-30b was lower by 30% and 42%, respectively, in the OW/OB group than in the NW group at 1 month. miR-148a was negatively associated with infant weight, fat mass, and fat free mass, while miR-30b was positively associated with infant weight, percent body fat, and fat mass at 1 month. Maternal obesity is negatively associated with the content of select miRNAs in human milk. An association of specific miRNAs with infant body composition was observed during the first month of life, suggesting a potential role in the infant’s adaptation to enteral nutrition.


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