scholarly journals Comparison of the Effectiveness of Chemo-mechanical and Traditional Caries Removal Methods in Primary Teeth Using Micro-Computed Tomography

2021 ◽  
Author(s):  
Melike Turgut-Coşgun ◽  
Firdevs Tulga-Öz ◽  
Mert Ocak ◽  
Kaan Orhan
Keyword(s):  
Caries Detection ◽  
Cavity Volume ◽  
Micro Computed Tomography ◽  
Mineral Density ◽  
Mechanical Method ◽  
Primary Molar ◽  
Significant Difference ◽  
Density Values ◽  
Molar Teeth ◽  
Caries Removal

Purpose: The purpose of this study was to evaluate dentin mineral density before and after caries removal with the traditional caries removal technique and chemo-mechanical method, with or without the use of caries detection dye. Our null hypothesis was that the chemo-mechanical method with minimally invasive treatment would achieve an effect similar to that of conservative pediatric dentistry treatment. Materials & Methods: Forty-eight medium-sized, interfacial decayed primary molar teeth without pulpal perforation were selected. Two groups were formed by Papacarie Duo and conventional method; then four sub-groups were formed by two caries detection dye applied or not applied groups, twelve teeth were randomly divided into each group. The teeth were then treated with chemo mechanical and traditional caries removal approach. Teeth were scanned with the same voxel sizes using micro-computed tomography images to figure out the difference dentin mineral density and to calculate the removed dentinal volume after chemo-mechanical or traditional method application. Results: The results showed increase of cavity volume in the chemo-mechanical and traditional method groups. No significant difference was found for cavity volume and dentinal carious volume in both groups (p>0.05). The mineral density values of demineralized dentin were between 0.52-0.66 g/cm3 before caries removal, and 1.39-1.59 g/cm3 after removing caries. These values were found to be within the range of healthy dentin mineral density values again without any significant difference between groups (p>0.05). Conclusion: In conclusion, chemo-mechanical methods can be used effectively for removing the caries in the primary molar teeth similar to conservative treatments.

scholarly journals Antibacterial Activity of Two Chemomechanical Caries Removal Gels on Carious Dentin of Primary Teeth: An in vitro Study

2016 ◽  
Vol 17 (12) ◽  
pp. 1027-1032 ◽  
Author(s):  
Hesham S Khalil ◽  
Shabnam Gulzar ◽  
Ruchi Arora ◽  
Altaf H Shah ◽  
Bhupendra Bhardwaj ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Primary Teeth ◽  
In Vitro Study ◽  
Antibacterial Activities ◽  
Viable Count ◽  
Primary Molar ◽  
Significant Difference ◽  
Molar Teeth ◽  
Caries Removal

ABSTRACT Introduction Chemomechanical caries removal (CMCR) is an effective method of caries removal especially for primary teeth as they cause less discomfort when compared with conventional caries removal. The most significant thing about caries removal is the elimination of cariogenic bacteria. This study compares the antibacterial activity of two CMCR gels. Materials and methods A total of 40 primary molar teeth with carious dentin were split along the long axis in a laboratory. Total viable count (TVC) was taken for the teeth before splitting as a measure of colony-forming units per milliliter (CFU/mL). Each half was treated with either Carisolv or Carie-Care CMCR gels. Clean dentin samples were evaluated for Streptococcus mutans (SM) and Lactobacillus acidophilus (LB) after removal of carious tissue using the caries removal gels using serial dilutions and incubating on specific agar plates. Results The results showed significant reduction in mean TVC after use of both the CMCR gels. Both gels reduced the CFU/mL of SM and LB to a significant level (p < 0.05). However, there was no significant difference between the antibacterial activities of the two CMCR gels. Conclusion The CMCR gels (Carisolv and Carie-Care) significantly reduced the residual TVC as well as SM and LB in carious primary dentin. Both CMCR gels had a similar antibacterial activity on the carious dentin of primary teeth. Clinical significance The CMCR gels tested have a significant antibacterial activity and can be effectively used for elimination of caries-causing bacteria in primary teeth. How to cite this article Gulzar S, Arora R, Shah AH, Bhardwaj B, Abusalim G, Khalil HS, Wyne AH. Antibacterial Activity of Two Chemomechanical Caries Removal Gels on Carious Dentin of Primary Teeth: An in vitro Study. J Contemp Dent Pract 2016;17(12):1027-1032.

scholarly journals A Clinical and Radiographic Assessment of Sodium Hypochlorite Versus Formocresol Pulpotomy in Primary Molar Teeth: 12-month Follow-up.

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Zahra Bahrololoomi ◽  
Fatemeh Zarebidoki ◽  
Atefeh Shakib
Keyword(s):  
Root Resorption ◽  
Clinical Success ◽  
Primary Molars ◽  
Pathologic Finding ◽  
Success Rates ◽  
Primary Molar ◽  
Exact Test ◽  
Significant Difference ◽  
Molar Teeth

Objective: The aim of this study was to compare the clinical and radiographic success rates of pulpotomy in primary molars using formocresol versus sodium hypochlorite.Methods:  Twenty-three children aged 4-9 years with at least two primary molars requiring pulpotomy were randomly allocated into two groups. All teeth received stainless steel crown after conventional pulpotomy procedure with either NaOCl or formocresol. Clinical and radiographic signs/symptoms were recorded at six and 12 months. Outcomes were statistically analyzed using Fisher’s exact test and Chi-squaretest.Results: Clinical success rates at 6 and 12-month follow-up in both groups was 100%. At 6-month follow-up, radiographic success rate for NaOCl and formocresol groups was 100%. At 12-month recalls, in NaOCl group, 20 teeth (87%) and in formocresol group, 21 teeth (91.3%) had radiographic success. No significant difference was found in the radiographic success rates at 12 months (P=1.00). Internal root resorption was the most common radiographic pathologic finding in both groups.Conclusion:Clinical and radiographic success rates in NaOCl group was comparable with formocresol group, so NaOCL can be suggested as an alternative for primary teeth pulpotomies. However further clinical studies with long-term follow-ups are needed. 

scholarly journals Age-Dependent Changes in Bone Architecture, Patterning, and Biomechanics During Skeletal Regeneration

2021 ◽  
Vol 9 ◽  
Author(s):  
Kevin Hoffseth ◽  
Emily Busse ◽  
Josue Jaramillo ◽  
Jennifer Simkin ◽  
Michelle Lacey ◽  
...  
Keyword(s):  
Bone Growth ◽  
Bone Architecture ◽  
Analysis Tool ◽  
Micro Computed Tomography ◽  
Mineral Density ◽  
Aged Mice ◽  
Intramembranous Bone ◽  
Significant Difference ◽  
Tomography Image ◽  
Computed Tomography Image

Mouse digit amputation provides a useful model of bone growth after injury, in that the injury promotes intramembranous bone formation in an adult animal. The digit tip is composed of skin, nerves, blood vessels, bones, and tendons, all of which regenerate after digit tip amputation, making it a powerful model for multi-tissue regeneration. Bone integrity relies upon a balanced remodeling between bone resorption and formation, which, when disrupted, results in changes to bone architecture and biomechanics, particularly during aging. In this study, we used recently developed techniques to evaluate bone patterning differences between young and aged regenerated bone. This analysis suggests that aged mice have altered trabecular spacing and patterning and increased mineral density of the regenerated bone. To further characterize the biomechanics of regenerated bone, we measured elasticity using a micro-computed tomography image-processing method combined with nanoindentation. This analysis suggests that the regenerated bone demonstrates decreased elasticity compared with the uninjured bone, but there is no significant difference in elasticity between aged and young regenerated bone. These data highlight distinct architectural and biomechanical differences in regenerated bone in both young and aged mice and provide a new analysis tool for the digit amputation model to aid in evaluating the outcomes for potential therapeutic treatments to promote regeneration.

scholarly journals Extrusion of Debris from Primary Molar Root Canals following Instrumentation with Traditional and New File Systems

2017 ◽  
Vol 18 (11) ◽  
pp. 1040-1044 ◽  
Author(s):  
Bhagyashree Thakur ◽  
Ajinkya M Pawar ◽  
Anda Kfir ◽  
Prasanna Neelakantan
Keyword(s):  
Primary Teeth ◽  
File Systems ◽  
Primary Molar ◽  
Group Iii ◽  
Root Canals ◽  
Group I ◽  
Significant Difference ◽  
Molar Teeth ◽  
Post Hoc ◽  
Root Canal Instrumentation

ABSTRACT Introduction To assess the amount of debris extruded apically during instrumentation of distal canals of extracted primary molars by three instrument systems [ProTaper Universal (PTU), ProTaper NEXT (PTN), and self-adjusting file (SAF)] compared with conventional stainless steel hand K-files (HF, control). Materials and methods Primary mandibular molars (n = 120) with a single distal canal were selected and randomly divided into four groups (n = 30) for root canal instrumentation using group I, HF (to size 0.30/0.02 taper), group II, PTU (to size F3), group III, PTN (to size X3), and group IV, SAF. Debris extruded during instrumentation was collected in preweighed Eppendorf tubes, stored in an incubator at 70°C for 5 days and then weighed. Statistical analysis was performed by one-way analysis of variance (ANOVA), followed by Turkey's post hoc test (p = 0.05). Results All the groups resulted in extrusion of debris. There was statistically significant difference (p < 0.001) in the debris extrusion between the three groups: HF (0.00133 ± 0.00012), PTU (0.00109 ± 0.00005), PTN (0.00052 ± 0.00008), and SAF (0.00026 ± 0.00004). Conclusion Instrumentation with SAF resulted in the least debris extrusion when used for shaping root canals of primary molar teeth. Clinical significance Debris extrusion in primary teeth poses an adverse effect on the stem cells and may also alter the permanent dental germ. Debris extrusion is rarely reported for primary teeth and it is important for the clinician to know which endodontic instrumentation leads to less extrusion of debris. How to cite this article Thakur B, Pawar AM, Kfir A, Neelakantan P. Extrusion of Debris from Primary Molar Root Canals following Instrumentation with Traditional and New File Systems. J Contemp Dent Pract 2017;18(11):1040-1044.

scholarly journals In vitro comparison of two types of digital X-ray sensors for proximal caries detection validated by micro-computed tomography

2020 ◽  
pp. 20200338
Author(s):  
Katrin Heck ◽  
Friederike Litzenburger ◽  
Verena Ullmann ◽  
Lea Hoffmann ◽  
Karl-Heinz Kunzelmann
Keyword(s):  
Exposure Time ◽  
Oxide Semiconductor ◽  
Caries Detection ◽  
Reference Standard ◽  
Micro Computed Tomography ◽  
Perfect Agreement ◽  
Proximal Caries ◽  
X Ray ◽  
Cmos Sensor ◽  
Significant Difference

Objectives: We aimed to compare the diagnostic accuracy of two intraoral digital X-ray sensors—the charged-coupled device (CCD) and complementary metal-oxide-semiconductor (CMOS)—for proximal caries detection in permanent molar and premolar teeth. Micro-CT served as the reference standard. Methods: 250 samples were mounted in three-dimensional (3D)-printed phantoms, and their proximal surfaces were evaluated by ICDAS criteria directly to create a balanced sample. Bitewing radiography was conducted using 3D-constructed X-ray phantoms with a CCD sensor at a 0.08 s and a CMOS sensor at 0.12 and 0.16 s exposure time. Two examiners determined the diagnostic decisions twice at appropriate intervals. Three diagnostic thresholds for sound surfaces and enamel and dentin caries were defined and presented in a cross-table. Sensitivity and specificity values and overall accuracy were calculated, and receiver operating curves were generated and compared. Reliability assessment was performed using linear weighted κ statistics. Results: The overall accuracies between the reference standard and different sensors and exposure times were 63.1% (CCD), 67.1% (CMOS sensor at 0.12 s) and 70.7% (CMOS sensor at 0.08 s). High specificity but low sensitivity values were found for all examination conditions at all thresholds. The area under the curve comparison values revealed no significant difference between sensor types and exposure times. Linear-weighted κ analysis revealed almost perfect agreement for all assessments. Conclusion: No significant difference was found for diagnostic performance of proximal caries detection between the different sensors and exposure times. The increased exposure time did not lead to a significant diagnostic benefit.

scholarly journals Comparison of endodontic disinfection of primary teeth root canals using rotary and reciprocating system: An in vitro study

2020 ◽  
Vol 9 (8) ◽  
pp. e457985882
Author(s):  
Lis de Amorim Fonseca ◽  
Raphael Amorim Cangussu ◽  
Arthur Soares de Oliveira ◽  
Sergio Luiz Pinheiro ◽  
Caleb Shitsuka ◽  
...  
Keyword(s):  
Primary Teeth ◽  
Brain Heart Infusion ◽  
Negative Control ◽  
Bacterial Reduction ◽  
Primary Molar ◽  
Universal System ◽  
Root Canals ◽  
Significant Difference ◽  
Molar Teeth

Aim: This experimental study in vitro aimed to compare the disinfection of the primary teeth root canals system using the rotary and reciprocating file system. Methodology: Forty-eight root canals from twenty-four primary molar teeth were contaminated with the standard strain of Enterococcus faecalis and randomically splitted into 4 groups (n=12). The Group PN comprised the root canals prepared with the ProTaperTM  Next rotary system. The Group WOG was defined by the usage of WaveOneTM Gold reciprocating system. The files from both systems were thermo mechanical processed. The Group PU used the ProTaperTM Universal system, with no thermic treatment, and the Group C (negative control) received no treatment. Samples from the root canals were collected with sterile paper points before and after its preparation, diluted and distributed in plates with Brain Heart Infusion (BHI) agar. The bacterial colonies were counted and the results were statistic analyzed by Wilcoxon and Kruskal-Wallis (Dunn) tests. Results: There was significant bacterial reduction using the systems (p>0,01). However, there was no significant difference among them (p<0,05) (PN=3.38; WOG=3.85; PU=3.26). Conclusion: Both systems (rotary and reciprocating) provide disinfectionon the primary molar teeth root canals system.

scholarly journals Salvianolate Ameliorates Osteopenia and Improves Bone Quality in Prednisone-Treated Rheumatoid Arthritis Rats by Regulating RANKL/RANK/OPG Signaling

2021 ◽  
Vol 12 ◽  
Author(s):  
Xiang Gao ◽  
Qingyun Wu ◽  
Xinle Zhang ◽  
Jia Tian ◽  
Dahong Liang ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Quality ◽  
Biomechanical Properties ◽  
Micro Computed Tomography ◽  
Mineral Density ◽  
Quality Deterioration ◽  
Inflammatory Conditions ◽  
Tnf Α ◽  
Significant Difference ◽  
High Bone

Rheumatoid arthritis (RA) is closely associated with periarticular osteopenia and leads to a high risk of generalized osteoporosis. Although glucocorticoid (GC) treatment ameliorates joint degradation and manages inflammation in RA, GC application may induce further bone quality deterioration in RA patients. Current treatments for RA lack relevant strategies for the prevention and treatment of osteopenia in RA. In this study, we aimed to investigate whether salvianolate treatment ameliorated osteopenia in prednisone-treated RA rats. Lewis rats with collagen-induced arthritis (CIA) were administered prednisone (PDN) or PDN plus salvianolate (PDN+Sal) treatment for 90 days. The effects of Sal were investigated in PDN-treated CIA rats. To further evaluate the effects of Sal under inflammatory conditions, we investigated the effects of Sal treatment on the TNF-α-induced inflammatory response in MC3T3-E1 osteoblasts. Bone histomorphometry, bone mineral density (BMD), bone biomechanical properties, micro-computed tomography (micro-CT), immunohistochemistry, RT-PCR and western blot analyses were performed to evaluate the effects of Sal. The results demonstrated that RA induced bone loss and bone quality deterioration, with high bone turnover in CIA rats. PDN+Sal treatment significantly increased BMD and trabecular/cortical bone mass, suppressed inflammation, and improved bone biomechanical properties compared to CIA control and PDN treatment. PDN+Sal treatment significantly suppressed bone resorption and the RANKL and RANKL/OPG ratios compared to PDN. PDN+Sal and PDN treatment significantly inhibited TNF-α by 82 and 83%, respectively, and both suppressed inflammation in CIA rats. However, there was no significant difference between PDN+Sal and PDN treatment alone in regard to bone formation parameters or the management of inflammation and arthropathy. Sal significantly increased Osterix, OPN, and Col1a1 while decreasing RANKL, TRAF6, and TRAIL gene in TNF-α-induced MC3T3-E1 osteoblasts. Sal significantly increased Osterix, OPN and RUNX2 while decreasing NF-κB, TRAF6 and IL-1β protein in TNF-α-induced MC3T3-E1 osteoblasts. The results suggested that salvianolate treatment ameliorated osteopenia and improved bone quality in prednisone-treated RA rats, and the potential mechanism may be related to the regulation of the RANKL/RANK/OPG signaling pathway, TRAIL-TRAF6-NFκB signal axis, and downregulation of inflammatory cytokines. Salvianolate could be used as a promising supplemental therapeutic strategy to ameliorate osteopenia and improve bone quality in GC-treated RA patients.

scholarly journals Micro-computed tomography and mechanical evaluation of trabecular bone structure in osteopenic and osteoporotic fractures

2017 ◽  
Vol 25 (1) ◽  
pp. 230949901769271 ◽  
Author(s):  
Fırat Ozan ◽  
Mahmut Pekedis ◽  
Şemmi Koyuncu ◽  
Taşkın Altay ◽  
Hasan Yıldız ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bone Structure ◽  
Structural Parameters ◽  
Osteoporotic Fractures ◽  
Biomechanical Properties ◽  
Compression Tests ◽  
Micro Computed Tomography ◽  
Mineral Density ◽  
Trabecular Thickness ◽  
Significant Difference

Purpose: Osteopenia and osteoporosis are the two most common musculoskeletal disorders in the elderly population. We determined whether osteopenic and osteoporotic patients with fractures exhibit differences in trabecular morphology and biomechanical properties of bone. Methods: Fourteen osteopenic patients and 28 osteoporotic patients with hip fractures who underwent hemiarthroplasty for proximal femoral fractures caused by low-energy injury were included. Bone mineral density (BMD) measurements were performed. Compression tests and high-resolution micro-computed tomography were used to assess cancellous bone samples obtained from the principal compressive region of the femoral head. Results: The BMD values were lower in the osteoporotic patients than in the osteopenic patients ( p < 0.05). There was a significant difference in the yield stress values between the groups ( p < 0.05). However, no significant differences in the strain energy density, stiffness and Young’s modulus were observed between the groups ( p > 0.05). The mean maximum stress was significantly higher in the osteoporotic patients than in the osteopenic patients ( p < 0.05). Although structural parameters, including bone volume (BV), BV fraction, trabecular thickness, trabecular connectivity density and trabecular number, were higher in the osteopenic patients, the differences were not significant ( p > 0.05). Trabecular separation values were significantly higher in the osteoporotic patients ( p < 0.05). Conclusion: Our results showed that the trabecular morphology and biomechanical properties of bone were not significantly different between osteopenic and osteoporotic patients in terms of some parameters.

scholarly journals Calcium-Enriched Mixture Pulpotomy of Primary Molar Teeth with Irreversible Pulpitis. A Clinical Study

2016 ◽  
Vol 10 (1) ◽  
pp. 43-49 ◽  
Author(s):  
Mahtab Memarpour ◽  
Soleiman Fijan ◽  
Saeed Asgary ◽  
Marzieh Keikhaee
Keyword(s):  
Day Treatment ◽  
Radiographic Evaluation ◽  
Complete Relief ◽  
Radiographic Assessment ◽  
Primary Molar ◽  
Cem Cement ◽  
Vital Pulp Therapy ◽  
Significant Difference ◽  
Molar Teeth ◽  
Irreversible Pulpitis

Objectives:To evaluate the outcome of vital pulp therapy in primary teeth with irreversible pulpitis by using calcium-enriched mixture (CEM) cement according to clinical and radiographic assessment.Participants and Methods:Fifty primary molar teeth with irreversible pulpitis in 50 children aged 6-8 years underwent pulpotomy using CEM cement as the dressing material. Following pulpotomy, pain intensity was evaluated by use of a visual analog scale at 1 and 7 days from the treatment and in clinical appointments at 3, 6 and 12 months after baseline. Radiographic evaluation was performed at 6 and 12 months. Data were analyzed using the McNemar test.Results:A total of 42 children (mean age 7.26 ± 0.82 year) completed the study. After one day treatment 56 % of children reported complete relief of pain and after 7 days 62% reported the same. However, two children complained of increased pain 1 day after treatment. None of the children reported pain in the subsequent appointments. One child complained of tenderness in percussion after 6 months. Pulp canal obliteration was the most common change in the radiographic assessment. There was no significant difference between clinical (92.8%) and radiographic (90.4%) success (p=0.990).Conclusion:Pulpotomy using CEM cement could present a successful treatment in primary molar teeth with irreversible pulpitis.

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