scholarly journals The role of Amalaki Churna in the management of Shvetpradar

2020 ◽  
Vol 4 (06) ◽  
Author(s):  
Pallvi Tukaram Jadhvar
Keyword(s):  
Ayurvedic Medicine ◽  
Excessive Secretion

 Pradar is most common gynecological problem found in striroga O.P.D. Pradar is characterized by excessive secretion of white and reddish discharge from vagina. If discharge is white in color is called Shvetpradar . Leucorrhoea is not disease but a symptom of so many diseases according to charaka and vagbhata. According to Ayurveda Leucorrhoea is termed as Shvetpradar. Leucorrhoea is excessive white or yellowish, non-purulent, non-offensive, non purulent. Shvetpradar a condition characterized with white discharge non associated with pain. Amalaki Churna is classical ayurvedic medicine used in Shvetpradara. Charaka has given information about Amalaki Churna in chikitasa sthana.

scholarly journals ROLE OF BILWADI AGADA IN PREVENTION OF COVID - 19

2020 ◽  
Vol 8 (7) ◽  
pp. 3939-3944
Author(s):  
Varun Rajpuria ◽  
Anitta James
Keyword(s):  
Prevention And Control ◽  
Distress Syndrome ◽  
The Body ◽  
Ayurvedic Medicine ◽  
Pharmacological Properties ◽  
Upper Respiratory Tract ◽  
Corona Virus ◽  
Upper Respiratory ◽  
And Control

Agada Tantra is a specialized branch of Ayurveda which mainly deals with Visha (Poison) and its management mainly through special formulations called Agada Yogas which counteract the deleterious actions of poison over the body. There are numerous such formulations which are unique because of their potent ingredients and fast action. Bilwadi Agada is one among such Yogas. In December 2019, a series of acute atypical respiratory disease occurred in Wuhan and then rapidly spread to other areas. It was soon discovered that a novel Corona Virus was responsible, and this was named as the Severe Acute Respiratory Syndrome Corona Virus-2 (2019) due to its high homology to SARS-CoV-2 which caused Acute Respiratory Distress Syndrome and high mortality during 2002–2003 in China. According to Ayurveda, this novel Corona is a Jangama Visha as it is of zoonotic origin. It affects the upper respiratory tract so is the movement of Jangama Visha which moves upward and affects those areas. It is also mentioned in Ayurvedic treatise that the Jangaman Visha should be treated with Sthavara dravyas. Bilwadi gutika is an Ayurvedic medicine prepared from thirteen medicinal plants triturated in goat’s urine. When we compare the primary symptoms of COVID-19 and the indications of Bilwadi gutika, we can see so many similarities. The main objective of this article is to discuss the therapeutic and pharmacological properties of Bilwadi Agada and thereby understanding its role in prevention and control of COVID-19 pandemic.

Chinese Medicinal Excrement

2017 ◽  
Vol 12 (1-2) ◽  
pp. 139-169
Author(s):  
Catherine Despeux
Keyword(s):  
Tang Dynasty ◽  
Ayurvedic Medicine ◽  
Cow Dung ◽  
Transfer Of Knowledge ◽  
Scholarly Literature ◽  
The Tang Dynasty ◽  
Chinese Texts ◽  
Privileged Site ◽  
Indian Physician

AbstractThe use of medicinal excrement, of which there is some evidence under the Han, increased significantly in the Tang Dynasty. Many recipes, recorded in the Dunhuang manuscripts and in scholarly literature, are based on animal excrement. First, we want to show that this increase is due to the influence of foreign medicines, mainly Āyurvedic medicine and, second, that Buddhism played a key role in this development. By comparing Indian medical sources, Chinese manuscripts from Dunhuang (which was a privileged site for the transfer of knowledge), Chinese texts of scholarly literature, and Buddhist sources, the role of Buddhism in spreading the use of medical excrement can be observed. Buddhism first exerted an ethical influence through the idea of compassion for beings suffering from illness, which then led to the search for first-aid remedies that were cheap and easy to procure, especially in the natural environment, such as the feces of domestic animals. The notion was then conveyed that, beyond the tension between pure and filthy, no remedy is vile and every substance can be a remedy, an idea that can be traced back to Āyurvedic medicine and that is embedded in the story of the model Indian physician, Jīvaka. Finally, the circulation and distribution of animal fecal recipes (here we have taken the example of cow dung) follows the passage of Buddhism from India to China as does the dissemination of such remedies. Thus, we show that Buddhism was a catalyst and a vector for the transmission and transfer of knowledge on medicinal excrement.

scholarly journals The Versatile Role of Matrix Metalloproteinase for the Diverse Results of Fibrosis Treatment

Molecules ◽  
2019 ◽  
Vol 24 (22) ◽  
pp. 4188 ◽  
Author(s):  
Hong-Meng Chuang ◽  
Yu-Shuan Chen ◽  
Horng-Jyh Harn
Keyword(s):  
Extracellular Matrix ◽  
Wound Healing ◽  
Cardiovascular Diseases ◽  
De Novo ◽  
Biological Processes ◽  
Tissue Formation ◽  
Ecm Degradation ◽  
Excessive Secretion ◽  
Wound Tissue

Fibrosis is a type of chronic organ failure, resulting in the excessive secretion of extracellular matrix (ECM). ECM protects wound tissue from infection and additional injury, and is gradually degraded during wound healing. For some unknown reasons, myofibroblasts (the cells that secrete ECM) do not undergo apoptosis; this is associated with the continuous secretion of ECM and reduced ECM degradation even during de novo tissue formation. Thus, matrix metalloproteinases (MMPs) are considered to be a potential target of fibrosis treatment because they are the main groups of ECM-degrading enzymes. However, MMPs participate not only in ECM degradation but also in the development of various biological processes that show the potential to treat diseases such as stroke, cardiovascular diseases, and arthritis. Therefore, treatment involving the targeting of MMPs might impede typical functions. Here, we evaluated the links between these MMP functions and possible detrimental effects of fibrosis treatment, and also considered possible approaches for further applications.

scholarly journals Ayurveda: The Conventional Indian Medicine System and its Global practice

2019 ◽  
pp. 13-33 ◽  
Author(s):  
Snehal Shah
Keyword(s):  
Life Style ◽  
Herbal Medicines ◽  
Market Value ◽  
Global Perspective ◽  
Medical Emergency ◽  
Ayurvedic Medicine ◽  
Nutrition Supplement ◽  
Nutritional Needs ◽  
Indian Medicine

The word "Ayurveda" meaning knowledge of life and longevity. Rather than frequent usage of Medicines in common disorders, Ayurvdic medicines are as good as food which serve role of the nutritional needs.  Because of the changing in life style and carelessness towards sickness with respect to time as well as money, people are growing modernization some traditional ways. Now a days, There has been increased global interest in traditional medicine. In this dissertation, attempted to brief history along with worldwide concepts of Ayurveda and availability of Ayurvedic medicines which play roles in medical emergency, surgical emergency and traditional one as nutrition supplement. Moreover, WHO contribution in global acceptance of Ayurveda reflected in this paper  reveals worldwide usage of Ayurveda medicines. Opportunity and challenges with global perspective of Ayurvedic medicine and gold time for modernization presented in this concept paper gives idea about market value for herbal medicines.

scholarly journals Runx2 overexpression compromises bone quality in acromegalic patients

2018 ◽  
Vol 25 (3) ◽  
pp. 269-277 ◽  
Author(s):  
Maria Teresa Valenti ◽  
Monica Mottes ◽  
Samuele Cheri ◽  
Michela Deiana ◽  
Valentina Micheletti ◽  
...  
Keyword(s):  
Bone Quality ◽  
Bone Fractures ◽  
Bone Microarchitecture ◽  
Mineral Density ◽  
High Fracture ◽  
Osteoblastic Activity ◽  
Analysis And Evaluation ◽  
Poor Predictor ◽  
Excessive Secretion

Acromegalic patients, characterized by excessive secretion of GH and IGF-1, show a high fracture risk but bone mineral density is a poor predictor for bone fractures in these patients. The effects of an excess of GH/IGF1 on skeleton as well as on osteogenic progenitors, i.e. mesenchymal stem cells, have not been investigated in these patients. We aimed to elucidate the skeletal conditions of acromegalic patients by means of bone microarchitecture analysis and evaluation of MSCs osteogenic commitment. In particular, we performed histomorphometric analyses, and we quantified the expression levels of the osteogenic transcription factor RUNX2 in circulating MSCs. Our results showed an abnormal microarchitecture and demonstrated that bone impairment in acromegalic patients is associated with the upregulation ofRUNX2expression. Furthermore, osteoblastic activity was significantly reduced in patients under pharmacological treatment, compared to untreated patients. In conclusion, this study demonstrates the key role ofRUNX2gene overexpression in causing bone impairment in acromegalic patients. It also suggests a therapeutic approach for the improvement of bone quality, focused on the osteoblastic lineage rather than the inhibition of osteoclastic activity.

The role of antacids in diseases related to excessive secretion of hydrochloric acid

2021 ◽  
Vol 77 (7) ◽  
pp. 425-434
Author(s):  
Marcin Janiaczyk ◽  
Magdalena Ogrodowczyk
Keyword(s):  
Hydrochloric Acid ◽  
Excessive Secretion

A double arm clinical study to access the role of Basti and Virechana Karma along with Vanari Yoga in Premature Ejaculation

2019 ◽  
Vol 4 (04) ◽  
Author(s):  
Shrinivasraddi G. Venkaraddiyavar ◽  
Prashanth A. S. ◽  
S. G. Chavan
Keyword(s):  
Clinical Study ◽  
Treatment Modality ◽  
Positive Emotion ◽  
Premature Ejaculation ◽  
Ayurvedic Medicine ◽  
Inclusion Criteria ◽  
The Core ◽  
Group A ◽  
Group B

Satisfaction is a pleasant or positive emotion. It can also be a feeling. If a Satisfaction during intercourse and fertility agents are intact then the whole intension will be lost. Ayurvedic medicine plays important role in the patients who are in deep depression due to dissatisfaction and infertility in the field of Andrology. Gati is the core characteristic concerned with any disorder of Vata. If Shukra Dhatu gets vitiated by Vata Dosha causes Shukragata Vata. Here 40 subjects diagnosed with Shukragata Vata w.s.r to Premature Ejaculation fulfilling the Inclusion criteria were selected for study and randomly categorized into two groups as Group A and Group B each consisting of 20 subjects. Group A received Amapachana with Hareetakyadi Churna, Tritiya Baladi Yapana Basti was administered in Yoga Basti schedule, later Vanari Yoga granules given as a Shamanoushadi. Group B received Amapachana with Hareetakyadi Churna, Sadhyosnehapana with Shalmali Ghrita. Sarvanga Abhyanga with Murchitatila Taila followed by Sarvanga Swedana and Sneha Virechana was administered with Eranda Taila. After Samsarjana Krama, Vanari Yoga granules was given as a Shamanoushadi. So the objective of the study is to establish such a treatment modality which can be helpful in treating the Shukragata Vata.

Synthesis and secretion of pepsinogen in the rat; effects of alteration of adrenal activity and of body hydration

1959 ◽  
Vol 196 (4) ◽  
pp. 837-840 ◽  
Author(s):  
Basil I. Hirschowitz ◽  
William G. Underhill
Keyword(s):  
Gastric Secretion ◽  
Isotonic Saline ◽  
Release Mechanism ◽  
Hypotonic Solution ◽  
Synthesis Mechanism ◽  
Pylorus Ligation ◽  
Pepsinogen Secretion ◽  
Excessive Secretion ◽  
Gastric Secretions

Simultaneous measurements of peptic activity were made in the stomach wall and in gastric secretions collected after 2 hours of pylorus ligation. These measurements allowed interpretation of alterations of pepsin secretion in terms of residual stored pepsinogen. Two mechanisms were differentiated as having an influence on pepsinogen secretion: a ‘release mechanism,’ whereby pepsinogen was retained in the cell and a ‘synthesis mechanism,’ whereby inadequate synthesis of enzyme resulted in depression of pepsinogen secretion. Thus the injection of 5% dextrose, in this case acting as a hypotonic solution caused inhibition of the release mechanism, similar to that seen with atropine, whereas adrenalectomy reduced the synthesis of pepsinogen which resulted in a diminished output of enzyme, without affecting the release mechanism. Isotonic saline injections stimulated the secretion of, and as a result increased the synthesis of pepsinogen. Adrenalectomy reduced gastric secretion of acid as well as pepsinogen; effects that were grossly exaggerated by salt withdrawal, which also resulted in an excessive secretion of sodium into the stomach. ACTH given for 1–3 weeks, by contrast with the adrenal insufficiency state, did not stimulate gastric secretion, emphasizing again the trophic or permissive rather than stimulant role of the adrenal cortex in gastric secretory mechanisms.

scholarly journals Role of Interleukin-18 (IL-18) during Lethal Shock: Decreased Lipopolysaccharide Sensitivity but Normal Superantigen Reaction in IL-18-Deficient Mice

2000 ◽  
Vol 68 (6) ◽  
pp. 3502-3508 ◽  
Author(s):  
Peter Hochholzer ◽  
Grayson B. Lipford ◽  
Hermann Wagner ◽  
Klaus Pfeffer ◽  
Klaus Heeg
Keyword(s):  
Serum Levels ◽  
Peritoneal Macrophages ◽  
Wild Type ◽  
Degree Of Sensitization ◽  
Lethal Shock ◽  
Ifn Γ ◽  
Excessive Secretion ◽  
Deficient Mice

ABSTRACT Lethal shock can be associated with excessive secretion of cytokines such as tumor necrosis factor (TNF) and gamma interferon (IFN-γ). IFN-γ mediates macrophage activation and appears to be controlled by interleukin (IL)-12 and IL-18. To investigate the role of IL-18 in vivo, we generated IL-18-deficient mice by gene targeting. IL-18−/− mice showed decreased sensitivity towards lipopolysaccharide (LPS)-induced shock. LPS-induced IFN-γ production was abrogated, yet induction of IL-12 and TNF was not affected. Both wild-type and IL-18-deficient mice succumbed to LPS-induced lethal shock after sensitization with d-galactosamine. However, in marked contrast to LPS, the bacterial superantigenStaphylococcus aureus enterotoxin B (SEB) induced comparable serum levels of IFN-γ in IL-18+/+ and IL-18−/− mice, accompanied by an upregulation of cell surface markers CD14, CD122 (IL-2Rβ), and CD132 (IL-2Rγ) on peritoneal macrophages. Moreover, SEB injection rendered IL-18-deficient mice sensitive for subsequent challenge with LPS. The degree of sensitization was comparable to that in wild-type controls with respect to lethality. However, LPS-induced TNF levels in serum were significantly reduced in SEB-sensitized IL-18-deficient mice. These results imply that IL-18 plays an important role in induction of IFN-γ and lethality in response to LPS.

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